Cross-species comparison of rodent and human decision-making in the Iowa Gambling Task in select neurological and psychiatric disorders: translational approach to examine age- and... by Varsha Singh, Manjari Tripathi, Sarat P. Chandra, Rohit Verma, Sushil Kumar Jha, Harvinder Singh Chhabra, Mrinmoy Chakravarty, Mrinmoy Chakravarty, Shambhovi Mitra, Indupriya B, Ankit Jha, Sakshi Sharma, Jyotsna Pandey, Divyanshi Pandey, Insha Shamshad, Ekta Ahlawat, Titli Saha, Chloé César, Suman Jain

“…This non-analogous structural–functional mapping of brain regions and cognitive deficits result in rodent models that fail to establish causal links of brain pathophysiology and clinical conditions, and the model remains a poor depiction of cognitive deficits experienced by humans. …”
Get full text

High-Dose Ceftriaxone in Elderly Patients with Enterococcal Infective Endocarditis: Population Pharmacokinetics of Free Ceftriaxone and Dose Optimization by Beatriz Fernández Rubio, Fernando Docobo Pérez, Laura Herrera Hidalgo, Luis Eduardo López-Cortés, Rafael Luque Márquez, José Manuel Lomas Cabezas, Luis Fernando López-Cortés, Marta Mejías Trueba, Ana Belén Guisado Gil, Alicia Gutiérrez Valencia, Arístides de Alarcón González, María Victoria Gil Navarro

“…Ceftriaxone free concentration was measured at three time-points: before the administration (C_min) and two and four hours after ceftriaxone administration (C₂ and C₄). Both structural and covariate population pharmacokinetic models were built. …”
Get full text

Ecological responses of Orientallactaga sibirica: Variations in body size and trophic niche across changing habitats by Qi-qige Buren, Xin Li, Guo-kang Chen, Guo-hui Ye, Shan-shan Sun, Yong-ling Jin, Ming-ming, He-Ping Fu, Shuai Yuan

“…The trophic niche width of O. sibirica varied across habitat types, being widest in the warm-temperate semi-humid zone and at mid-altitudes. Segmented structural equation modeling revealed that elevation and mean annual temperature exerted significant negative effects on O. sibirica body size by affecting FVC, whereas annual precipitation had a significant positive effect on body size, mediated through FVC. …”
Get full text

Kun–Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile by Yan Ma, Xingdong Chen, Jie Wei, Li Guo, Jian Huang, Li Xie, Lei Chen, Ping Lu, Wei Sun, Wei Shi, Feng Ding, Liping Zhang, Yue Zhang, Linlin Zhang, Rui Song, Yi Huang, Jun Shen, Hong Xu, Zhigang Chen, Qian Shen, Ying Ma, Yiwen Zhang, Hongxia Li, Yihui Zhai, Biao Xu, Xian Zhou, Jun Sun, Bing Wu, Rui Su, Xiaoyan Yu, Jianhong Zhu, Yihong Huang, Ling Gong, Nana Wu, Jingjing Sun, Tianyi Liu, He Yuan, Yiwen Shen, Jiaojiao Liu, Xia Han, Juanjuan Wu, Yinghua Sun, Suxiang Xu, Qinyi Zhang, Na Xie, Jianfeng Ji, Weizhi Mo, Yuanxin Liu, Xinghua Shi, Wanshan Qiu, Jiapeng Mi, Juhua Yan, Minghui Zhu, Pei Feng, Wenqian Sheng, Mingqin Tai, Chunqin Zhou, Qian Jin, Chengyu Gu, Xiujuan Huang, Qinfang Qian, Yixin Cao, Haochen Shen, Ziwen Xue, Yucui Ma, Juan Tian, Yingdan Zhang, Weiyuan Zhuang, Kaiqun Yang, Xiaohui Shen, Yanwei Gu, Beibei Shi, Chenhong Pan, Hongmei Zhou, Xiuchen Zhang, Meihua Tang, Kaixuan Gu, Hongping Liu, Yuanxian Li

“…Structured CKD questionnaires were administered, and biosamples (urine and dried blood spots) were obtained for the long-term storage and analysis using standard procedures. …”
Get full text

