Preliminary observations of glucose metabolism dysregulation in pediatric Huntington’s disease by Federica Graziola, Federica Rachele Danti, Martina Penzo, Antonio Spagarino, Eleonora Minacapilli, Marco Moscatelli, Federica Zibordi, Caterina Mariotti, Giovanna Zorzi, Giovanna Zorzi

“…Clinical, neuroimaging, and neuropsychological data were collected alongside metabolic assessments, including cerebrospinal fluid (CSF) and plasma glucose and lactate levels, CSF-to-serum glucose ratio, and red blood cell GLUT1 expression using the METAglut1 test. 18F-FDG PET imaging and brain MRI were performed to assess cerebral metabolism and structural changes.ResultsBoth patients exhibited progressive motor and cognitive decline with dystonia-parkinsonian features, learning disabilities, and behavioral disturbances. …”
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CD300f epitopes are specific targets for acute myeloid leukemia with monocytic differentiation by Edward Abadir, Robin E. Gasiorowski, Kaitao Lai, Fiona Kupresanin, Adelina Romano, Pablo A. Silveira, Tsun‐Ho Lo, Phillip D. Fromm, Marina L. Kennerson, Harry J. Iland, P. Joy Ho, P. Mark Hogarth, Kenneth Bradstock, Derek N.J. Hart, Georgina J. Clark

“…Furthermore, binding of one mAb, DCR‐2, to CD300f exposes a structural epitope recognized by a second CD300f mAb, UP‐D2. …”
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Genome-wide identification of the AcBAM family in kiwifruit (Actinidia chinensis cv. Hongyang) and the expression profiling analysis of AcBAMs reveal their role in starch metabolis... by Xuchen Gong, Mengfei Lin, Jie Song, Jipeng Mao, Dongliang Yao, Zhu Gao, Xiaoling Wang

“…., Glu186 and Glu380) and exhibited similar structural properties. Phylogenetic and collinearity analyses grouped the genes into three main clusters, with segmental and tandem duplications contributing to their expansion. …”
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The Relationship between Personality Disorders and Parent\'s Social Capital with the Social Health of Children and Adolescents in Yazd by Nastaran Ahmadi, Parvane Rashidpour, Mohammadreza Mohammadi, Mohammadhadi Farahzadi, Javad Ardeshirpay, Hosein Abouzari, Malihe Mobini, Masoud Mirzaei, Amirhoushang Mehrparvar, Fatemeh Rismanian Yazdi

“…Millon's test of fathers demonstrates a significant correlation with the average scores of structural social capital, cognitive social capital, communicative social capital, and total social capital (P-value < 0.001). …”
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Promoting active behaviours in schoolchildren using the socio-ecological model in the physical education class: study protocol of the ACTIBESE project by Fernando Rodríguez-Rodríguez, Carlos Cristi-Montero, Natalia Zurita-Corvalán, Caroline Brand, Jorge Mota, Palma Chillón, Anelise Reis Gaya, Javier Brazo-Sayavera, Nicolás Aguilar-Farias

“…The research will use mixed models, ANCOVA, and logistic regressions for data analysis, network analysis, exploratory factors analysis, and structural equation modelling. …”
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The role of neotectonics and climate variability in the Pleistocene-to-Holocene hydrological evolution of the Fuente de Piedra playa lake (southern Iberian Peninsula) by A. Jiménez-Bonilla, L. Martegani, L. Martegani, M. Rodríguez-Rodríguez, F. Gázquez, F. Gázquez, M. Díaz-Azpíroz, S. Martos, K. Reicherter, I. Expósito

“…We conducted an interdisciplinary study combining structural, geomorphic, sedimentological, mineralogical and hydrological analyses to better understand the evolution of the Fuente de Piedra (FdP) playa lake in southern Spain. …”
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Assessing the foreign economic security of Ukraine by Yuliia Yehorova, Svitlana Chorna, Yuriy Petrushenko, Fedir Zhuravka, Khrystyna Potapenko, Iryna D’yakonova, Oksana Zamora

