SVLearn: a dual-reference machine learning approach enables accurate cross-species genotyping of structural variants by Qimeng Yang, Jianfeng Sun, Xinyu Wang, Jiong Wang, Quanzhong Liu, Jinlong Ru, Xin Zhang, Sizhe Wang, Ran Hao, Peipei Bian, Xuelei Dai, Mian Gong, Zhuangbiao Zhang, Ao Wang, Fengting Bai, Ran Li, Yudong Cai, Yu Jiang

“…Abstract Structural variations (SVs) are diverse forms of genetic alterations and drive a wide range of human diseases. …”
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A specialized reference panel with structural variants integration for improving genotype imputation in Alzheimer disease and related dementias by Po-Liang Cheng, Hui Wang, Beth A. Dombroski, John J. Farrell, Iris Horng, Tingting Chung, Giuseppe Tosto, Brian W. Kunkle, William S. Bush, Badri Vardarajan, Gerard D. Schellenberg, Wan-Ping Lee

“…Recognizing the importance of associations between structural variants (SVs) and AD and their underrepresentation in existing public reference panels, our panel uniquely integrates single-nucleotide variants (SNVs), short insertions or deletions (indels), and SVs. …”
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Quantitative and structural features of the SMN1 and SMN2 genes in patients with spinal muscular atrophy 5q by A. I. Vlasenko, V. D. Nazarov, S. V. Lapin, A. V. Mazing, E. A. Surkova, T. V. Blinova, T. M. Alekseeva

“…Description of quantitative and structural features of the SMN1 and SMN2 genes in patients with SMA 5q.Materials and methods. …”
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The mediating role of daily living ability and sleep in depression and cognitive function based on a structural equation model by Liu Huijun, Zhang Xiange, Yang Ming, Sun Jiayi, Peng Juanjuan, Xu Wangquan, Song Yueli, Fang Guixia

“…Pearson correlation analysis was employed to test the relationship between depression symptoms, cognition, poor sleep quality and daily living ability of the elderly. The structural equation model was used to explore the link between depression and cognition in the older adults, and to test mediating effects of daily activity and sleep disturbance on depression and cognition. …”
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Cardiovascular risk burden, dementia risk and brain structural imaging markers: a study from UK Biobank by Ting Li, Jing Chen, Yan Zheng, Klodian Dhana, Geng Zong, Yuan Ma, Trudy Voortman, Wei Gan, Yaying Cao, Yonghua Hu, Changzheng Yuan, Jie Shen, Gaohong Zhu, Chengwu Feng

“…Background Cardiovascular risk burden is associated with dementia risk and neurodegeneration-related brain structure, while the role of genetics and incident cardiovascular disease (CVD) remains unclear.Aims To examine the association of overall cardiovascular risk burden with the risk of major dementia subtypes and volumes of related brain regions in a large sample, and to explore the role of genetics and CVD onset.Methods A prospective study among 354 654 participants free of CVD and dementia (2006–2010, mean age 56.4 years) was conducted within the UK Biobank, with brain magnetic resonance imaging (MRI) measurement available for 15 104 participants since 2014. …”
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Exploring effector-host interactions in Pyricularia oryzae infections: A molecular and structural approach to rice blast resistance by Zakir Amin, F.A. Mohiddin, Ali Anwar, Asif B. Shikari, Sajad Un Nabi, Tauseef A. Bhat, Vishal Gupta, Fehim Jeelani Wani, Shugufta Parveen, Mohd Salim Mir, Subaya Manzoor, Suhail Ashraf, Mohammad Raish

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Radiomics prediction of MGMT promoter methylation in adult diffuse gliomas: a combination of structural MRI, DCE, and DTI by Yuying Liu, Yuying Liu, Zhengyang Zhu, Jianan Zhou, Han Wang, Huiquan Yang, Jinfeng Yin, Yitong Wang, Xin Li, Futao Chen, Qian Li, Zhuoru Jiang, Xi Wu, Danni Ge, Yi Zhang, Xin Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang, Bing Zhang

“…PurposeTo assess the predictive value of radiomics features extracted from structural MRI, dynamic contrast enhanced (DCE), and diffusion tensor imaging (DTI) in detecting O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation in patients with diffuse gliomas.MethodsRetrospective MRI data of 110 patients were enrolled in this study. …”
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An in-depth exploration of four heterogeneity structure-based EGFR mutation subgroups in Chinese non-small cell lung cancer by Yongfeng Yu, Fei Yao, Jin Wang, Zhan Huang, Tao Hu, Changbin Zhu, Shun Lu

“…Abstract Background EGFR mutations have been classified into four functional subgroups (Classical-like, P-loop and αC-helical compressing (PACC), T790M-like, and exon 20 loop insertions) based on their influence on EGFR protein structure, as well as response to various types of EGFR-tyrosine kinase inhibitors (TKIs). …”
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Risk factors for anastomotic structural malhealing after laparoscopic intersphincteric resection for rectal cancer and its impact on prognosis by Hu Gang, Liu Junguang, Li Bo, Wang Yuhan, Qiu Wenlong, Mei Shiwen, Quan Jichuan, Zhuang Meng, Tang Jianqiang

