Tirzepatide, a dual GIP/GLP1-receptor co-agonist preserves cardiac function and improves survival in angiotensin II-induced heart failure model in mice: comparison to liraglutide by Zsombor I. Hegedűs, Márk E. Jakab, Tamás G. Gergely, Nabil V. Sayour, Andrea Kovács, Sára Antal, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga, Viktória E. Tóth

“…Animals were treated with vehicle (Veh), Lira (300 µg/day i.p.) or TZP (48 µg/day s.c.) for 14 days in the following groups: Sham/Veh (n = 7), AngII/Veh (n = 15), Sham/Lira (n = 7), AngII/Lira (n = 15), Sham/TZP (n = 8), AngII/TZP (n = 15). Cardiac structural, functional and molecular characteristics were assessed by echocardiography, ECG, immunohistochemistry, flow cytometry and qRT-PCR. …”
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Facilitators, barriers, and strategies for the implementation of peer-led tuberculosis active case finding among people who use drugs in Dar es Salaam, Tanzania. by Lilian Tina Minja, Liana Monica Minja, Kilian Mlalama, Doreen Pamba, Jerry Hella, Samwel Likindikoki, Cassian Nyandindi, Jessie Mbwambo, Klaus Reither, Jennifer M Belus

“…Despite the high incidence and prevalence of TB among people who use drugs (PWUD), there is a significant gap in data, on their perspectives, regarding the implementation of TB ACF services. …”
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Prescription of guideline‐directed medical therapy in heart failure: impact on mortality and readmission by Martin Möckel, Samipa Pudasaini, Kristina Feldmann, Henning Thomas Baberg, Benny Levenson, Jürgen Malzahn, Thomas Mansky, Guido Michels, Christian Günster, Elke Jeschke

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Research on the Influence Mechanism of “Scenery-Relics” Landscape on Public Spatio-Temporal Behavior and Perception Preference in Industrial Wasteland: A Case Study of Shougang Ind... by Sijia QIU, Lige BAO, Jing XU, Fang WEI

“…This approach provides a theoretical reference for the design and transformation of post-industrial landscapes, the optimization of urban green space structure, and the organic renewal of industrial wastelands.…”
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Development and Psychometric Evaluation of an Instrument to Assess Physical Activity Participation Behavior Among Chinese Patients with Chronic Obstructive Pulmonary Disease by Liao Y, Wang H, Zhan Y, Liu Y, Wang W, Ke H, Lan F, Zhi Q, Li W, Yu J

“…A sample of COPD patients diagnosed over a year was randomly divided into two groups for exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to test the factor structure. The scale’s content validity, internal consistency and test-retest reliability were further assessed.Results: 433 COPD patients from four hospitals in a city in China participated in this study. …”
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Organisation of physical education in universities for students with disabilities: Modular approach by L. V. Zakharova, O. N. Moskovchenko, U. Solimene, N. V. Tretyakova, N. V. Bannikova, N. V. Lyulina, O. A. Kattsin

“…Also, the authors used the methods of mathematical statistics to process the study results. The received data were processed with Microsoft Office Excel. …”
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<i>PRKAG2</i> Syndrome: Clinical Features, Imaging Findings and Cardiac Events by Maria Sudomir, Przemysław Chmielewski, Grażyna Truszkowska, Mariusz Kłopotowski, Mateusz Śpiewak, Marta Legatowicz-Koprowska, Monika Gawor-Prokopczyk, Justyna Szczygieł, Joanna Zakrzewska-Koperska, Mariusz Kruk, Jolanta Krzysztoń-Russjan, Jacek Grzybowski, Rafał Płoski, Zofia T. Bilińska

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We know less about phosphorus retention in constructed wetlands than we think we do: A quantitative literature synthesis by Kenneth J. Anderson, Bishwodeep Adhikari, Olivia F. Schloegel, Raissa Marques Mendonca, Michael P. Back, Nicholas Brocato, Jacob A. Cianci-Gaskill, Steven E. McMurray, Christie Bahlai, David M. Costello, Lauren Kinsman-Costello

“…We found that, while differences among broad wetland structural groupings exist, measured rates of phosphorus retention are highly variable. …”
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Quality of Life after Brain Injury in children aged six and seven years (QOLIBRI-KIDDY) – development and scale analysis of the first disease-specific self-report instrument for yo... by Nicole von Steinbuechel, Marina Zeldovich, Fabian Bockhop, Ugne Krenz, Dagmar Timmermann, Anna Buchheim, Inga K. Koerte, Michaela Veronika Bonfert, Steffen Berweck, Matthias Kieslich, Knut Brockmann, Maike Roediger, Sven Greving, Axel Neu, Ulrike Wartemann, Joachim Suss, Christian Auer, Holger Muehlan, Katrin Cunitz

