Structural and Functional Characterization of the Most Frequent Pathogenic PRKN Substitution p.R275W by Bernardo A. Bustillos, Liam T. Cocker, Mathew A. Coban, Caleb A. Weber, Jenny M. Bredenberg, Paige K. Boneski, Joanna Siuda, Jaroslaw Slawek, Andreas Puschmann, Derek P. Narendra, Neill R. Graff-Radford, Zbigniew K. Wszolek, Dennis W. Dickson, Owen A. Ross, Thomas R. Caulfield, Wolfdieter Springer, Fabienne C. Fiesel

“…The functional analysis was accompanied by structural investigation of PRKN p.R275W. We observed lower PRKN protein in fibroblasts with compound heterozygous p.R275W mutations. …”
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Role of air pollution exposure in the alteration of brain cortical structure: A Mendelian randomization study by Chaojuan Huang, Zimei Cheng, Xu Wu, Zhiwei Li, Mingxu Li, Xingliang Feng, Yuyang Zhang, Qian Zhao

“…Conclusions: Our exploration established causal relationships between air pollution exposure and brain cortical structure, underscoring the significance of mitigating air pollution to preserve brain cortical morphology.…”
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Phylogenetic Structure Shifts Across Life-History Stages in Response to Microtopography and Competition in Subtropical Forests by Weiqi Meng, Haonan Zhang, Lianhao Sun, Jianing Xu, Yajun Qiao, Haidong Li

“…This study focuses on a subtropical evergreen broad-leaved forest in China, utilizing a large permanent plot established in the Yaoluoping National Nature Reserve. By integrating data from a full-stem census and total station surveying, we analyzed the phylogenetic structure of the plant community as a whole and across different life-history stages (saplings, juveniles, and adults) while quantitatively assessing microtopographic variables and an interspecific competition index. …”
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Re-Os age of molybdenite from the Hannivka deposit, Kryvyi Rih structure, Ukrainian Shield by Yu. Ye. Khomych, V. V. Sukach, L. V. Shumlyanskyy, S. M. Bondarenko, V. O. Syomka, S. Tessalina, M. M. Reshetnyk

“…These events were active in the Inhul megablock and expressed themselves in the Kryvyi Rih-Kremenchuk suture zone and Kryvyi Rih structure through the intrusion of veins and lenses of Kropyvnytskyi granitoid complex (dated at 1959 ± 36 Ma) and aplite-pegmatoid granites (dated at 1.8 Ga).…”
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Relationships between structural stigma, societal stigma, and minority stress among gender minority people by Kristen D. Clark, Mitchell R. Lunn, Jae M. Sevelius, Carol Dawson-Rose, Sandra J. Weiss, Torsten B. Neilands, Micah E. Lubensky, Juno Obedin-Maliver, Annesa Flentje

“…We tested variables identified in the literature as measures of structural stigma inclusive of societal stigma (LGBT + Business Climate Index, state voting behaviors, and Google Trends search data), the most commonly used structural stigma variable (State Policy Environment Tally), and proxy variables (region, population density) for comparison. …”
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Considerations for Establishing a Behavioral Policy-Making and Nudge Institution within the Country's Executive Structure by Seyed Kamal Vaezi, Maryam Darbandi

“…Through this rigorous interview process, a wealth of qualitative data was gathered to assess both the potential and the challenges associated with forming a dedicated behavioral insight institution.ResultsThe literature review summarizes the experiences of countries with behavioral insight teams, presenting them in three areas: operational goals and tasks, institutional and organizational structure, and legal frameworks. …”
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The structure of an amyloid precursor protein/talin complex indicates a mechanical basis of Alzheimer’s disease by Charles Ellis, Natasha L. Ward, Matthew Rice, Neil J. Ball, Pauline Walle, Chloé Najdek, Devrim Kilinc, Jean-Charles Lambert, Julien Chapuis, Benjamin T. Goult

“…Here, we report the crystal structure of an APP/talin1 complex identifying a new way to couple the cytoskeletal machinery to synaptic sites through APP. …”
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Tracing the aggregation pathway of the scaffold protein DISC1: Structural implications for chronic mental illnesses by Abhishek Cukkemane, Nina Becker, Tatsiana Kupreichyk, Henrike Heise, Dieter Willbold, Oliver H. Weiergräber

“…Disrupted in schizophrenia 1 (DISC1) is a pleiotropic scaffold protein that is postulated to comprise large disordered regions and four distinct structured segments with a high proportion of helical or coiled-coil fold. …”
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Development and distribution characteristics of geohazards based on sedimentary-structural evolution in Xide County, southwest Sichuan by Xiaohui XIONG, Yongjian BAI, Yongbo TIE, Yanchao GAO, Hua GE, Wei XU, Lingfeng GONG, Jiazhu WANG, Kai TIAN, Menglong HE, Zhihua ZHU

“…The wide and gentle fold structures in red beds are the disaster-prone environment for landslide. …”
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Comparative Whole-Genome Analysis of Production Traits and Genetic Structure in Baiyu and Chuanzhong Black Goats by Jing Luo, Qi Min, Xueliang Sun, Xinyu Guo, Meijun Song, Xuehui Zeng, Jiazhong Guo, Hongping Zhang, Yanguo Han, Li Li

