Do P2Y12 receptor inhibitors prescribed poststroke modify the risk of cognitive disorder or dementia? Protocol for a target trial using multiple national Swedish registries by John Attia, Michael Nilsson, Frederick R Walker, Christopher Oldmeadow, Michael Pollack, Jenny Nyberg, Sara Gustavsson, N David Åberg, Georg Hans Kuhn, Madeleine Hinwood, Marina Ilicic, Chris Levi, Sarah J Johnson, Leeanne M Carey, Lucy Leigh, Neil Spratt, Thomas Lindén

“…We developed a study protocol following the components of the target trial approach described by Hernan et al and describe the data structure that would be required in order to make a causal inference. …”
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Rare ginsenosides: A unique perspective of ginseng research by Wenxiang Fan, Linhong Fan, Ziying Wang, Yuqi Mei, Longchan Liu, Linnan Li, Li Yang, Zhengtao Wang

“…Aim of review: In this review, recent advances of Rare ginsenosides (RGs) were summarized dealing with the structurally diverse characteristics, traditional usage, drug discovery situation, clinical application, pharmacological effects and the underlying mechanisms, structure–activity relationship, toxicity, the stereochemistry properties, and production strategies. …”
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The current induced mass transformation of Ag alloy wire bonded led chip by Xiaohong Yuan, Qinlian He, Shanju Zheng, Jiaheng Zhang, Dapeng Yang, Qinsong Bi, Yuxi Luo, Dengquan Chen, Xiaojing Wang

“…This leads to polarity differences in interconnection structure, underscoring the urgent need to clarify the evolution of microscale bonding interfaces. …”
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Research on the supply risk propagation in the global iron ore trade network by Chao Liu, Chao Liu, Chao Liu, Chao Liu, Ting Zhao, Ting Zhao, Ting Zhao, Ting Zhao, Gaoshang Wang, Gaoshang Wang, Gaoshang Wang, Gaoshang Wang, Shengqian Liu, Shengqian Liu, Shengqian Liu, Shengqian Liu

“…Key findings include: ⅰ:The iron ore trade system exhibits a centralized structure dominated by China, Australia, and Brazil, resulting in elevated supply risks. …”
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Reliable Multistate RRAM Devices for Reconfigurable CAM and IMC Applications by Shengpeng Xing, Zijian Wang, Zhen Wang, Pengtao Li, Xuemeng Fan, Ziyang Zhang, Guobin Zhang, Jianhao Kan, Qi Luo, Shuai Zhong, Yishu Zhang

“…This work presents a reliable multistate RRAM device based on a Cu/Ta2O5/WO<inline-formula> <tex-math notation="LaTeX">${}_{\text {3-x}}$ </tex-math></inline-formula>/Pt structure, utilizing fully CMOS-compatible materials. …”
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Global quantitative proteome analysis of a multi-resistant Klebsiella pneumoniae strain by Marie-Sofie Illenseher, Marie-Sofie Illenseher, Christian Hentschker, Manuela Gesell Salazar, Larissa Milena Busch, Lisa Zierke, Alexander Reder, Stephan Michalik, Uwe Völker, Sven Hammerschmidt, Kristin Surmann

“…Approximately one-third of the assigned OMPs were lipoproteins, i.e., proteins that represent important fitness factors and might be immunogenic due to their structure and position in the bacterial cell membrane. …”
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Assessing the knowledge, attitudes, and perceptions of ovarian cryopreservation technology among women with ovarian diseases by Faten Mabrouk Nouh, Faten Mabrouk Nouh, Hasan Abualruz, Amal Khalifa Khalil, Rania Ezzat El-Gobashy, A. M. F. Alasser, Aya Ibrahim Shaban Abdullah, Jebril Al Hrinat, Aseel Ghaleb Hendi, Majdi AL-Zoubi, Tahani Al Rahbeni, Khalid Al-Mugheed, Sally Mohammed Farghaly Abdelaliem, Hanaa Elsayed Ahmed Shahin, Hanaa Elsayed Ahmed Shahin

