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  1. 52021
  2. 52022

    Cost-effectiveness of FIT and a FIT-based model to optimise symptomatic diagnosis of colorectal cancer: health economic modelling for the COLOFIT project by Linda Sharp, Sarah Bailey, Colin Rees, Willie Hamilton, Dawn Craig, Joe West, David Humes, Gary Abel, James Turvill, Brian Nicholson, Chloe Thomas, Jim Chilcott, Colin Crooks, Olena Mandrik, John Whelpton

    Published 2025-06-01
    “…Cost-effectiveness improves as risk thresholds rise. High structural uncertainty around cancer progression during diagnostic delay and diagnosis of other serious bowel diseases considerably affects cost-effectiveness.Conclusions COLOFIT is likely to be more cost-effective than FIT alone and could help alleviate pressure on diagnostic services. …”
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    Article
  3. 52023

    Deep sphingolipidomic and metabolomic analyses of ceramide synthase 2 null mice reveal complex pathway-specific effects by Jeongah Oh, Sneha Muralidharan, Qing Zhao, Johannes Scholz, Iris D. Zelnik, Shani Blumenreich, Tammar Joseph, Tamir Dingjan, Pradeep Narayanaswamy, Hyungwon Choi, Heiko Hayen, Federico Torta, Anthony H. Futerman

    Published 2025-07-01
    “…The sphingolipidome contains thousands of structurally distinct sphingolipid (SL) species. This enormous diversity is generated by the combination of different long-chain bases (LCBs), N-acyl chains and head groups. …”
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    Article
  4. 52024

    Insights from one American Indian tribe about heart health by Sarah de Loizaga, McCall Miller, Barbie Giambra, LeCario Benashley, Billie Bones, Samantha Buonfiglio, Gwendena Lee Gatewood, Amanda Paxson, Teresa Pestian, Rachel Sarnacki, Rhiannon Walker, Dawnafe Whitesinger, Andrea Beaton, Lisa M. Vaughn

    Published 2025-08-01
    “…Methods: We used qualitative semi-structured interviews to examine Tribal experiences and perspectives surrounding heart health and health in general on Tribal lands. …”
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    Article
  5. 52025

    Sociodemographic factors associated with trajectories of depression among urban refugee youth in Kampala, Uganda: A longitudinal cohort study by Zerihun Admassu, Sikky Shiqi Chen, Carmen H. Logie, Moses Okumu, Frannie MacKenzie, Robert Hakiza, Daniel Kibuuka Musoke, Brenda Katisi, Aidah Nakitende, Peter Kyambadde, Lawrence Mbuagbaw

    Published 2024-01-01
    “…Sociodemographic (older age, gender [cisgender women vs. cisgender men], longer time in Uganda), and socioecological (structural: unemployment, food insecurity; interpersonal: parenthood, recent intimate partner violence) factors were significantly associated with the sustained high trajectory of depression. …”
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    Article
  6. 52026

    Empowering knowledge graphs with hybrid retrieval-augmented generation for the intelligent mix scheme of mass concrete by Yuqing Shang, Zhijiang Ke, Peng Lin, Qianhui Ren, Wenshan Zhang, Xiongwu Wang, Xiaotao Li, Fuyuan Gong, Shiqi Wang, Baofa Wang, Zhengkui Xu, Minglun Sun, Shunli Tan

    Published 2025-12-01
    “…Firstly, a total of 1723 mix proportioning records collected from 15 hydropower stations were structurally extracted using a customized data transformation tool. …”
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    Article
  7. 52027

    Uncovering the breeding contribution of transposable elements from landraces to improved varieties through pan-genome-wide analysis in rice by Xiaoxia Li, Xiaoxia Li, Xiaofan Dai, Xiaofan Dai, Huiying He, Wu Chen, Qian Qian, Qian Qian, Lianguang Shang, Lianguang Shang, Longbiao Guo, Wenchuang He

    Published 2025-04-01
    “…Advances in pan-genomes and enhanced capacity for analyzing structural variations have increasingly highlighted their role in rice genetic improvement. …”
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    Article
  8. 52028

    Medium-Chain Acyl-CoA Deficiency: Outlines from Newborn Screening, In Silico Predictions, and Molecular Studies by Serena Catarzi, Anna Caciotti, Janita Thusberg, Rodolfo Tonin, Sabrina Malvagia, Giancarlo la Marca, Elisabetta Pasquini, Catia Cavicchi, Lorenzo Ferri, Maria A. Donati, Federico Baronio, Renzo Guerrini, Sean D. Mooney, Amelia Morrone

