Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Pericellular proteolysis is a key mechanism mediating the aforementioned processes.AimThis study primarily aimed to define mechanistic pathways of plasmin formation and its consequences on MSC phenotype and functioning. We have also investigated the regulatory mechanisms mediated by PAI-1 and the ability of MSCs to shed microvesicles bearing the proteolytic machinery.MethodsHuman MSCs were derived from bone marrow or umbilical cord donors. …”
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Some New Connection Relations Related to Classical Orthogonal Polynomials by Wathek Chammam, Wasim Ul-Haq

“…In this paper, we deal with a problem of positivity of linear functionals in the linear space ℙ of polynomials in one variable with complex coefficients. …”
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Novel Approximations to the Damped Parametric Driven Pendulum Oscillators by Weaam Alhejaili, Alvaro H. Salas, S. A. El-Tantawy

“…For analyzing and solving the current pendulum equation, we reduce this equation to the damped Duffing equation (DDE) with variable coefficients. After that, the DDE with variable coefficients is divided into two cases. …”
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Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

“…The nanocomplex accumulated efficiently and uniformly across all CRC cell lines, regardless of their aggressiveness or drug sensitivity. …”
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Neutralizing monoclonal antibodies protect against human adenovirus type 55 infection in transgenic mice and tree shrews by Xinglong Liu, Zhengfeng Li, Xiao Li, Xiaoyan Zhang, Yali Zheng, Wan Su, Ying Feng, Yutong Liu, Weixuan Wu, Xikui Sun, Nana Wang, Xianmiao Ye, Zhichao Zhou, Wenkuan Liu, Jun He, Wei Wang, Linbing Qu, Rong Zhou, Ling Chen, Liqiang Feng

“…These mAbs recognized the hyper-variable-region (HVR) 1, 2, or 7 of viral hexon protein, or the fibre knob. …”
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Approximate analytical solution of a class of highly nonlinear time–fractional-order partial differential equations by Richard Olu Awonusika

“…The method assumes a fractional power series in the time variable whose expansion coefficients are functions of the space variable. …”
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Spatial Differentiation and Correlation of Ecological Stoichiometric Characteristics of Cynodon dactylon and Soil in the Water-level Fluctuation Zone of the Three Gorges Reservoir... by XU Liwen, ZHANG Yuewei, JIAN Chen, ZHANG Yuanyuan, WANG Xiaofeng

“…However, the variability in C/N and C/P ratios in roots and stems were slightly stronger than that in leaves, suggesting that C. dactylon has evolved a strategy for maintaining stable physiological functions in leaves. 4) There were significant correlations of the nutrient contents between C. dactylon and soil, with the nitrogen supply of soil being the key factor influencing the variation of nutrient contents in C. dactylon. …”
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Homogenization in Sobolev Spaces with Nonstandard Growth: Brief Review of Methods and Applications by Brahim Amaziane, Leonid Pankratov

“…We review recent results on the homogenization in Sobolev spaces with variable exponents. In particular, we are dealing with the Γ-convergence of variational functionals with rapidly oscillating coefficients, the homogenization of the Dirichlet and Neumann variational problems in strongly perforated domains, as well as double porosity type problems. …”
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Hierarchical GraphCut Phase Unwrapping Based on Invariance of Diffeomorphisms Framework by Xiang Gao, Xinmu Wang, Zhou Zhao, Junqi Huang, Xianfeng David Gu

“…However, the presence of noise, occlusions, and piecewise continuous phase functions induced by complex 3D surface geometry makes the inverse reconstruction of the true phase extremely challenging. …”
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Positive Invertibility of Matrices and Exponential Stability of Linear Stochastic Systems with Delay by Ramazan Kadiev, Arcady Ponosov

“…The work addresses the exponential moment stability of solutions of large systems of linear differential Itô equations with variable delays by means of a modified regularization method, which can be viewed as an alternative to the technique based on Lyapunov or Lyapunov-like functionals. …”
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ANALYTICAL SOLUTIONS OF NON-LINEAR HEAT CONDUCTION PROBLEMS by V. A. Bondarev

