Cell-derived exosome therapy for diabetic peripheral neuropathy: a preclinical animal studies systematic review and meta-analysis by Xianying Lu, Ran Xu, Xiaohui Dong, Dingxi Bai, Wenting Ji, Xinyu Chen, Huan Chen, Chaoming Hou, Jing Gao

“…The outcome indicators consisted of at least one of the three key DPN endpoints (electrophysiology, behavioural assessment, and nerve structure) based on the Neurodiab guidelines. R 4.4.2 software was used to conduct all statistical analyses. …”
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The pattern of state organization in the new constitution of Lithuania: A third way between the presidential and parliamentary systems? by Andreas Hollstein

“…If not—how could such a structure be classified? The author compares the data he has arranged in the second part with the premises of theoretical patterns. …”
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Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway by Ju Huang, Ju Huang, Jing Li, Jing Li, Zhijun Geng, Zhijun Geng, Lixia Yin, Lixia Yin, Minzhu Niu, Qingqing Li, Qingqing Li, Xinyue Liu, Xinke Cheng, Xiaofeng Zhang, Xue Song, Xue Song, Yueyue Wang, Yueyue Wang, Lian Wang, Lugen Zuo, Jianguo Hu, Jianguo Hu

“…Background and aimsPatients with Crohn’s disease (CD) exhibit excessive apoptosis of intestinal epithelial cells (IECs), which contributes to damage to the intestinal barrier structure and function, thereby playing a role in the progression of colitis. …”
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Population-based cross-sectional seroprevalence study of SARS-CoV-2 infection in urban residential areas in Ghana by John H Amuasi, Aurélia Souares, Eva Lorenz, Wibke Loag, Anthony Afum-Adjei Awuah, Sylvester Newton, Christian Obirikorang, Evans Asamoah Adu, Eric Ebenezer Amprofi Boham, Alexander Owusu Boakye, Hakim Alani, Nana Safi Almoustapha, James Deke, Welbeck Odame Dzadey, Louis Adu-Amoah, Sally-Ann Kroduah, Mary Ama Grant, Gracelyn Asare, Amos Amoako-Adusei, Jenny Kettenbeil, Yaw Adu Sarkodie, Ebenezer Oduro, Alfred E Yawson, Stephen Apanga, Rose Odotei Adjei, Austin Gideon Adobasom Anane, Oumou Maiga Ascofare, May Jurgen, Nicole S Struck

“…Bayesian models with poststratification weighting of the demographic structure of the sample population were used for seroprevalence estimates, accounting for the uncertainty of diagnostic assay in a hierarchical model. …”
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Etiological mechanisms underlying the hazard factors and inflammatory bowel disease: a prospective cohort study by Yi Tao, Yongjia Li, Tianyi Zhou, Lei Zhao, Pan Li, Minghong Sun, Lijuan Zhang, Lihong Yang, Ting Chen, Xuemei Lian, Xiaoni Zhong

“…Finally, we constructed a structural equation model to elucidate the complex pathogenic mechanisms and interactions among genetic risks, lifestyle factors, dietary habits, comorbidities, and immune metabolism in the progression of IBD. …”
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Evaluation of control strategies for airport refueling system by Qing SHEN, Peng LIU, Jing GONG, Xiaoping LI, Yanqing WANG

“…Subsequently, within the setting of an airport in China, encompassing its actual pipeline network structure and refueling data, simulations were conducted, incorporating different control modes (single-pump frequency conversion and multi-pump frequency conversion) and diverse measurement parameters (pressurefrequency and pressure-flow). …”
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Manipulation in root-associated microbiome via carbon nanosol for plant growth improvements by Lingtong Cheng, Jiemeng Tao, Peng Lu, Taibo Liang, Xutao Li, Dong Chang, Huan Su, Wei He, Zechao Qu, He Li, Wenjun Mu, Wei Zhang, Nan Liu, Jianfeng Zhang, Peijian Cao, Jingjing Jin

