Endothelial soluble epoxide hydrolase links polyunsaturated fatty acid metabolism to oxidative stress and atherosclerosis progression by Minghua Cao, Mengqing Li, Xixuan Li, Yuanyuan Li, Yunyun Chen, Maria-Kyriaki Drekolia, Xiang Cheng, Fredy Delgado Lagos, Sofia-Iris Bibli, Jiong Hu

“…Such inhibition, resulted in a lowering of the mitochondrial membrane potential and subsequent excessive mitochondrial reactive oxygen species production and disrupted mitochondrial structure. Heightened mitochondrial redox generation ultimately led to TGFβ activation and the subsequent stimulation of an athroprone and pro-inflammatory endothelial transcriptional programme. …”
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Reconciling species diversity in a tropical plant clade (Canarium, Burseraceae). by Sarah Federman, Michael J Donoghue, Douglas C Daly, Deren A R Eaton

“…We recognize at least six distinct clades based on genetic structure and species delimitation analyses that correspond clearly with geographic and discrete morphological differences. …”
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Effects of vaping on physical and mental health in at-risk populations (VAPE): mixed-methods study of motivations for and perspectives on vaping in patients with opioid use disorde... by Alessia D’Elia, Balpreet Panesar, Nitika Sanger, Laura O’Neill, Tea Rosic, Leonora Regenstreif, Kevin Park, Claire de Oliveira, David C. Marsh, Luciano Minuzzi, Lehana Thabane, Zainab Samaan

“…An inductive data-driven approach was employed to characterise perspectives on vaping. …”
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Using Natural Language Processing to Explore Patient Perspectives on AI Avatars in Support Materials for Patients With Breast Cancer: Survey Study by Eleanor Cheese, Raouef Ahmed Bichoo, Kartikae Grover, Dorin Dumitru, Alexandros Zenonos, Joanne Groark, Douglas Gibson, Rebecca Pope

“…We applied and evaluated different NLP machine learning techniques to draw insights from these unstructured data, namely sentiment analysis, topic modeling, summarization, and term frequency–inverse document frequency word clouds. …”
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Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
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Effect of low-moderate intensity traditional Chinese exercises combined with acupuncture on patients with stable chronic obstructive pulmonary disease: study protocol for a randomi... by Hongxia Duan, Yidie Bao, Linhong Jiang, Peijun Li, Yingqi Wang, Yuchen He, Xinliao Deng, Weibing Wu, Wei Zhang, Xiaodan Liu, Xiaodan Liu

“…Secondary outcomes will include lung function, degree of dyspnea, diaphragmatic function, respiratory muscle strength, skeletal muscle structure, skeletal muscle function, psychological states, and quality of life. …”
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CORRECTION OF HYPODINAMY AS A FACTOR OF THE RISK OF OBESITY DEVELOPMENT IN FIRE-RESCUERS by E. V. BURDYUKOVA, A. N. ARKHANGELSKAYA, S. N. ALEKSEENKO, I. A. YAKIREVICH, E. A. DMITRIEVA, O. P. KARAZHELYASKOV, M. V. IVKINA, K. G. GUREVICH

“…A questionnaire was conducted to identify hypodynamia (according to the IPAQ questionnaire) and the nutrition structure (according to the questionnaire on the food label literacy questionnaire, past). …”
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Artificial Intelligence in Breast Cancer Diagnosis and Treatment: Advances in Imaging, Pathology, and Personalized Care by Petar Uchikov, Usman Khalid, Granit Harris Dedaj-Salad, Dibya Ghale, Harney Rajadurai, Maria Kraeva, Krasimir Kraev, Bozhidar Hristov, Mladen Doykov, Vanya Mitova, Maria Bozhkova, Stoyan Markov, Pavel Stanchev

“…However, challenges include data variability, ethical concerns, and real-world validation. …”
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Development and preliminary validation of a Chinese Physical Activity Parenting Practices Scale (3–6 years) by Ren Na, Ying Liang, Haiyue Zhang, Zhe Yang, Nan Li, Wei Zhang, Han Tang, Weiliang Ye, Linyuan Zhang, Xun Jiang, Lei Shang

“…We ultimately developed a formal version of the Chinese Physical Activity Parenting Practices Scale (CPAPPS) using the remaining 30 items. We examined the structure of the scale using factor analysis and evaluated its reliability, validity, and discriminant ability using data from 899 parents of children aged 3–6 years.ResultsThe CPAPPS includes 30 items in 6 dimensions scored on a 5-point Likert scale. …”
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Theory and engineering practice of coal-water coordinated mining based on constraints of formation bearing capacity by Zhenzhong PANG, Yifan ZENG, Keyao HAN, Qiang WU, Shouqiang LIU, Zhaolai HUA, Gangyi ZHAO, Shuai ZHANG, Huxiong YANG, Xuejun WANG, Feifan LI

“…Dominant factors controlling the formation structure damage were identified using the theory of simply supported beams and hydrogeological theories. …”
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Comparative genomics and phylogenetic analysis of mitochondrial genomes of Neocinnamomum by Wen Zhu, Di Zhang, Wenbin Xu, Yi Gan, Jiepeng Huang, Yanyu Liu, Yunhong Tan, Yu Song, Peiyao Xin