    Published 2013-01-01
    “…Bioinformatics predictions based on both phylogenetic conservation and functional/structural software were used to characterize the new identified variants. …”
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    Article
  9. 52029

    A mixed-methods assessment of the Australasian Society of Genetic Counselors (ASGC) Mentor Program by Holly Canton, Rebecca Macintosh, Joanna Sweeting, Helen Mountain, Jodie Ingles, Amy Nisselle, Erin Turbitt, Alison McEwen, Laura Yeates

    Published 2024-01-01
    “…Methods: We used an explanatory mixed-method design with cross-sectional surveys deployed at baseline and follow-up and opt-in semi-structured interviews. Interview transcripts were analyzed using codebook thematic analysis, and data were integrated in a narrative approach. …”
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    Article
  10. 52030

    Preoperative subjective impairments in language and memory in brain tumor patients by Lena Rybka, Lena Rybka, Lena Rybka, Roel Jonkers, Roel Jonkers, Milena Burzlaff, Milena Burzlaff, Tizian Rosenstock, Tizian Rosenstock, Peter Vajkoczy, Thomas Picht, Thomas Picht, Katharina Faust, Adrià Rofes, Adrià Rofes

    Published 2024-10-01
    “…Group and subgroup analyses were conducted to provide general and tumor grade specific data.Results48.4% of patients mentioned co-occurrence of language and memory impairments in reading, writing, and conversation. …”
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  11. 52031
  12. 52032
  13. 52033
  14. 52034

    Temperature and excipient mediated modulation of monoclonal antibody interactions revealed by kD, rheology, and Raman spectroscopy by Olivia Noelle Eskens, Sabitoj Singh Virk, Akashdeep Singh Virk, Deepika Venkataramani, Maureen Crames, Maria Calderon Vaca, Matthew Matusewicz, Connor Smith, Joshin George, Collin Taylor, Michael S. Marlow, Samiul Amin

    Published 2025-12-01
    “…Raman spectral analysis of Amide I/III regions confirmed structural invariance under thermal and shear stress, attributing viscosity modulation to colloidal rather than conformational perturbations. …”
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  15. 52035
  16. 52036
  17. 52037

    EXPERIMENTAL EVALUATION OF LONG-TERM ADVERSE SIDE EFFECTS OF CYTOSTATIC DRUGS ON FEMALE REPRODUCTIVE FUNCTION AND PHARMACOLOGICAL WAYS TO REDUCE THEM by T. G. Borovskaya, V. E. Goldberg, M. E. Poluektova, A. V. Vychuzhanina, Yu. A. Shchemerovа, V. A. Grigoreva, A. A. Ligacheva, E. A. Bokhan

    Published 2021-03-01
    “…Statistical processing of obtained experimental data was performed using Mann-Whitney U-test and Fisher angular transformation.Results. …”
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  18. 52038

    Development of the 10-question household foodwork interactional assessment questionnaire (FIA-Q10) by Leah E. Cahill, Sharon I. Kirkpatrick, Catherine L. Mah, Jennifer LP. Protudjer, Cynthia Kendell, Mary E. Jung, Helen Wong, Ellen T. Crumley, Meghan Day, Karen T. Y. Tang, Yan Huang, Jyoti Sihag, Laura Brady, Karthik K Tennankore, Navdeep Tangri, Rebecca C. Mollard, Dylan MacKay

    Published 2024-11-01
    “…An optional accompanying module was developed to collect self-identified demographic data to provide context for understanding how social-structural positionality factors may interact to influence foodwork. …”
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    Article
  19. 52039

    Preliminary observations of glucose metabolism dysregulation in pediatric Huntington’s disease by Federica Graziola, Federica Rachele Danti, Martina Penzo, Antonio Spagarino, Eleonora Minacapilli, Marco Moscatelli, Federica Zibordi, Caterina Mariotti, Giovanna Zorzi, Giovanna Zorzi

    Published 2025-08-01
    “…Clinical, neuroimaging, and neuropsychological data were collected alongside metabolic assessments, including cerebrospinal fluid (CSF) and plasma glucose and lactate levels, CSF-to-serum glucose ratio, and red blood cell GLUT1 expression using the METAglut1 test. 18F-FDG PET imaging and brain MRI were performed to assess cerebral metabolism and structural changes.ResultsBoth patients exhibited progressive motor and cognitive decline with dystonia-parkinsonian features, learning disabilities, and behavioral disturbances. …”
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  20. 52040