Mechanical signaling regulates vascular smooth muscle cell adaptation in aging by Amin Mohajeri, Song Yi Shin, Samuel Padgham, Devon J. Boland, Dana Pittman Ratterree, Jacob Blizman, Gang Han, Christopher R. Woodman, Andreea Trache, Andreea Trache

“…To dissect the mechanisms involved, the structural and functional properties of VSM cells were assessed by using mechanical stimulation combined with fluorescence confocal microscopy. …”
Get full text

Targeting macrophages and ion homeostasis in T2D: new genes and therapeutic pathways identified by Lisha Mou, Lisha Mou, Tony Bowei Wang, Ying Lu, Ying Lu, Zijing Wu, Zijing Wu, Yuxian Chen, Ziqi Luo, Xinyu Wang, Zuhui Pu, Zuhui Pu

“…Machine learning models were developed to predict T2D, and structural predictions of the hub proteins were performed. …”
Get full text

STREAM: a system for tracing radiative transfer and energy balance in heterogeneous surfaces by Tengyuan Fan, Zunjian Bian, Jean-Louis Roujean, Huaguo Huang, Hua Li, Junhua Bai, Biao Cao, Yongming Du, Qing Xiao, Qinhuo Liu

“…To address this problem, this study introduces a system for tracing radiative transfer and energy balance in heterogeneous surfaces, hereafter called STREAM, in which the three-dimensional structural heterogeneity is obtained through LiDAR data and a voxel-based radiosity method is proposed for radiative transfer process. …”
Get full text

Why do patients with isolated PCL rupture experience no subjective knee joint instability during walking? An in vivo biomechanical study by Mingfeng Lu, Mingfeng Lu, Wei Chen, Jinpeng Lin, Jinpeng Lin, Wenhan Huang, Junqing Gao, Junqing Gao, Lilian Zhao, Shilin Li, Lilei He, Yu Zhang

“…ObjectiveThe aim of this study is to assess the kinematic changes in the knee joint during walking in patients with isolated PCL-deficiency (PCLD) to determine the presence of walking-related joint instability (mechanical instability—abnormal displacement form structural damage). Additionally, the study seeks to provide biomechanical insights into the observed differences between subjective and objective assessments.Methods35 healthy volunteers and 27 patients with isolated PCLD (both involved and uninvolved sides) were included in the study. …”
Get full text

Risk Factors, Clinical Characteristics, and Antibiotic Susceptibility Patterns of <i>Streptococcal</i> Keratitis: An 18-Year Retrospective Study from a Tertiary Hospital in China by Zhen Cheng, Qingquan Shi, Bo Peng, Zijun Zhang, Zhenyu Wei, Zhiqun Wang, Yang Zhang, Kexin Chen, Xizhan Xu, Xinxin Lu, Qingfeng Liang

“…IVCM revealed deeper inflammatory cell distribution and structural disruption as the disease progressed. Resistance rates of aminoglycosides, β-lactams, and fluoroquinolones have increased, with significant differences among species for amikacin (<i>p</i> = 0.010), gentamicin (<i>p</i> = 0.007), and others. …”
Get full text

Multimission Observations of Relativistic Electrons and High-speed Jets Linked to Shock-generated Transients by Savvas Raptis, Martin Lindberg, Terry Z. Liu, Drew L. Turner, Ahmad Lalti, Yufei Zhou, Primož Kajdič, Athanasios Kouloumvakos, David G. Sibeck, Laura Vuorinen, Adam Michael, Mykhaylo Shumko, Adnane Osmane, Eva Krämer, Lucile Turc, Tomas Karlsson, Christos Katsavrias, Lynn B. Wilson III, Hadi Madanian, Xóchitl Blanco-Cano, Ian J. Cohen, C. Philippe Escoubet

“…Energetic electrons initially accelerated upstream are shown to remain broadly confined within the transmitted transient structures downstream, where they get further energized due to the elevated compression levels potentially by betatron acceleration. …”
Get full text

