Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects by Jeongah Oh, Sneha Muralidharan, Qing Zhao, Johannes Scholz, Iris D. Zelnik, Shani Blumenreich, Tammar Joseph, Tamir Dingjan, Pradeep Narayanaswamy, Hyungwon Choi, Heiko Hayen, Federico Torta, Anthony H. Futerman

“…The sphingolipidome contains thousands of structurally distinct sphingolipid (SL) species. This enormous diversity is generated by the combination of different long-chain bases (LCBs), N-acyl chains and head groups. …”
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Insights from one American Indian tribe about heart health by Sarah de Loizaga, McCall Miller, Barbie Giambra, LeCario Benashley, Billie Bones, Samantha Buonfiglio, Gwendena Lee Gatewood, Amanda Paxson, Teresa Pestian, Rachel Sarnacki, Rhiannon Walker, Dawnafe Whitesinger, Andrea Beaton, Lisa M. Vaughn

“…Methods: We used qualitative semi-structured interviews to examine Tribal experiences and perspectives surrounding heart health and health in general on Tribal lands. …”
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Sociodemographic factors associated with trajectories of depression among urban refugee youth in Kampala, Uganda: A longitudinal cohort study by Zerihun Admassu, Sikky Shiqi Chen, Carmen H. Logie, Moses Okumu, Frannie MacKenzie, Robert Hakiza, Daniel Kibuuka Musoke, Brenda Katisi, Aidah Nakitende, Peter Kyambadde, Lawrence Mbuagbaw

“…Sociodemographic (older age, gender [cisgender women vs. cisgender men], longer time in Uganda), and socioecological (structural: unemployment, food insecurity; interpersonal: parenthood, recent intimate partner violence) factors were significantly associated with the sustained high trajectory of depression. …”
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Empowering knowledge graphs with hybrid retrieval-augmented generation for the intelligent mix scheme of mass concrete by Yuqing Shang, Zhijiang Ke, Peng Lin, Qianhui Ren, Wenshan Zhang, Xiongwu Wang, Xiaotao Li, Fuyuan Gong, Shiqi Wang, Baofa Wang, Zhengkui Xu, Minglun Sun, Shunli Tan

“…Firstly, a total of 1723 mix proportioning records collected from 15 hydropower stations were structurally extracted using a customized data transformation tool. …”
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Uncovering the breeding contribution of transposable elements from landraces to improved varieties through pan-genome-wide analysis in rice by Xiaoxia Li, Xiaoxia Li, Xiaofan Dai, Xiaofan Dai, Huiying He, Wu Chen, Qian Qian, Qian Qian, Lianguang Shang, Lianguang Shang, Longbiao Guo, Wenchuang He

“…Advances in pan-genomes and enhanced capacity for analyzing structural variations have increasingly highlighted their role in rice genetic improvement. …”
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Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies by Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone

“…Bioinformatics predictions based on both phylogenetic conservation and functional/structural software were used to characterize the new identified variants. …”
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A mixed-methods assessment of the Australasian Society of Genetic Counselors (ASGC) Mentor Program by Holly Canton, Rebecca Macintosh, Joanna Sweeting, Helen Mountain, Jodie Ingles, Amy Nisselle, Erin Turbitt, Alison McEwen, Laura Yeates

“…Methods: We used an explanatory mixed-method design with cross-sectional surveys deployed at baseline and follow-up and opt-in semi-structured interviews. Interview transcripts were analyzed using codebook thematic analysis, and data were integrated in a narrative approach. …”
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Preoperative subjective impairments in language and memory in brain tumor patients by Lena Rybka, Lena Rybka, Lena Rybka, Roel Jonkers, Roel Jonkers, Milena Burzlaff, Milena Burzlaff, Tizian Rosenstock, Tizian Rosenstock, Peter Vajkoczy, Thomas Picht, Thomas Picht, Katharina Faust, Adrià Rofes, Adrià Rofes

“…Group and subgroup analyses were conducted to provide general and tumor grade specific data.Results48.4% of patients mentioned co-occurrence of language and memory impairments in reading, writing, and conversation. …”
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The Effects of Foot and Mouth Disease on the Profitability of Smallholder Dairy Farms: Evidence from East Java, Indonesia by Nanang Febrianto, Budi Hartono, Eko Nugroho, Anie Eka Kusumastuti, Priyo Sugeng Winarto, Puji Akhiroh, Trinil Susilawati, Aulia Puspita Anugra Yekti, Putri Utami, Nurul Nadia Ramli, Muhammad Helmi

“…output analysis, economic losses were quantified on the basis of structured surveys and secondary data from affected dairy farmers. …”
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The use of technology and mobile health apps in child maltreatment interventions: Perspectives of TF-CBT therapists and SafeCare providers by Manderley Recinos, Kathryn O'Hara, Ashwini Tiwari, Daniel J. Whitaker, Christine Wekerle, Shannon Self-Brown

“…Data collection and analysis was guided by qualitative descriptive analysis. …”
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Investigating The Performance Of Local And Indigenous Businesses In Times Of Economic Recession With Emphasis On Developing The Capabilities Of Cooperatives In Sistan And Baluchest... by Ali Asghar Tabavar, Abdoulnaser Derakhshan, Sahar Arefi

