Development and Application of a Senolytic Predictor for Discovery of Novel Senolytic Compounds and Herbs by Jinjun Li, Kai Zhao, Guotai Yang, Haohao Lv, Renxin Zhang, Shuhan Li, Zhiyuan Chen, Min Xu, Naixue Yang, Shaoxing Dai

“…In the DrugBank database, 98 structurally novel candidate compounds with potential senolytic activity were identified. …”
Get full text

Artificial Intelligence in Breast Cancer Diagnosis and Treatment: Advances in Imaging, Pathology, and Personalized Care by Petar Uchikov, Usman Khalid, Granit Harris Dedaj-Salad, Dibya Ghale, Harney Rajadurai, Maria Kraeva, Krasimir Kraev, Bozhidar Hristov, Mladen Doykov, Vanya Mitova, Maria Bozhkova, Stoyan Markov, Pavel Stanchev

“…However, challenges include data variability, ethical concerns, and real-world validation. …”
Get full text

South Africa’s male homicide epidemic: Who is killing men and why do we ignore the victims? by Richard Matzopoulos, Morna Cornell, Brett Bowman, Lorna J. Martin, Rachel Jewkes, Naeema Abrahams

“…Broad population-based approaches are required to address the insidious effect of recalcitrant societal norms and structural interventions to overcome the root causes of poverty and inequality and the poor control of alcohol and firearms. …”
Get full text

Understanding community pharmacists’ intentions to report adverse drug reactions in Saudi Arabia: a theory of planned behavior analysis by Fahad T. Alsulami, Yousef Saeed Alqarni, Wadia Saad Alruqayb, Mohammed S. Alharthi, Mohammad S. Alzahrani, Majed A. Algarni, Musaad M. Althobaiti, Saad Mohammed Almalki, Nawaf Abid Altowarqi, Hussain Ali Mathkur, Anas Muslih Althumali, Ayman Mohammed Alharthi, Haifa Abdulrahman Fadil, Adel A. Altowairqi, Mubarak S. Alharthi

“…Strategies such as structured training, institutional support, and promoting moral responsibility may bridge the gap between awareness and actual reporting practices among community pharmacists in Saudi Arabia.…”
Get full text

Discriminant analysis of occupational performance characteristics in patients with major depressive disorders and healthy individuals by Tomonari Hayasaka, Izumi Nagashima, Miku Hoshino, Koji Teruya, Yasuyuki Matumoto, Masami Murao, Taku Maruki, Masako Watanabe, Takeshi Katagiri, Yayoi Imamura, Mariko Kurihara, Yuki Oe, Yoshikazu Takaesu, Takashi Tsuboi, Koichiro Watanabe, Hitoshi Sakurai

“…Abstract Aim Assessing symptoms and daily functioning in patients with major depressive disorder (MDD) can be challenging, as their limited self‐monitoring abilities may result in behavior observed during structured interviews not accurately reflecting their daily lives. …”
Get full text

Effects of Mg-Palygorskite Modified Biochar on the Growth of <i>Sedum alfredii</i> Hance in Heavy Metal Contaminated Soil by Tianwen Wang, Xianxiang Luo, Kun Chen, Hao Zheng, Zewei Song, Lize Zhao, Junhua Gong, Fengmin Li, Ruhai Liu

“…This study provides data support for the development of functionalized biochar for the remediation of heavy metal pollution in soil.…”
Get full text

Sex differences in the association of Alzheimer’s disease biomarkers and cognition in a multicenter memory clinic study by Cecilia Boccalini, Debora Elisa Peretti, Max Scheffler, Linjing Mu, Alessandra Griffa, Nathalie Testart, Gilles Allali, John O. Prior, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Giovanni B. Frisoni, Valentina Garibotto

“…Methods 249 participants (females/males:123/126), who underwent tau-PET, amyloid-PET, structural MRI, and plasma glial fibrillary acidic protein (GFAP) measurement were included from Geneva and Lausanne Memory Clinics. …”
Get full text

