SVLearn: a dual-reference machine learning approach enables accurate cross-species genotyping of structural variants by Qimeng Yang, Jianfeng Sun, Xinyu Wang, Jiong Wang, Quanzhong Liu, Jinlong Ru, Xin Zhang, Sizhe Wang, Ran Hao, Peipei Bian, Xuelei Dai, Mian Gong, Zhuangbiao Zhang, Ao Wang, Fengting Bai, Ran Li, Yudong Cai, Yu Jiang

“…Abstract Structural variations (SVs) are diverse forms of genetic alterations and drive a wide range of human diseases. …”
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A specialized reference panel with structural variants integration for improving genotype imputation in Alzheimer disease and related dementias by Po-Liang Cheng, Hui Wang, Beth A. Dombroski, John J. Farrell, Iris Horng, Tingting Chung, Giuseppe Tosto, Brian W. Kunkle, William S. Bush, Badri Vardarajan, Gerard D. Schellenberg, Wan-Ping Lee

“…Recognizing the importance of associations between structural variants (SVs) and AD and their underrepresentation in existing public reference panels, our panel uniquely integrates single-nucleotide variants (SNVs), short insertions or deletions (indels), and SVs. …”
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Quantitative and structural features of the SMN1 and SMN2 genes in patients with spinal muscular atrophy 5q by A. I. Vlasenko, V. D. Nazarov, S. V. Lapin, A. V. Mazing, E. A. Surkova, T. V. Blinova, T. M. Alekseeva

“…Description of quantitative and structural features of the SMN1 and SMN2 genes in patients with SMA 5q.Materials and methods. …”
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The mediating role of daily living ability and sleep in depression and cognitive function based on a structural equation model by Liu Huijun, Zhang Xiange, Yang Ming, Sun Jiayi, Peng Juanjuan, Xu Wangquan, Song Yueli, Fang Guixia

“…Pearson correlation analysis was employed to test the relationship between depression symptoms, cognition, poor sleep quality and daily living ability of the elderly. The structural equation model was used to explore the link between depression and cognition in the older adults, and to test mediating effects of daily activity and sleep disturbance on depression and cognition. …”
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Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Dementia diagnosis was ascertained from inpatient and death register data.Results Over a median 12.0-year follow-up, 3998 all-cause dementia cases were identified. …”
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Exploring effector-host interactions in Pyricularia oryzae infections: A molecular and structural approach to rice blast resistance by Zakir Amin, F.A. Mohiddin, Ali Anwar, Asif B. Shikari, Sajad Un Nabi, Tauseef A. Bhat, Vishal Gupta, Fehim Jeelani Wani, Shugufta Parveen, Mohd Salim Mir, Subaya Manzoor, Suhail Ashraf, Mohammad Raish

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Radiomics prediction of MGMT promoter methylation in adult diffuse gliomas: a combination of structural MRI, DCE, and DTI by Yuying Liu, Yuying Liu, Zhengyang Zhu, Jianan Zhou, Han Wang, Huiquan Yang, Jinfeng Yin, Yitong Wang, Xin Li, Futao Chen, Qian Li, Zhuoru Jiang, Xi Wu, Danni Ge, Yi Zhang, Xin Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang

“…PurposeTo assess the predictive value of radiomics features extracted from structural MRI, dynamic contrast enhanced (DCE), and diffusion tensor imaging (DTI) in detecting O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in patients with diffuse gliomas.MethodsRetrospective MRI data of 110 patients were enrolled in this study. …”
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Mechanical behavior and mechanisms of superplastic deformation of aluminum alloys exhibiting the effect of structural superplasticity in solid and in solid−liquid states by В.П. Пойда, А.В. Пойда, Д.Є. Мила

“…The article presents the results of research aimed at summarizing experimental data on the mechanical behavior, structural state and mechanisms of superplastic deformation of aluminum alloys Al-4 wt.% Ge, Al-4.1 wt.% Cu-0,5 wt.% Zr, 1420T, 1933. …”
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Risk factors for anastomotic structural malhealing after laparoscopic intersphincteric resection for rectal cancer and its impact on prognosis by Hu Gang, Liu Junguang, Li Bo, Wang Yuhan, Qiu Wenlong, Mei Shiwen, Quan Jichuan, Zhuang Meng, Tang Jianqiang

