Benzbromarone Analog SAR: Potent hURAT1 (SLC22A12) Inhibitors and Drug Transporter Interaction Studies by Jutabha P, Kumar V, Anzai N, Rice PJ, Lightner JW, Endou H, Wempe MF

“…One, to report two benzbromarone analogs and test their in vitro activity in the URAT1 inhibition assay; and two, to probe the structure–activity relationship (SAR) of various benzbromarone analogs regarding other drug transporters that may play a role in the uric acid uptake/elimination interplay.Methods: In brief, chemical synthesis of two benzbromarone analogs was prepared using methods analogous to those reported. …”
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A család ereje: A házasságban élés és a nagycsaládos lét kapcsolata a jóllét különböző mutatóival by Andrea FERENCZI, Zsuzsanna KÖVI, Veronika MÉSZÁROS

“… The Strength of the Family: Links between Marital Status, Large Family Structure, and Indicators of Well-Being. THEORETICAL BACKGROUND – Based on previous empirical findings, the relationship between family formation, the number of children, and subjective well-being cannot be considered unambiguous. …”
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Negotiating Islamic Law through Custom: Resistance in Family Law Practices among the Anak Dalam Community in Jambi by Illy Yanti, Yuliatin Yuliatin, Siti Mahmudah, Mahluddin Mahluddin, Yuniar Galuh Larasati

“…Dengan pendekatan sosio-legal dan metode kualitatif, penelitian ini mengumpulkan data melalui wawancara mendalam dengan tujuh informan kunci: tokoh agama, tumenggung (kepala suku), pemimpin adat, pendamping komunitas, pejabat lokal, dan anggota komunitas SAD. …”
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Explanation of Good Governance Factors in Shiraz by Ehsan Heidarzadeh, Mojtaba Arasteh, Elnaz Rafiee

“…In the following, the data obtained from the questionnaires have been entered into the SPSS software. …”
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The mediating role of self-compassion in the relationship between childhood trauma and the symptoms of body dysmorphic disorder by Motahhareh Kargar Shooroki, Azadeh Choobforoushzadeh, Azra Mohammadpanah Ardakan

“…Methods A cross-sectional design employing structural equation modeling (SEM) was utilized to construct an optimal model for BDD symptoms, where the mediating role of self-compassion was tested in the relationship between childhood trauma and BDD symptoms. …”
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Skeletal Muscle‐Specific Deletion of E3 Ligase Asb2 Enhances Muscle Mass and Strength by Hye Rim Jang, Shi‐Young Park, Yeonmi Lee, Dongjin Lee, Jongjun Lee, Yoonil Cho, Cheol Soo Choi, Hui‐Young Lee

“…Notably, desmin, a protein critical for structural integrity and mitochondrial function, was identified as a target protein of the ASB2 E3 ligase. …”
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Postpartum maternal bonding scale: Development and validation in a low- and middle- income country setting. by Bushra Khan, Seyi Soremekun, Waqas Hameed, Bilal Iqbal Avan

“…After multiple rounds of expert review and cognitive pretesting, a 30-item tool was selected for field testing. Using data from 310 postpartum women, we examined the tool's structure through exploratory (EFA) and confirmatory factor analysis (CFA), leading to a refined 12-item tool. …”
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CATHODOLUMINESCENCE AND RAMAN SPECTROSCOPY AS A BASIS FOR THE SELECTION OF REFERENCE SAMPLES FOR LA-ICP-MS ANALYSIS OF ZIRCON by S. L. Votyakov, M. V. Chervyakovskaya, Yu. V. Shchapova, E. A. Pankrushina, G. B. Mikhalevsky, V. S. Chervyakovsky

“…The Аi–Вi–Сi diagram is compared with similar data on the cathodoluminescence of the reference samples.…”
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Study on the Impact of Exclosures on the Physicochemical Properties of Rangeland Soil (Case Study: Northern Golestan Province, Sufikam Rangelands) by Rasool Khatibi, Mohsen Farahi

“…Among the remedial methods for degraded soils, increasing rangeland fertility and striving to improve soil structure stability, reducing livestock trampling through grazing restrictions, are highlighted. …”
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Improvement and Validation of System Code for Thermal-hydraulic Analysis of In-pool Passive Residual Heat Removal System by LIAN Qiang1, 2, 3, ZHU Longxiang1, 2, 3, TANG Simiao1, 2, 3, HUANG Tao4, ZHANG Yong4, PAN Liangming1, 2

“…This study can provide the basic technology support for the structure design of PRHRS and safety analysis of the reactor system. …”
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Interrelations of physical state parameters and biological age of students in the process of physical education by Oleksandr Pryimakov, Marek Sawczuk, Stanislav Prysiazhniuk, Nataliya Mazurok, Oleksandr Petrachkov