“…Participants were recruited from outpatient obstetrics and gynecology clinics at the Menoufia University Hospital and Shebin El-Kom Teaching Hospital. Data collection instruments included an online questionnaire, obstetric and gynecological history forms, and structured assessments of knowledge, perceptions, and attitudes toward oocyte cryopreservation.ResultsThe findings revealed that 59.9% of the women had a moderate level of knowledge regarding oocyte cryopreservation. …”
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Cytological Characterization of <i>vrnp 1</i>, a Pollen-Free Male Sterile Mutant in Mung Bean (<i>Vigna radiata</i>) by Yuxin Cheng, Tianjiao Lan, Kunpeng Deng, Minghai Wang, Shuying Bao, Dan Han, Yapeng Xu, Han Wang, Ning Xu, Zhongxiao Guo

“…Mung bean (<i>Vigna radiata</i>) plays a significant role in agricultural trade, food processing and utilization, and cropping structure adjustment due to its abundant nutritional components, medicine-food homology, capacity for nitrogen fixation, and soil improvement. …”
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Diffusion Bubble Model: A novel MRI approach for detection and subtyping of neonatal punctate white matter lesions by Erjun Zhang, Benjamin De Leener, Gregory A. Lodygensky

“…Diffusion magnetic resonance imaging, particularly diffusion tensor imaging (DTI), is an indispensable non-invasive tool for visualizing brain structure and detecting injuries by tracking water molecule motion. …”
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Comprehensive genome-wide analysis of the GmFRIGIDA gene family in soybean: identification, characterization, and expression dynamics by Song Yu, Yuxuan Wang, Yuxuan Wang, Wenwen Ren, Wenwen Ren, Yisheng Fang, Leili Wang, Yifei Zhang, Chengyang Song, Xiao Luo

“…Our findings indicate that eight GmFRLs arose from whole-genome duplication (WGD) events, alongside two tandem duplication events. Gene structure analysis confirmed that all GmFRL members contain Frigida domains. …”
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Machine learning assisted design and preparation of Fe85Si2B8.5P3.5C1 amorphous/nanocrystalline alloy with high Bs and low Hc by Shengdong Tang, Rui Sun, Yifan He, Guichang Liu, Ruixuan Wang, Yuqin Liu, Chengying Tang

“…X-ray diffraction (XRD), differential scanning calorimetry (DSC), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), B–H loop tracer, and magnetostriction instrument were used to identify the phase structure and physical properties of the Fe85Si2B8.5P3.5C1 alloy. …”
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Ionospheric Scintillation and Geomagnetic Disturbance Caused by Space Hurricanes by Sheng Lu, Zan‐Yang Xing, Qing‐He Zhang, Yong‐Liang Zhang, Hui‐Gen Yang, Kjellmar Oksavik, L. R. Lyons, Kazuo Shiokawa, Yong Wang, Yu‐Zhang Ma, Xiang‐Yu Wang, Tong Xu, Shu‐Ji Sun, Duan Zhang

“…Abstract A space hurricane is a large‐scale, cyclone‐shaped aurora characterized by a rotating magnetic structure and shears in plasma convection, driven by high‐latitude magnetic reconnection. …”
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Innovations in the treatment and prevention of influenza in children and adolescents by Yu. V. Lobzin, A. V. Gorelov, K. V. Zhdanov, D. A. Lioznov, I. V. Babachenko, A. S. Dmitriev, E. A. Dondurey, V. V. Krasnov, L. N. Mazankova, A. P. Prodeus, A. Yu. Rtishсhev, S. V. Rychkova, E. V. Sidorenkova, Kh. S. Khaertynov, E. V. Esaulenko

“…This makes it the medicine of choice, especially in cases of high risk of complicated influenza infection.Given the high importance of influenza in the structure of childhood morbidity, it is crucial to continue improving methods of prevention, diagnosis, and treatment of this disease, especially in children.…”
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Risk perception of severity or death from COVID-19: a systematic review of the factors associated by Rander Junior Rosa, Rubia Laine de Paula Andrade, Letícia Perticarrara Ferezin, Mônica Chiodi Toscano de Campos, Mônica Chiodi Toscano de Campos, Heriederson Sávio Dias Moura, Thais Zamboni Berra, Natacha Martins Ribeiro, Titilade Kehinde Ayandeyi Teibo, André Luiz Teixeira Vinci, Felipe Mendes Delpino, Miguel Ángel Fuentealba Torres, Ricardo Alexandre Arcêncio