“…[Objectives] To investigate the risk factors for anastomotic structural malhealing after laparoscopic intersphincteric resection (lap-ISR) for rectal cancer and its impact on patient prognosis. …”
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The Current Status of Medical Parasitology in Iran: Developing a Roadmap, Structural Mapping, and Proposed Scenarios for the Future of this Field by Seyed Mahmoud Sadjjadi, Mehdi Mohebali, Iraj Sharifi, Abdolhossein Dalimi Asl, Ali Haghighi, Abdollah Rafiei, Mostafa Rezaeian, Gholamhossein Edrissian, Hossein Keshavarz Valian, Mohammad Bagher Rokni, Mohammad Fallah, Hossein Yousefi Darani, Elham Razmjoo, Mehrzad Saraei, Ali Haniloo, Hossein Hooshyar, Ali Ehsan Heidari, Shirzad Gholami, Mahmoud Mahami Oskouei, Farnaz Kheirandish, Tahereh Mohammadzadeh, Yosef Sharifi

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Mechanism of fumonisin B1 on growth performance and intestinal structural integrity of juvenile grass carp (Ctenopharyngodon idella) by Daiyu Chen, Weidan Jiang, Pei Wu, Yang Liu, Hongmei Ren, Xiaowan Jin, Xiaoqiu Zhou, Lin Feng

“…Furthermore, increased levels of intestinal sphinganine (Sa), sphingosine (So), and FB1 residues were observed, along with disruptions in intestinal tissue structure and elevated serum D-lactic acid levels (P < 0.05). …”
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The Mappability of Clinical Real-World Data of Patients with Melanoma to Oncological Fast Healthcare Interoperability Resources (FHIR) Profiles: A Single-Center Interoperability St... by Jessica Swoboda, Moritz Albert, Catharina Lena Beckmann, Georg Christian Lodde, Elisabeth Livingstone, Felix Nensa, Dirk Schadendorf, Britta Böckmann

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Advancing thyroid diagnosis: integrating AI-driven CAD framework with numerical data and ultrasound images by Saleh Ateeq Almutairi

“…The proposed CAD framework employs the sparse search algorithm (SSA) for optimized feature selection from numerical data and the tree-structured Parzen estimator for tuning the hyperparameters. …”
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Probing the He ii re-Ionization ERa via Absorbing C iv Historical Yield (HIERACHY). II. Project Design, Current Status, and Examples of Initial Data Products by Jiang-Tao Li, Xiaodi Yu, Huiyang Mao, Hanxiao Chen, Tiancheng Yang, Zhijie Qu, Fuyan Bian, Joel N. Bregman, Zheng Cai, Xiaohui Fan, Taotao Fang, Li Ji, Zhiyuan Ji, Sean D. Johnson, Guoliang Li, Weizhe Liu, Ying-Yi Song, Feige Wang, Tao Wang, Xin Wang, Christina Williams, Mingxuan Xu, Jinyi Yang, Yang Yang, Xianzhong Zheng

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Selected problems of design and construction of the 19th century railway bridges by example of Ivangorod–Dąbrowa Railway by Wiktor Wściślik, Maciej K. Cichoń

“…The route as a whole is characterized, along with a discussion of statistical data regarding the bridges located along the line in question. …”
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Ground Motion Recording-Based Validation of Capacity Curves for High-Rise Reinforced Concrete Structures in Romania Constructed Before 1977 by Florin Pavel

“…Finally, updated capacity curves for high-rise residential structures constructed before 1977 are proposed by combining the analytical results with the earthquake data.…”
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2-Amino-4-ferrocenyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile monohydrate by Carren Nyapola, David O. Juma, Sizwe J. Zamisa, Eric M. Njogu, Bernard Omondi

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rac-4,5-trans-Dibromo-9,9-dichloro-cis-bicyclo[6.1.0]nonane by Heiner Detert, Dieter Schollmeyer

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(3Z)-4-Methyl-9-(4-methylbenzenesulfonyl)-N-phenyl-3H,9H-thiopyrano[3,4-b]indol-3-imine by Benjamin Dassonneville, Heiner Detert, Dieter Schollmeyer

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rac-2-{3-[1-(Acetyloxy)ethyl]-2,2-dimethylcyclobutyl}acetic acid by Dieter Schollmeyer, Paul Jirsch, Heiner Detert

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