Development and Assessment of a New Multichannel Electrocutaneous Device for Non-Invasive Somatosensory Stimulation for Magnetic Resonance Applications by Carolina Travassos, Alexandre Sayal, Paulo Fonte, Bruno Direito, Luis Lopes, Nuno Carolino, Sonia Afonso, Tania Lopes, Teresa Sousa, Miguel Castelo-Branco

“…Next, the device’s capacity to generate perceptible tactile sensations and user acceptability were assessed by testing the device on a single participant outside the MR environment. Finally, structural and functional data were acquired from three participants during a somatosensory stimulation experiment as a proof of concept to confirm the brain activity elicited by stimulation. …”
Get full text

Gymnadenia conopsea orchid: a systematic review by Jing-Yi Wu, Jing-Yi Wu, Ruo-Nan Tang, Ruo-Nan Tang, Jia-Wen Wang, Jia-Wen Wang, Wan-Ying Chen, Wan-Ying Chen, Xing Liu, Ji-Wen Wang, Mei-Ya Li, Fu-Sheng Jiang, Fu-Sheng Jiang

“…Current propagation efforts face significant challenges, including low natural germination rates, and dependence on specific habitats and obligate mycorrhizal fungi, precluding the development of efficient large-scale cultivation and seedling production systems.ConclusionMarked progress has been made in characterizing small-molecule metabolites of G. conopsea, yet comprehensive structural elucidation of polysaccharides remains incomplete. …”
Get full text

Peer support enhanced behavioural crisis response teams in the emergency department: protocol for a stepped-wedge cluster-randomised controlled trial by Ambrose H Wong, James D Dziura, Mark Sevilla, Yue Hu, Megan Evans, Bidisha Nath, Rebekah Heckmann, Riddhi Desai, Anusha Kumar, Isaac V Faustino, Anthony J Pavlo, Joan M Cook, Kendra Davis-Plourde, Richard Youins, Kimberly Guy, Pastor Evelyn Smith, Pastor Dana Smith, Karen Kangas, Lou Hart, Seth Powsner, Chyrell Bellamy

“…The PACT intervention will integrate peer delivery of trauma-informed care within a structured, interprofessional, team-based response protocol for behavioural crisis management. …”
Get full text

Parental perceptions of a wearable vital signs monitor for observation of newborns: in-depth interviews in three tertiary hospitals, Southwest Nigeria by Yetunde Olufisayo John-Akinola, Adejumoke Idowu Ayede, Ayomide Adeyemi, Assumpta Nantume, Adesewa Oluwatomisin Olaleye, Olugbenga Akinrinoye, Olukemi Oluwatoyin Tongo, Michael Abe Alao, Adenike Oluleye, Oluseye Sobande, Olatayo Sunday Olayemi, Bertha Akinyi Oketch, Rosena Olubanke Oluwafemi, Rosena Olubanke Oluwafemi, Patricia Ireti Eniowo, Samuel Ojo, Omolayo Adebukola Olubosede, Emmanuel Olaseinde Bello, Ismaila Sani, Teresa Cauvel, Sona Shah

“…Interviews were moderated with a semi-structured interview guide and audio recorded. Data were transcribed, coded and analyzed thematically using NVivo software.ResultsThe majority of participants expressed positive reactions to the neoGuard device, although some initial concerns were reported. …”
Get full text

OP-13 CHOLANGIOCARCINOMA IN LATIN AMERICA: A MULTICENTER OBSERVATIONAL STUDY ALERTS ON ETHNICAL DISPARITIES IN TUMOR PRESENTATION AND OUTCOME by Leonardo G Da Fonseca, Laura Izquierdo Sanchez, Pedro H Hashizume, Yanina Carlino, Estefanía Liza Baca, Cristina Zambrano, Santiago Sepulveda, Andrea Bolomo, Pedro M Rodrigues, Ioana Riaño, Andre Boonstra, Jose D Debes, Luis Bujanda, Flair J Carrilho, Marco Arrese, Juan C Roa, Enrique Carrera, Javier Díaz Ferrer, Domingo Balderramo, Claudia P Oliveira, Jesus M Banales

“…These findings highlight structural challenges in cancer screening and healthcare access among diverse ethnic backgrounds and lower socioeconomic statuses in the region. …”
Get full text

Mapping grey matter and cortical thickness alterations associated with subjective cognitive decline and mild cognitive impairment among rural-dwelling older adults in China: A popu... by Ziwei Chen, Qianqian Xie, Jiafeng Wang, Yan Wang, Huisi Zhang, Chunyan Li, Yongxiang Wang, Lin Cong, Shi Tang, Tingting Hou, Lin Song, Yifeng Du, Chengxuan Qiu

