Optimization of K-Shaped Metal Sealing Ring for Subsea Tubing Hanger Based on Response Surface Method by Huan Xie, Hongxia Zhang, Yiwei Fan, Liyuan Liu, Wei Zeng

“…To address the issue of low optimization efficiency due to the need for repeated finite element calculations during the optimization process, quadratic response surface models are established for the sealing performance indicators of the K-shaped seal ring, which were then used as the optimization objective functions to enhance the optimization efficiency. …”
Get full text

Deep Learning Approaches for Morphological Classification of Intestinal Organoids by Giovanni Cicceri, Sebastiano Di Bella, Simone Di Franco, Giorgio Stassi, Matilde Todaro, Salvatore Vitabile

“…The use of deep learning (DL) in organoid image analysis becomes crucial to handle complexity, variability, and large amounts of data efficiently and accurately, overcoming the limitations of traditional image processing approaches. …”
Get full text

Impact of pulmonary rehabilitation in sleep in COPD patients measured by actigraphy. by Suman B Thapamagar, Kathleen Ellstrom, James D Anholm, Ramiz A Fargo, Nagamani Dandamudi

“…Paired comparisons (t-test or Wilcoxon-signed-rank test) were performed before and after PR data on all variables.<h4>Methods</h4>This retrospective study of COPD patients undergoing PR utilized actigraphy watch recordings before and after 8-weeks of PR to assess changes in sleep variables including total time in bed (TBT), total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), wakefulness after sleep onset (WASO) and total nocturnal awakenings. …”
Get full text

RAMAS-Net: a module-optimized convolutional network model for aortic valve stenosis recognition in echocardiography by Yejia Gan, Wanzhong Huang, Yan Deng, Xiaoying Xie, Yuanyuan Gu, Yaozhuang Zhou, Qian Zhang, Maosheng Zhang, Yangchun Liu

“…IntroductionAortic stenosis (AS) is a valvular heart disease that obstructs normal blood flow from the left ventricle to the aorta due to pathological changes in the valve, leading to impaired cardiac function. Echocardiography is a key diagnostic tool for AS; however, its accuracy is influenced by inter-observer variability, operator experience, and image quality, which can result in misdiagnosis. …”
Get full text

Post-thaw dimethyl sulfoxide reduction in autologous peripheral blood progenitor cell suspensions by Miroslava Jandová, Pavel Měřička, Jiří Gregor, Miriam Lánská, Aleš Bezrouk, Dana Čížková, Jakub Radocha

“…Background and objectives: Dimethyl sulfoxide has become the most common cryoprotectant used for cryopreservation of hematopoietic progenitor cells because of its efficiency, regardless of its potentially toxic side effects. …”
Get full text

The MiBlend Randomized Trial: Investigating Genetic Polymorphisms in Personalized Responses to Fruit and Vegetable Interventions for Chronic Disease Prevention by Julia N. DeBenedictis, Na Xu, Theo M. de Kok, Simone G. van Breda

“…As with most dietary intervention studies, inter-individual variability was observed in the responses, which might be the consequence of genetic differences. …”
Get full text

Developing a machine learning model for fast economic optimization of solar power plants using the hybrid method of firefly and genetic algorithms, case study: optimizing solar the... by Ali Omidkar, Razieh Es'haghian, Hua Song

“…The objective functions were to optimize the exergy efficiency and the heat cost. …”
Get full text

Reconfiguration of dynamic brain networks in heart failure with preserved ejection fraction: Linking neurovascular coupling and cardiac dysfunction by Xiulin Liang, Qinghua Zhang, Chuanlong Zhang, Jingjing Liu, Pengcheng Sang, Qing Mao, Lei Wang

“…Results: (1) Static network topology properties exhibited significantly decreased local network efficiency among patients with HFpEF. The connectivity strength and information processing efficiency were diminished in the left parahippocampal gyrus, left cingulate gyrus, and right insular gyrus brain regions, and improved in the left thalamus, right fusiform gyrus, and right precuneus regions. (2) Dynamic network topology properties of patients with HFpEF showed decreased variability in critical nodes and brain subregions (e.g., the superior frontal gyrus, left amygdala, and left fusiform gyrus) and compensatory increases in the variability of specific regions (e.g., right insular gyrus, right postcentral gyrus, and right temporal gyrus). (3) In HFpEF, the static and dynamic functional brain network topology properties of the fusiform gyrus, cingulate gyrus, superior temporal gyrus, precuneus, parahippocampal gyrus, insular gyrus, and amygdala regions were significantly correlated with cardiac structural and functional indices, such as LVDd, LVMI, and E/e′ ratio. …”
Get full text

Copula Modeling and Uncertainty Propagation in Field‐Scale Simulation of CO2 Fault Leakage by Per Pettersson, Eirik Keilegavlen, Tor Harald Sandve, Sarah E. Gasda, Sebastian Krumscheid

“…The uncertainty in upscaled flow functions and other uncertain parameters are efficiently propagated to leakage estimates using numerical reservoir simulation of a two‐phase system of CO2 and brine. …”
Get full text

Adaptive Stochastic Approach for Evaluating Service Level Using a (SIM-ESL) Module Developed for Optimizing Product Availability and Order Accuracy by Aufy Samah A., Jabbar Rasha, Shiaa Waad Q.