“…Two reviewers independently selected articles, with disagreements resolved by a third reviewer. The data were extracted using a structured form, and the findings were synthesized narratively. …”
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ReactorAFM/STM – dynamic reactions on surfaces at elevated temperature and atmospheric pressure by Tycho Roorda, Hamed Achour, Matthijs A. van Spronsen, Marta E. Cañas-Ventura, Sander B. Roobol, Willem Onderwaater, Mirthe Bergman, Peter van der Tuijn, Gertjan van Baarle, Johan W. Bakker, Joost W. M. Frenken, Irene M. N. Groot

“…Here we show current developments of the ReactorAFM/STM, implementing a qPlus sensor to add the ability of combining atomic force microscopy (AFM) and scanning tunneling microscopy (STM) techniques to study the geometric and electronic structure of materials under reaction conditions. We demonstrate this by imaging a Pd(100) single crystal at 450 K with combined AFM/STM. …”
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Measurement of purpose in life among Arabic-speaking adolescents: psychometric properties of an Arabic-language version of the Claremont purpose scale (CPS) by Amir Noureddine, Souheil Hallit, Souheil Hallit, Souheil Hallit, Diana Malaeb, Fouad Sakr, Mariam Dabbous, Tylor Cosgrove, Sahar Obeid, Feten Fekih-Romdhane, Feten Fekih-Romdhane, Ahmed A. Moustafa, Ahmed A. Moustafa

“…Lebanese adolescents aged 14 to 18 years (N = 793, 62.4% females, mean age of 16.08 ± 1.74 years) were recruited using an online questionnaire and a snowball sampling technique.ResultsThe fit of the three-factor structure of CPS scores was satisfactory as indicated by the Confirmatory Factor Analysis. …”
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A Comprehensive Evaluation of a Coumarin Derivative and Its Corresponding Palladium Complex as Potential Therapeutic Agents in the Treatment of Gynecological Cancers: Synthesis, Ch... by Mirela Jevtić, Marijana Stanojević Pirković, Teodora Komazec, Marija Mojić, Sanja Mijatović, Danijela Maksimović-Ivanić, Dušan Dimić, Zoran Marković, Dušica Simijonović, Dejan Milenković, Edina Avdović

“…<b>Results:</b> A low mean absolute error between experimental and theoretical data proved that the optimized structure corresponded to the experimental one. …”
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Annual cycle variations in the gut microbiota of migratory black-necked cranes by Yujia Zhang, Ruifeng Ma, Suolangduoerji, Shujuan Ma, Shujuan Ma, Akebota Nuertai, Ke He, Hongyi Liu, Ying Zhu

“…Despite having greater diversity, the summer gut microbiota had a simpler network structure than the other seasons (fewer edges and nodes). …”
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Empirical evidence for a process-based model of health-related quality of life using network analysis by Nicolette Stogios, Nicolette Stogios, Troy Francis, Troy Francis, Rachel G. Peiris, Aleksandra Stanimirovic, Aleksandra Stanimirovic, Valeria Rac, Valeria Rac, Robert P. Nolan, Robert P. Nolan

“…While contemporary assessments are structured to evaluate an individual's HRQL state, we propose a complementary process-based model, which is defined as an appraisal that evolves over time as it reflects and informs a self-regulatory process of adapting to dynamic changes in bio-psycho-social life domains. …”
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Integration of ATAC-seq and RNA-seq reveals signal regulation during post-molt and inter-molt stages in muscle of Eriocheir sinensis by Bin Wang, Bin Wang, Jingjing Li, Mingzhi Zhang, Mingzhi Zhang, Anqi Li, Zhentao Song, Zhentao Song, Zhen He, Zhen He, Ruiqi Zhang, Ruiqi Zhang, Tong Hao, Tong Hao, Jinsheng Sun, Jinsheng Sun

“…In all the enriched signaling pathways, GPCR signaling pathway includes the most differentially expressed genes (8 genes), which underlines its importance in the signal transduction from the post-molt stage to the inter-molt stage. Further protein structure analysis and RT-qPCR validation confirmed five GPCR genes related to molting process, in which four genes (GRM7, FMRFaR, mth2, gpr161) are active during the post-molt stage and one gene (moody) functions during the inter-molt stage.DiscussionThese findings highlight the key regulatory proteins and pathways involved in E. sinensis muscle during molting and also offer foundational data for studying the mechanisms of molting and discontinuous growth in crustaceans.…”
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