“…Fungal and bacterial communities had different response patterns for CNS treatment, with phased and dose-dependent effects, with the most significant changes in microbial community structure observed at 1200 mg/L after 10 days of treatment. …”
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Facial Expression Recognition and Digital Images Infosecurity for Prevention Care System Application in Sudden Infant Death Syndrome Monitoring by Chih-Te Tsai, Chia-Hung Lin, Hsiang-Yueh Lai, Yu-En Cheng, Ping-Tzan Huang, Neng-Sheng Pai, Chien-Ming Li

“…For image infosecurity testing, the number of pixel changing rate (NPCR), unified averaged changed intensity (UACI), and structural similarity index measurement (SSIM) were employed to evaluate the performances for encryption and decryption processes, ensuring confidentiality, recoverability, and availability of transmitted images. …”
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For-profit growth and academic decline: a retrospective nationwide assessment of Brazilian medical schools by Bruno B. Andrade, Bruno B. Andrade, Klauss Villalva-Serra, Klauss Villalva-Serra, Rodrigo C. Menezes, Rodrigo C. Menezes, Luiz F. Quintanilha, Katia de Miranda Avena, Katia de Miranda Avena

“…These patterns suggest a structural misalignment between the commercial logic of expansion and the core educational mission of medical training. …”
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The Improvement Effects of Intercropping Systems on Saline-Alkali Soils and Their Impact on Microbial Communities by Yan-Jun Wang, Gao-Xiang Qi, Na-Na Wang, Hong-Yun Dong, Yan Zhang, Han Lu, Ying Li, Hong-Cheng Wang, Xin-Hua Li, Hong-Yuan Liu

“…The results of this study provide data support for improving saline-alkali land through planting systems.…”
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Mitochondrial genome assembly and comparative analysis of decaploid Camellia hainanica by Shihui Zhang, Yuyan Zhang, Sheng Luo, Jie Gao, Haiyan Hu, Jinping Liu, Wenqiang Wu, Jian Wang, Xiaolong Huang, Hanggui Lai, Hanggui Lai, Dongyi Huang

“…Therefore, assembling and annotating the mitochondrial genome function of decaploid C. hainanica is of great significance.MethodsThis study successfully assembled the mitochondrial genome of decaploid C. hainanica and comprehensively annotated its functional genes using the Nanopore sequencing platform.ResultsResults showed that the mitochondrial genome is 902,617 bp in length, with a typical circular structure and a guanine–cytosine content of 45.79%. …”
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β-diversity of the herbaceous layer plant communities in natural forests and its influencing factors in Henan Province by MENG Wei1,2, DU Xiaojun2,3*, JIAO Zhihua4, GAO Xianming2, LIU Longchang1*, WANG Yu1

“…Conducting research on β-diversity(beta diversity)and its components, which reflect spatial or temporal variations in species composition among communities, helps to improve the understanding and knowledge of community structure and its maintenance mechanisms. The herbaceous layer of forest is an important part of forest community and forest ecosystem. …”
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Exploration of the relationship between partial pressure of brain tissue oxygen and intracranial pressure by Martin Shaw, Laura Moss, Ian Piper, Maya Kommer, Richard Boulton, Roddy O'Kane, Christopher Hawthorne

“…Material and methods: Patients with PbtO2 monitoring were identified from the BrainIT database, a multi-centre dataset, containing minute by minute PbtO2 and ICP readings. Missing data was imputed and a multi-level log-normal regression model with a compound symmetry correlation structure was built. …”
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COZMIC. I. Cosmological Zoom-in Simulations with Initial Conditions Beyond Cold Dark Matter by Ethan O. Nadler, Rui An, Vera Gluscevic, Andrew Benson, Xiaolong Du

“…Thus, future development of IDM SHMF models can improve IDM cross section bounds by up to a factor of ∼20 with current data. COZMIC presents an important step toward accurate small-scale structure modeling in beyond-CDM cosmologies, critical to upcoming observational searches for dark matter physics.…”
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EFFECTS OF PROLINE-RICH PEPTIDES OF THE INNATE IMMUNE SYSTEM ON DRUG-RESISTANT BACTERIAL STRAINS by M. S. Zharkova, P. M. Kopeykin, G. E. Afinogenov, D. S. Orlov, A. Yu. Artamonov, K. E. Safiullina, M. S. Sukhareva, E. V. Tsvetkova, B. L. Milman, A. G. Afinogenova, O. V. Shamova

