Applications of mutagenesis methods on affinity maturation of antibodies in vitro by LIU Yuan, LIN Manman, ZHANG Xiao, XU Chongxin, JIAO Linxia, ZHONG Jianfeng, WU Aihua, LIU Xianjin

“…In chain shuffling, a variable heavy or light chain of a specific antibody is recombined with a complementary variable domain library. …”
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Modeling Wetland Biomass and Aboveground Carbon: Influence of Plot Size and Data Treatment Using Remote Sensing and Random Forest by Tássia Fraga Belloli, Diniz Carvalho de Arruda, Laurindo Antonio Guasselli, Christhian Santana Cunha, Carina Cristiane Korb

“…Remote sensing (RS) data effectively estimate and map AGB and Corg in wetlands using various techniques, but there is still room to improve the efficiency of machine learning (ML)-based approaches. …”
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Modeling of project activities for UAV modernization to conduct swarm drone attack missions by Oleg Fedorovych, Leonid Malieiev, Oleksii Hubka, Andrei Popov

“…The models are intended to optimize new functions related to control, coordination, and navigation, enabling UAVs to perform as part of drone swarms in military missions. …”
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Optimal selection of satellite XCO₂ images for urban CO₂ emission monitoring by A. Danjou, G. Broquet, A. Schuh, F.-M. Bréon, T. Lauvaux, T. Lauvaux

“…This study analyzes the performances of an automated method for estimating urban emissions as a function of the targeted cities and of the atmospheric conditions. …”
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Human saliva exerts strong type-dependent effects on adenovirus infectivity by Erwan Sallard, Wenli Zhang, Nikita Chilakamarri, Setareh Farzanehkari, Setareh Farzanehkari, Inga Marte Charlott Seuthe, Anja Ehrhardt, Malik Aydin, Malik Aydin

“…All human Ads used were replication-competent and expressed a GLN cassette containing a green-fluorescent protein, nano-luciferase, and neomycin resistance. Loss-of-function experiments were conducted by immunoprecipitation or enzymatic digestion of specific saliva components to decipher related mechanisms.ResultsTemporal and inter-individual variability in saliva samples were observed, validating the use of a saliva pool to represent the population. …”
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The Role of the Gut Microbiome in Exercise-Induced Inflammation and Recovery: A Narrative Review by Stanisław Dudek, Weronika Koziak, Aleksandra Bętkowska, Agata Kornacka, Kamila Szostak, Rafał Tomaka, Michalina Makieła, Wojciech Dudek, Anna Byra

“…While moderate exercise enhances immune function and microbial diversity, excessive training can lead to gut dysbiosis, increased intestinal permeability, and chronic inflammation. …”
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Complementing Dynamical Downscaling With Super‐Resolution Convolutional Neural Networks by Deeksha Rastogi, Haoran Niu, Linsey Passarella, Salil Mahajan, Shih‐Chieh Kao, Pouya Vahmani, Andrew D. Jones

“…Modifications, such as incorporating elevation data and data pre‐processing enhances overall model performance, while using exponential and quantile loss functions improve the simulation of extremes. Our findings show SRCNN models efficiently and skillfully downscale precipitation from GCMs. …”
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Predicting the Permeability of Pervious Concrete Based on the Beetle Antennae Search Algorithm and Random Forest Model by Jiandong Huang, Tianhong Duan, Yi Zhang, Jiandong Liu, Jia Zhang, Yawei Lei

“…The results showed that the hyperparameters of RF can be tuned by the BAS efficiently; the BAS can combine the conventional RF algorithm to construct the evolved model to predict the permeability of pervious concrete; the cement/aggregate ratio was the most significant variable to determine the permeability, followed by the coarse aggregate proportions.…”
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Simulation of wheat yield by nitrogen and nonlinearity of environmental conditions by Ana P. B. Trautmann, José A. G. da Silva, Manuel O. Binelo, Antonio C. Valdiero, Luana Henrichsen, Natiane C. F. Basso

“…The experimental design was a randomized block design with four repetitions in a 4 x 3 factorial scheme for N-fertilizer doses (0, 30, 60, 120 kg ha-1) and nutrient supply forms [100% in phenological stage V3 (third expanded leaf); (70%/30%) in the phenological stage V3/V6 (third and sixth expanded leaf) and; fractionated (70%/30%) at the phenological stage V3/E (third expanded leaf and beginning of grain filling)], respectively, in the soybean/wheat and corn/wheat systems. The pertinence functions and the linguistic values established for the input and output variables are adequate for the use of fuzzy logic. …”
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A Multi-objective Transmission Expansion Planning Strategy: A Bilevel Programming Method by S. Zolfaghari-Moghaddam, T. Akbari