“…We successfully assembled the mitogenome of N. delavayi, which is 778,066 bp in size and exhibits a single circular structure. The analysis identified 659 dispersed repeats, 211 simple sequence repeats (SSRs), and 30 tandem repeats within the mitogenome. …”
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Generation of 1 km high resolution Standardized precipitation evapotranspiration Index for drought monitoring over China using Google Earth Engine by Yile He, Youping Xie, Junchen Liu, Zengyun Hu, Jun Liu, Yuhua Cheng, Lei Zhang, Zhihui Wang, Man Li

“…However, limited by its spatial resolution of 0.5 degrees, it is difficult to describe the local spatio-temporal structure of drought. How to improve its spatial resolution while maintaining spatio-temporal consistency is one of the current research hotspots. …”
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Understanding community pharmacists’ intentions to report adverse drug reactions in Saudi Arabia: a theory of planned behavior analysis by Fahad T. Alsulami, Yousef Saeed Alqarni, Wadia Saad Alruqayb, Mohammed S. Alharthi, Mohammad S. Alzahrani, Majed A. Algarni, Musaad M. Althobaiti, Saad Mohammed Almalki, Nawaf Abid Altowarqi, Hussain Ali Mathkur, Anas Muslih Althumali, Ayman Mohammed Alharthi, Haifa Abdulrahman Fadil, Adel A. Altowairqi, Mubarak S. Alharthi

“…Strategies such as structured training, institutional support, and promoting moral responsibility may bridge the gap between awareness and actual reporting practices among community pharmacists in Saudi Arabia.…”
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Characteristics of the gut virome in patients with premalignant colorectal adenoma by Pan Zhang, Xiaofeng Tuo, Jiong Jiang, Yue Zhang, Juhui Zhao, Chengzhao Deng, Gang Zhao, Yan Cheng, Lingqin Song, Yan Yang, Ruochun Guo, Huan Zhang, Hongli Zhao, Shiyang Ma, Lu Li, Haitao Shi

“…Results Our results revealed a notable shift in the gut virome structure of patients compared to healthy controls, characterized by a significant increase in viral families such as Microviridae, Podoviridae_crAss-like, and Quimbyviridae. …”
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Discriminant analysis of occupational performance characteristics in patients with major depressive disorders and healthy individuals by Tomonari Hayasaka, Izumi Nagashima, Miku Hoshino, Koji Teruya, Yasuyuki Matumoto, Masami Murao, Taku Maruki, Masako Watanabe, Takeshi Katagiri, Yayoi Imamura, Mariko Kurihara, Yuki Oe, Yoshikazu Takaesu, Takashi Tsuboi, Koichiro Watanabe, Hitoshi Sakurai

“…Abstract Aim Assessing symptoms and daily functioning in patients with major depressive disorder (MDD) can be challenging, as their limited self‐monitoring abilities may result in behavior observed during structured interviews not accurately reflecting their daily lives. …”
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Insights from a codesigned dynamic modelling study of child and adolescent obesity in Australia by Alison Hayes, Rebecca Wyse, Anna Lene Seidler, Kylie E Hunter, Rebecca K Golley, Louise A Baur, Anthony D Okely, Kenny Lawson, Jo-An Occhipinti, Louise Freebairn, Simon Keith Chiu, Joseph Carrello, L Kurt Kreuger

“…This research presents insights from a system dynamics model of childhood and adolescent obesity aimed at supporting evidence-based decision-making.Methods A system dynamics model was developed using the best available evidence and data, with input from research and industry experts to map the hypothetical causal structure of the factors contributing to childhood and adolescent obesity in Australia. …”
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Cognition and experience of surgical incisions in patients undergoing laparoscopic surgery with enhanced recovery after surgery protocol: A qualitative study by Hongxia Xu, Yihong Xu, Gongjie Shi, Jiaqi Lu, Liping Zhu, Guibing He, Xiao Liang

“…The data were analyzed via the framework method to identify themes related to incision experiences. …”
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Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells by Verena Schlösser, Helen Louise Lightfoot, Christine Leemann, Seyedeh Elnaz Banijamali, Aathma Merin Bejoy, Shashank Tiwari, Jeffrey L. Schloßhauer, Valentina Vongrad, Andreas Brunschweiger, Jonathan Hall, Karin J. Metzner, Jochen Imig

“…Results: We established that Enoxacin, but not the structurally similar compound nalidixic acid, exhibits strong anti-HIV-1 effects in the T-cell line CEM-SS, but not MT-4. …”
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Anatomical and histological characterization of the filum terminale in dogs by Christoforos Posporis, Javier Espinosa, Martí Pumarola, Ester Blasco Ortega, Jaume Alomar, Koen Santifort, Koen Santifort, Steven De Decker, Karol Lam, Juan José Mínguez, Patricia Álvarez, Vicente Aige-Gil

“…This study presents the first comprehensive anatomical and histological characterization of the normal canine FT, establishing baseline reference data to facilitate the identification of pathomorphological alterations associated with disorders involving this structure, such as tethered cord syndrome.…”
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Virtual Health Research Capacity Strengthening in Low- and Middle-Income Countries: A Systematic Integrative Review by Chelsea M. McGuire, Nikolina Boskovic, Bolatito Betty Fatusin, Pius Ameh, Taylor Reed, Priyanka Jethwani, David Flynn, Jo Cooke, Robert Saper

“…Using NVivo, we coded until theoretical saturation and analyzed data using the constant comparison method. Findings: From 1397 articles, 58 met inclusion criteria. …”
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