“…Lack of hemolytic activity towards human red blood cells is an important benefit of the studied peptides when used at concentrations several times higher than those showing antimicrobial effects. The data obtained presume certain prospects for further investigations of proline-rich peptides, as well as their structural modifications, for the development of new combined drugs based on these compounds, in order to combat antibiotic-resistant microorganisms, e.g., medications for local applications, various components of medical devices, in particular, venous catheters, stents and wound dressings.…”
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The Middle to Late Triassic of Central Saudi Arabia with emphasis on the Jilh Formation. Part I: lithostratigraphy, facies and paleoenvironments, palaeontology and biostratigraphic... by Le Nindre, Yves-Michel, Vaslet, Denis, Vrielynck, Bruno, Krystyn, Leopold, Manivit, Jacques, Memesh, Abdullah, Davies, Roger Brett

“…Part II “Sequence stratigraphy, depositional and structural evolution, and regional correlations” exploits the results of Part I, providing a dynamic reconstruction and a renewed vision of the Middle to Late Triassic at the regional scale.The Jilh Formation at outcrop consists of a multilayer system of thinly bedded, mixed siliciclastics with subordinate carbonates and evaporites, representing non-marine to offshore settings. …”
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Helping people with psychosis with a low-cost intervention DIALOG+: protocol for the economic evaluation in a randomised control trial in India and Pakistan by Victoria Jane Bird, Sara Evans-Lacko, Lakshmi Venkatraman, Padmavati Ramachandran, Ashar Muhammad Malik, Renata Peppl, Sana Zehra Zehra Sajun, Onaiza Qureshi, Krishna Priya, Hufsa Sarwar

“…Incremental cost, incremental effectiveness and incremental cost-effectiveness ratios will be calculated using linear regression models with a hierarchical data structure. A probabilistic sensitivity analysis will be carried out to test for the uncertainty surrounding the estimates of cost-effectiveness.Discussion This study will provide evidence of a patient-centred approach to improve the quality of community-based care for people with psychosis in India and Pakistan. …”
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Amniotic fluid-derived stem cells: potential factories of natural and mimetic strategies for congenital malformations by Cristiane S. R. Fonteles, Julia Enterria-Rosales, Ying Lin, John W. Steele, Ramiro A. Villarreal-Leal, Jing Xiao, Daniel I. Idowu, Beck Burgelin, Bogdan J. Wlodarczyk, Richard H. Finnell, Bruna Corradetti

“…A physicochemical, structural, and molecular comparison was conducted with exosomes (EXOs) released from the same batch of cells. …”
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Metabolomic and Transcriptomic Analysis Revealed the Maturation Mechanism of White-Fleshed Strawberry by Linlin Xu, Xiaodong Chen, Qinglian Wang, Mizhen Zhao, Yushan Qiao, Zhaobiao Xie, Chuanwen Sun, Miao Sun, Weijian Cai

“…Further analysis revealed a co-expression of MYBs, bHLHs, NACs, and WRKYs with the structural genes mentioned. Overall, our findings uncovered a molecular mechanism regulating the maturation of white-fleshed strawberry, providing valuable insights for enhancing the flavor of white-fleshed strawberry through the gene-editing technique.…”
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Effects and mechanisms of supramaximal high-intensity interval training on extrapulmonary manifestations in people with and without chronic obstructive pulmonary disease (COPD-HIIT... by Johan Jakobsson, Chris Burtin, Mattias Hedlund, Carl-Johan Boraxbekk, Jonas Westman, Nina Karalija, Per Stål, Thomas Sandström, David Ruttens, Harry R. Gosker, Jana De Brandt, André Nyberg

“…Key secondary outcomes include change from baseline exercise tolerance, brain structure, and function measured by MRI, neuroinflammation measured by PET/CT, systemic inflammation, and intramuscular adaptations. …”
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