“…It was found that the key indicators of students' physical state (PS) structure, which exerted the most significant influence on BMI, differ between young men and women. …”
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Psychological adaptation and quality of life of patients who underwent lower limb amputation due to cancer by O Yu Shchelkova, M V Iakovleva, E B Usmanova, E A Sushentsov, D I Sofronov

“…It was found that functional capability (p<0.01), objective (p<0.001) and subjective (p<0.001) severity of pain syndrome, as well as employment (p=0.05) have the lowest indicators in group 1 compared with group 2; at the same time, the levels of QoL in both groups of patients do not differ and do not correspond the expert assessment, exceeding it; patients rate their cognitive and emotional activity most highly; the lowest, physical and role activity, and financial impact. In the structure of coping of group 1, the strategy “Seeking for social support” predominates; the values of the scales “Distancing” (p=0.05), “Escape–avoidance” (0.1<p<0.05), “Positive reappraisal” (p<0.05) are higher than in group 2, but lower than average normative values. …”
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The Effect of Selective and Mass Immunization Against Pneumococcal Infection on the Morbidity and Mortality due to Community-Acquired Pneumonia in Children Under 5 Years of Age by Vadislav V. Semerikov, Elena S. Zubova, Lyudmila V. Sofronova

“…It is also important to estimate the rate of hospital admissions in this patient group, long-term and annual cycles, morbidity age and etiology structure, and mortality due to community-acquired pneumonia as one of the most common form of pneumococcal disease. …”
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Increased Brain Iron Deposition in the Putamen in Patients with Type 2 Diabetes Mellitus Detected by Quantitative Susceptibility Mapping by Jing Li, Qihao Zhang, Nan Zhang, Lingfei Guo

“…The underlying brain structural changes in type 2 diabetes mellitus (T2DM) patients have attracted increasing attention. …”
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Changes in physical activity and sedentary behaviours of children living in Italy due to the COVID-19 pandemic: the EPaS-ISS study by Paola Nardone, Serena Broccoli, Angela Spinelli, Marta Buoncristiano, Silvia Andreozzi, Mauro Bucciarelli, Marco Giustini, Silvia Ciardullo, on behalf of the EPaS-ISS Group

“…The possible effects of gender, geographical area of residence, parents’ nationality and educational level, family structure, family-perceived wealth, availability of home outdoor spaces and house size were investigated. …”
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Urban Hierarchy Migration Model and Impact Mechanism of Graduates Admitted to the Guangdong Provincial Civil Service Examination by Wu Jinghao, Liu Ye, Tang Honglin

“…As China enters a critical transition period towards a knowledge-based economy, the optimization of the educational attainment structure and spatial distribution of the civil service, a crucial component of modernizing the national governance system and capacity, exerts a profound influence on enhancing government efficiency and fostering social progress. …”
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Coverage of HPV Vaccination and Influencing Factors Among Female College Students in Northern China by Li Yang, Chen Xing, Xue Yu, Yanrui Xu, Weibing Wang, Caiyun Chang, Qingbin Lu

“…Notably, increased knowledge was associated with vaccine hesitancy in the WTG group (<i>OR</i> = 0.45, <i>p</i> < 0.001), indicating that information overload may adversely affect decision-making processes. Structural barriers, such as cost (42.63%), safety concerns (46.59%), and misconceptions (e.g., 57.76% cited “no sexual activity” as a reason for refusal), significantly impeded vaccine uptake. …”
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Geographic variations and determinants of ever-tested for HIV among women aged 15–49 in Sierra Leone: a spatial and multi-level analysis by Lovel Fornah, Mulugeta Shegaze Shimbre, Augustus Osborne, Alieu Tommy, Agumas Fentahun Ayalew, Wei Ma

“…Method The study utilized data from the 2008, 2013, and 2019 Sierra Leone Demographic Health Surveys, comprising 39,606 women aged 15–49. …”
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Application of Statistical Methods for the Characterization of Radon Distribution in Indoor Environments: A Case Study in Lima, Peru by Rafael Liza, Félix Díaz, Patrizia Pereyra, Daniel Palacios, Nhell Cerna, Luis Curo, Max Riva

“…Additionally, analysis of variance (ANOVA) was used to evaluate the influence of environmental and structural factors on radon variability. Non-normally distributed data were normalized using a Box–Cox transformation to improve statistical assumptions, enabling subsequent geostatistical analyses. …”
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Hippocampus alterations in post-traumatic stress disorder among survivors of the consecutive Kahramanmaraş (Turkey) earthquakes in February 6, 2023: earthquake brain at the end of... by Olga Bayar-Kapıcı, Yaşar Kapıcı, Dilek Örüm, Mehmet Hamdi Örüm, Mehmet Şirik

“…Sociodemographic and clinical data were obtained through the patient registration system. …”
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