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51961
New possibilities of using perampanel in children. Efficacy and tolerability of perampanel in the treatment of epilepsy (literature review and experience of Svt. Luka’s Association...
Published 2024-11-01“…This study included 270 patients aged 4 to 43 years (125 males and 145 females; 255 children and adolescents aged 4–18 years; 15 adult patients; mean age at the time of perampanel therapy initiation was 11.8 years) who received perampanel and for whom we managed to collect clinical data for at least 6 months.The study sample included 114 patients with structural and presumably structural focal epilepsy, 120 patients with genetic and presumably genetic epilepsy (including Dravet and Angelman syndromes, Lafora disease, mutations in genes PCDH19, PHACTR1, CDKL5, ARX, PING, SCN2A, KIAA2022, chromosomal microdeletions, etc.), and 36 patients with focal epilepsy of unknown etiology. …”
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51962
Neural correlates of device-based sleep characteristics in adolescents
Published 2025-05-01“…These biotypes also differ in cognitive performance and brain structure and function. Longitudinal analysis confirms these differences from ages 9 to 14, with biotype 3 showing consistent cognitive advantages. …”
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51963
Different Fish Farming Patterns in Paddy Fields Substantially Impact the Bacterial Community Composition, Stability, and Assembly Processes in Paddy Water
Published 2024-12-01“…Hence, partitioned rice–fish farming is a feasible and good agricultural production pattern, and from the perspectives of bacterial community diversity and stability it offers both theoretical insights and data-supported foundations for advancing sustainable agricultural practices.…”
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51964
Integration of nontarget screening and QSAR modeling to identify novel butachlor transformation products of high priority in soil and water environment
Published 2025-05-01“…Butachlor (BTR), a widely used chloroacetanilide herbicide in rice paddies worldwide, has raised concerns due to limited data on its environmental transformation products (TPs) and their ecotoxicological effects. …”
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51965
Clouds Detection in Polar Icy Terrains: A Deformable Attention-Based Deep Neural Network for Multispectral Polar Scene Parsing
Published 2025-01-01“…DLACD-Net incorporates a nested U-shaped encoder–decoder structure and proposes DSACRSU at each encoding–decoding stage. …”
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51966
Drought-induced shifts in cowpea rhizoplane bacterial communities across different vegetative and reproductive stages
Published 2025-09-01“…Beta diversity results revealed that genotype and drought significantly influenced microbial community structure across growth stages. Proteobacteria dominated the root zone of the EpicSelect4 genotype, while UCR369 showed an increase in Actinobacteria under drought conditions. …”
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51967
Isobutyrate Confers Resistance to Inflammatory Bowel Disease through Host–Microbiota Interactions in Pigs
Published 2025-01-01“…However, the therapeutic effects and mechanisms of action of isobutyrate in IBD remain unclear. Clinical data indicate that the fecal levels of isobutyrate are markedly lower in patients with Crohn’s disease than in healthy controls. …”
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51968
Tick-borne encephalitis virus seroprevalence and infection incidence in Switzerland, 2020–2021
Published 2025-03-01“…Questionnaire data were used to determine vaccination status and risk factors. …”
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51969
Barriers and facilitators to accessing healthcare services among elderly people living in a rural Amazonian community, Brazil
Published 2025-07-01“…The outcome was utilisation of medical services in the public health system in the last 12 months. Structural equation modelling was guided by Andersen’s behavioural model. …”
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51970
Uncovering the impact of multiple determinants on vegetation NPP in Inner Mongolia
Published 2024-12-01“…Focusing on Inner Mongolia, the primary factors influencing grassland growth were systematically analyzed using Geodetector and structural equation modeling, leveraging multi-source remote sensing data and statistical information. …”
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51971
Preliminary Analysis of a Novel Spaceborne Pseudo Tripe-Frequency Radar Observations on Cloud and Precipitation: EarthCARE CPR-GPM DPR Coincidence Dataset
Published 2025-07-01“…By integrating EarthCARE W-band doppler cloud radar observations with GPM Ku/Ka-band dual-frequency precipitation radar data, this study constructs a novel global “pseudo tripe-frequency” radar coincidence dataset comprising 2886 coincidence events (about one-third of the events detected precipitation), aiming to systematically investigating band-dependent responses to cloud and precipitation structure. …”
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51972
Analysis of the dynamics of occupational morbidity and its consequences in Ukraine in comparison with other countries of the world
Published 2023-09-01“…The most common occupational diseases in Ukraine are diseases caused by dust exposure: pneumoconiosis, chronic bronchitis, COPD, which make up 39% of the occupational morbidity structure. The global indicator of Disability Adjusted Life Year (DALYs) from the occupational exposure factors in the world (5.1%) is 3 times higher than the similar one in Ukraine (1.53%). …”
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51973
Genetic aspects of nonimmune hydrops fetalis
Published 2024-12-01“…The prevalence of nonimmune hydrops fetalis, according to various data, ranges from 0.05 to 0.5%, or about 1:4000 live births. …”
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51974
Women’s and girls’ sexual empowerment differs by geographical context: a population-based validation study
Published 2025-07-01“…Findings Final models confirm the theoretical structure of the sexual empowerment measure, including two- dimensions: “existence of choice” and “exercise of choice”, each comprised of three items, with moderate internal consistency ranging from 0.59 to 0.69. …”
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51975
Genomic signal selection analysis reveals genes related to the lambing trait of Hotan sheep
Published 2025-07-01“…To identify the population genetic structure and linkage disequilibrium associated with SLE and TLE traits, we employed two complementary genome selection signals: the interpopulation genetic differentiation index (FST) and nucleotide diversity. …”
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51976
A comparative analysis of imaging-based algorithms for detecting focal cortical dysplasia type II in children
Published 2025-08-01“…Three imaging-based detection algorithms were applied to T1-weighted images, each targeting key structural features: cortical thickness, gray matter intensity (extension), and gray–white matter junction blurring. …”
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51977
Patterns of blue and green water in the Yellow River Basin from 1998 to 2020: Influence of climate change and human activity
Published 2025-06-01“…Furthermore, the Partial Least Squares Structural Equation Modeling (PLS-SEM) method is used to quantify the respective contributions of climate change and human activities to these observed patterns. …”
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51978
Physicians’ perspectives on COVID-19 vaccinations for children: a qualitative exploration in Ontario, Canada
Published 2024-07-01“…We explored physicians’ experiences providing COVID-19 vaccination recommendations to parents and their reflections on the contextual factors that shaped these experiences.Design We conducted an interpretive qualitative study using in-depth interviews. We analyzed the data using reflexive thematic analysis and a socioecological framework.Setting This study involved primary care practices associated with The Applied Research Group for Kids (TARGet Kids!) …”
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51979
Slope—sedimentary source rock-type helium enrichment model: a case study of Shenmu Gas Field, Ordos Basin
Published 2024-11-01“…The enrichment of helium in these gas fields is often closely related to the development of faults. However, the structural background within the basin is complex. To study the characteristics and controlling factors of helium enrichment under different geological backgrounds within the basin, an analysis of natural gas composition was conducted in the northeastern Yishan Slope of the Ordos Basin. …”
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51980
Investigation of the Velocities of Coals of Diverse Rank under Water- or Gas-Saturated Conditions for Application in Coalbed Methane Recovery
Published 2019-01-01“…The discrete velocity ratio data were fit as negative linear correlations with UPVs, and different coals had different declining degrees, the difference of which might be attributed to the characteristics of structural cracks and the inherent properties of the coal, such as grain size and pore shape, which result in decreasing coal integrity and strength. …”
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