Comparative genetic mapping and a consensus interspecific genetic map reveal strong synteny and collinearity within the Citrus genus by Patrick Ollitrault, Patrick Ollitrault, Barbara Hufnagel, Barbara Hufnagel, Franck Curk, Aude Perdereau, Pierre Mournet, Pierre Mournet, Maëva Miranda, Maëva Miranda, Gilles Costantino, Yann Froelicher, Yann Froelicher, Mônica Alves, Maria Angeles Forner Giner, Malcolm W. Smith, Pablo Aleza, François Luro, Nelson A. Wulff, Leandro Peña, Raphaël Morillon, Raphaël Morillon, Arnaud Lemainque

“…The consensus genetic map is a useful tool to check the accuracy of genome assemblies, identify large structural variation and focus on analyzing potential relationships with phenotypic variations. …”
Get full text

Key Drivers Affecting the Future of Power Relations in Tehran Metropolis with a Scenario-Writing Approach by Afshin Mottaghi, Arash Ghorbani Sepehr, Joseph Saloukadz

“…The Delphi method was also used to screen the propellants. The data were analyzed using the MicMac and Scenario Wizard software. …”
Get full text

Design and analysis of spiral plating solution flow and rotating magnetic field device for electroplated diamond wire saw by Wei HUANG, Yanming HE, Jinbao XU, Zhenya SONG, Xiang HUANG, Yumeng SUN, Ximeng YU

“…The research focuses on solving three core problems: (1) the structural design of the spiral bath flow electroplating device and the optimization of flow rate and spiral speed of the spiral bath flow; (2) the structural design of the rotating magnetic field device and the optimization of rotation speed and magnetic field strength; (3) the optimal process parameters for electroplating diamond wire saws in the new composite field electroplating device, and the production of wire saws for silicon wafer cutting experiments.MethodsThe electroplating mixture spirals in the same direction around the baseline, which can improve the consistency of diamond particle concentration around the baseline circumference and enhance the uniformity of the mixed solution stirring. …”
Get full text

Metacognitive training (MCT) for psychosis: a systematic review and grade recommendations by Adrien Goncalves, Susana Ochoa, Steffen Moritz, Łukasz Gawęda, Alvaro Cavieres, Caroline König, Rabea Fischer, Antonia Meinhart, Maria Lamarca, Rosa Ayesa-Arriola, Ryan Balzan, Kerem Böge, Tania Lecomte, Stéphane Raffard, Fabrice Berna

Get full text

Abnormal Granger causal connectivity based on altered gray matter volume and associated neurotransmitters of adolescents with internet gaming disorder revealed by a multimodal neur... by Xiaoyu Niu, Mengzhe Zhang, Xinyu Gao, Jinghan Dang, Jieping Sun, Qiuying Tao, Yan Lang, Weijian Wang, Yarui Wei, Shaoqiang Han, Huayan Xu, Yingkun Guo, Jingliang Cheng, Yong Zhang

“…Therefore, we aimed to integrate structural, functional and molecular data to explore the GMV-based Granger causal connectivity abnormalities and their correlated neurotransmitter systems in IGD adolescents. …”
Get full text

Investigating the effects of a randomized, double-blinded aerobic, resistance, and cognitive training clinical trial on neurocognitive function in older adults with cardiovascular... by Louis Bherer, Louis Bherer, Louis Bherer, Tudor Vrinceanu, Emma Gabrielle Dupuy, Emma Gabrielle Dupuy, Mathieu Gayda, Thomas Vincent, Pierre-Olivier Magnan, Pierre-Olivier Magnan, Hanieh Mohammadi, Claudine Gauthier, Claudine Gauthier, Christine Gagnon, Simon Duchesne, Kirk I. Erickson, Daniel Gagnon, Frédéric Lesage, Sonia Lupien, Judes Poirier, Marie-Pierre Dubé, Éric Thorin, Martin Juneau, Juliana Breton, Sylvie Belleville, Sylvie Belleville, Guylaine Ferland, Guylaine Ferland, Flavie Gaudreau-Majeau, Flavie Gaudreau-Majeau, Caroll-Ann Blanchette, Caroll-Ann Blanchette, Paolo Vitali, Anil Nigam, Anil Nigam

