Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains by Yue Xiang, Saixian Zhang, Yi Huang, Zhuqing Zheng, Jiahui Sun, Qiulin Zhao, Peng Zhou, Xiaolong Qi, Jingjin Li, Fuyang Xiong, Jing Xu, Shengquan Wang, Liangliang Fu, Xinyun Li

“…Abstract Background Pig brains serve as a valuable biomedical model for studying brain-related diseases due to their significant structural similarities to the human brain. Furthermore, the long-term domestication and artificial selection of domestic pigs have profoundly shaped their brains, making them an interesting subject for research. …”
Get full text

Advancing molecular diagnostics of myotonic dystrophy type 1 using short-read whole genome sequencing by Ingrid Lojova, Marcel Kucharik, Zuzana Pös, Andrej Balaz, Andrea Zatkova, Eva Tothova Tarova, Jaroslav Budis, Ludevit Kadasi, Tomas Szemes, Jan Radvanszky

“…WGS was found to be superior in elucidating the sequence structure of the motifs, even if they fall outside the sizing limit (from partial reads). …”
Get full text

Flares on TRAPPIST-1 Reveal the Spectrum of Magnetic Features on Its Surface by Valeriy Vasilyev, Nadiia Kostogryz, Alexander I. Shapiro, Astrid M. Veronig, Benjamin V. Rackham, Christoph Schirninger, Julien de Wit, Ward Howard, Jeff Valenti, Adina D. Feinstein, Olivia Lim, Sara Seager, Laurent Gizon, Sami K. Solanki

“…Our analysis rules out lingering flare decay as the cause of the flux enhancement and thus, points to structural changes on the stellar surface induced by flares. …”
Get full text

Can social adversity and mental, physical and oral multimorbidity form a syndemic? A concept and protocol paper by Easter Joury, Easter Joury, Eliana Nakhleh, Ed Beveridge, Derek Tracy, Derek Tracy, Derek Tracy, Derek Tracy, Ellie Heidari, Ellie Heidari, David Shiers, David Shiers, David Shiers, Silke Vereeken, Emily Peckham, Simon Gilbody, Simon Gilbody, Jayati Das-Munshi, Farida Fortune, Farida Fortune, Vishal R. Aggarwal, Masuma Mishu, Masuma Mishu, Joseph Firth, Joseph Firth, Kamaldeep Bhui, Kamaldeep Bhui, Kamaldeep Bhui, Kamaldeep Bhui

“…Structural equation modelling (SEM) will be utilised to conceptualise syndemic factors and model complex relationships between directly observed and indirectly observed (latent) variables (syndemic constructs).Discussionthe syndemic conceptualisation provides a valuable framework to understand health and illness, and hence to better design and deliver effective and cost-effective preventative and curative integrated (syndemic) care to improve patient and population health. …”
Get full text

Chronic exposure to polyethylene terephthalate microplastics induces gut microbiota dysbiosis and disordered hepatic lipid metabolism in mice by Tao Lu, Huan Liu, Xiaoqing Yuan, Desheng Li, Guanqing Zhang, Yue Wang, Qiqiang Xie, Xinhao Wang, Jingjian Chi, Zhenzhen Wang, Shaoping Wang, Yanling Gao, Ling Zhou, Maolei Xu

“…The results confirmed, for the first time, that PET MPs can induce oxidative stress, lipid accumulation, and apoptosis in liver cells, resulting in structural damage and functional abnormalities in the liver. …”
Get full text

Piloting the options assessment toolkit with national malaria programme leaders from the Asia–Pacific countries: a meeting report by Manash Shrestha, Sanjaya Acharya, Josselyn Neukom, Karma Lhazeen, Ngo Duc Thang, Muhammad Naeem Habib, Lyndes Wini, Tobgyel Tobgyel, Kesang Wangchuk, Huy Rekol, Lek Dysoley, Siv Sovannaroth, Minerva Simatuopang, Helen Dewi Prameswari, Asik Surya, Zau Ring, Mohammad Qasim Khan, Boualam Khamlome, Mohd Hafizi Abdul Hamid, Ram Kumar Mahato, Top Thapa, Sheen Angelou Juangco, Hee Il Lee, Hyun Il Shin, Kumudu Gunasekera, Champa Aluthwera, Prayuth Sudathip, Rungrawee Timpontree, Hoang Dinh Canh, Sonia Cheung, Muhammad Zeeshan Haroon, Shreehari Acharya, Robert J. Commons, Bipin Adhikari, Varunika Ruwanpura, Phone Si Hein, Abhijit Sharma, Poe Poe Aung, Neena Valecha, Kamala Thriemer, Caroline A. Lynch