“…At the same time, the growth of foreign economic security is recorded in the period of stabilization during the implementation of structural reforms: 2005–2008 – the period after the Orange Revolution, 2014–2016 – the period of growth after the Revolution of Dignity, 2021 – post-pandemic recovery. …”
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Bioactive Chalcones from <i>Aizoon africanum</i>: Isolation and Cytotoxicity Against Liver and Neural Cancer Cells by Ali O. E. Eltahir, Naeem Sheik Abdul, Taskeen F. Docrat, Paolo Bristow, Elias Chipofya, Robert C. Luckay, Monde A. Nyila, Jeanine L. Marnewick, Kadidiatou O. Ndjoubi, Ahmed A. Hussein

“…The methanolic extract of <i>A. africanum</i> was re-investigated and subjected to various chromatographic techniques, including preparative HPLC, resulting in the isolation of eight compounds (<b>1</b>–<b>8</b>). Structural elucidation was primarily based on NMR data. …”
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Generating synthetic brain PET images of synaptic density based on MR T1 images using deep learning by Xinyuan Zheng, Patrick Worhunsky, Qiong Liu, Xueqi Guo, Xiongchao Chen, Heng Sun, Jiazhen Zhang, Takuya Toyonaga, Adam P. Mecca, Ryan S. O’Dell, Christopher H. van Dyck, Gustavo A. Angarita, Kelly Cosgrove, Deepak D’Souza, David Matuskey, Irina Esterlis, Richard E. Carson, Rajiv Radhakrishnan, Chi Liu

“…The image translation accuracy was evaluated based on the mean squared error, structural similarity index, percentage bias and Pearson’s correlation coefficient between the ground truth and the predicted images. …”
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A detailed investigation of induced residual stresses in the laser powder bed fusion process using the modified inherent strain approach and experimental measurements by Marjan Molavi-Zarandi, Ali Bonakdar, Hossein Mohammadtaheri, Mehran Bagheri, Ramin Sedaghati

“…By offering a comprehensive depth-resolved analysis, this work provides new insights into subsurface stress evolution, critical for ensuring the structural integrity of LPBF parts. The study provides a critical assessment of the MIS method's capabilities and offers essential guidance for future research opportunities to improve residual stress predictions in LPBF-produced parts.…”
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Deep learning radiomics of left atrial appendage features for predicting atrial fibrillation recurrence by Yanping Yin, Sixiang Jia, Jing Zheng, Wei Wang, Ziwen Wang, Jiangbo Lin, Wenting Lin, Chao Feng, Shudong Xia, Weili Ge

“…Abstract Background Structural remodeling of the left atrial appendage (LAA) is characteristic of atrial fibrillation (AF), and LAA morphology impacts radiofrequency catheter ablation (RFCA) outcomes. …”
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A novel mechanism of sperm midpiece epididymal maturation and the role of CCDC112 in sperm midpiece formation and establishing an optimal flagella waveform by Maddison L. Graffeo, Joseph Nguyen, Farin Yazdan Parast, Jessica E. M. Dunleavy, Denis Korneev, Hongyi Yang, Hidenobu Okuda, Anne E. O’Connor, Donald F. Conrad, Reza Nosrati, Brendan J. Houston, Moira K. O’Bryan

“…Abstract Background The mitochondrial sheath is a defining feature of mammalian sperm with proposed functions in structural support and energy production for flagella movement. …”
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The FinnBrain multimodal neonatal template and atlas collection by Jetro J. Tuulari, Aylin Rosberg, Elmo P. Pulli, Niloofar Hashempour, Elena Ukharova, Kristian Lidauer, Ashmeet Jolly, Silja Luotonen, Hilyatushalihah K. Audah, Elena Vartiainen, Wajiha Bano, Ilkka Suuronen, Isabella L. C. Mariani Wigley, Vladimir S. Fonov, D. Louis Collins, Harri Merisaari, Linnea Karlsson, Hasse Karlsson, John D. Lewis

