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21421
ASSOCIATION BETWEEN ADENOID HYPERTROPHY AND CHRONIC RHINOSINUSITIS IN CHILDREN: A SYSTEMATIC REVIEW
Published 2025-05-01“…Elevated levels of pro-inflammatory mediators (TGF-β1, sIL-2R, MMP-2, MMP-9, TIMP-1) and decreased levels of protective factors (IgA, BLIMP-1, SP-D) were reported. …”
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21422
Dietary Tea Polyphenols Improve Growth Performance and Intestinal Microbiota Under Chronic Crowding Stress in Hybrid Crucian Carp
Published 2025-07-01“…This study systematically investigated the effects of dietary tea polyphenols (TPs, major bioactive polyphenols from <i>Camellia sinensis</i> with potent antioxidant and anti-inflammatory properties) on the growth performance and intestinal health of hybrid crucian carp HCC2 under chronic crowding stress. …”
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21423
Toward the DNA methylation haplotype map of 11 common solid cancers
Published 2025-09-01“…Inter-tumor heterogeneity links MHB discordance to driver mutations and inflammatory pathways. Finally, we demonstrate that MHBs serve as effective biomarkers for cancer detection, performing competitively to existing methods. …”
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21424
STIM1‐mediated calcium influx controls antifungal immunity and the metabolic function of non‐pathogenic Th17 cells
Published 2020-07-01“…Our study further revealed distinct roles of STIM1 in regulating transcription and metabolic programs in non‐pathogenic Th17 cells compared to pathogenic, proinflammatory Th17 cells, a finding that may potentially be exploited for the treatment of Th17 cell‐mediated inflammatory diseases.…”
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21425
Catastrophic antiphospholipid COVID-19 syndrome
Published 2021-03-01“…The course of the disease was monitored using other routine clinical (temperature, complete blood and urine counts) tests and blood panel tests reflecting the severity of the systemic inflammatory response (ferritin, CRP, interleukins 6 and 18), and the state of the hemostatic, respiratory, circulatory, liver and kidney systems.Results. …”
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21426
Polymer-free β-cyclodextrins and mefenamic acid inclusion complex nanofibers for enhanced drug solubility and biomedical applications
Published 2025-08-01“…MFA, a non-steroidal anti-inflammatory drug (NSAID), has low water solubility, but its solubility increases when complexed with CDs. …”
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21427
Cyclosporine combined with eltrombopag for treatment of secondary graft failure after autologous hematopoietic stem cell transplantation
Published 2024-09-01“…According to PET/CT data 36 months after auto-HSCT, the patient had a local increase in the level of 18F-fluorodeoxyglucose fixation (maximum standardized uptake value 3.33), possibly of an inflammatory nature, in the body of the L4 vertebra on the background of bone cement after vertebroplasty performed at the onset of the disease. …”
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21428
Case Report: Rare multisystem metastasis in head and neck paraganglioma with SDHB pathogenic variant and KIF1B VUS manifested as FUO
Published 2025-08-01“…Laboratory examinations showed elevated inflammatory markers (CRP, ESR, IL-6, and Ferritin) but no abnormalities in infection, immune, or tumor markers. …”
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21429
High-risk sexual behavior and HIV/STDs cascade of care in migrants: results from an Italian dedicated outpatient clinic
Published 2021-03-01“…Four (16%) people had latent syphilis; in 12 (48%) people, HPV-related genital warts were present, 7 (28%) people had Molluscum contagiosum, and 6 (24%) women had pelvic inflammatory diseases. Among patients referring no symptoms, there were 10 (41.7%) HBsAg positivities, one (4.2%) HIV infection, four (16.7%) latent syphilis, one (4.2%) HPV-related genital infection, and one (4.2%) PID. …”
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21430
Lipoprotein(a) and Blood Monocytes as Factors for Progression of Carotid Atherosclerosis in Patients with Premature Coronary Heart Disease
Published 2025-06-01“…Monocytes in individuals with an elevated Lp(a) level are represented by an activated inflammatory phenotype and have an increased ability for transendothelial migration. …”
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21431
Lymph node recurrence and re-excision after primary tumor resection of a histiocytic sarcoma of duodenal origin: a case report