“…After item reduction based on a confirmatory scale analysis considering the six-factor structure of the questionnaire versions for older children, adolescents, and adults (Cognition, Self, Daily Life & Autonomy, Social Relationships, Emotions, Physical Problems), its reliability and validity were investigated. …”
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A rare haplotype of the GJD3 gene segregating in familial Meniere’s disease interferes with connexin assembly by Alba Escalera-Balsera, Paula Robles-Bolivar, Alberto M. Parra-Perez, Silvia Murillo-Cuesta, Han Chow Chua, Lourdes Rodríguez-de la Rosa, Julio Contreras, Ewa Domarecka, Juan Carlos Amor-Dorado, Andrés Soto-Varela, Isabel Varela-Nieto, Agnieszka J. Szczepek, Alvaro Gallego-Martinez, Jose A. Lopez-Escamez

“…The connexin monomer and the homomeric connexon structural models were predicted using AlphaFold2 and HDOCK. …”
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“A cure might help, but it won't erase it all”: a qualitative study of policy challenges and priorities for long‐term survivors of HIV in the United States by Ali Ahmed, Jeff Taylor, Rachel Lau, Joyce Ching‐Jung Lai, Sithara Deshan Diunugala, Michael Louella, Thomas J. Villa, William Freshwater, Dawn Averitt, Maile Karris, Jeff Berry, Lynda Dee, Karine Dubé

“…Using inductive thematic analysis, we identified key policy concerns and recommendations based on participants’ lived experiences. Data collection continued until thematic saturation was reached. …”
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Urgent natural foci infections transmitted by ticks in Saint-Petersburg by V. V. Nechaev, A. A. Yakovlev, A. N. Uskov, L. E. Boburina, N. V. Lavrova, M. N. Pogromskaya, B. I. Aslanov, A. O. Shapar, S. V. Pavlenko, L. N. Pozhidaeva, A. K. Ivanov, A. I. Kravtsova, S. A. Leppik, E. I. Vitovich, M. I. Fedunyak

“…The clinical forms of both diseases did not differ in their structure from the country data, however after 2012 subclinical forms were more common in women. …”
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Rapid escalation and release of risks to forest ecosystems triggered by warming: Insights from tree growth synchrony in temperate forests by Liangjun Zhu, Danyang Yuan, J. Julio Camarero, David J. Cooper, Mai-He Li, Shuguang Liu, Xiaochun Wang, Paolo Cherubini

“…These results provide crucial insights for forest management practice to enhance structural diversity and resilience capacity against climate change-induced synchrony shifts.…”
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Genome-wide identification and expression analysis of phytochrome gene family in Aikang58 wheat (Triticum aestivum L.) by Zhu Yang, Zhu Yang, Wenjie Kan, Wenjie Kan, Ziqi Wang, Caiguo Tang, Yuan Cheng, Yuan Cheng, Dacheng Wang, Dacheng Wang, Yameng Gao, Lifang Wu, Lifang Wu

“…In this study, we employed bioinformatics methods to identify eight TaAkPHY genes in the Aikang58 wheat variety. Based on gene structure, conserved domains, and phylogenetic relationships, the TaAkPHY gene family exhibits a high degree of conservation. …”
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The effect of sociodemographic, socioeconomic, and health factors on healthcare utilization in cardiovascular patients in Serbia: a part of National Health Survey by Tamara Lekovic, Tamara Lekovic, Nikoleta Janicijevic, Milos Potezica, Nela Djonovic, Nela Djonovic, Dragan Vasiljevic, Katarina Janicijevic, Melanija Tepavcevic, Snezana Knezevic, Jelena Vuckovic Filipovic, Jelena Vuckovic Filipovic, Amela Rastoder Celebic, Amela Rastoder Celebic, Svetlana Vukosavljevic, Svetlana Vukosavljevic, Maja Mirocevic Rotolo, Maja Mirocevic Rotolo, Dalibor Stajic