“…Moreover, functional and structural cerebral mechanisms involved are still poorly documented. …”
Get full text

Biological contingency and adaptation to celibacy among girls aged 35 and over in Yazd city by Ahmad Kalateh Sadati, Fatemeh Jafari Naeimi, Sara Sadeghieh, Zahra Sadeghian Moghadam

“…The participants included 15 unmarried women aged 35 and older from Yazd, who were selected purposefully. Data were analyzed using a semi-structured interview method. …”
Get full text

Effects of nutritional counseling on dietary patterns in patients with mild cognitive impairment: insights from the BrainFit-Nutrition study by Etienne Hanslian, Etienne Hanslian, Melanie Dell’Oro, Julia K. Schiele, Julia K. Schiele, Farid I. Kandil, Farid I. Kandil, Dzenita Hasanbasic, Dzenita Hasanbasic, Cirus Henn, Elmar Graessel, Julia-Sophia Scheuermann, Petra Scheerbaum, Andreas Michalsen, Andreas Michalsen, Michael Jeitler, Michael Jeitler, Michael Jeitler, Michael Jeitler, Christian S. Kessler, Christian S. Kessler, Christian S. Kessler

“…While the primary outcome of the BrainFit-Nutrition study assessed the impacts of diet and cognitive training on cognitive performance, this secondary data analysis focuses on dietary habits and their changes over time. …”
Get full text

Antimicrobial resistance (AMR) and spread of New Delhi Metallo-β-Lactamase (NDM) in Italy: A call for policymakers by Gabriella Nucera

“…According to its Agenzia Regionale di Sanità (ARS) data, between November 2018 and 27 October 2019, NDM producing CREs have been identified in the blood of 129 patients and the rate of mortality in patients with sepsis was as 33% [13]. …”

Right atrial strain in Anderson–Fabry disease by Rosa Lillo, Rosa Lillo, Alessio Cianci, Maria Chiara Meucci, Giulia Iannaccone, Giulia Iannaccone, Claudio Di Brango, Filippo Tusa, Mario Marsilia, Gaetano Antonio Lanza, Gaetano Antonio Lanza, Antonella Lombardo, Antonella Lombardo, Francesco Burzotta, Francesco Burzotta, Francesca Graziani

“…BackgroundTo date, only limited data are available on right atrium (RA) morphofunctional remodeling in Fabry disease (FD).PurposeWe aimed to investigate RA structural and functional remodeling in patients with FD vs. healthy controls using 2D speckle tracking echocardiography (STE) and to explore whether any differences exist in FD patients with and without left ventricular hypertrophy (LVH).MethodsWe prospectively enrolled patients with FD and controls matched for age, sex, and cardiovascular risk factors. …”
Get full text

Multi-omics insights into functional alterations of the liver in growth-retarded offspring: transcriptomic, epigenetic and metabolomic profiles by Qun Lan, Sui Liufu, Xin Xu, Bohe Chen, Wenwu Chen, Kaiming Wang, Caihong Liu, Lanlin Xiao, Xiaolin Liu, Lei Yi, Jingwen Liu, Qiuchun Deng, Haiming Ma, Meng Kang

“…Finally, integrative analysis of RNA-seq and ATAC-seq data revealed several differentially accessible regions (DARs), which were annotated to the genes ACSL3, ITGA11, COL6A3, CYP2C49, and STXBP3. …”
Get full text

Safety of a co-designed cognitive behavioural therapy intervention for people with type 1 diabetes and eating disorders (STEADY): a feasibility randomised controlled trialResearch... by Marietta Stadler, Natalie Zaremba, Amy Harrison, Jennie Brown, Divina Pillay, Jacqueline Allan, Rachael Tan, Salma Ayis, Emmanouela Konstantara, Janet Treasure, David Hopkins, Khalida Ismail