Cognition and experience of surgical incisions in patients undergoing laparoscopic surgery with enhanced recovery after surgery protocol: A qualitative study by Hongxia Xu, Yihong Xu, Gongjie Shi, Jiaqi Lu, Liping Zhu, Guibing He, Xiao Liang

“…The data were analyzed via the framework method to identify themes related to incision experiences. …”
Get full text

Anti-HIV-1 Effect of the Fluoroquinolone Enoxacin and Modulation of Pro-Viral hsa-miR-132 Processing in CEM-SS Cells by Verena Schlösser, Helen Louise Lightfoot, Christine Leemann, Seyedeh Elnaz Banijamali, Aathma Merin Bejoy, Shashank Tiwari, Jeffrey L. Schloßhauer, Valentina Vongrad, Andreas Brunschweiger, Jonathan Hall, Karin J. Metzner, Jochen Imig

“…Results: We established that Enoxacin, but not the structurally similar compound nalidixic acid, exhibits strong anti-HIV-1 effects in the T-cell line CEM-SS, but not MT-4. …”
Get full text

Longitudinal Multimodal Magnetic Resonance Imaging Reveals Improvement in Verbal Fluency Over Time in Moderate-to-Severe Traumatic Brain Injury by Ana Luiza Zaninotto, Fabiola Macruz, Fabricio S. Feltrin, Celi S. Andrade, Claudia C. Leite, Vinicius Monteiro de Paula Guirado, Wellingson S. Paiva, Sylvain Bouix

“…Twenty-one adults with moderate and severe DAI were analyzed. Structural and diffusion data were acquired on a 3T system 3 and 6 months after the injury. …”
Get full text

Climate, soil and management factors drive the quantitative relationships between soil fertility and spring maize water productivity in northern China by Jiao Shi, Minggang Xu, Xinhua He, Huaiping Zhou, Jianhua Li

“…The random forest, partial least squares structural equation modeling and variance partitioning analysis were then applied to address the quantitative relationships (QRs) and relevant differences. …”
Get full text

Women's experiences and acceptability of self-administered, home delivered, intravaginal 5-Fluorouracil cream for cervical precancer treatment in Kenya by Konyin Adewumi, Aparna Ghosh Kachoria, Everlyn Adoyo, Mercy Rop, Mercy Rop, Antony Owaya, Jennifer H. Tang, Jennifer H. Tang, Lisa Rahangdale, Lisa Rahangdale, Lisa Rahangdale, Chemtai Mungo, Chemtai Mungo, Chemtai Mungo

“…Quantitative data were analyzed using descriptive statistics. …”
Get full text

Feasibility of a tailored, combined intervention with mind-body elements to prevent burnout in healthcare professionals (LAGOM) in a mixed-methods multicenter single-arm trial by Marleen Schröter, Anna K. Koch, Julia Berschick, Julia K. Schiele, Martin Bogdanski, Melanie Steinmetz, Judith Czakert, Wiebke Stritter, Christian S. Kessler, Georg Seifert

“…The feasibility of electrophysiological measures like pulse and respiration activity was assessed. Semi-structured interviews with a subgroup were qualitatively analyzed following a qualitative content analysis approach. …”
Get full text

Engagement in hepatitis C virus cascade of care and factors associated with testing among people who inject drugs in Iran by Mehrdad Khezri, Fatemeh Tavakoli, Soheil Mehmandoost, Heidar Sharafi, Omid Zamani, Maliheh Sadat Bazrafshani, Naser Nasiri, Hossein Mirzaei, Hossein Moameri, Ali Akbar Haghdoost, Courtney McKnight, Don Des Jarlais, Mohammad Karamouzian, Hamid Sharifi

“…Methods We recruited PWID in 14 cities using respondent-driven sampling. PWID completed structured interviews capturing measures on socio-demographics, behaviors, and HCV CoC. …”
Get full text

