Identification and validation of TUBB, CLTA, and FBXL5 as potential diagnostic markers of postmenopausal osteoporosis by Yue Tan, Yujing Wang, Qin Zhu, Yan Xue, Xuhao Ji, Zhenkun Li, Jiawen Shen, Chengming Sun, Shiqi Ren, Chenlin Zhang, Jianfeng Chen

“…The genetic markers identified in this study hold potential for accurately predicting the risk of PMOP in patients. The findings contribute to understanding the underlying molecular mechanisms of CLTA, TUBB, and FBXL5 in PMOP and may facilitate the development of novel therapeutic strategies and improved monitoring of the disease. …”
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Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics by ChenDeng Lao, Wei Wei, JianWen Cheng, ShiJie Liao, XiaoLin Luo, Qian Huang, HengZhen Huang, JinMin Zhao

“…Three machine learning algorithms identified ATF3, CHKA, CLU, CTNNB1, and FASN as potential biomarkers. …”
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Polypharmacy driven synergistic toxicities in elderly breast cancer chemotherapy drug management and adverse drug reactions: a mini review by Xiran Wang, Xiran Wang, Jin Yang, Jin Yang, Jieying Zhang, Jieying Zhang, Hong Yang, Hong Yang

“…Pharmacist-led reconciliation coupled with algorithmic deprescribing removes ≥1 potentially inappropriate medication in 80% of elders, while electronic rPDDI alerting and DPYD/CYP2D6 genotyping halve severe events without sacrificing efficacy. …”
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Practical Recommendations for Artificial Intelligence and Machine Learning in Antimicrobial Stewardship for Africa by Tafadzwa Dzinamarira, Elliot Mbunge, Claire Steiner, Enos Moyo, Adewale Akinjeji, Kaunda Yamba, Loveday Mwila, Claude Mambo Muvunyi

“…The deployment of AI‐driven solutions presents unprecedented opportunities for optimizing treatment regimens, predicting resistance patterns, and improving clinical workflows. …”
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A Novel Approach for Maize Straw Type Recognition Based on UAV Imagery Integrating Height, Shape, and Spectral Information by Xin Liu, Huili Gong, Lin Guo, Xiaohe Gu, Jingping Zhou

“…Accurately determining the distribution and quantity of maize straw types is of great significance for evaluating the effectiveness of conservation tillage, precisely estimating straw resources, and predicting the risk of straw burning. The widespread adoption of conservation tillage technology has greatly increased the diversity and complexity of maize straw coverage in fields after harvest. …”
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Feasibility and case studies on converting small hydropower stations to pumped storage by Yangqing Dan, Qingyue Chen, Daren Li, Wenhuan Bai, Weiming Zhou, Anyu Yang, Jia Yang

“…The proposed conversion scheme has been assessed, and predictions regarding annual operating hours, power generation, and energy consumption have been formulated. …”
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Investigation of granuloma-targeted host-pathogen interactions identify vaccine correlates of immune protection associated with control of M. tuberculosis replication by David Forrest Ackart, Dr. Faye Lanni, Victoria Mitcham, Dr. G. Brooke Anderson, Dr. Michael Lyons, Dr. Marcela Henao-Tamayo, Dr Brendan Podell

“…While a number of blood transcriptomic signatures have been shown to predict clinical states of TB in human subjects, no correlates exist to indicate immune signatures that control bacterial growth, which would inform improved vaccine design. …”
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Novel estrogen-related gene variants identified by whole-exome sequencing in pregnancy-associated intrahepatic cholestasis by Hua Lai, Siming Xin, Jinliang Zhang, Yang Hu, Wenjuan Fan, Hong Wan, Bowen Chen, Yang Zou, Xiaoming Zeng, Xianxian Liu

“…These variants exhibited the following characteristics: (1) complete absence in 1,237 controls and all public genomic databases (1000 Genomes, ExAC, and dbSNP); (2) evolutionary conservation of the affected residues, with unanimous pathogenic predictions from all algorithms (PolyPhen-2: damaging; SIFT: deleterious; MutationTaster: disease-causing); (3) molecular modeling demonstrating structural perturbations in critical functional domains, including steroid-binding and redox partner interaction sites. …”
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Federated Learning Based on an Internet of Medical Things Framework for a Secure Brain Tumor Diagnostic System: A Capsule Networks Application by Roman Rodriguez-Aguilar, Jose-Antonio Marmolejo-Saucedo, Utku Köse

“…The precision rate indicates that the CapsNet model performs well in accurately predicting true classes. Additionally, the recall findings suggest that this model is effective in detecting the target classes of meningiomas, pituitary tumors, and gliomas. …”
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Exploration of Biomarkers of Psoriasis through Combined Multiomics Analysis by Lu Xing, Tao Wu, Li Yu, Nian Zhou, Zhao Zhang, Yunjing Pu, Jinnan Wu, Hong Shu

