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51081
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51082
A novel missense pathogenic variant c.9455T > G (p.L3152R) in CDH23 underlies autosomal recessive non-syndromic hearing loss
Published 2025-06-01“…This study aimed to identify the genetic cause of autosomal recessive non-syndromic hearing loss (ARNSHL) in a large Iranian family using next-generation sequencing and structural bioinformatics. Methods After a comprehensive clinical evaluation of a large family with a history of HL the GJB2 gene was sequenced, and 7 loci were screened through genetic linkage analysis. …”
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51083
The smart senior care demand in China in the context of active ageing: a qualitative study with multiple perspectives
Published 2025-04-01“…This study aimed to explore the needs and expectations of relevant stakeholders of smart senior care in China in the context of active aging.MethodsThis is a qualitative descriptive study, in which 21 semi-structured interviews were conducted between October 2021 and March 2022. …”
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51084
Towards a net-zero healthcare system in Kenya: Stakeholder perspectives on opportunities, challenges and priorities
Published 2025-03-01“…Methods: This study employs qualitative methods, including 21 semi-structured interviews with key stakeholders and a Delphi consensus process, to explore stakeholder perspectives on Kenya's journey to a net-zero healthcare system. …”
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51085
Cognitive symptoms in schizophrenia: an analysis of awareness, assessment, and management practices among psychiatrists and primary care physicians
Published 2025-05-01“…In addition, further qualitative data were collected through individual semi-structured telephone interviews. …”
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51086
Aligning the principles and practice of research integrity and research fairness in global health: a mixed-methods study
Published 2024-03-01“…Despite extensive academic discussions, empirical data on these aspects, especially in the context of global health, remain limited.Methods To address this gap, we conducted a mixed-methods study focusing on research integrity and fairness. …”
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51087
Culinary connections: The mediating role of customer brand co-creation behavior in gastronomic and revisit intentions
Published 2025-01-01“…This study investigates the mediating role of customer brand co-creation behavior in the effect of gastronomic experience on revisit intention among Generation Z café visitors in Bali, Indonesia. Data were collected from 250 respondents via an online survey and analyzed using Partial Least Squares Structural Equation Modeling. …”
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51088
Longitudinal study of foot-and-mouth disease virus in Northern Nigeria: implications for the roles of small ruminants and environmental contamination in endemic settings
Published 2025-04-01“…The force of infection estimated from age-seroprevalence data for each household was significantly lower in goats compared with both cattle or sheep. …”
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51089
Technology Anxiety in Virtual Reality Adoption: Examining the Impact of Age, Past Experience, and Cybersickness
Published 2025-01-01“…Using an extended Technology Acceptance Model (TAM), the research integrates age and past use as antecedents of TA and evaluates their influence on perceived ease of use (PEoU), perceived enjoyment (PENJ), and user attitudes. Data from 206 participants were analysed using Partial Least Squares Structural Equation Modelling (PLS-SEM) following a VR pilgrimage experience. …”
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51090
Exploring the Relationship Between Excessive Social Media Use and Eating Disorders Among Young Adults: Evidence From a Bangladesh‐Based Cross‐Sectional Study
Published 2025-05-01“…Methods We conducted an online‐based cross‐sectional study among 550 young adults aged 18 to 27 in Bangladesh. A structured questionnaire was used to obtain the survey data. …”
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51091
A multi-species corridor between the Andean Amazonian and Amazon floodplain landscapes: prioritizing ecological connectivity areas for jaguar and threatened ungulates in the north-...
Published 2025-04-01“…To address this gap, we utilized occurrence data for focal species including the jaguar, lowland tapir, and collared peccary. …”
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51092
Wind speed forecasting approach using conformal prediction and feature importance selection
Published 2025-07-01“…Furthermore, a Bayesian Optimization with Tree-structured Parzen Estimators (BO-TPE) will be used to tune the hyperparameters of the models. …”
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51093
Peer support and online cognitive behavioural therapy for substance use concerns: protocol for a randomised controlled trial
Published 2022-12-01“…Results will help to optimise the effectiveness of structured online substance use interventions provided as an adjunct to standard care in hospital-based treatment programmes. …”
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51094
Integrative analysis of saliva-derived exosomal proteome and lipidome for the diagnosis of esophageal squamous cell carcinoma
Published 2025-08-01“…The proteomic characteristics of ESCC were primarily manifested in immune responses, disruption of tissue structural homeostasis, and enhanced antifungal and antimicrobial humoral immune responses. …”
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51095
An Overview of Treatment in Pediatric Bladder-bowel Dysfunction: A Single-Center Experience
Published 2025-08-01“…Objective: This study aimed to evaluate the clinical characteristics, treatment responses, and outcomes of pediatric patients diagnosed with bladder-bowel dysfunction, highlighting a structured management approach including urotherapy, pharmacotherapy, and rehabilitation techniques. …”
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51096
Optimized enrichment of murine blood–brain barrier vessels with a critical focus on network hierarchy in post-collection analysis
Published 2025-05-01“…Positioned between upstream arteries and downstream veins, these microvessels have unique structural features, such as the absence of vascular smooth muscle cells (vSMCs) and a relatively thin basement membrane, to facilitate highly efficient yet selective exchange between the circulation and the brain interstitium. …”
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51097
Lessons learned from the COVID-19 pandemic: opportunities and challenges to leverage investments in HIV, tuberculosis and malaria for pandemic preparedness and response
Published 2025-04-01“…This manuscript systematically documents how these programmes were used in response to understand both the barriers and facilitators encountered in the process.Methods From March through August 2023, we conducted 72 structured interviews with staff in 13 countries who played central roles in the response. …”
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51098
Addressing System Challenges in Mental Health Services Research for Youth in the Child Welfare System: Insights From the Foster Care Family Navigator Trial
Published 2025-03-01“…Systems‐level challenges that impacted proposed research trial design and data collection included: (1) Limited system staff time and compensation processes; (2) Staff training and knowledge; and (3) System disruptions. …”
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51099
A φSa3int (NM3) Prophage Domestication in Staphylococcus aureus Leads to Increased Virulence Through Human Immune Evasion
Published 2025-08-01“…Further, φSa3int prophage domestication led to reduced phagocytosis implying φSa3int prophage mediates escape of S. aureus from human innate immunity. Our data further show that in addition to adding novel prophage‐encoded virulence, φSa3int prophage domestication also affects the expression of non‐prophage (bacterial) genes and suppresses expression of structural proteins of resident prophages. …”
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51100
Impact of gas flaring on acute respiratory distress among pregnant women and newborn babies in Delta State Central Senatorial District, Nigeria
Published 2024-12-01“…Data were statistically analysed with the use of SPSS. …”
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