Laser-induced Breakdown Spectroscopy Based on Pre-classification Strategy for Quantitative Analysis of Rock Samples by Weiheng KONG, Lingwei ZENG, Yu RAO, Sha CHEN, Xu WANG, Yanting YANG, Yixiang DUAN, Qingwen FAN

“…BACKGROUNDLIBS technology is a non-destructive, high sensitivity, high resolution spectroscopy technology that can be used to analyze the composition and structure of chemical substances and materials. It has extensive application in fields such as chemistry, materials science, life science, and geological exploration, and its emergence has provided new methods and technologies for the development of these fields. …”
Get full text

Research progress of fuel ethanol refining and life cycle carbon footprint by Pan LI, Lulu ZHANG, Hai CHEN, Xingguo WU, Wei CHEN, Jing BAI, Chun CHANG, Junhao HU

“…Power consumption is a major contributor to acidification potential and global warming potential, indicating a need for new technologies or alternative power structures can be developed to reduce environmental impact. …”
Get full text

Analizar los rasgos definitorios de un currículo de formación de profesionales de la salud basados en interculturalidad de una facultad de medicina: analizado desde la fenomenograf... by Claudia Pérez Acuña, José Luis Medina

“…The implementation of experiential and practical teaching methodologies, as well as the adaptation of institutional structures, are essential to overcome the challenges presented by teaching of this. …”
Get full text

Clinicopathological characterization of Switch/Sucrose-non-fermentable (Swi/Snf) complex (ARID1A, SMARCA2, SMARCA4)-deficient endocervical adenocarcinoma by Chao Cao, Zi-Yun Wu, Wei Liao, Li-Jun Wei, Hao-Yu Liang, Xia Yang, Rong-Zhen Luo, Li-Li Liu

“…Morphologically, Swi/Snf-deficient ECA displayed frequent poor differentiation (P = 0.001), medullary features (P < 0.001), high nuclear grade (P < 0.001), necrosis (P = 0.001), stromal tumor-infiltrating lymphocytes (sTILs, P < 0.001), peritumoral lymphocyte aggregation (P = 0.001), and tertiary lymphoid structures (TLS, P < 0.001). Immune subset analysis revealed significantly elevated densities of CD3⁺ T cells, CD8⁺ T cells, CD38⁺ plasma cells, CD56⁺ NK cells, CD68⁺ macrophages, and PD-1⁺ T cells in Swi/Snf-deficient ECA (P < 0.05). …”
Get full text

Do rating agencies consider the social capital of the firm in their ratings? by C.S. Agnes Cheng, Peng Guo, Cathy Zishang Liu, Jing Zhao, Sha Zhao

“…This sheds light on the dynamics between social structures and financial outcomes. Methodologically, our use of the 9/11 attacks as an exogenous shock to measure changes in social capital introduces a novel approach to study similar phenomena. …”
Get full text

The Palaeomeander at Vrakuňa, SW Slovakia and the historical Topography of the fording Point (Toll) on Žitný Ostrov Island / Vrakunský paleomeander a historická topografia mýtneho... by PIŠÚT, Peter, SZWARCZEWSZKI, Piotr, SMOLSKA, Ewa, RUSINKO, Adam

“…Furthermore, lateral erosion clarifies why fortification structures in Vrakuňa and neighbouring Prievoz have failed to survive, notwithstanding their mention in 15th-Century charters and display on the respective villages‘ coat-of-arms. …”
Get full text

Research Progress on the Effect of Dissolved Organic Matter on the Environmental Behavior of Cadmium in Environmental Remediation by Jiabao MA, Siwen LIU, Bo WANG, Di WU, Jixin WEI, Qing SUN, Chenge MA, Yi HUANG, Taotao YAN

