A comprehensive review on novel opportunities for Alzheimer therapy by targeting BIN1 by Trina Saha, Dipanjan Karati

“…Conclusion The most frequent BIN1 variants are found in non-coding regions immediately upstream of the gene, and it is thus likely that their impact is regulatory and not structural. The variants can influence the levels of BIN1 or splicing between isoforms, especially the distribution of isoforms. …”
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Molecular Determinants for the Binding of the Highly Infectious SARS-CoV-2 Omicron (BA.1) Variant to the Human ACE2 Receptor by Majed S. Aljohani, Pawan Bhatta, Xiche Hu

“…Additionally, allosteric effects improve the contributions of non-mutated residues (notably A475, Y453, and F486) via structural realignment and novel hydrogen bonding with ACE2 residues such as S19, leading to an overall increase in the electrostatic and π-system interaction energy. …”
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Diversity and equity in medical education over the past decade: applications, matriculations, and the growing gaps by Gang Lv, Xiangxiang Jiang, Jordan Franklin, Minghui Li, Jing Yuan, Z. Kevin Lu

“…Methods This study used data from the Association of American Medical Colleges from 2015 to 2024. …”
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Association of workplace support for health with occupational health literacy and illness avoidance: moderated mediation by functioning through a salutogenic lens by Nestor Asiamah, Isaac Aidoo, Etornam Doamekpor, Emelia Sarpong, Emelia Danquah, Cosmos Yarfi, Eric Eku, Usman Yaw Baidoo, Christiana Afriyie Manu, Rita Sarkodie Baffoe

“…., WSH, OHL, functioning, and illness avoidance) were measured with Likert-type scales adopted in whole from the literature. Data were analysed with Hayes’ Process Model through structural equation modelling. …”
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PSYCHOLOGICAL READINESS OF SECONDARY VOCATIONAL EDUCATION TEACHERS FOR MASTERING NEW ACTIVITIES IN THE CONTEXT OF PROFESSIONAL REORIENTATION by I. I. Khasanova, S. S. Kotova

“…The functionality of this technology, its tasks, structural components, possible methods and estimated effects of its implementation in practice of the SPE (Secondary Professional Education) system are noted.Practical significance. …”
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Enhancing Accessibility in Philippine Public Bus Systems: Addressing the Needs of Persons with Disabilities by Ma. Janice J. Gumasing, Timothy Ray P. Del Castillo, Antoine Gabriel L. Palermo, Janred Thien G. Tabino, Josiah T. Gatchalian

“…Structural equation modeling (SEM) was used to analyze the hypothesized relationships between these variables, passenger satisfaction, and intention to reuse public transport. …”
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Viral activity in lake analogs of anoxic early Earth oceans by Natascha S. Varona, Bailey A. Wallace, Alice Bosco-Santos, Julianna Mullinax, Alexandra K. Stiffler, Molly D. O’Beirne, Josh Ford, James M. Fulton, Josef P. Werne, William P. Gilhooly, Cynthia B. Silveira

“…This suggests that viral lysis may contribute less to bacterial community structuring in these high-density microbial plates. …”
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A descriptive analysis of significant factors influencing the behavioral intention to adopt robot kiosks/service robots in service stores: Integrating the UTAUT and higher-order SE... by Dioseph Andre F. Anduyo, Ardvin Kester S. Ong, Maela Madel L. Cahigas, Ma. Janice J. Gumasing, Dhonn Q. Tomas

“…Utilizing the integrated Unified Theory of Acceptance and Use of Technology (UTAUT) model and SERVQUAL 5 dimensions higher-ordered structural equation modeling approach, the study found that tangibles (β: 0.807), empathy (β: 0.782), responsiveness (β: 0.765), assurance (β: 0.711), reliability (β: 0.646), and behavioral intention (β: 0.104) significantly affected customer satisfaction. …”
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The Chain Mediating Effect of Health Literacy and Self-Care Ability on the Relationship Between Dysmenorrhea Symptoms and Negative Emotions Among Chinese Female College Students by Luo Y, Liu D, Sun G, Lu Y, Fang M, Zhang Y, Xu C, Bai G, Chen C

“…Multiple linear regression analysis was conducted to analyze the effects of variables with statistically significant differences (P < 0.05) identified through one-way ANOVA, independent sample t-tests, and correlation analysis on psychological levels. Structural Equation Modeling (SEM) was used to explore mediating effects.Results: This study shows that dysmenorrhea symptoms, health literacy, self-care ability, and negative emotions are significantly correlated. …”
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Airway epithelial cell-specific deletion of EGFR modulates mucoinflammatory features of cystic fibrosis-like lung disease in mice by Ishita Choudhary, Kshitiz Paudel, Rahul Kumar, Amit Sharma, Sonika Patial, Yogesh Saini

