Experiences and perceptions of Chinese patients enrolled in a clinical trial assessing tuina and manual therapies for knee osteoarthritis: a nested qualitative study by Luping Liu, Lingyun Zhang, Sina Li, Meiling Cai, Siyu Han, Zhiwen Weng, Qianji Chen, Yixuan Gao, Xiaoming Yang, Yang Zhang, Duoduo Li, Changxin Liu, Ya’nan Sun, Xiyou Wang, Changhe Yu

“…The interviews were conducted by two researchers who have extensive experience interviewing KOA patients, and data were gathered through face-to-face, semi-structured interviews to ensure a high level of information power. …”
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Artificial neural network-based forecasting of air temperature reduction in a tube bank under electric field by Ekuong Tang, Attakorn Asanakham, Thoranis Deethayat, Tanongkiat Kiatsiriroat

“…The study evaluated the optimal ANN model structure, including the appropriate number of neurons in the hidden layer, the number of epochs, and the suitable activation function for predicting heat transfer performance under an electric field. …”
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Effect of environmentally relevant concentrations of estrogens on the aggressive response of male zebrafish by Ying–Ying Zhang, Ying–Ying Zhang, Hong Tao, Hong Tao, Yan–Jun Shen, Yan–Jun Shen, Qi–Liang Chen, Qi–Liang Chen, Zhi–Hao Liu, Zhi–Hao Liu

“…This, in turn, could undermine the competitive and then survival abilities of zebrafish, and potentially affect their population number and structure.…”
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Effects of timely case conferencing between general practitioners and specialist palliative care services on symptom burden in patients with advanced chronic disease: results of th... by Tina Mallon, Josefine Schulze, Nadine Pohontsch, Thomas Asendorf, Jan Weber, Silke Böttcher, Uta Sekanina, Franziska Schade, Nils Schneider, Judith Dams, Michael Freitag, Christiane Müller, Friedemann Nauck, Tim Friede, Martin Scherer, Gabriella Marx

“…Methods The cluster-randomised controlled trial compared a structured palliative care nurse visit followed by an interprofessional case conference to usual care. …”
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Betulinic acid protects against ovarian impairment by decreasing F-2 toxin-induced oxidative stress and inflammation associated with the downregulation of p38 expression in mice by Li Kong, Xinyu Gao, Lijuan Zhu, Xing Lin, You Huang, Chunlin Huang, Wenjiang Yang, Yazhi Chen, Haoqiang Zhao, Jing Wu, Zhihang Yuan, Jin’e Yi

“…Betulinic acid (BA) is a natural pentacyclic lupane-structure triterpenoid that has diverse pharmacological activities. …”
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The death of a neurotrauma trial lessons learned from the prematurely halted randomized evaluation of surgery in elderly with traumatic acute subdural hematoma (RESET-ASDH) trial by R.D. Singh, J.T.J.M. van Dijck, T.A. van Essen, H.P. Nix, R.J.G. Vreeburg, H.F. den Boogert, G.C.W. de Ruiter, B. Depreitere, W.C. Peul

“…Furthermore, non-structured interviews with involved clinical research personnel were conducted. …”
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Is malathion oncogenic for mosquitoes? A transcriptomic and histological study of adults derived from malathion exposed larvae by Audrey Arnal, Erika Burioli, Lisa Jacquin, Sophie Labrut, Stéphane Duchon, Marie Rossignol, Delphine Nicolas, Beata Ujvari, Antoine Dujon, Jordan Meliani, Jérôme Abadie, Frédéric Thomas, Vincent Corbel

“…Here, we quantitatively investigated whether larval exposure to environmentally realistic concentrations of malathion could affect mosquito tissue structure and gene expression profiles of adult Aedes aegypti (yellow fever mosquitoes), using both RNA-seq and histological approaches. …”
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Retention of medical officers in the district health services of the Western Cape, South Africa: An exploratory descriptive qualitative study by Robert J. Mash, Werner Viljoen, Steve Swartz, Mumtaz Abbas, Leigh Wagner, Herma Steyn, Gavin Hendricks, Dusica Stapar, Andrew Williams, Adeloye Adeniji, Johan Schoevers, Paul Kapp

