Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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SMART Based Multi-Point Matching Assisted Approximation of Renewable Interconnected Power System by Umesh Kumar Yadav, V. P. Singh, Luigi Fortuna, Umesh Kumar Sahu

“…For the error minimization, objective function is framed. The objective function is then converted in the form of weighted objective function by employing SMART based weight determination approach. …”
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Analysis of Surface Roughness and Machine Learning-Based Modeling in Dry Turning of Super Duplex Stainless Steel Using Textured Tools by Shailendra Pawanr, Kapil Gupta

“…One of the most critical aspects of turning, and machining in general, is the surface roughness of the finished product, which directly influences the performance, functionality, and longevity of machined components. …”
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Evaluation of the efficacy of hydrated sodium calcium aluminosilicate at mitigating the negative impact of aflatoxicosis on nutrient digestibility and other production- and health-... by Ahmed Ali Saleh, Rashed A. Alhotan, Mohammed A.A. Al-Badwi, Elsayed Osman Hussein, Livio Galosi, Giuseppe Crescenzo, Mahmoud Alagawany, Walied Abdo, Sara Mahmoud Omar, Claudia Zizzadoro

“…Importantly, not all types of aluminosilicates have the same decontaminating efficiency; thus, a full characterization of the protective properties of each single material would assist in selecting the most appropriate binder. …”
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Modeling of Thermal Distributions around a Barrier at the Interface of Coating and Substrate by Ali Sahin

“…Using integral transform method, two-dimensional steady-state diffusion equation with variable conductivity is turned into constant coefficient differential equation. …”
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AngleCam: Predicting the temporal variation of leaf angle distributions from image series with deep learning by Teja Kattenborn, Ronny Richter, Claudia Guimarães‐Steinicke, Hannes Feilhauer, Christian Wirth

“…The plausibility of the predicted leaf angle time series was underlined by its close relationship with environmental variables related to transpiration. The evaluations confirm that AngleCam is a robust and efficient method to track leaf angles under field conditions. …”
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Calibration of Low-Cost Capacitive Soil Moisture Sensors for Irrigation Management Applications by Ahmed A. Abdelmoneim, Christa M. Al Kalaany, Roula Khadra, Bilal Derardja, Giovanna Dragonetti

“…The results showed that with higher soil moisture contents (above 30%), the sensor-to-sensor variability becomes significant, with a coefficient of variation (CV) ranging between 10 and 16%; meanwhile, in lower soil moisture contents, the CV ranged between 6.5 and 10.3%, implying that it is more consistent in lower moisture content within this soil condition. …”
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Correlation between Stressful Life Events and Suicidal Ideation among Patients with Schizophrenia in Remission Stage: A Cross-sectional Study by Ashok Silamban, Kailash Sureshkumar, Aravindh Manogaran, Shabeeba Z Kailash

“…Introduction: Patients with schizophrenia often exhibit impaired executive brain function, which disrupts their daily activities. Relapse in schizophrenia has been linked to stressful life events. …”
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A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery by Justin E. Kung, Chase Gauthier, Yianni Bakaes, Michael Spitnale, Richard A. Bidwell, David G. Edelman, Heidi C. Ventresca, J. Benjamin Jackson, Shari Cui, Gregory Grabowski

“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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Temporal disorientation during war: associations with work-family conflict, emotional distress, and burnout by Irene Diamant, Maor Kalfon Hakhmigari

“…Principal Component Analysis (PCA) was used to validate the factor structure of the Hebrew version of Temporal Disorientation questionnaire, Pearson correlation coefficient was used to evaluated correlations among the study variables; Hierarchical linear regression was used to model the outcome variables, emotional distress and burnout.ResultsTemporal confusion and difficulties in future orientation during wartime were significantly associated with emotional distress. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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A United Probabilistic Approach to Minimising the Sum of Absolute Values by Changyong Feng, Honghong Liu, Ethan Poon, Ge Feng

“…Methodology: The sum of absolute values can be standardized so that the sum of the coefficients equals 1. In this case, the sum of absolute values takes the form 𝐸𝐸|𝑋𝑋−𝑎𝑎|, where 𝑋𝑋 is a random variable. …”
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‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’ by Natale Massimino Ucin, Manassé Nimpagaritse, Shital Mahindra Maru, Mulatedzi Makhado, Shiferaw Mitiku Tebeka

“…Abstract Background of the study Along with developments in the clinical domain, medical equipment is becoming more sophisticated, and it needs to function at peak efficiency. In this case, hospitals should priorities the prompt and effective maintenance of life-saving equipment. …”
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Effect of Central Motor and Neuromuscular Impairments on Front Crawl Body Roll Characteristics of Para Swimmers by Yu-Hsien Lee, Dawn Nicola O’Dowd, Luke Hogarth, Brendan Burkett, Carl Payton

“…CMNI swimmers were divided into three upper-limb [mild (n = 9), moderate (n = 9), severe (n = 9)] and three lower-limb function subgroups [bilateral (n = 2), unilateral (n = 6), without kick (n = 19)] based on their Froude efficiency (a measure of how effectively upper limbs contribute to propulsion) and the number of lower limbs actively kicking during trials, respectively. …”
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The role of housing price mediation in transferring the effect of heterogeneous behavior of investors in the housing sector on Iran's economic growth by Aliakbar Gholizadeh, Shahla Samadipour

“…The housing price is also a variable of economic growth function transfer with a threshold equal to 0.0266 percent The estimated coefficients of the first and second regimes indicate the asymmetric behavior of investors on housing prices. …”
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Immunological Avalanches in Renal Immune Diseases by Davide Viggiano, Pietro Iulianiello, Antonio Mancini, Candida Iacuzzo, Luca Apicella, Renata Angela Di Pietro, Sarah Hamzeh, Giovanna Cacciola, Eugenio Lippiello, Andrea Gigliotti, Carmine Secondulfo, Giancarlo Bilancio, Giuseppe Gigliotti

“…Additionally, biological age calculations provide valuable prognostic information, while proteinuria measurements offer efficient sampling for system dynamics assessment. …”
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Vitamin D Levels in Pre-frail Older Adults and Its Correlation with Hand Grip Strength by Noto Dwimartutie, Siti Setiati, Tirza Z Tamin, Ani Retno Prijanti, Alida R Harahap, Dyah Purnamasari, Kuntjoro Harimurti, I Dewa Putu Pramantara

“…After adjusting for age, comorbidities, nutritional status, functional status, BMI, protein intake, and sun exposure score, regression analysis between hand grip strength and vitamin D levels gave standard coefficient beta = 0.255 (P = 0.013). …”
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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…During this time, the number of changes in the target variables by the variables themselves decreases and the changes in the variables caused by the shock of the exchange rate channel increase. …”
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Changes in life satisfaction over six years in the general population: A longitudinal study with the Satisfaction With Life Scale (SWLS). by Andreas Hinz, Anja Mehnert-Theuerkauf, Heide Glaesmer, Matthias L Schroeter, Ana N Tibubos, Katja Petrowski, Michael Friedrich

“…However, the knowledge about long-term changes in life satisfaction and the associations between such changes and changes in other variables of physical and mental health is limited.…”
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