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52921
Efficacy and safety of cannabidiol in a single-center pediatric drug-resistant epilepsy cohort: a retrospective study
Published 2025-07-01“…Clinical, demographic, and instrumental data were retrospectively extracted from the medical records and caregivers’ reports. …”
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52922
Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture in vitro intestinal model
Published 2025-08-01“…In-depth characterization by real-time PCR, flow cytometry, functional assay and electron microscopy showed that only butyrate and dibutyryl-cAMP generated phenotypically distinct eosinophilic cells with different activation statuses, marked by differential expression of surface markers CD11c and CD62L, increased expression of eosinophil specific genes, and development of eosinophilic structural features. Then, a triple-culture system encompassing the enterocytic cell line Caco-2 and the secretory cell line HT29-MTX complemented with eosinophilic differentiated cells was established. …”
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52923
Feasibility study of single-image super-resolution scanning system based on deep learning for pathological diagnosis of oral epithelial dysplasia
Published 2025-03-01“…Both the DS30R and Nikon scanners demonstrate high sensitivity and specificity for detecting structural features in OED pathological images; however, DS30R excels at identifying certain cellular features. …”
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52924
Quality of Surface and Groundwater in the Sierra de Amula Region, Jalisco, Mexico
Published 2025-01-01“…Each sample was evaluated for its pH, electrical conductivity, and ionic concentration (Ca<sup>2+</sup>, Mg<sup>2+</sup>, Na<sup>+</sup>, K<sup>+</sup>, CO<sub>3</sub><sup>2</sup><sup>−</sup>, HCO<sub>3</sub><sup>−</sup>, CI<sup>−</sup>, SO<sub>4</sub><sup>2−</sup>). For data analysis, we determined the ionic concentrations and the salinity and sodicity indexes, including the electrical conductivity, pH, sodium adsorption ratio (SAR), and cationic ratio of soil structural stability (CROSS). …”
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52925
The accumulation characteristics and exploration potential of oil and gas in the back-arc basin of Japan under the background of high heat flow
Published 2023-10-01“…The trap types are mainly structural traps, lithologic traps and composite traps. …”
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52926
Tagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing
Published 2024-07-01“…Abstract Background The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genotyping of abundant varieties towards accurate identification, management, and exploitation of germplasm resources. …”
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52927
Prognostic impact of small size sutureless prostheses: results for 241 patients from an international registry
Published 2025-07-01“…At a maximum follow-up of 8.1 years, 10 cardiovascular deaths, 4 valve related reinterventions (3 structural valve deterioration (SVD) requiring TAVI Valve-in-Valve, 1 endocarditis) occurred. …”
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52928
Epithelial-to-mesenchymal transition is an active process in the large airways of patients with asthma-COPD overlap and partially abrogated by inhaled corticosteroid treatment: a b...
Published 2025-05-01“…Additionally, the degree of RBM fragmentation was evaluated, a key tissue structural marker of EMT.ResultsCompared to healthy controls and asthmatics, ACO had the greatest fragmentation of RBM (P < 0.01). …”
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52929
Co-circulation and genetic characterization of genotype I and II feline bocavirus strains in domestic cats from Northern Vietnam
Published 2025-06-01“…DNA was extracted and screened for FBoV using conventional polymerase chain reaction targeting the non-structural (NS)-1 gene. Positive samples were subjected to Sanger sequencing, and partial NS1 sequences were analyzed using MEGA X for phylogenetic inference. …”
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52930
Cultural and behavioral drivers of zoonotic disease transmission and persistence among diverse pastoralist communities in East Africa
Published 2025-07-01“…Methods This study adopts a One Health approach, employing a range of participatory methods including informal observations, “go-along interviews,” narrative-, and key informant- interviews, to explore the cultural, behavioral, and structural drivers of zoonotic disease transmission among pastoralist communities in East Africa. …”
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52931
Efficacy and mechanisms underlying MRI-guided high-definition transcranial direct current stimulation for depression among university students: study protocol for a stepped wedge c...