“…Medical officers were purposefully selected in terms of districts, facility types, gender, seniority and perceived likelihood of leaving in the next four years. Semi-structured interviews were performed by family physicians, and the qualitative data were analysed using the framework method. …”
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Impact of young people’s admissions to adult mental health wards in England: national qualitative study by Anne-Marie Burn, Josephine Holland, James Roe, Elinor Hopkin, Lorna Wild, Michelle Fisher, Tamsin Ford, Saeed Nazir, Bernadka Dubicka, Anthony James, Helena Tuomainen, Nicole Fung, Adam Wagner, Richard Morriss, Kapil Sayal

“…Aims To explore the impact of young people’s admissions to adult wards, from the perspectives of young people, parents/carers and mental health professionals working in adult services. Method Semi-structured interviews were conducted with 29 participants to explore experiences of receiving and delivering care in adult mental health wards. …”
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The interaction of UBR4, LRP1, and OPHN1 in refractory epilepsy: Drosophila model to investigate the oligogenic effect on epilepsy by Rui-Na Huang, Si-Yuan Luo, Tao Huang, Xiong-Sheng Li, Fan-Chao Zhou, Wei-Hao Yin, Ze-Ru Chen, Shi-Zhan Yuan, Ling-Ying Li, Bin Tang, Jing-Da Qiao

“…This study established a novel framework to clarify the multiple genetic structure of epileptogenicity in refractory epilepsy with oligogenic background, which could be critical to translational medicine and precision therapy development.…”
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Protocol for PD SENSORS: Parkinson’s Disease Symptom Evaluation in a Naturalistic Setting producing Outcome measuRes using SPHERE technology. An observational feasibility study of... by Catherine Morgan, Walter Maetzler, Oliver Watson, Lynn Rochester, Ian Craddock, Helen Matthews, Emma L Tonkin, Kirsi M Kinnunen, Roisin McNaney, Sam Whitehouse, Majid Mirmehdi, Farnoosh Heidarivincheh, Ryan McConville, Julia Carey, Michal Rolinski, Rachel Eardley, Alan L Whone

“…Acceptability of the technology will be evaluated qualitatively using semi-structured interviews.Ethics and dissemination Ethical approval has been given to commence this study; the results will be disseminated as widely as appropriate.…”
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Jet-fuel range hydrocarbon production from Reutealis trisperma oil over Al-MCM-41 derived from Indonesian Kaolin with different Si/Al ratio by Reva Edra Nugraha, Didik Prasetyoko, Nabila Argya Nareswari, Abdul Aziz, Holilah Holilah, Hasliza Bahruji, Muhammad Rahimi Yusop, Nurul Asikin-Mijan, Suprapto Suprapto, Yun Hin Taufiq-Yap, Aishah Abdul Jalil, Santi Wulan Purnami, Hartati Hartati

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Developing a national clinical competency committee for family medicine training, South Africa by Louis S. Jenkins, Mergan Naidoo, Kefilwe Hlabyago, Dirk T. Hagemeister, Neetha Erumeda, Busisiwe Cawe, Tasleem Ras, Mulimisi Ramavhuya, Owen Eales

“…These EPAs provide a structured approach to assessing and developing the competencies required for independent practice in family medicine. …”
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Prioritising Key Concepts for informed health choices in cancer: An evidence-based online educational programme by Mengqi Li, Declan Devane, Claire Beecher, Maura Dowling, Austin G. Duffy, Caitriona Duggan, David Robert Grimes, Avril Kennan, Claire Kilty, Allen Nsangi, Andrew D. Oxman, Derek C. Stewart, Elaine Toomey, Marie Tierney

“…The process involved disseminating pre-reading materials, training sessions, and a structured judgement form to evaluate concepts for inclusion. …”
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Dynamics of Reconnection Nanojets in Eruptive and Confined Solar Flares by Annu Bura, Arpit Kumar Shrivastav, Ritesh Patel, Tanmoy Samanta, Sushree S Nayak, Ananya Ghosh, Shanwlee Sow Mondal, Vaibhav Pant, Daniel B. Seaton