“…The druggable genes were predicted using DGIdb. Finally, the expressions of hub genes in psoriasis lesions and healthy controls were detected by immunohistochemistry (IHC) and quantitative real-time PCR (RT-qPCR). …”
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Machine learning−derived multivariable predictors of postcardiotomy cardiogenic shock in high-risk cardiac surgery patientsCentral MessagePerspective by Edward G. Soltesz, MD, MPH, Randi J. Parks, PhD, Elise M. Jortberg, MS, Eugene H. Blackstone, MD

“…Objective: To develop a model for preoperatively predicting postcardiotomy cardiogenic shock (PCCS) in patients with poor left ventricular (LV) function undergoing cardiac surgery. …”
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Supervised machine learning and genotype by trait biplot as promising approaches for selection of phytochemically enriched Rhus coriaria genotypes by Hamid Hatami Maleki, Reza Darvishzadeh, Ahmad Alijanpour, Yousef Seyfari

“…By using 13 feature selection algorithms, ISSR loci (U823) L1, (U835) L1, (U801) L1, (U816) L2, (U816) L4, (U835) L4, (U854) L1, and (U835) L9 were identified as functional markers which could predict phytochemical response of sumac germplasm. …”
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Machine learning unveils key Redox signatures for enhanced breast Cancer therapy by Tao Wang, Shu Wang, Zhuolin Li, Jie Xie, Kuiying Du, Jing Hou

“…Our results demonstrate that AIARS significantly outperforms existing prognostic models in predicting breast cancer outcomes, offering a robust tool for personalized treatment planning. …”
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Assessing current and future areas of ecological suitability for Lutzomyia shannoni in North America by Sydney DeWinter, Grace K. Nichol, Christopher Fernandez-Prada, Amy L. Greer, J. Scott Weese, Katie M. Clow

“…The objectives of this study were to predict the current and future ecological suitability of regions across North America for Lu. shannoni and to identify variables driving ecological suitability. …”
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Improved YOLOv8 Model for Phenotype Detection of Horticultural Seedling Growth Based on Digital Cousin by Yuhao Song, Lin Yang, Shuo Li, Xin Yang, Chi Ma, Yuan Huang, Aamir Hussain

“…Crop phenotype detection is a precise way to understand and predict the growth of horticultural seedlings in the smart agriculture era to increase the cost-effectiveness and energy efficiency of agricultural production. …”
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Design of a Conveyer Trough Bolt Signal Acquisition System and Bayesian Ensemble Identification Method for Working State by Yi Lian, Bangzhui Wang, Meiyan Sun, Kexin Que, Sijia Xu, Zhong Tang, Zhilong Huang

“…Addressing the challenge of predicting the state of the combine harvester’s conveyor trough bolted structure prior to vibration-induced failure, this study addresses this by investigating signal analysis, system design, and condition identification for these critical components. …”
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Non-invasive liver fibrosis markers are increased in obese individuals with non-alcoholic fatty liver disease and the metabolic syndrome by Anders Askeland, Rikke Wehner Rasmussen, Mimoza Gjela, Jens Brøndum Frøkjær, Kurt Højlund, Maiken Mellergaard, Aase Handberg

“…We used MRI (T1 relaxation times (T1) and liver stiffness), circulating biomarkers (CK18, PIIINP, and TIMP1), and algorithms (FIB-4 index, Forns score, FNI, and MACK3 score) to assess their potential in predicting liver fibrosis risk. …”
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Identification of M1 macrophage infiltration-related genes for immunotherapy in Her2-positive breast cancer based on bioinformatics analysis and machine learning by Sizhang Wang, Xiaoyan Wang, Jing Xia, Qiang Mu

“…Then, four overlapping M1 macrophage infiltration-related genes (M1 MIRGs), namely CCDC69, PPP1R16B, IL21R, and FOXP3, were obtained using five machine-learning algorithms. Subsequently, nomogram models were constructed to predict the incidence of Her2-positive breast cancer patients. …”
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Oxidative balance is associated with diabetic kidney disease and mortality in adults with diabetes mellitus: Insights from NHANES database and Mendelian randomization by Li Jiang, Jie Jian, Xulin Sai, Hongda Yu, Wanxian Liang, Xiai Wu

“…The physical activity was identified as the core variable predicting DKD risk by two machine learning algorithms. …”
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A Reproducible Method for Donor Site Computed Tomography Measurements in Abdominally Based Autologous Breast Reconstruction by Damini Tandon, MD, Arthur Sletten, MD, PhD, Austin Ha, MD, Gary B. Skolnick, BA, MBA, Paul Commean, BEE, Terence Myckatyn, MD

“…Larger patient cohorts must be leveraged to determine correlations between abdominal CT scan findings and donor site outcomes using machine learning algorithms that generate models for predicting abdominal donor site complications.…”
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