“…It is structured with two models are: Evaluation Dynamic Maximum Economic Order Quantity (EDEOQ) model developed Artificial Neural Network (ANN) to evaluate the optimum inventory level of finished goods as a function of product varied demand and lead time. The second one, Variability Between-Among Dynamic Economic Order Quantity (VB-ADEOQ) is modeled a fuzzy logic to estimate the performance measures (AOP and AOO) that make sure the required order is being processed and delivered on time. …”
Get full text

End-to-End Stroke Imaging Analysis Using Effective Connectivity and Interpretable Artificial Intelligence by Wojciech Ciezobka, Joan Falco-Roget, Cemal Koba, Alessandro Crimi

“…The goal of this pipeline is to define an efficient brain representation for connectivity in stroke data derived from magnetic resonance imaging. …”
Get full text

Flow Characteristics of Distinctly Viscous Multilayered Intestinal Fluid Motion by S. K. Pandey, M. K. Chaube, Dharmendra Tripathi

“…The goal of this investigation is to study the three layered (core layer, intermediate layer, and peripheral layer) tubular flow of power law fluids with variable viscosity by peristalsis in order to investigate the strength of the role played by an artificially generated intermediate layer to ease constipation. …”
Get full text

High-accuracy solution of pantograph differential equations subject to mixed boundary conditions via shifted Vieta–Lucas polynomials by R. M. Hafez, H. M. Ahmed

“…A Galerkin method (GM) is formulated for constant coefficient-type equations, and a spectral collocation method (SCM) is given for variable coefficient cases. The basis functions are developed to fulfill the given MTBCs, which reduces implementation and enhances accuracy. …”
Get full text

Adaptability to Teleworking in European Countries by Aniela Bălăcescu, Aurelia Pătrașcu, Loredana Maria Păunescu

“…The limits of the research are related to the involvement of only six variables, the analysis can be extended in future research to other variables as well.…”
Get full text

Cost-effective model of building construction based on GREENSHIP rating assessment using value engineering and lifecycle cost analysis methods by Sutikno Sutikno, Sarwono Hardjomuljadi, Henny Wiyanto

“…Abstract Regulation No. 21 of 2021, issued by the Minister of Public Works and Public Housing, mandates green building performance assessments for Building Approval (PBG) and Certificate of Functional Worthiness (SLF). However, many stakeholders perceive green building investments as costly. …”
Get full text

Classification of medical imaging technologies: results from Türkiye by Hakan Temiz, Tuncay Kara

“…It also suggests that regional utilization patterns may align more with functional similarities than with geographic proximity. …”
Get full text

Mechatronic system for running-in and testing of mechanical transmissions in mining shovels by Sergey I. Malafeev, Alevtina A. Malafeeva, Vladimir I. Konyashin, Andrey A. Novgorodov

“…The mechanical transmissions of the hoist and drag winches, as well as the crowd mechanisms of mining shovels, operate under highly variable and shock cyclic loads. These severe operating conditions impose stringent quality requirements on both the manufacturing and assembly of such transmissions. …”
Get full text

Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…Using productivity as a standard is useful for calculating efficiency, and can guide efforts to allocate resources optimally. …”
Get full text

Integrating multi-dimensional data to reveal the mechanisms and molecular targets of baikening granules for treatment of pediatric influenza by Zhaoyuan Gong, Qianzi Che, Mingzhi Hu, Tian Song, Lin Chen, Haili Zhang, Ning Liang, Huizhen Li, Guozhen Zhao, Lijiao Yan, Xuefei Zhang, Bin Liu, Jing Guo, Nannan Shi

“…The high risk of viral variability, drug resistance, and drug development leads to a scarcity of therapeutic drugs. …”
Get full text

Factors Influencing Telemedicine Adoption Among Health Care Professionals: Qualitative Interview Study by Fiona Schürmann, Daniel Westmattelmann, Gerhard Schewe

“…Perceived benefits encompassed convenience through reduced travel time (5/14, 36%), improved care quality due to higher accessibility (8/14, 57%), and operational efficiency (7/14, 50%). Trust referents played a pivotal role; trust in technology was linked to functionality (6/14, 43%) and reliability (5/14, 36%), while trust in treatment depended on effective collaboration (9/14, 64%). …”
Get full text