“…We infer that this sheared arcade configuration in the eruptive event creates favorable conditions for higher speeds and kinetic energies, unlike the less braided structure in the confined event. Our findings highlight the crucial role of the surrounding magnetic environment in regulating the energetics of nanoflare ejections in the solar atmosphere.…”
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Anaemia during pregnancy: a cross-sectional study of antenatal attendants at the Madina Pentecost Hospital, La Nkwantanang Municipality, Ghana by Richard Vikpebah Duneeh, Wina Ivy Ofori Boadu, Lois Tekutey Narh, Joseph Frimpong, Abdul-Wahab Mawuko, John Gameli Deku, Kofi Mensah, Charles Nkansah, Samuel Kwasi Appiah, Felix Osei Boakye, Enoch Odame Anto, Lilian Antwi Boateng, Benedict Sackey, Otchere Addai-Mensah

“…This cross-sectional study conveniently recruited 300 Ghanaian pregnant women attending the Madina Pentecost Hospital for antenatal care. A structured questionnaire was administered to obtain data on sociodemographics (age, marital status, level of education, occupation and religion) and knowledge level of anaemia. …”
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PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescue by Melanie J. Ludlow, Oleksandr V. Povstyan, Deborah M. Linley, Silvia Martin-Almedina, Charlotte Revill, Kevin Cuthbertson, Katie A. Smith, Emily Fay, Elisavet Fotiou, Andrew Bush, Claire Hogg, Tobias Linden, Natalie B. Tan, Susan M. White, Juan C. Del Rey Jimenez, Ege Sackey, Esther Dempsey, Sahar Mansour, Gregory Parsonage, Antreas C. Kalli, Richard Foster, Pia Ostergaard, David J. Beech

“…Two of the variants encode amino acid changes in the channel’s cap structure (Ile2270Thr and Arg2335Gln), one in the ninth transmembrane helical unit (THU) below the cap (Gly1978Asp) and one in the fifth THU distant from the cap (Glu829Val). …”
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Association of cancer and outcomes of patients hospitalized for COVID-19 between 2020 and 2023 [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Robert F Terry, Rugiatu Z Kamara, Robert J Samuels, Donald S Grant, Sulaiman Lakoh, Mustapha Kabba, Innocent Nuwagira, Yusuf Sheku Tejan, Sia Morenike Tengbe, Ibrahim Franklyn Kamara, Shermarke Hassan, Abdulai Tejan Jalloh, Divya Nair, Laura Merson

“…Methods We conducted an analysis on data collected in a large prospective cohort study set-up by the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC). …”
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Functional work disability from the perspectives of persons with systemic lupus erythematosus: a qualitative thematic analysis by Behdin Nowrouzi-Kia, Aaron S. Howe, Anson Li, Jeremy Tan, Natalia Saade-Cleves, Kevon Jules, Malak Sadek, Ali Bani-Fatemi, Antonio Avina-Zubieta, Mary T. Fox, William Shaw, Derek Haaland, Janet Pope, Paul R. Fortin, Kathleen S. Bingham, Christine Peschken, Jennifer Reynolds, Catherine Ivory, Dafna D. Gladman, Murray B. Urowitz, Jorge Sanchez-Guerrero, Lily S. H. Lim, Stephanie Keeling, Patti Katz, Mahta Kavkan, Dennisse Bonilla, Wils Nielsen, Zahi Touma

“…Methods With the objective of creating an SLE-related functional profile rooted in work disability (WD) prevention, 46 SLE patients were purposively recruited from Canadian medical centres. Through semi-structured interviews guided by a WD prevention framework, factors associated with WD and lived experiences of SLE-related WD were qualitatively explored. …”
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Tour of Asteroids for Characterization Observations (TACO): A Planetary Defense Asteroid Tour Concept by Angela M. Stickle, Andrew S. Rivkin, Justin Atchison, Jodi Berdis, Rylie Bull, Andy Cheng, R. Terik Daly, Carolyn M. Ernst, Patrick King, Meagan Leary, Emma S. G. Rainey, Ronald J. Vervack Jr., Nancy Chabot

“…The TACO tour concept is specifically designed to measure the most important asteroid properties for planetary defense, including mass, size/shape, surface and near-surface structure, presence of satellites, and composition. …”
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