Impact of IgG subclass on monoclonal antibody developability by Paul Cain, Lihua Huang, Yu Tang, Victor Anguiano, Yiqing Feng

“…We thus conducted a systematic study of 12 mAbs derived from three sets of unrelated variable regions, each cloned into IgG1, an IgG1 variant with diminished effector functions, IgG2, and a stabilized IgG4 variant with further reduced FcγR interaction, to evaluate the impact of IgG subclass on manufacturability and high concentration stability in a common formulation buffer matrix. …”
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Bayesian inference for peak feature extraction and prediction of material property in X-ray diffraction data by Ryo Murakami, Taisuke T. Sasaki, Hideki Yoshikawa, Yoshitaka Matsushita, Keitaro Sodeyama, Tadakatsu Ohkubo, Hiroshi Shinotsuka, Kenji Nagata

“…We challenge peak feature extraction in the situation where only the peak function profile is known a priori, without knowledge of the measurement material or crystal structure factor. …”
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Fast 3D localization of nano-objects in wide-field interferometric scattering microscopy via vectorial diffraction model-derived analytical fitting by Liaoliao Wei, Caroline Livan Anyi, Huakun Li, Haitao Nie, Bihan Wen, Tong Ling

“…The simplified analytic function includes a quadratically scaling amplitude term and a linearly scaling phase term, both of which change with the nano-object’s axial position. …”
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Predicting and Mapping of Soil Organic Matter with Machine Learning in the Black Soil Region of the Southern Northeast Plain of China by Yiyang Li, Gang Yao, Shuangyi Li, Xiuru Dong

“…The estimation of soil organic matter (SOM) content is essential for understanding the chemical, physical, and biological functions of soil. It is also an important attribute reflecting the quality of black soil. …”
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Social capital as a determinant of quality of life in greek cancer patients: a cross-sectional study by Athanasios Pitis, Maria Diamantopoulou, Aspasia Panagiotou, Dimitrios Papageorgiou, Foteini Tzavella

“…The association between QoL and Social capital scales was checked via Spearman correlation coefficients (rho).ResultsGreater total score in Social capital scale was significantly associated with greater overall QoL (β = 0.005; p < 0.001), better Emotional functioning (β = 0.004; p = 0.004) and better Social functioning (β = 0.009; p = 0.002),with lower Nausea and vomiting (β = −0.017; p = 0.015), Insomnia (β = −0.014; p = 0.002), Appetite loss (β = −0.010; p = 0.018) and Constipation symptoms (β = −0.009; p = 0.047).ConclusionThere was a strong association between a greater social capital score and the quality of life of Greek cancer patients, indicating that higher levels of social capital are associated with improved quality of life.…”
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Deep Learning Approaches for Morphological Classification of Intestinal Organoids by Giovanni Cicceri, Sebastiano Di Bella, Simone Di Franco, Giorgio Stassi, Matilde Todaro, Salvatore Vitabile

“…The use of deep learning (DL) in organoid image analysis becomes crucial to handle complexity, variability, and large amounts of data efficiently and accurately, overcoming the limitations of traditional image processing approaches. …”
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Application of machine learning algorithms for predicting the life-long physiological effects of zinc oxide Micro/Nano particles on Carum copticum by Maryam Mazaheri-Tirani, Soleyman Dayani, Majid Iranpour Mobarakeh

“…All ML algorithms showed varied efficiencies in predicting the nonlinear relationships among parameters, with higher efficiency in predicting the behavior of root and shoot dry mass, root fresh weight and number of flowers according to R2 index. …”
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Cross-sectional associations between physical activity and sedentary time with cardiovascular health in children from the ALSPAC study using compositional data analysis by K. M. Sansum, B. Bond, R. M. Pulsford, A. McManus, A. O. Agbaje, A. M. Skinner, A. R. Barker

“…Abstract This study adopted a compositional framework to cross-sectionally examine the associations between physical activity (PA) and sedentary time (ST) with vascular structure and function and clustered cardiovascular disease (CVD) risk factors in 4277 children (2,226 girls), aged 10.6±0.2 years. …”
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Organizational and Economic Factors of Health System Optimization by Oleksandr Telizhenko, Yuliia Halynska, Nataliia Baistriuchenko, Volodymyr Potseluiev, Kateryna Demchuk

