Improving regional care in the last year of life by setting up a pragmatic evidence-based Plan–Do–Study–Act cycle: results from a cross-sectional survey by Lena Ansmann, Holger Pfaff, Ingrid Schubert, Ludwig Kuntz, Stephanie Stock, Sheila Payne, Nadine Scholten, Ute Karbach, Stefanie Hamacher, Raymond Voltz, Christian Albus, Frank Jessen, Christian Rietz, Frank Schulz-Nieswandt, Julia Strupp, Gloria Dust, Nicolas Schippel

“…Objectives To set up a pragmatic Plan–Do–Study–Act cycle by analysing patient experiences and determinants of satisfaction with care in the last year of life.Design Cross-sectional postbereavement survey.Setting Regional health services research and development structure representing all health and social care providers involved in the last year of life in Cologne, a city with 1 million inhabitants in Germany.Participants 351 bereaved relatives of adult decedents, representative for age and gender, accidental and suspicious deaths excluded.Results For the majority (89%) of patients, home was the main place of care during their last year of life. …”
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Trauma systems: a global comparison by Theodore Miclau, MD, Zsolt J. Balogh, MD, PhD, Katherine R. Miclau, BA, Brian Bernstein, MD, Kodi Edson Kojima, MD, PhD, Taketo Kurozumi, MD, PhD, Ross K. Leighton, MD, PhD, Douglas W. Lundy, MD, MBA, Guy Putzeys, MD, Inger B. Schipper, MD, PhD, Wim Vandesande, MD, Marcos de Camargo Leonhardt, MD, MSc, Maria Adelaide Miranda Goncalves, MD, Guilherme Pelosini Gaiarsa, MD, MSc, Hans-Christoph Pape, MD

“…Trauma systems across countries vary significantly in the structure and regulation of trauma care, injury patterns, national data collection, and accessibility, reflecting diverse demographics and healthcare infrastructures. …”
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Diagnosis, evaluation and management of osteoporosis in chronic kidney disease: navigating treatment approaches – Indian consensus statement by Vijay Kher, Rajkumar Sharma, Georgi Abraham, Bharat Shah, Sishir Gang, Sanjeev Gulati, Manisha Sahay, Jatin Kothari, Anil Kumar BT, Raja Ramachandran, Sanjay Kalra, Rakesh Kumar Sahay, Om Lakhani, Jay Kumar Sharma, Deepak Bunger, Thomas L. Nickolas

“…Given the lack of robust clinical trial data and a notable knowledge gap exists among nephrologists regarding an optimal management in this population, an expert consensus is crucial for developing tailored management strategies. …”
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High prevalence of fecal carriage of extended-spectrum beta-lactamase producing Enterobacterales among patients with urinary tract infections in rural Tanzania by Magreth Erick Macha, Magreth Erick Macha, Magreth Erick Macha, Weihong Qi, Salome N. Seiffert, Anja Bösch, Philipp Kohler, Honorathy Msami Urassa, Sabine Haller, Erin West, Maja Weisser Rohacek, Maja Weisser Rohacek, Maja Weisser Rohacek, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury, Baharak Babouee Flury

“…Francis Regional Referral Hospital, Ifakara, Tanzania, from October 2021 to August 2023, involving 326 UTI patients. Demographic data and resistance risk factors were collected via structured questionnaires. …”
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The OsZHD1 and OsZHD2, Two Zinc Finger Homeobox Transcription Factor, Redundantly Control Grain Size by Influencing Cell Proliferation in Rice by Mingliang Guo, Chun Zheng, Chao Shi, Xiaozhuan Lu, Zeyuan She, Shuyu Jiang, Dagang Tian, Yuan Qin

“…Abstract Grain size is vital determinant for grain yield and quality, which specified by its three-dimensional structure of seeds (length, width and thickness). The ZINC FINGER-HOMEODOMAIN (ZHD) proteins play critical roles in plant growth and development. …”
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Shifts in the rhizosphere microbiome and exudation profile of avocado (Persea americana Mill.) during infection by Phytophthora cinnamomi and in presence of a biocontrol bacterial... by Frédérique Reverchon, Mariel García-Meléndez, Edgar Guevara-Avendaño, Oscar Mora-Chávez, Itzel A. Solís-García, Wesley Dáttilo, José A. Guererro-Analco, Alfonso Méndez-Bravo, Juan L. Monribot-Villanueva, Violeta Patiño-Conde, Fernando Pineda-García, Eria A. Rebollar