“…The airway epithelial cell-specific EGFR-deficient wild-type (WT) mice did not exhibit any obvious structural and functional defects in the lungs. The deletion of EGFR in airway epithelial cells in Tg+ mice, however, resulted in increased recruitment of neutrophils and macrophages into the lung airspaces, which was accompanied by significantly increased bronchoalveolar lavage fluid (BALF) levels of inflammatory mediators, including KC, G-CSF, MIP-2, MIP-1α, TNF-α, and MIP-1β. …”
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Formation of Adaptive and Integrative Potential of Children with Mental Retardation in Artistic and Creative Activities by O. A. Denisova, T. V. Gudina, I. A. Bukina, O. L. Lekhanova, A. V. Selina

“…The criteria and qualitative characteristics of the levels of formation of this potential are highlighted. Three of its structural components – cognitive, emotional and behavioural – are identified, which are proposed to be developed through artistic and creative activities with close cooperation of specialists of the school support service, parents and teachers of additional education. …”
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The Neurogenic Effects of Pasak bumi (Eurycoma longifolia Jack) and Seluang Fish (Rasbora spp.) in Malnutrition-Induced Rat by Didik Dwi Sanyoto, Triawanti Triawanti, Meitria Syahadatina Noor, Dimas Ikhsan Airlangga

“…Abstract Early developmental malnutrition exerts adverse effects on the structural, neurochemical, and neurophysiological maturation of cerebral cells by disrupting the process of neurogenesis. …”
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Lower extremity functional performance tests and their measurement properties in athletes: a systematic review and narrative synthesis by Alison Rushton, Nicola R Heneghan, Lee Herrington, James Martin, Rosalyn Cooke, Andy Soundy

“…Reliability (n=14), measurement error (n=11), structural validity/internal consistency (n=2), criterion validity (n=11), construct validity (n=5) and responsiveness (n=1) were assessed. …”
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Carotid intima thickness and elasticity combined with MHR predicting the severity of coronary artery stenosis in patients with premature coronary artery disease by Chenjing Xu, Ming Wu, Xijun Zhang, Kaikai Shen, Yanyan Guo, Jianjun Yuan, Haohui Zhu

“…Abstract Background Carotid intima thickness (CIT) and hardness coefficient (HC) are sensitive indicators of structural and functional changes in the carotid arteries in the subclinical stage of atherosclerosis. …”
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The relationship between digital literacy and innovative behavior among Chinese medical students: the chain mediating roles of diversity experience and creative self-efficacy by Juan Wu, Qilin Zhang, Xiaomin Gan, Xuefang Liu, Jiuying Hu, Yalin Wang

“…SPSS 25.0 and AMOS 24.0 software were used, and the structural equation model was established to statistically analyze the data. …”
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Does a growth mindset curb anxiety among Chinese medical students? Validation based on propensity score matching by Xiao-Jing Yang, Yu-Tian Gan, Zi-Jiao Wang, Jian-Ye Wang, Xiao-Jian Duan, Xing Ma, Tao Sun, De-Pin Cao, Shu-E Zhang

“…Educators should foster the cultivation of growth mindset in medical students through multidimensional interventions involving cognitive scaffolding, behavioral reinforcement, and environmental structuring, which consequently enhances their psychological well-being. …”
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A meta-analysis of MHC diversity in Pan troglodytes verus by Christelle Vangenot, Alicia Sanchez‑Mazas

“…The MHC region has been subdivided in different classes according to the functional and structural characteristics of the genes. For Class I, chimpanzees possess single A, B and C loci orthologous to the human MHC loci A, B and C, respectively. …”
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Modern Pushkin Studies at the International Congress of Teachers and Lecturers of Russian Language and Russian Literature, Dedicated to the 225th Anniversary of the Birth of A.S. P... by Tatiana V. Kortava, Larisa A. Dunaeva, Victoria G. Moiseeva

“…The methodological foundation of the article is the interdisciplinary approach and the structural and functional analysis of a set of problems associated with the study and teaching of Pushkin’s work in the modern cultural and historical context. …”
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Knowledge, attitudes, and practices of epilepsy patients regarding the ketogenic diet therapy: A cross‐sectional study by Xiuping Zhang, Meizhen Sun, Guofang Xue, Yongxiong Zhao, Taotao Du, Xueying Guan, Yong Xu

“…Multivariate analysis revealed that the attitude score (OR = 1.443, 95% CI: [1.296–1.607], p < 0.001) and an epilepsy duration of 5–10 years (OR = 3.086, 95% CI: [1.716–5.548], p < 0.001) were independently associated with positive practice. Additionally, Structural Equation Modeling indicated that knowledge (β = 0.034, p = 0.012) and attitude (β = 0.583, p = 0.010) directly influenced practice, while knowledge also directly affected attitude (β = 0.565, p = 0.013), with an indirect effect on practice through attitude (β = 0.329, p = 0.009). …”
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Uncovering the factors of financial well-being: the role of self-control, self-efficacy, and financial hardship by Jorge Hernandez-Perez, Salvador Cruz Rambaud

“…To test the hypotheses concerning the direct and indirect relationships between self-regulation factors and financial well-being, partial least squares structural equation modeling (PLS-SEM) was employed. …”
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