“…Thematic analysis of qualitative data revealed that NMPs found the OAT useful and timely for structuring malaria policy discussions. …”
Get full text

Tungsten solubility and speciation in hydrothermal solutions revealed by in situ X-ray absorption spectroscopy by M. Borchert, M. Borchert, M. A. Kokh, M. A. Kokh, M. Louvel, M. Louvel, E. F. Bazarkina, E. F. Bazarkina, A. Loges, E. Welter, D. Testemale, R. Al Abed, S. Klemme, M. Wilke

“…X-ray spectroscopic data measured in situ – with X-ray absorption near-edge structure (XANES) and extended X-ray absorption fine structure (EXAFS) – were applied to characterize the symmetry and the type of atoms of the first coordination shell of W aqueous complexes present in the fluid at given temperatures and pressures. …”
Get full text

The haplotype-resolved telomere-to-telomere genome and OMICS analyses reveal genetic responses to tapping in rubber tree by Chaochao Li, Yuan Yuan, Zhiyi Nie, Tingkai Wu, Zhiyuan Wang, Jiangxia Qiao, Zhi Deng, Xiaobo Wang, Dong Xu, Xu Wang, Shuo Cao, Bingqin Li, Zewei An, Wenguan Wu, Zhongxin Jin, Huasun Huang, Wei Hu, Yongfeng Zhou, Han Cheng

“…We present the haplotype-resolved, telomere-to-telomere, gap-free genome assembly of the cultivar CATAS 7-33–97, with both haplotypes containing complete telomeric and centromeric regions. Structural variations, including a 32.71 Mb inversion on chromosome 8, are identified. …”
Get full text

Standardization of epistemic trust/mistrust/credulity questionnaire: Examining validity and reliability among adolescents Standardization of ETMCQ among adolescents by Raziyeh Hashemi, Mehdi Reza Sarafraz, Habib Hadian Fard, Mohammad Reza Taghavi

“…Examining the three-factor structure of the Epistemic Trust Questionnaire, confirmatory factor analysis was performed, with results shown in the table below.The value of X2/df and RMSEA indices are 86.2 and 0.078 respectively. …”
Get full text

Examining the effect of knowledge-based leadership on organizational innovation with the mediating role of illusion of control and rationality by davar Dirmina, Gholamhasan Shirdel, Seyyed Javad Iranban

“…The statistical method used in this study was the structural modeling method based on the partial least squares approach and Smart PLS3 software. …”
Get full text

Index System and Evaluation Method of Geological Environment Suitability for Human Health by Xingchun JIAO, Zhaohe ZHANG, Wei FANG, Ruimin LI, Jiuchen LIU, Wenbin JIA

“…Geological background characteristics, including tectonic structure, lithologic features, and landform configuration shape the living conditions of human being. …”
Get full text

Components of stakeholder participation to create value in the banking industry in East Azerbaijan Agricultural Bank by Alireza Tagavi, Alireza Bafandeh Zendeh, Samad Aali

“…This research is developmental in terms of the goal, descriptive-exploratory in terms of the type of method, qualitative in terms of the method of collecting data, and meta-synthesis approach in terms of the method of conducting the research. …”
Get full text

The relationship between a numbers of administrative instructions in implementation the process of reducing employees by Agreen Abdoulla Azeez, Tarik Atan

“…Coronbach. (1951) Coefficient of Alpha and Internal Structure of Test, Psychometrika, 16(3) Manfred, F. …”
Get full text

Expression characteristics and functional identification of PpD2 gene in peach (Prunus persica) by XIE Hefang, ZHANG Yajia, ZHANG Junjie, LIAN Xiaodong, ZHANG Haipeng, CHENG Jun, WANG Wei, HOU Nan, WANG Lei, ZHENG Xianbo, FENG Jiancan, WANG Xiaobei, TAN Bin