Factors associated with the dietary total antioxidant capacity of pregnant Brazilian women by Roberta Rejane Santos de Carvalho, Poliana Cristina de Almeida Fonseca Viola, Sandra Patrícia Crispim, Ana Karina Teixeira da Cunha França, Anderson Marliere Navarro, Bruno Feres de Souza, Franciane Rocha de Faria, Naiara Sperandio, Nathalia Pizato, Mariana de Souza Macedo, Renata Junqueira Pereira, Sylvia do Carmo Castro Franceschini, Carolina Abreu de Carvalho, Anderson Marliere Navarro, Carolina Abreu de Carvalho, Danielle Góes da Silva, Franciane Rocha de Faria, Naiara Sperandio, Jorge Gustavo Velásquez Meléndez, Míriam do Carmo Rodrigues Barbosa, Nathalia Pizato, Mariana de Souza Macedo, Renata Junqueira Pereira, Sandra Patrícia Crispim, Silvia Eloiza Priore, Sylvia do Carmo Castro Franceschini

“…Methods: A cross-sectional study with 2,232 pregnant women aged 18 years old or older, in the first, second, and third trimesters of pregnancy, from eleven cities in the five Brazilian regions. A semi-structured questionnaire was applied to assess socioeconomic, demographic, and health data, and a 24-hour dietary recall (R24h) was used to assess food consumption and analyze the dietary total antioxidant capacity (DTAC), estimated using the ferric reducing antioxidant power (FRAP) method. …”
Get full text

PLB2Tau mice are impaired in novel and temporal object recognition and show corresponding traits in brain MRI by Jacques Micheau, Gwenaelle Catheline, Elodie Barse, Bassem Hiba, Anne Marcilhac, Michèle Allard, Bettina Platt, Gernot Riedel

“…Upon completion of their behavioural testing, animals were recorded in a 7 T MRI for brain structural integrity and diffusion tensor imaging (DTI) analysis. …”
Get full text

Cardiovascular resource utilization in patients with diastolic dysfunction: A retrospective cohort analysis by Ato Howard, Paulomi Gohel, Virginia Singla, Aditi Naniwadekar, Floyd Thoma, Suresh Mulukutla, Aditya Bhonsale, Krishna Kancharla, Andrew Voigt, Alaa Shalaby, N.A. Mark Estes, III, Sandeep Jain, Samir Saba

“…HCRU included cardiac interventional, structural, surgical, and electrophysiology procedures, as well as diagnostic monitoring and imaging tests. …”
Get full text

Zipper-interacting protein kinase mediates neuronal cell death and cognitive dysfunction in traumatic brain injury via regulating DEDD by Yingxue Mei, Fei She, Ling Zhang, Gamin Kim, Ruomeng Li, Xiuzhi Zheng, Zonghai Wang, Renxuan Chen, Long Wang, Dongmei Chen, Jungho Kim, Tao Zhang, Tae Ho Lee

“…Abstract Neuronal cell death is a causative process in traumatic brain injury (TBI)-induced structural and functional impairment of the central nervous system. …”
Get full text

Patients’ acceptability and implementation outcomes of a case management approach to encourage participation in colorectal cancer screening for people with schizophrenia: a qualita... by Tempei Miyaji, Yosuke Uchitomi, Hiroyuki Okada, Masatoshi Inagaki, Maiko Fujimori, Taichi Shimazu, Masaki Fujiwara, Masafumi Kodama, Ryuhei So, Takanori Matsushita, Yusaku Yoshimura, Shigeo Horii, Hirokazu Takahashi, Naoki Nakaya, Shiro Hinotsu, Keita Harada, Norihito Yamada, Yuto Yamada, Tsuyoshi Etoh

“…In addition, three out of six providers were included.Data collection and analysis Using a structured interview, the case manager asked participants about patient acceptability and the helpful components of the intervention. …”
Get full text

Parental predictors of childhood vaccination adherence in border areas of Southern Vietnam: a first look at minority communities by An Dai Tran, Charuai Suwanbamrung, Muhammad Haroon Stanikzai, Nirachon Chutipattana, Shamarina Shohaimin, Patthanasak Khammaneechan, Le Minh Luan, Tran Phu Dien, Truong Thanh Nam, Phan Thanh Tung, Cua Ngoc Le

“…A total of 449 ethnic minority parents with children under five years old participated. Data were gathered through face-to-face household interviews using a structured questionnaire, complemented by direct observation of the children’s vaccination cards to verify adherence. …”
Get full text