“…To this aim, the factors that influence the efficiency of the organization and functioning of the medical system are identified. …”
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PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival by Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik

“…This is typically done by ex vivo stimulation with cytokines to enhance functionality or expansion for 10-14 days to increase both their activity and quantity. …”
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Reverse Active Modification Method of Tooth Profile for RV Reducer Cycloidal Gear by Xiaotao An, Tianxing Li, Chunrong Xing, Guofeng Wang, Meng Tian

“…></graphic></alternatives></inline-formula> of the parabolic modification method are taken as the modification variables of the tooth profile, and the mathematical model of the reverse modification of the tooth profile is established with the minimum transmission error as the objective function. …”
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Words of Mouth on Destination Images and Intentions to Revisit

“…These results highlight the critical function of EWOM in reinforcing positive destination perceptions and encouraging repeat visits. …”
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Mild Cognitive Impairment and Cardiometabolic Risk Factors in Bosnian and Herzegovinian Patients with Heart Failure by Jasna Ibrahimović-Pašić, Orhan Lepara, Amela Dervišević, Nermina Babić, Nesina Avdagić, Amina Valjevac, Asija Začiragić

“…Associations between categorical variables and correlation coefficients were assessed by the Chi-square and Spearman test, respectively. …”
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Research on the Inversion of Key Growth Parameters of Rice Based on Multisource Remote Sensing Data and Deep Learning by Jian Li, Jian Lu, Hongkun Fu, Wenlong Zou, Weijian Zhang, Weilin Yu, Yuxuan Feng

“…Dehui City in Jilin Province, China, was selected as the case study area, where multidimensional data including vegetation indices, ecological function parameters, and environmental variables were collected, covering seven key growth stages of rice. …”
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Spatiotemporal Analysis and Anomalous Trends of Asia AOD (2001–2024): Insights from a Deep Learning Fusion Model and EOF Decomposition by Yu Ding, Wenjia Ni, Jiaxin Dong, Jie Yang, Shiyao Meng, Siwei Li

“…To overcome these challenges, this study employs the deep learning model TabNet, incorporating Digital Elevation Model (DEM) data and ERA5 meteorological variables, to fuse MERRA-2 AOD with MODIS MAIAC AOD observations. …”
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An Investigation on Health Literacy and Its Impact on Health-Promoting Behaviors among the Residents of Mashhad by Mohammad Hasan Sharbatiyan

“…The beta regression findings indicate that the functional, relational, critical, and fundamental components significantly influence the dependent variable, with a percentage correlation value of 69% respectively. …”
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INVARIANTS OF GENERALIZED RAPOPORT-LEAS EQUATIONS by E. N. Kushner

“…For the generalized Rapoport-Leas equations, algebra of differential invariants is constructed with respect to point transformations, that is, transformations of independent and dependent variables. The finding of a general transformation of this type reduces to solving an extremely complicated functional equation. …”
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Serum Interleukin-6, Interleukin-17A, and transforming growth factor beta are raised in systemic sclerosis with interstitial lung disease by Anupam Wakhlu, Rasmi Ranjan Sahoo, Jyoti Ranjan Parida, Mohit K Rai, Durga P Misra, Vinita Agrawal, Vikas Agarwal

“…Serum IL-6, IL-17A and TGF β1 levels were assayed using ELISA kit and compared among disease subtypes and clinical parameters. Spearman coefficient was used to test correlation between continuous variables. …”
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The Relationship between Calcium-phosphorus Metabolism Disorder and Cognitive Impairment in Maintenance Hemodialysis Patients by Geng Ming-hui, Li Yu-yan, Tao Mi, Liao Wen-wen, He Yi-qing, Gao Ping

“…Montreal Cognitive Assessment （MoCA） scale was utilized for evaluating overall cognitive function. They were divided into two groups of cognitive impairment and non-cognitive impairment. …”
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Incorporating Traffic Flow Model into A Deep Learning Method for Traffic State Estimation: A Hybrid Stepwise Modeling Framework by Yuyan Annie Pan, Jifu Guo, Yanyan Chen, Siyang Li, Wenhao Li

“…We build a hybrid cost function to adjust the weights of model-driven and data-driven proportions. …”
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