“…Background: The structural brain alterations for subjective cognitive decline (SCD) and mild cognitive impairment (MCI) are poorly defined. …”
Get full text

Knowledge, attitudes, and referral practices regarding animal bites and prevention of human rabies among Traditional Health Practitioners in the eThekwini District in KwaZulu-Natal... by Maxwell Mabona, Maxwell Mabona, Maxwell Mabona, Thembekile Zwane, Babongile Mhlongo, Lazarus Kuonza, Lazarus Kuonza, Poncho Phafane, Poncho Phafane

“…Our study aimed to assess the knowledge, attitudes, and referral practices regarding human rabies and the associated factors among THPs in eThekwini District, KwaZulu-Natal.MethodsA cross-sectional study was conducted among registered THPs in eThekwini District, collecting data through a structured, standardized questionnaire. …”
Get full text

Human gut microbiota adaptation to high-altitude exposure: longitudinal analysis over acute and prolonged periods by Xianzong Ma, Changwei Duan, Xiaoying Wang, Yurong Tao, Lang Yang, Yongsheng Teng, Yuanming Pan, Mingjie Zhang, Junfeng Xu, Jianqiu Sheng, Xin Wang, Peng Jin

“…In summary, acute high-altitude exposure caused dramatic changes in gut microbiota, while prolonged exposure led to structural and functional reshaping. These findings enhance our understanding of how high-altitude environments reshape gut microbiota.IMPORTANCEThis study is the first to investigate the impact of high-altitude exposure on gut microbiota adaptation in a large-scale longitudinal cohort. …”
Get full text

A qualitative study on the experience of nurses in the health education for patients with ulcerative colitis based on the Ottawa decision support framework (基于渥太华决策支持框架的护士参与溃疡性结肠炎患... by LIANG Zhuolin (梁琢琳), LI Xumiao (李旭苗), WEI Rongsai (魏荣赛), LIU Jingying (刘璟莹), ZHANG Nan (张楠), MA Hongwen (马宏文)

“…Through purposive sampling, semi-structured interviews were conducted with 11 nurses from the Department of Gastroenterology. …”
Get full text

Magnetic Resonance Imaging as a Readout of CLN5 Gene Therapy Efficacy in Sheep by Samantha J. Murray, Mustafa M. Almuqbel, Simon A. Felton, Nickolas J. Palmer, Ashley R. Deane, Daniel J. Myall, Reza Shoorangiz, Arsène Ella, Matthieu Keller, David N. Palmer, Tracy R. Melzer, Nadia L. Mitchell

“…Method Sheep treated at a pre‐symptomatic timepoint underwent five T1‐weighted structural MRI scans between 5 and 18 months of age. …”
Get full text

Genetic influences on the association between DNA methylation and obesity measures: insights from a twin study design by Xuanming Hong, Hui Cao, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Runhua Hu, Ruqin Gao, Min Yu, Jinyi Zhou, Xianping Wu, Yu Liu, Shengli Yin, Wenjing Gao, Liming Li

“…Despite more than a thousand of obesity-related DNAm sites (CpGs) being identified, studies that account for genetic influences in these associations are limited. Results Using data from 1,074 twins in the Chinese National Twin Registry and bivariate structural equation models (SEMs), we investigated the phenotypic (Rph), genetic (Ra), and environmental (Re) correlations between genome-wide DNAm and three obesity indices: BMI, waist circumference (WC), and waist-to-hip ratio (WHR). …”
Get full text

The Boost Team: transforming outreach for female veterans in rural communities by Jenny Krause Cohen, Jenny Krause Cohen, Kara Zamora-Rogoski, Caitlin McLean, Mariam Jacob, Tara Stacker, Caroline Dancu, Caroline Dancu, Jennifer Childers

“…Of Veterans who received the outreach, 58 completed a telephone survey using the Patient Empowerment Engagement Activation Survey (PEEAS), and 21 completed a semi-structured interview. Interviews focused on experiences with the NP, Boost's impact on access to and experience of VHA care, and suggestions for program improvement. …”
Get full text

Prevalence of blood-borne virus infections and uptake of hepatitis C testing and treatment in Australian prisons: the AusHep studyResearch in context by Rugiatu Bah, Yumi Sheehan, Xiaoying Li, Gregory J. Dore, Jason Grebely, Andrew R. Lloyd, Behzad Hajarizadeh, Andrew Lloyd, Behzad Hajarizadeh, Yumi Sheehan, Rugi Bah, Charlotte Li, Marianne Byrne, Tony Butler, Bridget Musarurwa, Elmira Hooshmand, Annabeth Simpson, Meya Alrayyani, Jason Grebely, Greg Dore, Nikki Price, Melissa Groom

