Conceptualizing the implementation of post-discharge malaria chemoprevention in Malawi using a co-design approach by Myness Kasanda Ndambo, Kristine Bærøe, Kamija Samuel Phiri, Isabel-Kazanga Chiumia, Inger Lise Teig, Bjarne Robberstad, Oddvar Martin Kaarbøe, Melf-Jakob Kühl, Jobiba Chinkhumba, Thandile Nkosi-Gondwe, Tinashe Alinafe Tizifa, Elisabeth Mamani-Mategula, Lumbani Munthali, Lucinda Manda-Taylor

“…Results The inductive analysis yielded four overarching themes from the data. These key themes are PDMC adaptability, trialability, implementability, and sustainability. …”
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Performance of GPT-4 for automated prostate biopsy decision-making based on mpMRI: a multi-center evidence study by Ming-Jun Shi, Zhi-Xiang Wang, Shuang-Kun Wang, Xuan-Hao Li, Yan-Lin Zhang, Ying Yan, Ran An, Li-Ning Dong, Lei Qiu, Tian Tian, Jia-Xin Liu, Hong-Chen Song, Ya-Fan Wang, Che Deng, Zi-Bing Cao, Hong-Yin Wang, Zheng Wang, Wei Wei, Jian Song, Jian Lu, Xuan Wei, Zhen-Chang Wang

“…GPT-4 generated structured reports with given prompts. The performance of GPT-4 was quantified using confusion matrices, and sensitivity, specificity, as well as area under the curve were calculated. …”
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A qualitative study on dietary behaviors and nutritional management needs of patients with active systemic lupus erythematosus (系统性红斑狼疮活动期患者饮食行为与营养管理需求的质性研究)... by SONG Weiting (宋炜婷), LI Yuwei (李雨蔚), QIAO Caicai (乔彩彩), WANG Sa (王飒), XUE Fei (薛菲), WANG Yuzhen (王玉珍), MIAO Huali (苗华丽)

“…Methods A descriptive study was conducted, involving semi-structured interviews with 10 patients with active SLE and 6 healthcare providers. …”
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Evidence based consensus statements for digital tools to address youth mental health literacy by Stephana Julia Moss, Sonia Siddiqui, Cristina Zuniga Chacon, Cynthia Sriskandarajah, Maia Stelfox, Ben Gaunce, Micaela Harley, Stacie Smith, Sofia B. Ahmed, Kathryn Birnie, Donna Halperin, Scott Halperin, Christine Hampson, Jia Hu, Laura Leppan, Angie Nickle, Kristine Russell, Andrea Soo, May Solis, Henry T. Stelfox, Sharon Straus, Perri R. Tutelman, Quincy Wiele, Kirsten M. Fiest, Nicole Racine, Jeanna Parsons Leigh

“…Phase II consisted of a modified Delphi consensus process to determine evidence-based consensus statements (N = 352 (13% youth) Round 1; N = 87 (33% youth) Round 2). Semi-structured focus groups in Phase III were conducted to refine the consensus statements (N = 16, 25% youth) and design the digital mental health literacy tool (N = 24, 33% youth). …”
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Lethal clinical outcome and chemotherapy and immunotherapy resistance in patients with urothelial carcinoma with MDM2 amplification or overexpression by Weijuan Zhang, Jiejie Xu, Hailong Liu, Yu Zhu, Zewei Wang, Han Zeng, Zhaopei Liu, Yuan Chang, Le Xu, Kaifeng Jin, Jingtong Xu, Xiaohe Su, Yawei Ding, Lingkai Zhang, Jiaxing Sun, Yuzhen Wu

“…In addition, UC with MDM2 amplification or overexpression was associated with an immuno-evasive contexture characterized by lower proportion of tertiary lymphoid structure infiltration, lower abundance of CD8+ T cells, IFN-γ+ cells, GZMB+ cells, and decreased expression of immune checkpoint molecules including programmed death-ligand 1 (PD-L1), programmed death-1 (PD-1) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4).Conclusions MDM2 amplification or overexpression defines a lethal subset of patients with UC with inferior prognosis and resistance to both platinum-based chemotherapy and immunotherapy irrespective of TP53/p53 status. …”
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A qualitative analysis on the awareness of noise pollution and occupational protection among staff members of the Central Sterile Supply Department (消毒供应中心工作人员对噪声污染的认知及职业防护质性分析)... by HUANG Xuanxuan (黄玄玄), FU Li (付立), SUN Ziwen (孙子文), YU Jiang (于江), ZHANG Shenhong (张沈弘), ZHANG Tianqiang (张天强)

