Risk Factors and Prognostic Implications of Tumor‐Related Epilepsy in Diffuse Glioma Patients: A Real‐World Multicenter Study by Yao Xiao, Zhuang Nie, Jinsha Huang, Jie Zhao, Chengjun Dong, Yan Zou, Zikai Li, Bingqing Yan, Yue Hu, Fan Yang, Jong Woo Lee, Alexander P. Lin, Steven Tobochnik, Min Zhou, Ziqiao Lei

“…Multivariate analysis identified age as the only significant independent correlate of TRE in the OD/AC group (OR = 0.961; p = 0.004), while the absence of deep structure involvement was independently associated with TRE in the NOS/NEC and HGG groups. …”
Get full text

The PA-X host shutoff site 100 V exerts a contrary effect on viral fitness of the highly pathogenic H7N9 influenza A virus in mice and chickens by Xia Chen, Ming Kong, Chunxi Ma, Manyu Zhang, Zenglei Hu, Min Gu, Xiaoquan Wang, Ruyi Gao, Shunlin Hu, Yu Chen, Xiaowen Liu, Daxin Peng, Xiufan Liu, Jiao Hu

“…By analysing the polymorphism of this residue in various subtype viruses, we found that PA-X 100 was highly variable in H7N9 viruses. Structural analysis revealed that 100 V was generally close to the PA-X endonuclease active site, which may account for its host shutoff activity. …”
Get full text

Do neonatal intensive care unit (NICU) health workers know about retinopathy of prematurity (ROP)? A qualitative study at a Regional Referral Hospital in Uganda by Henry Muwonge, Innocent Ayesiga, Primrose Magala, Tom Didimus Ediamu, Hana El Diwany, Ian LY Yeung, Alex Wasomoka, Phillip Musoke, Elias Musiime, Abraham Tumwesigye, Pius Atwau, Noreen Atwijukire, Iddi Ndyabawe, Anne Mpaire Musika, Himanshu I Patel, Aeesha NJ Malik, Ibrahim Bwaga, Sheba Gitta Nakacubo

“…We recommend developing a formal training structure and syllabus for ROP screening. The training can enhance task shifting among health workers in areas without specialised health workers. …”
Get full text

A 1.8 m Class Pathfinder Raman LIDAR for the Northern Site of the Cherenkov Telescope Array Observatory—Performance by Pedro José Bauzá-Ruiz, Oscar Blanch, Paolo G. Calisse, Anna Campoy-Ordaz, Sidika Merve Çolak, Michele Doro, Lluis Font, Markus Gaug, Roger Grau, Darko Kolar, Camilla Maggio, Manel Martinez, Samo Stanič, Santiago Ubach, Marko Zavrtanik, Miha Živec

“…The results show that the pBRL can provide valuable scientific results on aerosol characteristics and structure, although not all performance requirements could be validated under the conditions found at the two test sites. …”
Get full text

Butyrate alleviates food allergy by improving intestinal barrier integrity through suppressing oxidative stress‐mediated Notch signaling by Jialu Shi, Wenjun Mao, Yuqing Song, Yuxin Wang, Lili Zhang, Yan Xu, Huiwen Gu, Siyu Yao, Yuanhang Yao, Zhifeng Liu, Vijaya Raghavan, Jin Wang

“…However, butyrate counteracted this loop by restoring microbiota structure and suppressing reactive oxygen species (ROS)/Notch cascades. …”
Get full text

Outdoor Air Pollution Is Related to Amygdala Subregion Volume and Apportionment in Early Adolescence by Jessica Morrel, L. Nate Overholtzer, Kirthana Sukumaran, Devyn L. Cotter, Carlos Cardenas-Iniguez, J. Michael Tyszka, Joel Schwartz, Daniel A. Hackman, Jiu-Chiuan Chen, Megan M. Herting

“…Background: Outdoor air pollution exposure is associated with structural and functional brain differences and an increased risk for psychopathology. …”
Get full text

