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52701
Cell-derived exosome therapy for diabetic peripheral neuropathy: a preclinical animal studies systematic review and meta-analysis
Published 2025-06-01“…The outcome indicators consisted of at least one of the three key DPN endpoints (electrophysiology, behavioural assessment, and nerve structure) based on the Neurodiab guidelines. R 4.4.2 software was used to conduct all statistical analyses. …”
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52702
Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway
Published 2025-01-01“…Background and aimsPatients with Crohn’s disease (CD) exhibit excessive apoptosis of intestinal epithelial cells (IECs), which contributes to damage to the intestinal barrier structure and function, thereby playing a role in the progression of colitis. …”
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52703
Population-based cross-sectional seroprevalence study of SARS-CoV-2 infection in urban residential areas in Ghana
Published 2025-02-01“…Bayesian models with poststratification weighting of the demographic structure of the sample population were used for seroprevalence estimates, accounting for the uncertainty of diagnostic assay in a hierarchical model. …”
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52704
Evaluation of control strategies for airport refueling system
Published 2024-09-01“…Subsequently, within the setting of an airport in China, encompassing its actual pipeline network structure and refueling data, simulations were conducted, incorporating different control modes (single-pump frequency conversion and multi-pump frequency conversion) and diverse measurement parameters (pressurefrequency and pressure-flow). …”
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52705
Manipulation in root-associated microbiome via carbon nanosol for plant growth improvements
Published 2024-11-01“…Fungal and bacterial communities had different response patterns for CNS treatment, with phased and dose-dependent effects, with the most significant changes in microbial community structure observed at 1200 mg/L after 10 days of treatment. …”
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52706
The Improvement Effects of Intercropping Systems on Saline-Alkali Soils and Their Impact on Microbial Communities
Published 2025-06-01“…Simultaneously, intercropping affects the soil microbial community structure of subsequent crops; however, the responses of bacteria and fungi to intercropping are significantly different. …”
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52707
Mitochondrial genome assembly and comparative analysis of decaploid Camellia hainanica
Published 2025-06-01“…Therefore, assembling and annotating the mitochondrial genome function of decaploid C. hainanica is of great significance.MethodsThis study successfully assembled the mitochondrial genome of decaploid C. hainanica and comprehensively annotated its functional genes using the Nanopore sequencing platform.ResultsResults showed that the mitochondrial genome is 902,617 bp in length, with a typical circular structure and a guanine–cytosine content of 45.79%. …”
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52708
β-diversity of the herbaceous layer plant communities in natural forests and its influencing factors in Henan Province
Published 2024-10-01“…Conducting research on β-diversity(beta diversity)and its components, which reflect spatial or temporal variations in species composition among communities, helps to improve the understanding and knowledge of community structure and its maintenance mechanisms. The herbaceous layer of forest is an important part of forest community and forest ecosystem. …”
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52709
Exploration of the relationship between partial pressure of brain tissue oxygen and intracranial pressure
Published 2024-01-01“…Material and methods: Patients with PbtO2 monitoring were identified from the BrainIT database, a multi-centre dataset, containing minute by minute PbtO2 and ICP readings. Missing data was imputed and a multi-level log-normal regression model with a compound symmetry correlation structure was built. …”
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52710
COZMIC. I. Cosmological Zoom-in Simulations with Initial Conditions Beyond Cold Dark Matter
Published 2025-01-01“…Thus, future development of IDM SHMF models can improve IDM cross section bounds by up to a factor of ∼20 with current data. COZMIC presents an important step toward accurate small-scale structure modeling in beyond-CDM cosmologies, critical to upcoming observational searches for dark matter physics.…”
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52711
Helping people with psychosis with a low-cost intervention DIALOG+: protocol for the economic evaluation in a randomised control trial in India and Pakistan
Published 2025-01-01“…Incremental cost, incremental effectiveness and incremental cost-effectiveness ratios will be calculated using linear regression models with a hierarchical data structure. A probabilistic sensitivity analysis will be carried out to test for the uncertainty surrounding the estimates of cost-effectiveness.Discussion This study will provide evidence of a patient-centred approach to improve the quality of community-based care for people with psychosis in India and Pakistan. …”
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52712
Effects and mechanisms of supramaximal high-intensity interval training on extrapulmonary manifestations in people with and without chronic obstructive pulmonary disease (COPD-HIIT...
Published 2024-10-01“…Key secondary outcomes include change from baseline exercise tolerance, brain structure, and function measured by MRI, neuroinflammation measured by PET/CT, systemic inflammation, and intramuscular adaptations. …”
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52713
Development and Characterization of Pyrolyzed Sodium Alginate–Montmorillonite Composite for Efficient Adsorption of Emerging Pharmaceuticals: Experimental and Theoretical Insights...
Published 2025-05-01“…Using Density Functional Theory (DFT) along with the 6-31G (d) basis set, the geometric structure of the molecule was determined, and the properties were estimated by analyzing its boundary molecular orbitals. …”
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52714
Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents
Published 2024-07-01“…In the classic supply chain, the flow of materials and output at the end of the chain includes the manufactured product, while in the construction supply chain, the final output includes a building or a structure. Individuals, industries and even countries incur a lot of construction costs to meet their needs in the field of construction. …”
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52715
Validation of a questionnaire to assess complexity of palliative care needs in primary care in Malaga, Spain: a study protocol
Published 2025-07-01“…A specific diagnostic tool to assess complexity in PC (IDC-Pal: Instrumento Diagnóstico de la Complejidad en Cuidados Paliativos, in Spanish) was created in community and hospital settings with 36 items to diagnose PC complexity, but its application in primary care is difficult.Aims (1) To generate an adapted version to primary care of the IDC-Pal tool to identify and stratify PC complexity in the adult population. (2) To determine face, content, criterion and construct validity and reliability of the new instrument.Methods and analysis There are three phases of clinimetric cross-sectional observational validation study: Phase 0: Review of the original tool structure suitability for its use in primary care setting by a committee (researchers and the original developer team). …”
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52716
Geospatial Innovation Breakthroughs: A Study on the Impact of Talent Birthplace Diversity and Multidimensional Proximity
Published 2025-02-01“…However, the global distribution of technological innovation remains uneven, with a sustained "core-periphery" structure. From the perspective of evolutionary economic geography, technological development paths are closely linked to the local knowledge base, making it generally difficult to overcome spatial constraints. …”
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52717
Taxonomic composition, distribution and resources of macrobenthos in Peter the Great Bay in 2011
Published 2017-09-01“…Anyway, the dominant taxonomic groups of Peter the Great Bay macrobenthos were constantly bivalves and polychaetes (and barnacles in the Amur Bay) and all changes in taxonomic structure or even replacing each other concerned the subdominant and minor taxa. …”
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52718
Synthesis and study of the anticancer activity of some new 7H-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazines
Published 2021-12-01“…The reaction proceeds by heating the above reagents in alcohol with the closure of the thiadiazine ring and the formation of 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine systems. The structure of all synthesized compounds was confirmed by 1H NMR spectroscopy and elemental analysis data. …”
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52719
Device optimization of CsPbI2Br-based inorganic perovskite solar cells using different charge transport layers via SCAPS-1D
Published 2025-07-01“…We hope our findings will contribute to understanding the Perovskite solar cells (PSCs) structure with different hole transport layers, and ultimately lead to the development of more efficient, stable, and cost-effective perovskite solar cells for commercial applications.…”
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52720
Asteroseismology of One of the Most Rapidly Rotating DBV Stars: EPIC 248705247
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