“…Baseline mental health data (Structured Clinical Interview for DSM-5, SCID-5RV), and secondary biomedical outcomes (HbA1c; glucose time in range; TIR) and person-reported outcome measures (PROM: Diabetes Eating Problems Survey-Revised, DEPS-R; Eating Disorder Examination Questionnaire Short, EDE-QS; Type 1 Diabetes Distress Scale, T1DDS; Generalised Anxiety Disorder Assessment, GAD-7; Patient Health Questionnaire, PHQ-9; Impact of Diabetes Profile, DIDP) were collected. …”
Get full text

Exploring perceptions and preferences for PrEP choice and of an mHealth intervention: insights from the ImPrEP CAB‐Brasil study by Cristina Pimenta, Claudio G. Mann, Brenda Hoagland, Eduardo Carvalheira, Cristina Jalil, Marcos Benedetti, Nilo Fernandes, Carolina Coutinho, Emilia M. Jalil, Mayara Secco Torres Silva, Roberta Trefiglio, Alessandro Farias, Maria Paula G. Mourão, José Valdez Madruga, Josué N. deLima, Ronaldo Zonta, Gabrielle O'Malley, Valdilea G. Veloso, Beatriz Grinsztejn, Thiago S. Torres, for the ImPrEP CAB‐Brasil Study

“…A subset of participants from each site were invited to participate in the qualitative study (October 2023−July 2024). Semi‐structured interviews were conducted, recorded and transcribed. …”
Get full text

Bacteroides vesicles promote functional alterations in the gut microbiota composition by Olga Yu. Shagaleeva, Daria A. Kashatnikova, Dmitry A. Kardonsky, Boris A. Efimov, Viktor A. Ivanov, Svetlana V. Smirnova, Suleiman S. Evsiev, Eugene A. Zubkov, Olga V. Abramova, Yana A. Zorkina, Anna Y. Morozova, Elizaveta A. Vorobeva, Artemiy S. Silantiev, Irina V. Kolesnikova, Maria I. Markelova, Evgenii I. Olekhnovich, Maxim D. Morozov, Polina Y. Zoruk, Daria I. Boldyreva, Victoriia D. Kazakova, Anna A. Vanyushkina, Andrei V. Chaplin, Tatiana V. Grigoryeva, Natalya B. Zakharzhevskaya

“…According to the metabolome and sequencing data, the microbiota composition of the DSS-treated OMV group was intermediate between that of the control and DSS groups. …”
Get full text

The impact of aripiprazole on neurocognitive function in individuals at clinical high risk for psychosis: A comparison with olanzapine and non-antipsychotic treatment by JiaHui Zeng, Andrea Raballo, JiaYi Ye, YuQing Gao, WenJun Su, YanYan Wei, XiaoChen Tang, LiHua Xu, YeGang Hu, Dan Zhang, HuiRu Cui, YingYing Tang, XiaoHua Liu, HaiChun Liu, Tao Chen, ChunBo Li, JiJun Wang, TianHong Zhang

Get full text

Direct reactions with the AT-TPC by Yassid Ayyad, Daniel Bazin, Daniel Bazin, Francesca Bonaiti, Francesca Bonaiti, Jie Chen, Xiaobin Li, Adam Anthony, Melina Avila, Saul Beceiro-Novo, Khushi Bhatt, Cristina Cabo, Tatsuya Furuno, Valdir Guimarães, Alex Hall-Smith, Curtis Hunt, Heshani Jayatissa, Takahiro Kawabata, Harriet Kumi, Jose Manuel López-González, Juan Lois-Fuentes, Augusto Macchiavelli, Gordon McCann, Claus Müller-Gatermann, Alicia Muñoz-Ramos, Wolfgang Mittig, Wolfgang Mittig, Bruno Olaizola, Zarif Rahman, Daniel Regueira, Javier Rufino, Soki Sakajo, Clementine Santamaria, Michael Z. Serikow, Michael Z. Serikow, Tianxudong Tang, Tianxudong Tang, Ivan Tolstukhin, Nathan Turi, Nathan Turi, Nathan Watwood, Juan Zamora

“…The necessity of using inverse kinematics to reveal how these structural properties change with isospin imbalance renders direct reactions a challenging technique when using the missing mass method.MethodsIn this scenario, Active Target Time Projection Chambers (AT-TPC) have demonstrated an outstanding performance in enabling these types of reactions even under conditions of very low beam intensities. …”
Get full text