Published 2025-07-01“…All groups will be receiving active intervention in week 5. Structural MRI data for each participant will be acquired to select the optimal electrode placement and correct for individual anatomical differences. …”
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52932
The association between the gut microbiome and antituberculosis drug-induced liver injury
Published 2025-03-01“…At the same time, we constructed mouse models to explore the effects of different anti-tuberculosis drugs on gut microbiota.ResultsFollowing anti-TB treatment, we observed a decrease in microbial diversity and significant structural changes in the gut microbiota of TB patients (P < 0.05). …”
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52933
Hsa_Circ_0105596/FTO inhibits progression of Parkinson's disease by sponging miR-187-3p and regulating eEF2
Published 2024-12-01“…The binding regulation relationship between circFTO-miR-187-3p-EEF2 was determined through structural analysis, RIP, and dual luciferase reporter assay. …”
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52934
Suppression of the T-dependent antibody response following oral exposure to selected polycyclic aromatic compounds in B6C3F1/N mice
Published 2025-03-01“…Careful characterization of strong positive and clear negative PACs is needed in order to lay the foundation for generating robust immunotoxicity data for structurally diverse PACs that have not yet been evaluated.MethodsIn the current study, adult B6C3F1/N female mice were treated daily for 28 consecutive days by oral administration of B(a)P to provide dose levels ranging between 2 and 150 mg/kg bodyweight/day. …”
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52935
Exploring the Strong Interaction of Three-Body Systems at the LHC
Published 2024-09-01“…The analysis of the p-d correlation shows that only a full three-body calculation that accounts for the internal structure of the deuteron can explain the data. In particular, the sensitivity of the observable to the short-range part of the interaction is demonstrated. …”
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52936
Correlates of duration between initial drug use and first drug injection among people who inject drugs in Iran, 2020
Published 2025-04-01“…Policymakers should prioritize evidence-based, multi-faceted approaches that target both individual and structural factors to delay or prevent the transition to injection drug use and reduce associated health risks.…”
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52937
Search for e + e − → K S 0 K S 0 h c $$ {K}_S^0{K}_S^0{h}_c $$
Published 2025-05-01“…Abstract Using e + e − collision data at 13 center-of-mass energies ranging from 4.600 to 4.951 GeV collected with the BESIII detector, we conduct the first search for the e + e − → K S 0 K S 0 h c $$ {K}_S^0{K}_S^0{h}_c $$ process and investigate the resonance structures in the cross section line shape. …”
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52938
Social networks, environmental, and individual factors associated with COVID-19 vaccination and booster uptake– The prospective PRIME cohort study
Published 2025-03-01“…Methods: In the PRIME longitudinal cohort study, we used online questionnaires to collect baseline data at the end of 2021, including participants' COVID-19 vaccination status and various factors, i.e., structural and functional social network characteristics (interpersonal factors), societal (social and physical living environment) community (work and social participation), and individual (sociodemographics, health) factors. …”
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52939
A Rare Case of Exophiala Dermatitidis Isolation in a Patient with Non-Cystic Fibrosis Bronchiectasis: Colonization or True Infection?
Published 2025-06-01“…<b>Discussion:</b> This case underscores the diagnostic challenges in distinguishing fungal colonization from true infection in structurally abnormal lungs. In NCFB, disrupted mucociliary clearance and microbial dysbiosis may facilitate fungal persistence, even in the absence of overt immunosuppression. …”
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52940
The mediating role of professional values and self-efficacy in the relationship between organizational justice and quality of working life among nurses in southwestern Iran
Published 2025-04-01“…To perform structural equation modeling (SEM) considering the sample size, we used Smart PLS version 4, and to determine the role and strength of the mediating effects of professional values and self-efficacy, we utilized Sobel tests and the Variance Accounted For (VAF) statistic. …”
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