Identification, Characterization, Expression Profiling and Functional Analysis of Tobacco <i>CalS</i> Gene Family by Hong Wang, He Meng, Xiaohan Qi, Yi Pan, Bailu Ji, Liuying Wen, Yanjun Zan, Huan Si, Yuanying Wang, Dan Liu, Aiguo Yang, Zhengwen Liu, Lirui Cheng

“…A comprehensive analysis of their physicochemical properties, gene structure, and evolutionary history highlighted their evolutionary conservation. …”
Get full text

Lupus nephritis and U1-RNP-antibodies are associated with low bone mineral density and osteoporosis in patients with systemic lupus erythematosus: baseline findings in a sub-cohort... by Edgar Wiebe, Elisa Celine Schilling, Dörte Huscher, Andriko Palmowski, Zhivana Boyadzhieva, Sandra Hermann, Burkhard Muche, Mirella Lopez Picazo, Gerhard Krönke, Falk Hiepe, Tobias Alexander, Frank Buttgereit

“…Our findings suggest that 3D bone structure analysis may be helpful in discriminating past vertebral fractures. …”
Get full text

Microstructure changes of the brain preceded glymphatic function changes in young obesity with and without food addiction by Meizhi Yi, Zeng Yule, Weijia Song, Tianyao Wang, Luokai Zhang, Can Hu, Yifeng Peng, Zhaoxiang Zhang, Liangwu Chen, Yan Wang, Huiting Wu, Zhaojie Peng, Xinhua Xiao, Jun Liu, Hong Zhou

“…We also explored the relationships among the WM structural alterations, cerebral lymphatic functional changes, BMI, emotional status, sleep quality and cognitive decline in the participants. …”
Get full text

大學教師學術發表影響力之影響因素 Factors Influencing Publication Impact of Faculty by 郭玲玲 Ling-Ling Kueh, 許清芳 Ching-Fan Sheu

“…Additionally, given the hierarchical structure of educational data, this study employed generalized linear mixed-effect model tree analysis to examine data with nested and clustered properties. …”
Get full text

Standardization of epistemic trust/mistrust/credulity questionnaire: Examining validity and reliability among adolescents Standardization of ETMCQ among adolescents by Raziyeh Hashemi, Mehdi Reza Sarafraz, Habib Hadian Fard, Mohammad Reza Taghavi

“…Examining the three-factor structure of the Epistemic Trust Questionnaire, confirmatory factor analysis was performed, with results shown in the table below.The value of X2/df and RMSEA indices are 86.2 and 0.078 respectively. …”
Get full text

Examining the effect of knowledge-based leadership on organizational innovation with the mediating role of illusion of control and rationality by davar Dirmina, Gholamhasan Shirdel, Seyyed Javad Iranban

“…The statistical method used in this study was the structural modeling method based on the partial least squares approach and Smart PLS3 software. …”
Get full text

Index System and Evaluation Method of Geological Environment Suitability for Human Health by Xingchun JIAO, Zhaohe ZHANG, Wei FANG, Ruimin LI, Jiuchen LIU, Wenbin JIA

“…Geological background characteristics, including tectonic structure, lithologic features, and landform configuration shape the living conditions of human being. …”
Get full text

Components of stakeholder participation to create value in the banking industry in East Azerbaijan Agricultural Bank by Alireza Tagavi, Alireza Bafandeh Zendeh, Samad Aali

“…This research is developmental in terms of the goal, descriptive-exploratory in terms of the type of method, qualitative in terms of the method of collecting data, and meta-synthesis approach in terms of the method of conducting the research. …”
Get full text

Intensification of Natural Disasters in the State of Pará and the Triggering Mechanisms Across the Eastern Amazon by Everaldo B. de Souza, Douglas B. S. Ferreira, Luciano J. S. Anjos, Alan C. Cunha, João Athaydes Silva, Eliane C. Coutinho, Adriano M. L. Sousa, Paulo J. O. P. Souza, Waleria P. Monteiro Correa, Thaiane S. Silva Dias, Alexandre M. C. do Carmo, Carlos B. B. Gutierrez, Giordani R. C. Sodré, Aline M. M. Lima, Edson J. P. Rocha, Bergson C. Moraes, Luciano P. Pezzi, Tercio Ambrizzi