“…[Objectives] To investigate the risk factors for anastomotic structural malhealing after laparoscopic intersphincteric resection (lap-ISR) for rectal cancer and its impact on patient prognosis. …”
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The Current Status of Medical Parasitology in Iran: Developing a Roadmap, Structural Mapping, and Proposed Scenarios for the Future of this Field by Seyed Mahmoud Sadjjadi, Mehdi Mohebali, Iraj Sharifi, Abdolhossein Dalimi Asl, Ali Haghighi, Abdollah Rafiei, Mostafa Rezaeian, Gholamhossein Edrissian, Hossein Keshavarz Valian, Mohammad Bagher Rokni, Mohammad Fallah, Hossein Yousefi Darani, Elham Razmjoo, Mehrzad Saraei, Ali Haniloo, Hossein Hooshyar, Ali Ehsan Heidari, Shirzad Gholami, Mahmoud Mahami Oskouei, Farnaz Kheirandish, Tahereh Mohammadzadeh, Yosef Sharifi

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Mechanism of fumonisin B1 on growth performance and intestinal structural integrity of juvenile grass carp (Ctenopharyngodon idella) by Daiyu Chen, Weidan Jiang, Pei Wu, Yang Liu, Hongmei Ren, Xiaowan Jin, Xiaoqiu Zhou, Lin Feng

“…Furthermore, increased levels of intestinal sphinganine (Sa), sphingosine (So), and FB1 residues were observed, along with disruptions in intestinal tissue structure and elevated serum D-lactic acid levels (P < 0.05). …”
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Mechanical behavior and mechanisms of superplastic deformation of aluminum alloys exhibiting the effect of structural superplasticity in solid and in solid−liquid states by В.П. Пойда, А.В. Пойда, Д.Є. Мила

“…The article presents the results of research aimed at summarizing experimental data on the mechanical behavior, structural state and mechanisms of superplastic deformation of aluminum alloys Al-4 wt.% Ge, Al-4.1 wt.% Cu-0,5 wt.% Zr, 1420T, 1933. …”
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Ground Motion Recording-Based Validation of Capacity Curves for High-Rise Reinforced Concrete Structures in Romania Constructed Before 1977 by Florin Pavel

“…Finally, updated capacity curves for high-rise residential structures constructed before 1977 are proposed by combining the analytical results with the earthquake data.…”
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Collected data on bending, vibration, and push-out tests of shallow steel-timber composite beams—Nordic systemZenodo by Aku Aspila, Markku Heinisuo, Virpi Leivo, Mikko Malaska, Kristo Mela, Sami Pajunen, Mika Vuorela

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Reliability parameters calculation of restorable objects with regard to inaccuracies in the initial data by L. I. Kulbak, T. S. Martinovich

“…The method of reliability parameters calculation of objects with regard to inaccuracies of source data is provided. In this case, only restorable objects are considered, the reliability of which is ensured by structural redundancy with limited multiplicity. …”
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Examining the physical structure of hospitals of Kashan university of Medical Sciences based on elderly-friendly criteria and the elderly\'s satisfaction by Fatemeh Sadat Izadi-Avanji, Azam Fotovati, Mohsen Taghadosi, Amene Taghdisi

“…The study aimed to examining the physical structure of hospitals affiliated to Kashan university of Medical Sciences based on elderly-friendly hospitals and the elderly's satisfaction. …”
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Analysis of strengths, weaknesses, opportunities, and threats: Analytical hierarchy process based dental waste management in Odisha by Somalee Mahapatra, Manoranjan Dash, Subhashis Mohanty

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Effects of Air-side Structure on Heat Transfer and Flow Performance of Multiple Micro-channel Parallel Flow Condenser by Gu Bo, Fang Jihua, Zhao Pengcheng

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COMPLEXES OF LEAD (II)*: CRYSTAL STRUCTURES OF L2Pb (NO,), AND L2Pb(SCN), L=Z(AMINOMETHYL) PYRIDINE

“…The reactions of Pb(N0 ) and Pb(SCN)2 with 2-(aminomethy1)pyridine (C H N = L) yielded colourless crystals of L Pb(N0 ) ( I ) and L Pb(SCN) , (2), respectively. Their structures were determined by X-ray crystallography. …”
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Development of deep-underground engineering structures via 2D and 3D RQD prediction using non-invasive CSAMT by Muhammad Hasan, Lijun Su, Peng Cui, Yanjun Shang

“…The results are significant because they help us make sense of complicated geological situations, estimate the likelihood of early collapse, and build deep underground structures safely, steadily, and affordably. Our approach leads to more objective indices, helps in the development of more accurate geotechnical structures, and reduces inconsistencies between appropriate geomechanical models and sparse data.…”
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