“…DOM has complex and diverse sources, components, and structures, under different conditions, DOM exhibits two effects on Cd: passivation or activation, which has been widely used in in situ passivation remediation, leaching remediation, or phytoremediation of Cd pollution. …”
Get full text

Retrospective Analysis of Tooth Preparation Done by Postgraduate Trainees for Monolithic Zirconia Restorations by Sourav Maji, Sayan Majumdar, Samiran Das, Sreya Kundu, Soumadip Niyogi, Shubhabrata Roy, Jayanta Bhattacharyya, Soumitra Ghosh

“…The preparations were assessed by a single evaluator using 3D designing software (Cerec SW 20.0, inLab SW 20.0, Dentsply Sirona) for occlusal clearance, finish line design, finish line width, finish line quality, surface finish, undercuts, and iatrogenic injury to adjacent structures. A 3D software (Geomagic Control X 2024.1.0) was used to create cross-sections of the prepared tooth from the STL files, and measurements were taken for Occluso-Cervical Height (OCH) and Total Occlusal Convergence (TOC). …”
Get full text

Tissue-Specific Expression Analysis and Functional Validation of <i>SiSCR</i> Genes in Foxtail Millet (<i>Setaria italica</i>) Under Hormone and Drought Stresses, and Heterologous... by Yingying Qin, Ruifu Wang, Shuwan Chen, Qian Gao, Yiru Zhao, Shuo Chang, Mao Li, Fangfang Ma, Xuemei Ren

“…Both <i>SiSCR</i> genes exhibited nearly identical secondary structures and physicochemical profiles, with promoter analyses revealing five conserved <i>cis</i>-regulatory elements. …”
Get full text

Surface morphology segmentation and evaluation of diamond lapping pad based on improved Mask R-CNN by Wenlong SUO, Yanfen LIN, Congfu FANG

Get full text

Evaluation of Simulated Weightlessness Model of Hindlimb Unloading Miniature Pigs and Their Tissue Damage by TU Yingxin, JI Yilan, WANG Fei, YANG Dongming, WANG Dongdong, SUN Zhixin, DAI Yuexin, WANG Yanji, KAN Guanghan, WU Bin, ZHAO Deming, YANG Lifeng

“…Objective To establish a weightlessness simulation animal model using miniature pigs, leveraging the characteristic of multiple systems’ tissue structures and functions similar to those of humans, and to observe pathophysiological changes, providing a new method for aerospace research. …”
Get full text

Review of Research on Foundation Scour of River-Crossing Bridges by WANG Lu, LIU Hong-wei, WEI Kai, Bruce Melville, NIE Rui-hua

“…In terms of physical mechanisms, most existing studies focus on bridge foundation scour under simplified boundary conditions such as straight channels, non-cohesive riverbeds, and cylindrical structures. However, cohesive sediments prevalent in natural rivers exhibit complex force interactions and high randomness, resulting in scour processes for bridge foundations that differ significantly from those in non-cohesive riverbeds. …”
Get full text

Ecological-environmental consequences of urban sprawl in rural settlements around the Hamedan city by Naser Shafiei Sabet, Sogand Khaksar

“…According to the results, it can be seen that in current situation of Iran, the research undertaken on the marginal area of Hamedan is consistent with the researches of Yagre, Ewing, Morot and Hernandez and other researchers who have discussed environmental issues and the lack of supportive policies to impede the spread of these structures in Europe. Conclusion: In studies on spatial development and land use change of agricultural lands, it is important to note the parameters that undergo change progressively as opposed to those that change more rapidly. …”
Get full text

Tectonic transition and extension at the eastern and western ends of the Altyn Tagh fault: insights from triple junctions by YI Kexin, JOLIVET Marc, GUO Zhaojie

“…Resolving this debate requires clarifying how the ATF evolved into its present configuration and how it connects with adjacent structures such as the Qilian orogenic belt and the Qimantagh-Eastern Kunlun fault. …”
Get full text