“…Based on statistical analyses applied to official data from the Digital Atlas of Disasters in Brazil over the last 25 years, we evidenced a consistent intensification in the annual occurrence of natural disasters in the state of Pará, located in the eastern Brazilian Amazon. …”
Get full text

A Multiwavelength Portrait of the 3C 220.3 Lensed System by Sóley Ó. Hyman, Belinda J. Wilkes, S. P. Willner, Joanna Kuraszkiewicz, Mojegan Azadi, D. M. Worrall, Adi Foord, Simona Vegetti, Matthew L. N. Ashby, Mark Birkinshaw, Christopher Fassnacht, Martin Haas, Daniel Stern

“…New three-color Hubble Space Telescope (HST) data reveal a full Einstein ring and allow a more precise lens model. …”
Get full text

PIEZO1 mechanical insensitivity in generalized lymphatic dysplasia with the potential for pharmacological rescue by Melanie J. Ludlow, Oleksandr V. Povstyan, Deborah M. Linley, Silvia Martin-Almedina, Charlotte Revill, Kevin Cuthbertson, Katie A. Smith, Emily Fay, Elisavet Fotiou, Andrew Bush, Claire Hogg, Tobias Linden, Natalie B. Tan, Susan M. White, Juan C. Del Rey Jimenez, Ege Sackey, Esther Dempsey, Sahar Mansour, Gregory Parsonage, Antreas C. Kalli, Richard Foster, Pia Ostergaard, David J. Beech

“…Two of the variants encode amino acid changes in the channel’s cap structure (Ile2270Thr and Arg2335Gln), one in the ninth transmembrane helical unit (THU) below the cap (Gly1978Asp) and one in the fifth THU distant from the cap (Glu829Val). …”
Get full text

Deep learning-based carotid plaque vulnerability classification with multicentre contrast-enhanced ultrasound video: a comparative diagnostic study by Yanli Guo, Hongxia Zhang, Yang Guang, Wen He, Bin Ning, Chen Yin, Mingchang Zhao, Fang Nie, Pintong Huang, Rui-Fang Zhang, Qiang Yong, Jianjun Yuan, Yicheng Wang, Lijun Yuan, Litao Ruan, Tengfei Yu, Haiman Song, Yukang Zhang

“…Moreover, with a more powerful network structure and better utilisation of video information, DL-DCCP provided greater diagnostic accuracy than a state-of-the-art static CNN model.Trial registration number ChiCTR1900021846,…”
Get full text

A Multifaceted Computational Approach to Identify PAD4 Inhibitors for the Treatment of Rheumatoid Arthritis (RA) by Mansour S. Alturki, Mohamed S. Gomaa, Nada Tawfeeq, Abdulaziz H. Al Khzem, Mohsina B. Shaik, Murtadha Alshaikh Jafar, Mohammad Alsamen, Hasan Al Nahab, Mohammad Al-Eid, Alhassan Almutawah, Thankhoe A. Rants’o, Khaled A. G. Ayil, Mohammed Almaghrabi

“…Methods: We utilized Maestro Schrödinger as a computational tool for preparing and docking simulations on the PAD 4 enzyme crystal structure that is retrieved from RCSB Protein Data Bank (PDB ID: 4X8G) while the docked FDA-approved medications are obtained from the Zinc 15 database. …”
Get full text

Bidirectional associations among positive affect, anhedonia and meaning in life during major depressive episode: ecological momentary assessment study in unipolar and bipolar indiv... by Heidi Ka Ying Lo, Roger S. McIntyre, Iris Wai Tung Tsui, Fiona Yan Yee Ho, Ting Kin Ng, Corine Sau Man Wong, Suet Ying Yuen, Chit Tat Lee, Chun Yin Poon, Inez Myin-Germeys, Ka Fai Chung

“…Multilevel modelling analysis was conducted, with estimation of first-order autoregressive model structure and time-lagged relationship between pleasure and positive affect. …”
Get full text