“…Methods Through face-to-face and semi-structured interviews, 10 staff members from the Central Sterile Supply Department were interviewed in depth. …”
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Risk factors for low knowledge and negative attitudes among caregivers of children with autism spectrum disorder in Iraq: a multi-centre cross-sectional study by Hiba Qahttan Khaleel Al-Juhaishi, Hiba Qahttan Khaleel Al-Juhaishi, Osamah Abbas Jaber, Osamah Abbas Jaber, Faris Lami, Faris Lami, Shatha Mohammed Jasim, Shatha Mohammed Jasim, Nahid Dehghan Nayeri, Nahid Dehghan Nayeri, Mahdi Shafiee Sabet, Mahdi Shafiee Sabet, Ghaith Al-Gburi, Ghaith Al-Gburi

“…Before educational interventions can address these issues, local knowledge and attitudes must be assessed, including the identification of high-risk groups that require prioritisation.MethodsBetween February 17 and September 10, 2024, Al-Subtain Academy for Autism and Baghdad’s National Centre for Autism and Child Psychiatry conducted a cross-sectional study. Data was collected using a structured questionnaire developed based on the Autism Stigma and Knowledge Questionnaire (ASK-Q) and a review of previous studies. …”
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Recurrent Jetlets Associated with the Disappearance of a Satellite Spot by Liheng Yang, Xiaoli Yan, Jun Zhang, Zhike Xue, Zhe Xu, Jincheng Wang, Yijun Hou, Yian Zhou, Defang Kong, Roslan Umar, Xinsheng Zhang, Qiaoling Li, Liping Yang

“…The horizontal magnetic field of the satellite spot consistently exhibited a vortex structure throughout its evolution until it vanished. …”
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Molecular characteristic, evolution, and pathogenicity analysis of avian infectious bronchitis virus isolates associated with QX type in China by Yuanlu Lu, Yiran Zeng, Haowei Luo, Bingchen Qiao, Qi Meng, Zijian Dai, Na Chen, Lingcai Zhao, Xianchen Meng, Haitao Zhang, Jun Xia, Jihui Ping

“…Our data indicate antigenicity variances between QX isolates and QXL87 vaccine strains, potentially resulting in immune evasion occurrences. …”
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Systemic inflammation is an important risk factor and predictor of graft loss and mortality one year after kidney transplantation by Torbjørn F. Heldal, Torbjørn F. Heldal, Torbjørn F. Heldal, Anders Åsberg, Anders Åsberg, Anders Åsberg, Thor Ueland, Thor Ueland, Thor Ueland, Anna V. Reisæter, Anna V. Reisæter, Søren E. Pischke, Søren E. Pischke, Tom E. Mollnes, Tom E. Mollnes, Pål Aukrust, Pål Aukrust, Pål Aukrust, Pål Aukrust, Finn P. Reinholt, Anders Hartmann, Anders Hartmann, Kristian Heldal, Kristian Heldal, Kristian Heldal, Trond G. Jenssen, Trond G. Jenssen

“…BackgroundAn inflammatory environment following kidney transplantation is associated with increased risk of graft loss and mortality, however, evaluation of systemic inflammation is not implemented in structured risk assessment in kidney transplant recipients. …”
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Postnatal care could be the key to improving the continuum of care in maternal and child health in Ratanakiri, Cambodia. by Kimiyo Kikuchi, Junko Yasuoka, Keiko Nanishi, Ashir Ahmed, Yasunobu Nohara, Mariko Nishikitani, Fumihiko Yokota, Tetsuya Mizutani, Naoki Nakashima

“…Overall, 377 women were included, and data were collected via face-to-face interviews using a semi-structured questionnaire. …”
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Sources of uncertainty in DNA metabarcoding of whole communities: Implications for its use in biomonitoring by J. Iwan Jones, Amanda Arnold, Dominik Buchner, John F. Murphy, Jasmine N. Childress, Pedro Beja, Florian Altermatt, Kristian Meissner, Ian Adams, Meri Anderson, Yaisel J. Borrell, Andrew G. Briscoe, Kat Bruce, Cátia Chaves, Chris Conyers, Kristy Deiner, Vasco Elbrecht, Álvaro Fueyo, Tim Goodall, Javier Granero‐Castro, Cristina Hartmann‐Fatu, Eleanor Jones, Elvira Mächler, Filipa M. S. Martins, Sam McGreig, Lyndall Pereira‐da‐Conceicoa, James L. Pretty, Daniel S. Read, Ben Price, Florian Leese, Rosetta C. Blackman