“…The dysbiosis (disturbance of the microbiome structure of healthy plants) caused by these pathogens, combined with the recruitment of beneficial microorganisms by the diseased plant, may cause shifts in the rhizosphere microbiome during the infection process. …”
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Effector Pt31812 from Puccinia triticina acts as avirulence factor for Lr42-mediated resistance in wheat by Jianyuan Li, Jianyuan Li, Jiali Li, Jie Wei, Jie Wei, Lin Li, Yue Qi, Yue Qi, Yue Zhang, Yue Zhang, Wenxiang Yang, Qian-Hua Shen

“…In the study, Pt31812 was cloned by PCR, and the expression pattern and structure were analyzed by qRT-PCR and online softwares. …”
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Serological evaluation of Crimean-Congo Hemorrhagic fever in humans with High-Risk professional exposure and in residual sera collected in 2022-2023 across Corsica (France) by Paloma Kiwan, Morena Gasparine, Dorine Decarreaux, Lisandru Capai, Shirley Masse, Miša Korva, Tatjana Avšič-Županc, Jean Canarelli, Marie-Helene Simeoni, Xavier de Lamballerie, Remi Charrel, Alessandra Falchi

“…Sociodemographic and epidemiological data were collected using a structured questionnaire in the high-risk group. …”
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Risk Factors and Prognostic Implications of Tumor‐Related Epilepsy in Diffuse Glioma Patients: A Real‐World Multicenter Study by Yao Xiao, Zhuang Nie, Jinsha Huang, Jie Zhao, Chengjun Dong, Yan Zou, Zikai Li, Bingqing Yan, Yue Hu, Fan Yang, Jong Woo Lee, Alexander P. Lin, Steven Tobochnik, Min Zhou, Ziqiao Lei

“…Multivariate analysis identified age as the only significant independent correlate of TRE in the OD/AC group (OR = 0.961; p = 0.004), while the absence of deep structure involvement was independently associated with TRE in the NOS/NEC and HGG groups. …”
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Do neonatal intensive care unit (NICU) health workers know about retinopathy of prematurity (ROP)? A qualitative study at a Regional Referral Hospital in Uganda by Henry Muwonge, Innocent Ayesiga, Primrose Magala, Tom Didimus Ediamu, Hana El Diwany, Ian LY Yeung, Alex Wasomoka, Phillip Musoke, Elias Musiime, Abraham Tumwesigye, Pius Atwau, Noreen Atwijukire, Iddi Ndyabawe, Anne Mpaire Musika, Himanshu I Patel, Aeesha NJ Malik, Ibrahim Bwaga, Sheba Gitta Nakacubo

“…We recommend developing a formal training structure and syllabus for ROP screening. The training can enhance task shifting among health workers in areas without specialised health workers. …”
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A 1.8 m Class Pathfinder Raman LIDAR for the Northern Site of the Cherenkov Telescope Array Observatory—Performance by Pedro José Bauzá-Ruiz, Oscar Blanch, Paolo G. Calisse, Anna Campoy-Ordaz, Sidika Merve Çolak, Michele Doro, Lluis Font, Markus Gaug, Roger Grau, Darko Kolar, Camilla Maggio, Manel Martinez, Samo Stanič, Santiago Ubach, Marko Zavrtanik, Miha Živec

“…The results show that the pBRL can provide valuable scientific results on aerosol characteristics and structure, although not all performance requirements could be validated under the conditions found at the two test sites. …”
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Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling by Jialu Shi, Wenjun Mao, Yuqing Song, Yuxin Wang, Lili Zhang, Yan Xu, Huiwen Gu, Siyu Yao, Yuanhang Yao, Zhifeng Liu, Vijaya Raghavan, Jin Wang

“…However, butyrate counteracted this loop by restoring microbiota structure and suppressing reactive oxygen species (ROS)/Notch cascades. …”
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Identification, Characterization, Expression Profiling and Functional Analysis of Tobacco <i>CalS</i> Gene Family by Hong Wang, He Meng, Xiaohan Qi, Yi Pan, Bailu Ji, Liuying Wen, Yanjun Zan, Huan Si, Yuanying Wang, Dan Liu, Aiguo Yang, Zhengwen Liu, Lirui Cheng