“…Abstract The accurate processing of neonatal and infant brain MRI data is crucial for developmental neuroscience but presents unique challenges that child and adult data do not. …”
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Genetic diversity of norovirus in Shenzhen Based on continuous surveillance from 2016 to 2022 by Xin Wang, Wanqiu Liu, Wanqiu Liu, Wanqiu Liu, Mingda Hu, Hui Ma, Yaqing He, Boqian Wang, Kexin Li, Kexin Li, Kexin Li, Rui Zhang, Rui Zhang, Rui Zhang, JingJing Fu, JingJing Fu, Hailong Zhang, Long Chen, Xinru Zhao, Xinru Zhao, Xinru Zhao, Buaijier Aimaiti, Buaijier Aimaiti, Buaijier Aimaiti, Hongbin Song, Hongguang Ren, Xiaofeng Hu

“…Mutations in the VP1 protein, based on the protein structure of GII.4_Sydney[P31], provided insights into the evolutionary trends of key genotypes. …”
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The mediating role of biological age in the association between dietary index for gut microbiota and sarcopenia by Jingyuan Zhang, Jun Guo, Jing Zhang, Jing Zhang, Heng Liu, Lin Zhou, Chi Cheng, Hong Cao

“…Alterations in muscle structure are closely linked to DNA methylation-based biological age assessments and individual dietary patterns. …”
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Impact of different genomic relationship matrix construction methods on the accuracy of genomic prediction in different species by Shiyi Wang, Yingjia Wei, Dengying Liu, Xiangzhe Zhang, Qishan Wang, Yuchun Pan, Peipei Ma

“…The learning curve for bull data showed the choice of G-matrix had minimal impact on prediction accuracy when the reference population size and genetic marker density reached a certain threshold.DiscussionThe study concluded that the optimal G-matrix construction method varies across species, with population structure being a key factor. …”
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SURGERY OF BRAIN STEM CAVERNOUSES MALFORMATION by V. V. Stupak, Sh. Aul, A. G. Bobylev, M. V. Kutsenko, D. A. Dentsel, T. M. Shogunbekov, V. M. Bon, A. M. Gazeev, A. E. Simonovich, S. V. Tsvetovskiy

“…Cavernous malformations (CM), also known as cavernous angiomas or cavernomas, are benign vascular hamartomas having a sinusoidal type of wall structure.CM occurs in the brain stem with a frequency of 9–35 % of cases. …”
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Distribution Characteristics of Nutrients and Eutrophication Assessment in Yueqing Bay by YAO Kaixue, YIN Rui, WANG Yang, CHEN Feng, LI Zhenhua

“…Based on the Marine environment monitoring data of Yueqing Bay in spring, summer, autumn and winter from 2018 to 2019, the spatial and temporal distribution characteristics of nutrient salts (dissolved inorganic nitrogen, DIN) and active phosphate (DIP) in the sea were analyzed, and the pollution degree, eutrophication degree and nutrient structure of the sea area were evaluated by single factor index method, eutrophication index method and potential eutrophication model. …”
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Conserved missense variant pathogenicity and correlated phenotypes across paralogous genes by Tobias Brünger, Alina Ivaniuk, Eduardo Pérez-Palma, Ludovica Montanucci, Stacey Cohen, Lacey Smith, Shridhar Parthasarathy, Ingo Helbig, Michael Nothnagel, Patrick May, Dennis Lal

“…Across ten genes encoding voltage-gated sodium channels and 22 expert-curated disorders, we identify cross-paralog correlated phenotypes based on 3D structure spatial position. For example, multiple established loss-of-function related disorders across SCN1A, SCN2A, SCN5A, and SCN8A show overlapping spatial variant clusters. …”
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Functional Analysis of <i>Penicillium expansum</i> Glucose Oxidase-Encoding Gene, <i>GOX2</i>, and Its Expression Responses to Multiple Environmental Factors by Yongcheng Yuan, Yutong Ru, Xiaohe Yuan, Shuqi Huang, Dan Yuan, Maorun Fu, Wenxiao Jiao

“…It is either an integrated membrane protein (such as a receptor or channel) that is directly anchored to the membrane through a transmembrane structure or a non-classical secreted protein that is secreted extracellularly. …”
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