“…In this context, pillar peach germplasm, which exhibits smaller branch angles and fewer secondary branches, offers a promising alternative for improving tree structure. Optimizing tree architecture can enhance light interception, reduce labor inputs, and improve fruit quality, thereby contributing to sustainable peach production. …”
Get full text

Genome-wide identification and expression of the HB gene family during overwintering in Korla pear (Pyrus sinkiangensis) by LIU Xiaoyan, WANG Lijuan, YANG Shenghui, LUO Guanghong, ZHU Jianbo

“…Comprehensive analyses were performed, including phylogenetic relationships, chromosomal localization, gene structure, promoter cis-acting elements and family-wide collinearity. …”
Get full text

Adherence to Life’s Essential 8 enhances gut microbiota diversity and cognitive performance by Yannick N. Wadop, Jazmyn Muhammad, Rebecca Bernal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Claudia L. Satizabal, Alexa Beiser, Alexa Beiser, Alexa Beiser, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramachandran S. Vasan, Ramnik Xavier, Ramnik Xavier, Ramnik Xavier, Tiffany Kautz, Tiffany Kautz, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Sudha Seshadri, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Jayandra Jung Himali, Bernard Fongang, Bernard Fongang, Bernard Fongang

Get full text

The glaciers of the Dolomites: the last 40 years of melting by A. Securo, A. Securo, A. Securo, C. Del Gobbo, G. Baccolo, G. Baccolo, C. Barbante, C. Barbante, C. Barbante, M. Citterio, M. Citterio, F. De Blasi, F. De Blasi, F. De Blasi, M. Marcer, M. Marcer, M. Valt, R. R. Colucci, R. R. Colucci, R. R. Colucci

“…Calculations are based on geodetic data: high resolution and accuracy are obtained with uncrewed aerial vehicle (UAV), structure from motion (SfM), and airborne light detection and ranging (lidar) methods, from 2010 to 2023. …”
Get full text

Design and rationale of MYOFLAME-19 randomised controlled trial: MYOcardial protection to reduce post-COVID inFLAMmatory heart disease using cardiovascular magnetic resonance Endpo... by Valentina O. Puntmann, Dietrich Beitzke, Andreas Kammerlander, Inga Voges, Dominik D. Gabbert, Marcus Doerr, Bishwas Chamling, Biykem Bozkurt, Juan Carlos Kaski, Erica Spatz, Eva Herrmann, Gernot Rohde, Philipp DeLeuw, Lenka Taylor, Christine Windemuth-Kieselbach, Cornelia Harz, Marta Santiuste, Laura Schoeckel, Juliana Hirayama, Peter C. Taylor, Colin Berry, Eike Nagel

“…ABSTRACT: Background: Cardiac symptoms due to postacute inflammatory cardiac involvement affect a broad segment of previously well people with only mild acute coronavirus disease 2019 (COVID-19) illness and without overt structural heart disease. Cardiovascular magnetic resonance (CMR) imaging can identify the underlying subclinical disease process, which is associated with chronic cardiac symptoms. …”
Get full text

Percepções de atletas paralímpicos sobre a inclusão social por meio do esporte (Paralympic athletes perceptions about social inclusion through sport) by Bruna Solera, Patrick Paludett Flores, Ana Luiza Barbosa Anversa, Yedda Maria da Silva Caraçato, Vânia de Fátima Matias de Souza, Carlos Herold Junior

“…As a research instrument, opted for the unstructured interview, with the data collected and analyzed based on the assumptions of the content analysis and organized with the aid of the N Vivo software. …”
Get full text

Integrated assessment of antimicrobial stewardship in carbapenem resistant Klebsiella pneumoniae prevalent hospitals in China: a multidisciplinary surveillance network-based survey by Haishaerjiang Wushouer, Weibin Li, Junxuan Yu, Lin Hu, Xiaodong Guan, Xiaolin Liu, Anhua Wu, Xiaoqiang Yang, Minggui Wang, Yingchun Xu, Yanping Luo, Xun Huang, Luwen Shi

“…Five key areas were identified for improving multidisciplinary AMS: organizational structure, staffing and training, drug formulary and prescription management, laboratory testing and quality control, and clinical sampling and data reporting. …”
Get full text