“…Methods: Randomly-selected participants from 23 representative prisons nationally were offered point-of-care testing for HIV and HCV (anti-HCV) antibodies, hepatitis B surface antigen (HBsAg), and HCV RNA (if anti-HCV positive). Demographic data and previous HCV testing and treatment were collected by structured interview. …”
Get full text

Prospectively investigating the impact of AI on shared decision-making in post kidney transplant care (PRIMA-AI): protocol for a longitudinal qualitative study among patients, thei... by Peter Dabrock, David Samhammer, Zeineb Sassi, Sascha Eickmann, Sebastian Möller, Roland Roller, Bilgin Osmanodja, Aljoscha Burchardt, Klemens Budde, Anne Herrmann

“…Assuming a dropout rate of 20% per year, it is anticipated that 30 patient–SP dyads will be included in the last follow-up with the aim of achieving data saturation. Interviews will be audio-recorded and transcribed verbatim. …”
Get full text

Rationale and methodology of a multicentric prospective cohort study on ‘Longitudinal Effects of Air Pollution Exposure on Adolescent Lungs (APEAL)’ in urban India: APEAL protocol... by George D’Souza, Anant Mohan, Padukudru Anand Mahesh, Amruta Nori-Sarma, Harish C Phuleria, Gregory Wellenius, Twinkle Agrawal, Rajesh Thimmulappa, Biligere Siddaiah Jayaraj, Minu Rose Mani, Swapnali Patil, Priya Samdarshi

“…After quality checks, data will be compiled, summarising pulmonary function parameters alongside covariates and confounders. …”
Get full text

An inner membrane complex protein IMC1g in Plasmodium berghei is involved in asexual stage schizogony and parasite transmission by Yinjie Liu, Shitong Cheng, Gang He, Dawei He, Duo Wang, Sicong Wang, Lumeng Chen, Liying Zhu, Yonghui Feng, Liwang Cui, Yaming Cao, Xiaotong Zhu

“…Additionally, we confirmed that IMC1g is functionally conserved in Plasmodium spp. These data reveal the function of IMC1g protein in anchoring the glideosome, providing further insight into the mechanism of the glideosome function.…”
Get full text

Capsaicin induces ferroptosis via suppression of SLC7A11 activity and upregulation of ACSL4 mediated by AMPK in tongue squamous cell carcinoma by Qiwei Zhao, Qiwei Zhao, Yu Wang, Yu Wang, Long Ding, Long Ding, Zhuang Li, Zhuang Li, Mengyang Wang, Yueqing Huang, Qiushi Cao, Qiushi Cao, Yaqin Sun, Yaqin Sun, Xiaohong Guo, Xiaohong Guo

“…In this study, we aimed to validate whether CAP induces ferroptosis in TSCC and to elucidate the underlying mechanisms.MethodsCell viability in HN6 and CAL27 cells was assessed using CCK-8 assays. Mitochondrial structural changes were observed via transmission electron microscopy (TEM). …”
Get full text

“They look you up and down like you are nothing”: A qualitative exploration of sex workers’ health needs and interactions with UK healthcare services by E. Molloy, R. Tiwana, B.c French, C. Christie, H. Smailes, J. Taylor, C. Bradbury-Jones

“…Methods: We undertook semi-structured interviews which explored healthcare needs and access for sex workers. …”
Get full text

Relative vacuum reduction innovative processes applied in primary magnesium production—Comprehensive analysis of thermodynamics, resource, energy flow, and carbon emission by Xiaolong Li, Tingan Zhang, Yan Liu, Junhua Guo, Jingzhong Xu, Yuanyuan Liang

“…Magnesium and magnesium alloys, serving as crucial lightweight structural materials and hydrogen storage elements, find extensive applications in space technology, aviation, automotive, and magnesium-based hydrogen industries. …”
Get full text

Cardiac myosin binding protein C correlate with cardiac troponin I during an exercise training program in patients with HFrEF by E. Riveland, A. Ushakova, T. Valborgland, T. Karlsen, H. Dalen, E. Prescott, T. Omland, A. Linke, M. Halle, M. Marber, Ø. Ellingsen, A.I. Larsen, the SMARTEX‐HF Study Group

“…As the training load in the two intervention arms was similar, these patients were merged and constituted the intervention group (IG). Clinical data and measurements were obtained at baseline and at 12 weeks. …”
Get full text