“…Furthermore, we conducted a comprehensive analysis of genetic diversity, population structure, and selection signatures using whole-genome resequencing data. …”
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Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture by Rajendra A. Morey, Yuanchao Zheng, Henry Bayly, Delin Sun, Melanie E. Garrett, Marianna Gasperi, Adam X. Maihofer, C. Lexi Baird, Katrina L. Grasby, Ashley A. Huggins, Courtney C. Haswell, Paul M. Thompson, Sarah Medland, Daniel E. Gustavson, Matthew S. Panizzon, William S. Kremen, Caroline M. Nievergelt, Allison E. Ashley-Koch, Mark W. Logue

“…Even though we observed model instability in our application of genomic SEM to high-dimensional data, jointly modeling the genetic architecture of complex traits and investigating multivariate genetic links across neuroimaging phenotypes offers new insights into the genetics of cortical structure and relationships to psychopathology.…”
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Presence of Pain Shows Greater Effect than Tendon Structural Alignment During Landing Dynamics by Silvia Ortega-Cebrián, Diogo C. F. Silva, Daniela F. Carneiro, Victor Zárate, Leonel A. T. Alves, Diana C. Guedes, Carlos A. Zárate-Tejero, Aïda Cadellans-Arróniz, António Mesquita Montes

“…This study aims to investigate the relationship between tendon structure, presence of pain, and sex differences in landing kinematics and kinetics during countermovement jumps (CMJ) and tuck jump tests (TJT) in professional volleyball players. …”
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Stress Performance Evaluation of Shield Machine Cutter Head during Cutting Piles under Masonry Structures by Fei Peng, Shiju Ma, Mingyu Li, Kui Fu

“…In the construction of the metro, the development and operation of large-scale underground space in the city cause the construction of metro tunnels near the original underground structures, and the complex environment for passing structures at close range has increased significantly. …”
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Structural placental changes in women with intra-pregnancy novel coronavirus infection COVID-19 (review) by A. V. Yakimova, S. Yu. Borovaya, V. R. Mukhamedshina, N. S. Datsenko, S. G. Kucherenko, I. M. Pozdnyakov, E. V. Nikitenko

“…In those that were excluded from the review, information about the clinical course of pregnancy and its outcome during novel coronavirus infection prevailed, or isolated cases of studying insignificant placental structural changes were discussed. Studies with a small number of observations were selected only in the case of the uniqueness of the published data, the absence of scientific papers where similar studies would have been conducted in larger sample.Results. …”
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Impact of the fishing ban on fish diversity and population structure in the middle reaches of the Yangtze River, China by Juan Du, Juan Du, Huiwu Tian, Zhiyuan Xiang, Kangshun Zhao, Kangshun Zhao, Lixiong Yu, Xinbin Duan, Daqing Chen, Jun Xu, Jun Xu, Mingdian Liu

“…Fish monitoring data collected from 2017–2019 (pre-ban) and 2021–2023 (post-ban) were analyzed to evaluate changes in fish body size, species diversity, and community structure. …”
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TRANSFORMATION OF COASTAL FAUNAL COMPLEX (TETRAPODA) OF THE LYSY LIMAN LAKE IN THE OPERATION OF HYDRAULIC STRUCTURES IN THE MIDDLE COURSE by R. Gubanov, A. Likhovid

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Segmentation of renal structures based on contrast computed tomography scans using a convolutional neural network by I. М. Chernenkiy, M. M. Chernenkiy, D. N. Fiev, E. S. Sirota

“…Develop a neural network to build 3D models of kidney neoplasms and adjacent structures.   Materials and methods. DICOM data (Digital Imaging and Communications in Medicine standard) from 41 patients with kidney neoplasms were used. …”
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The structural and functional brain alternations in tobacco use disorder: a systematic review and meta-analysis by Longyao Ma, Longyao Ma, Qiuying Tao, Qiuying Tao, Jinghan Dang, Jinghan Dang, Jieping Sun, Jieping Sun, Xiaoyu Niu, Xiaoyu Niu, Mengzhe Zhang, Mengzhe Zhang, Yimeng Kang, Yimeng Kang, Weijian Wang, Weijian Wang, Jingliang Cheng, Jingliang Cheng, Yong Zhang, Yong Zhang

“…Consequently, it is important to utilize relevant coordinate data for a comprehensive meta-analysis to identify the shared patterns of structural, functional, and multimodal alternations in TUD.MethodThe present study conducted a systematic retrieval of studies published on PubMed, Web of Science, and Scopus from January 1, 2010, to December 12, 2023, to identify studies on voxel-based morphometry (VBM) and resting-state functional magnetic resonance imaging (rs-fMRI) for TUD. …”
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Petrophysical characteristics of carbonate rocks of organogenic structures of late devonian age (Voronezh horizon) in Orenburg region by A. R. Ryazanov

“…The carbonate rocks represented by organogenic structures of the Voronezh horizon (D3vr) at the Volostnovsky, Vostochno-Volostnovsky and Yuzhno-Volostnovsky fields in the northern part of the East-Orenburg oil and gas bearing region of the Volga-Ural oil and gas bearing province are studied.Aim. …”
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Revealing arginine-cysteine and glycine-cysteine NOS linkages by a systematic re-evaluation of protein structures by Sophia Bazzi, Sharareh Sayyad

“…By systematically analyzing over 86,000 high–resolution X-ray protein structures, we uncovered 69 additional NOS bonds, including arginine-NOS-cysteine and glycine-NOS-cysteine. …”
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