“…A comprehensive analysis of their physicochemical properties, gene structure, and evolutionary history highlighted their evolutionary conservation. …”
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Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort... by Edgar Wiebe, Elisa Celine Schilling, Dörte Huscher, Andriko Palmowski, Zhivana Boyadzhieva, Sandra Hermann, Burkhard Muche, Mirella Lopez Picazo, Gerhard Krönke, Falk Hiepe, Tobias Alexander, Frank Buttgereit

“…Our findings suggest that 3D bone structure analysis may be helpful in discriminating past vertebral fractures. …”
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Perceived effectiveness and recommendations from a childbirth quality assurance and improvement programme in India’s private sector: a qualitative evaluation using the RE-AIM frame... by Katherine Semrau, Meghna Desai, Lauren Spigel, Somesh Kumar, Megan Marx Delaney, Lauren Bobanski, Suranjeen Pallipamula, Natalie Henrich, Tapas Sadasivan Nair, Hema Divakar, Rajat Chabba, Shweta Jindal, Gulnoza Usmanova, Sukanya Dutta, Aarushi Gupta, Sucheta Kinjawadekar, Priti Kumar, Priyanka Kumari, Prerna Mukharya, Hrishikesh Pai, Ameya Purandare, Pompy Sridhar

“…We aimed to understand participants’ motivations for joining or not joining, the perceived value of Manyata and recommendations for sustainment and scale.Methods We aimed to sample 238 Manyata participants for semi-structured, in-depth interviews between February and July 2021. …”
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COVID-19 vaccine uptake, barriers and associated factors among healthcare workers in Malawi by Clara Sambani, Tonny Muwonge, Liness Chinyamunyamu, Amon Dembo, Mosoka P. Fallah, Victor Chikwapulo, Mavuto Thomas, Charity Gondwe, Regina Mankhamba, Leah Mbabazi, Suzan Nakasendwa, Rodgers R. Ayebare, Collins Mitambo, Matthew Kagoli, Dzinkambani Kambalame, Clement Seven, Tadala Mwale, Edna Mandala, Abigail Kazembe, McWilliam Kalua, Senga Sembuche, Elizabeth Gonese, Tamrat Shaweno, Nebiyu Dereje, Evelyn C. Banda, Tajudeen Raji, Mitch Matoga

“…Data were managed in REDCap and analysed using STATA version 14. …”
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Clinical effectiveness of mindfulness-based music therapy on improving emotional regulation in blind older women: A randomized controlled trial by Sunny H.W. Chan, Meryl Y.C. Cheung, Armstrong T.S. Chiu, Mimi H.T. Leung, Michael C.C. Kuo, Donald Y.C. Yip, Carole C.Y. Hui, Sally W.I. Kam, King Yeung, Doreen S.P. Mui, Shu-Mei Wang, Calvin C.K. Yip

“…Background: This study aimed to investigate clinical effectiveness of a structured eight-week mindfulness-based music therapy (MBMT) program on improving mood regulation in older women with blindness. …”
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Overexpression of Egr1 Transcription Regulator Contributes to Schwann Cell Differentiation Defects in Neural Crest-Specific <i>Adar1</i> Knockout Mice by Lisa Zerad, Nadjet Gacem, Fanny Gayda, Lucie Day, Ketty Sinigaglia, Laurence Richard, Melanie Parisot, Nicolas Cagnard, Stephane Mathis, Christine Bole-Feysot, Mary A. O’Connell, Veronique Pingault, Emilie Dambroise, Liam P. Keegan, Jean Michel Vallat, Nadege Bondurand

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A preliminary study of the pathological characteristics of the internal orifice and the local mucosal microbial community in complex anal fistula by Zhu Jingyi, Zhang Ling, He Li, Zhang Jun, Mei Zubing, Wang Zhenyi, Chen Qiyi, Wang Qingming

“…[Objectives] To observe the histological morphology and Mucoprotein 2 (MUC2) expression in the internal orifice of complex anal fistula, as well as to compare the difference of the composition and structure of the microbial community in the mucosal tissue of the internal orifice of patients with complex anal fistula with the anal sinus mucosa of the healthy population. …”
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Humic acid from leonardite for cadmium adsorption and potential applications by MENG Fande, YUAN Guodong, WEI Jing, BI Dongxue, WANG Hailong, LIU Xingyuan

“…In contrast, Leo-HA is beneficial to soil structure and soil quality, as well as safe to handle in the field. …”
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