“…An example of calculations in the case of variable coefficients of thermal conductivity and radiative heating transfer on the boundaries is considered in the paper. …”
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Gevrey Asymptotics for Logarithmic-Type Solutions to Singularly Perturbed Problems with Nonlocal Nonlinearities by Stéphane Malek

“…Their coefficients and forcing terms comprise polynomial and logarithmic-type functions in time and are bounded holomorphic in space. …”
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CHANGES AND TRENDS IN WINE PRODUCTION AND CONSUMPTION IN THE WORLD AND ROMANIA DURING THE PERIOD 2007-2018 by Agatha POPESCU

“…The paper analyzed the evolution of wine production and consumption in Romania and at the world level in order to identify the main changes and trends in the period 2007-2018 using official data which have been processed using fixed and variable indices, correlation coefficients, regression functions, consumption/production rate, export/consumption rate, self sufficiency rate and import dependency rate. …”
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Effect of electrostatic and intermolecular forces on free small vibrations of a micro-cantilever by Геннадий Иванович Михасев, Вячеслав Владимирович Мисник, Марина Георгиевна Ботогова

“…The derived governing equation with variable coefficients is solved using both the asymptotic approach and the Runge – Kutta method. …”
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Dynamic Stability of a Circular Pre-Stressed Elastic Orthotropic Plate Subjected to Shock Excitation by Yuriy A. Rossikhin, Marina V. Shitikova

“…Behind the fronts of these waves, the solution is constructed in terms of ray series, which coefficients are the different order discontinuities in partial time-derivatives of the desired functions, and a variable is the time elapsed after the wave arrival at the plate’s point under consideration. …”
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Dynamics of a Nonlinear Energy Harvesting System in Time-Delayed Feedback Control under Stochastic Excitations by Shuling Zhang, Ying Zhang, Zhongkui Sun, Xiaxia Duan

“…An equivalent decoupling system can be obtained by using a variable transformation. Based on the standard stochastic averaging method, the Fokker–Plank–Kolmogorov equation and the stationary probability density functions of the amplitude, displacement, and velocity of the harvester are obtained, respectively. …”
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Faktor-Faktor yang Mempengaruhi Auditor Switching dengan Financial Distress sebagai Pemoderasi by Herninda Pitaloka, Agung Guritno

“…The analysis included descriptive statistical tests, model feasibility tests, classification matrix tests, the formation of logistic regression functions, partial parameter significance tests, simultaneous parameter significance tests, coefficients of determination tests and MRA tests. …”
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Monte Carlo-Based Strategy for Assessing the Impact of EEG Data Uncertainty on Confidence in Convolutional Neural Network Classification by Pierre Sedi Nzakuna, Vincenzo Gallo, Vincenzo Paciello, Aime Lay-Ekuakille, Angelo Kuti Lusala

“…We introduce robust evaluation metrics, including the proportion of area under the curve (AUC) of probability density functions (PDFs) <inline-formula> <tex-math notation="LaTeX">$\geq 70$ </tex-math></inline-formula>% accuracy, overlap coefficients, and percentile-based thresholding, which provide a more comprehensive assessment of model performance, capturing not only accuracy but also confidence and ambiguity in predictions. …”
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Machine learning-driven benchmarking of China's wastewater treatment plant electricity consumption by Minjian Li, Chongqiao Tang, Junhan Gu, Nianchu Li, Ahemaide Zhou, Kunlin Wu, Zhibo Zhang, Hui Huang, Hongqiang Ren

“…To overcome the complexity of wastewater compositions, an unsupervised machine learning algorithm, spectral clustering, is introduced to analyze 2,576 WWTPs across China, effectively characterizing influent quality as a single variable and contributing to robust benchmarks with 75 % of the fittings achieving coefficients of determination (R2) >0.85. …”
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