Published 2022-10-01“…The biopsy showed erosions of the mucosal epithelium and inflammatory cell infiltration, but no evidence of malignancy. …”
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21432
The first experience of two-stage treatment of transsphincteric fistulas of rectum by means of fibrin sealant
Published 2018-08-01“…Treatment results of the patient group that matched inclusion criteria were analyzed: straight fistulous tract, absence of inflammatory changes and severe fibrosis in the area of fistula internal orifice. …”
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21433
Inhibition of astrocyte signaling leads to sex-specific changes in microglia phenotypes in a diet-based model of cerebral small vessel disease
Published 2025-08-01“…Here, we assessed the impact of astrocytic signaling on microglia, which set the inflammatory tone in brain. Seven-to-eight-week-old male and female C57BL/6 J mice received intrahippocampal injections of adeno-associated virus (AAV) expressing EGFP (AAV2/5-Gfa2-EGFP) or AAV expressing the NFAT inhibitor VIVIT (i.e., AAV2/5-Gfa2-VIVIT-EGFP). …”
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21434
Changes in olfactory function and serum interleukin-6 levels in the acute phase of bipolar I disorder: a longitudinal study
Published 2025-07-01“…There is a potential correlation between inflammatory activity and olfactory dysfunction in manic BD patients, but its causal relationship and specific mechanism need to be further verified.…”
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21435
Predicted skeletal muscle index as a scalable marker for sarcopenia risk and mortality in older Chinese adults
Published 2025-08-01“…Logistic regression assessed pSMI’s association with sarcopenia, and Cox models evaluated mortality risk, adjusting for demographics, behaviors, comorbidities, and inflammatory markers.ResultsSarcopenia prevalence decreased from 55 to 67% in the lowest pSMI quartile (Q1) to 0.4% in the highest (Q4). …”
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21436
Anesthesiologic Provision of Osteosynthesis of the Neck of the Femur in Geriatric Patients
Published 2005-08-01“…All Group 1 patients operated on under spinal anesthesia experienced postoperative pain whose relief required the use of nonsteroidal anti-inflammatory drugs (ketorol, ketonal, baralgin) and opioids (promedole, omnopon), 44% of cases requiring multiple administration of narcotic analgesics within the first and second postoperative days. …”
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21437
IgM- and IgA-response of peritoneal B-1 cells to the TI-2 antigen with the presence of γδT cells in vitro
Published 2021-05-01“…It limits penetration of pathogens into the bloodstream. Inflammatory diseases such as Crohn disease and colitis may be associated with disorders of IgA synthesis. …”
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21438
Tangeretin Improves the Memory of Swiss Mice, Suggesting Potential Molecular Interventions Through Animal Behavior Assessments and In Silico Studies
Published 2025-05-01“…ABSTRACT Introduction Tangeretin (TAN), a polymethoxylated flavone from citrus peels, exhibits neuroprotective, anti‐inflammatory, and antioxidant properties. This study aims to evaluate the memory‐enhancing effects of TAN in Swiss mice and explore its potential molecular interactions with the D2 dopamine (DOP) receptor through in vivo behavioral assessments and in silico approaches. …”
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21439
Nutrients and phytochemicals characterisations, acute and sub-acute oral toxicity studies of BobyGuard C, a polyherbal nutraceutical with anti-breast cancer properties
Published 2025-05-01“…BobyGuard C (BGC) is a novel polyherbal nutraceutical formulated from five plants, selected for their antioxidant, anticancer, anti-inflammatory and nutritional properties to be used for breast cancer management. …”
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21440
Effects of mesenchymal stromal cells on monocyte differentiation to M1 phenotype and M1/M2 macrophage switching
Published 2018-03-01“…In addition, MSCs did not influence the expression of CD206, as well as the production of pro- (IL-1β, TNF-α, IL-6, IL-12) and anti-inflammatory (IL1-ra, IL-4, IL-10) cytokines, immunoregulatory cytokines (IFN-γ, IL-17) and chemokines (IP-10, MCP-1, MIP-1b, Rantes, Eotaxin).Conclusions: The ability of MSC to induce the M2 phenotype depends on the stage of differentiation of monocyte/macrophages. …”
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