“…This paper describes a methodology for transmission expansion planning (TEP) within a deregulated electricity market. Two objective functions including investment cost (IC) and congestion cost (CC) are considered. …”
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Modeling Spatial Data with Heteroscedasticity Using PLVCSAR Model: A Bayesian Quantile Regression Approach by Rongshang Chen, Zhiyong Chen

“…Through an approximation of the nonparametric functions with free-knot splines, we develop a Bayesian sampling approach that can be applied by the Markov chain Monte Carlo (MCMC) approach and design an efficient Metropolis–Hastings within the Gibbs sampling algorithm to explore the joint posterior distributions. …”
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Bankruptcy rules and sustainable water management: A MODSIM-NSGAII simulation multi-objective optimization framework for equitable transboundary water allocation by Bentolhoda Asl-Rousta, S. Jamshid Mousavi

“…This study addresses these challenges by introducing a new optimal bankruptcy rule (OpPro rule) through a simulation-optimization model (MODSIM-NSGAII), where MODSIM simulates the spatial and temporal variability of water resources, and the NSGA-II optimization algorithm includes two objective functions of maximizing basin-wide ecological sustainability and maximizing economic efficiency reflecting ''equitable and reasonable utilization'' of water. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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Early Predictive Value of the Glucose‐to‐Lymphocyte Ratio for the Occurrence of Stroke‐Associated Pneumonia by Fuqiang Zhou, Liju Ma, Min Li, Haijiang Li, Heying Yang, Ye Xu, Kuankuan Dang, Fengchen Gao, Haimei Sun

“…The GLR was converted into a categorical variable for trend testing, and compared the predictive efficiency of GLR through the receiver operating characteristic (ROC) curve and Bonferroni correction analysis. …”
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Supply chain management and optimization in transportation logistics by Saoussen Krichen

“…SCM can also be seen as the process of optimizing a set of decisions that generate cost-effective solutions which provide efficient plans for acting on numerous levels while considering all decision-making standpoints. …”
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Penerapan Importance Performance Analysis (IPA) pada Evaluasi Keberlanjutan Penggunaan e-filing untuk Pelaporan Pajak Perorangan by Imelda Saluza, Dewi Sartika

“…Beberapa indikator tersebut antara lain adalah Understandability (kejelasan informasi yang diberikan oleh e-filing), Contact (kontak yang dapat dihubungi), Functionality (peningkatan kualitas dan mutu pajak), Ease of Use (e-filing sulit dipelajari), Usefulness (penghematan waktu pelaporan), Service Quality, Efficiency (pengaksesan e-filing dengan gadget lain), Fulfillment (kesulitan dalam memenuhi kebutuhan pelapor). …”
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Design of an Automatic Defect Identification Method Based ECPT for Pneumatic Pressure Equipment by Bo Zhang, YuHua Cheng, Chun Yin, Xuegang Huang, Sara Dadras, Hadi Malek

“…The presented feature extraction algorithm contains four elements: data block selection; variable step search; relation value classification; and between-class distance decision function. …”
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Exploring user usability perceptions and acceptance of chording-enabled keyboards: A perspective between human-computer interaction by Jeryllou Kay O. San Pedro, Ardvin Kester S. Ong, Sean Dominic O. Mendoza, Jann Ryan J. Novela, Ma. Janice J. Gumasing

“…The objective of this study was to determine the variables affecting the acceptance and perceptions of people towards chording-enabled keyboards. …”
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Grid-connected PV inverter system control optimization using Grey Wolf optimized PID controller by Monika Gupta, P. M. Tiwari, R. K. Viral, Ashish Shrivastava, Basem Abu Zneid, Iryna Hunko

“…Conventional controllers such as P and PI are widely used in PV applications due to their simplicity, but they exhibit notable limitations in dynamic environments, including increased Total Harmonic Distortion (THD), slower transient response, and poor voltage regulation—particularly under variable irradiance conditions. The proposed GWO-PID method overcomes these limitations by leveraging the GWO algorithm’s global search capability to dynamically optimize the PID gains (Kp, Ki, Kd) based on a composite fitness function that minimizes Mean Squared Error (MSE) and THD. …”
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COBRAme: A computational framework for genome-scale models of metabolism and gene expression. by Colton J Lloyd, Ali Ebrahim, Laurence Yang, Zachary A King, Edward Catoiu, Edward J O'Brien, Joanne K Liu, Bernhard O Palsson

“…This reformulated model gives functionally identical solutions to previous E. coli ME-models while using 1/6 the number of free variables and solving in less than 10 minutes, a marked improvement over the 6 hour solve time of previous ME-model formulations. …”
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