“…The first step in carrying out the estimation approach of vector error correction models is to check the meanness of the data. Therefore, the significance of all variables is checked and if some of them are insignificant, the significance variables are formed using measurement methods. …”
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Study on the Impact of Hormone Therapy for Prostate Cancer on the Quality of Life and the Psycho-Relational Sphere of Patients: ProQoL by Francesca Cappuccio, Carlo Buonerba, Luca Scafuri, Rossella Di Trolio, Pasquale Dolce, Serena Orsola Trabucco, Filomena Erbetta, Elvira Tulimieri, Antonella Sciscio, Concetta Ingenito, Antonio Verde, Giuseppe Di Lorenzo

“…Methods Eligible men initiating hormonal therapy were recruited between December 2021 and December 2023. Data were collected at baseline (T 0) and after 3 months (T 1) and 6 months (T 2) of ADT using standardized questionnaires (European Organization for Research and Treatment of Cancer [EORTC] QLQ-C30, EORTC QLQ-PR25) and semi-structured interviews. …”
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Impact of coronavirus disease 2019 on psoriatic arthritis: A multiregional observational study by Ranran Yao, Renge Liang, Jing Lu, Hongxia Li, Qiao Zhou, Yuhui Li, Liling Xu, Gong Cheng, Yuan Jia, Yin Su

“…Methods A total of 163 adult patients with PsA from 15 province‐level regions in China were enrolled in this multiregional observational study from January 14, 2023, to March 22, 2023. Data on patient demographics, COVID‐19 status, and disease characteristics were collected through a structured questionnaire survey. …”
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Type 2 gene expression signature in severe asthma associates with more advanced airway remodeling by Bogdan Jakiela, Karolina Górka, Iwona Gross‐Sondej, Sławomir Mikrut, Krzysztof Okoń, Piotr Sadowski, Anna Andrychiewicz, Hanna Plutecka, Tomasz Stachura, Grażyna Bochenek, Stanisława Bazan‐Socha, Krzysztof Sładek, Jerzy Soja

“…Severe asthma is linked to reduced ventilatory function due to airway structural changes. This study compared the extent of airway remodeling in different immunological endotypes of asthma. …”
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Exploring the relationship between intrinsic capacity and social participation in healthy ageing: Evidence from Singapore by Grace Cheong, William Tov, Robin Wai Munn Choo, Micah Tan, Lay Khoon Lau, Wee Shiong Lim, Yew Yoong Ding, Paulin Tay Straughan

“…We performed structural equation modelling to compare the direct and indirect effects (mediated by IADLs) of intrinsic capacity on social participation. …”
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Excessive body weight and its contributing factors in visually impaired patients in northwest Ethiopia, 2024 by Baye Ashenef, Bayu Wondimneh Yimenu, Enatnesh Essa Osman, Derese Sinamaw, Gelagey Baye, Zigale Hibstu Teffera, Mamaru Getinet Engida, Adane Adugna, Enyew Fenta Mengistu, Temesgen Baylie, Mohammed Jemal

“…An interviewer-administered structured questionnaire and physical assessments were used to gather data. …”
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Endothelial Damage in Sepsis: The Interplay of Coagulopathy, Capillary Leak, and Vasoplegia—A Physiopathological Study by Gianni Turcato, Arian Zaboli, Lucia Filippi, Alessandro Cipriano, Paolo Ferretto, Michael Maggi, Fabrizio Lucente, Massimo Marchetti, Lorenzo Ghiadoni, Christian J. Wiedermann

“…The Sepsis-Induced Coagulopathy (SIC) score, serum albumin (as a surrogate for capillary leak), and Total Peripheral Resistance Index (TPRI) (as a surrogate for vasoplegia) were assessed. Structural Equation Modeling (SEM) explored the relationship between variables, hypothesizing a common latent factor (endothelial damage). …”
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A cross-sectional study on depression and its associated factors among rural elderly in Chengalpattu District, Tamil Nadu by Ramesh Anshul, Ashokkumar Vikram, Sankar Karthik, Deepak Avinash KR, Mani Ezhilvanan, Chinnaian Sivagurunathan

“…A pre-tested, semi-structured interview schedule was used, including sociodemographic questions and the 30-item geriatric depression scale. …”
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THE ARTISTIC POTENTIAL OF CHORAL CONDUCTING IN CONTEMPORARY UKRAINE by Lyudmyla SHUMSKA, Yuliia PUCHKO-KOLESNYK, Lyudmyla KOSTENKO, Oleksandr VILA-BOTSMAN, Olha MARTYNOVSKA

“…As part of the methodological approach to the study, a comparative and structural analysis was applied, including the processing of statistical data on choral performances on the YouTube platform, as well as an analysis of the use of modern technologies in Ukrainian music institutions based on open sources. …”
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Acceptability of the Moyo device for intrapartum fetal heart rate monitoring at a referral hospital in Uganda: a qualitative study by Milton W. Musaba, Ritah Nantale, Julius N. Wandabwa, Agnes Napyo, Albert Ssesanga, Usaama Ssewankambo, Akello Eunice, Kenneth Mugabe, Brendah Nambozo, Faith Oguttu, John Stephen Obbo, Andrew D. Weeks, David Mukunya

“…Participants were purposively selected and interviewed using a semi-structured interview guide. The interviews were audio recorded and transcribed verbatim. …”
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