“…However, the routine application of DNA‐based methods to monitor whole communities using a metabarcoding approach and derive ecosystem status continues to be limited. We undertook a structured experiment to assess factors influencing the precision and accuracy of molecular methods for freshwater macroinvertebrate community assessment. …”
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Exploring the impact of APOE ɛ4 on functional connectivity in Alzheimer’s disease across cognitive impairment levels by Kangli Dong, Wei Liang, Ting Hou, Zhijie Lu, Yixuan Hao, Chenrui Li, Yue Qiu, Nan Kong, Yan Cheng, Yaqi Wen, Wanyin Ma, Wenbin Zheng, Jitian Guan, Yan Lin, Kai Huang, Lu Zhang, Siya Chen, Xiangyuan Ma, Renhua Wu, Naili Wei

“…Studies have shown that APOE ɛ4 mediates the modulation of intrinsic functional brain networks in cognitively normal individuals and significantly disrupts the whole-brain topological structure in AD patients. However, how APOE ɛ4 regulates brain functional connectivity (FC) and consequently affects the levels of cognitive impairment in AD patients remains unknown. …”
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Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

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Possible Carbon Dioxide above the Thick Aerosols of GJ 1214 b by Everett Schlawin, Kazumasa Ohno, Taylor J. Bell, Matthew M. Murphy, Luis Welbanks, Thomas G. Beatty, Thomas P. Greene, Jonathan J. Fortney, Vivien Parmentier, Isaac R. Edelman, Samuel Gill, David R. Anderson, Peter J. Wheatley, Gregory W. Henry, Nishil Mehta, Laura Kreidberg, Marcia J. Rieke

“…Further modeling of the planet’s atmosphere, interior structure and origins will provide valuable insights about how sub-Neptunes like GJ 1214 b form and evolve.…”
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Nematodes exposed to furfural acetone exhibit a species-specific vacuolar H+-ATPase response by Wanli Cheng, Wei Dai, Wen Chen, Hua Xue, Zhengzheng Zhao, Zhengbing Jiang, Huanan Li, Jiashu Liu, Feng Huang, Minmin Cai, Longyu Zheng, Ziniu Yu, Donghai Peng, Jibin Zhang

“…And the Spearman analysis results illustrated that the differential nematicidal activity of FAc against various nematodes is attributed to variations in the sequence and structure of the receptor proteins VHA-12 and VHA-13 among different nematode species. …”
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Real-Time FTM-Based Victim Positioning System Using Heterogeneous Robots in Remote and Outdoor Scenarios by Juan Bravo-Arrabal, Carlos Simon Alvarez-Merino, Manuel Toscano-Moreno, Javier Seron-Barba, J. J. Fernandez-Lozano, Jose Antonio Gomez-Ruiz, Emil J. Khatib, Raquel Barco, Alfonso Garcia-Cerezo

“…A centralized Feedback Information System (FIS) processes real-time RTT data from the field, executes a multilateration algorithm, and provides live geolocation updates to SAR coordinators. …”
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Factors associated with knowledge, attitudes, and practices of mixed crop-livestock farmers on Crimean-Congo hemorrhagic fever (CCHF) and other zoonoses in Burkina Faso by Abdoul Kader Ilboudo, Michel Dione, Ard M. Nijhof, Martin H. Groschup, Ousmane Traoré, Guy S. Ilboudo, Zekiba Tarnagda, Madi Savadogo, Bernard Bett

“…Consenting participants aged six and above were randomly included, and a structured questionnaire that collected socio-economic data, knowledge, attitudes, and practices concerning CCHF and other zoonoses was administered. …”
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Associations of nutrient intake, dietary behaviours, and patterns with metabolic profiles and obesity measures: findings from a cross-sectional study in a southern Chinese populati... by Yifan Chen, Guanlin Chen, Yinglin Liang, Yinglin Liang, Haiyan Huang, Yefeng Cai, Xiaojia Ni

“…Demographic information, disease history, nutrient intake, and dietary behaviours were collected via face-to-face interviews using structured questionnaires. Metabolic profiles and obesity levels were assessed via clinical laboratory tests, physical examinations, and bioelectrical impedance analysis. …”
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Analysis of ROH Characteristics Across Generations in Grassland-Thoroughbred Horses and Identification of Loci Associated with Athletic Traits by Wenqi Ding, Wendian Gong, Tugeqin Bou, Lin Shi, Yanan Lin, Xiaoyuan Shi, Zheng Li, Huize Wu, Manglai Dugarjaviin, Dongyi Bai

“…Principal component analysis (PCA) and STRUCTURE revealed clear distinctions among the generations, with a notable overlap between CY and F3. …”
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