“…ObjectivesThis cross-sectional analytical study explores the predictors of the healthcare utilization in the adult population with cardiovascular diseases.MethodologyThe research was carried out as part of the fourth Serbian National Health Survey, in the period from October to December 2019, as a descriptive, cross-sectional analytical study and included the population of cardiovascular patients (N = 4,712) aged over 20 years; Descriptive and inferential statistical methods, including percentage-based structure indicators, Chi-square (χ2) tests for categorical variable differences, and prevalence ratio for examining relationships between dependent and independent variables, were used in the data analysis.ResultsThe analysis identified several significant contributors to cardiovascular healthcare utilization, emphasizing distinct and overlapping factors that impact various types of healthcare use. …”
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“Vaccinating a child is upon the woman”: implications for improving uptake for the recently introduced second dose of measles-containing vaccine based on a rapid community assessme... by Adelline Twimukye, Nessa Ryan, Flavia Vivian Najjuma, Yvette Wibabara, Judith Nanyondo, Shillah Nakato, Maria Sarah Nabaggala, Ciara Sugerman, Daniel Kadobera, Rita Atugonza, John Kamulegeya, Joseph Magoola, Racheal Beyagira, Mohammed Lamorde, Alex Riolexus Ario, Alfred Driwale, Shibani Kulkarni

“…We conducted a rapid analysis based of debriefing notes and in-depth thematic analysis of translated transcripts. Data were analyzed using NVivo version 12, wherein we used the framework analysis approach to define and structure codes deductively and inductively to identify themes. …”
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Precise aftershock activity in the marine source region of the 2024 Noto-Hanto earthquake by rapid response observation using ocean bottom seismometers by Masanao Shinohara, Ryota Hino, Tsutomu Takahashi, Koichiro Obana, Shuichi Kodaira, Ryosuke Azuma, Tomoaki Yamada, Takeshi Akuhara, Yusuke Yamashita, Eiji Kurashimo, Yoshio Murai, Takehi lsse, Kazuo Nakahigashi, Hisatoshi Baba, Yusaku Ohta, Yoshihiro Ito, Hiroshi Yakiwara, Yukihiro Nakatani, Gou Fujie, Toshinori Sato, Hajime Shiobara, Kimihiro Mochizuki, Shin’ichi Sakai, The R/V Hakuho-maru KH-24-JE01 and KH-24-JE02C shipboard science parties

“…A velocity model was derived from the velocity structure by the marine seismic survey. Focal mechanisms were estimated using the grid search method based on the polarities of the first Pwave arrivals. …”
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How national leaders keep ‘us’ safe: A longitudinal, four-nation study exploring the role of identity leadership as a predictor of adherence to COVID-19 non-pharmaceutical interven... by Niklas K Steffens, S Alexander Haslam, Svenja B Frenzel, Nina M Junker, Aidos Bolatov, Valerie A Erkens, Jan A Häusser, Ronit Kark, Ines Meyer, Andreas Mojzisch, Lucas Monzani, Stephen D Reicher, Adil Samekin, Sebastian C Schuh, Liliya Sultanova, Dina Van Dijk, Llewellyn E van Zyl, Rolf van Dick

“…Hypotheses testing was conducted with structural equation modelling.Setting Data collection during the COVID-19 pandemic in China, Germany, Israel and the USA in April/May 2020 and four weeks later.Participants Adults in China (n=548, 66.6% women), Germany (n=182, 78% women), Israel (n=198, 51.0% women) and the USA (n=108, 58.3% women).Measures Identity leadership (assessed by the four-item Identity Leadership Inventory Short-Form) at Time 1, perceived shared national identification (PSNI; assessed with four items) and adherence to health-protective NPIs (assessed with 10 items that describe different health-protective interventions; for example, wearing face masks) at Time 2.Results Identity leadership was positively associated with PSNI (95% CI 0.11 to 0.30, p&lt;0.001) in all countries. …”
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The study for asthma in older adults: a combined analysis of the effects of occupational asthmagens, high body-mass index and smoking by Jia-Qi Wang, Jia-Qi Wang, Yuan-Yu Liang, Yuan-Yu Liang, Zhong-Xue Zhao, Zhong-Xue Zhao, Wei Xie, Wan-Ning Sun, Wan-Ning Sun, Ji-Yu Zou, Ji-Yu Zou, Xiao-Dong Lv, Xiao-Dong Lv, Youfu He, Li-Jian Pang, Li-Jian Pang

“…Gender-stratified analysis showed that the risk burden of smoking was higher in older men in Asia, whereas the high BMI-related burden was higher in women in more developed regions.ConclusionThis study demonstrates a structural shift in the composition of asthma risk factors among older adults, with high BMI emerging as a dominant contributor amid declining traditional behavioral risks such as smoking. …”
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First-principles study of beryllium thermodynamics and clustering mechanism in molybdenum: Effects of vacancies and self-interstitial atoms by Aoyu Mo, Haijun Li, Fuquan Guo, Xiaowei Ma, Yunshan Xiong, Peng Shao, Bo Li, Kun Jie Yang, Yue-Lin Liu, Quan-Fu Han

“…When the number of Be atoms reaches six, they form an approximately “octahedral” structure, displacing a central Mo atom and generating a Be6V cluster and an SIA. …”
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