A differential diagnostic model based on immunological evaluation and routine laboratory tests: distinguishing multiple myeloma from other disorders with aberrant immunoglobulin el... by Manning Li, Sixun Jia, Han Wu, Chunyi Shou, Xiaolu Song, Ye Peng, Huafang Wang, Ying Wang, Xiangmin Tong, Yirui Chen

“…Laboratory indicators, including complete blood count, biochemistry, coagulation function, and immunoglobulin markers, were collected. …”
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New Patient PROMIS Scores of Patients Presenting with Low Back Pain Predict Time to Elective Spine Surgery by Justin E. Kung, Chase Gauthier, Yianni Bakaes, Michael Spitnale, Richard A. Bidwell, David G. Edelman, Heidi C. Ventresca, J. Benjamin Jackson, Shari Cui, Gregory Grabowski

“…A chart review was conducted to collect sociodemographic variables, clinic visit details, and PROMIS domain scores (PF [Physical Function], PI [Pain Interference], Depression, and Global Health―Physical and Global Health―Mental). …”
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Clinical diagnostic and prognostic value of homocysteine combined with hemoglobin [f (Hcy-Hb)] in cardio-renal syndrome caused by primary acute myocardial infarction by Min-Juan Zeng, Yan-Quan Liu, Ping Pang, Xiao-Jun Chen, He Huang, Rui-Na Huang, Shi-Sen Li, He-Hui Zhang, Yue Yin, Chang-Sen Wang, Jin-Da Lin, Lin Lin, Shao-Peng Chen, Li Xu, Liang-Qing Zhang

“…Conclusion The newly constructed function [f (Hcy-Hb)], integrating Hcy and Hb levels, exhibits robust diagnostic and prognostic value in CRS. …”
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Protein expression profiling identifies a prognostic model for ovarian cancer by Luyang Xiong, Jiahong Tan, Yuchen Feng, Daoqi Wang, Xudong Liu, Yun Feng, Shusheng Li

“…The prognostic effect and the biological function of the model were evaluated using co-expression analysis and enrichment analysis. …”
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‘‘Practices and factors affecting on-site medical equipment maintenance at Wau Teaching Hospital, South Sudan’’ by Natale Massimino Ucin, Manassé Nimpagaritse, Shital Mahindra Maru, Mulatedzi Makhado, Shiferaw Mitiku Tebeka

“…Abstract Background of the study Along with developments in the clinical domain, medical equipment is becoming more sophisticated, and it needs to function at peak efficiency. In this case, hospitals should priorities the prompt and effective maintenance of life-saving equipment. …”
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Effect of Central Motor and Neuromuscular Impairments on Front Crawl Body Roll Characteristics of Para Swimmers by Yu-Hsien Lee, Dawn Nicola O’Dowd, Luke Hogarth, Brendan Burkett, Carl Payton

“…CMNI swimmers were divided into three upper-limb [mild (n = 9), moderate (n = 9), severe (n = 9)] and three lower-limb function subgroups [bilateral (n = 2), unilateral (n = 6), without kick (n = 19)] based on their Froude efficiency (a measure of how effectively upper limbs contribute to propulsion) and the number of lower limbs actively kicking during trials, respectively. …”
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Agronomic Information Extraction from UAV-Based Thermal Photogrammetry Using MATLAB by Francesco Paciolla, Giovanni Popeo, Alessia Farella, Simone Pascuzzi

“…Nowadays, these sensors can be integrated as payloads on unmanned aerial vehicles, providing high spatial and temporal resolution, to deeply understand the variability of crop and soil conditions. However, few commercial software programs, such as PIX4D Mapper, can process thermal images, and their functionalities are very limited. …”
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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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Building Credible VTOL Flight Models for Handling Quality Certification by Simulation by Lorenzo Favaro, Agata Rylko, Giuseppe Quaranta

“…Applied to a lift + cruise VTOL model performing a deceleration-to-hover manoeuvre, the study demonstrates that while longitudinal control dynamics largely remained within MUAD limits, indicating the model’s credibility for those aspects, vertical axis dynamics coupled with longitudinal inputs for some uncertain configurations exceeded these limits, correlating with observed flight test performance variability. Readers will find a structured, quantitative approach to model validation for HQ certification by simulation, leveraging MUAD to determine if a nominal model is sufficiently representative for certification, thereby supporting safer and more efficient VTOL development.…”
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The role of personalized precision medicine in enhancing diagnostic accuracy and clinical outcomes by Shamala Devi Sekaran, Rishya Manikam, Gaythri Thergerajan, Haymond Prasad, Munandy Alagar, Chung Keat Tan

“…Autologous or allogeneic stem cells such as mesenchymal stem cells and induced pluripotent stem cells can be used for direct tissue treatment in a rapid, personalized, and efficient manner. This approach of engineering cells and altering their functions before clinical use offers numerous benefits that are essential for personal health.…”
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The Brain Behind the Grid: A Comprehensive Review on Advanced Control Strategies for Smart Energy Management Systems by Gowthamraj Rajendran, Reiko Raute, Cedric Caruana

“…The integration of digital technologies is catalysing a fundamental transformation of modern energy systems, enhancing operational efficiency, adaptability, and sustainability. Despite significant progress, the existing literature often addresses digital innovations in isolation, with limited consideration of their synergistic potential within Advanced Energy Systems (AES). …”
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Preparation of Trop2-targeted chimeric antigen receptor T cells and study of their exhaustion status in vitro by LIU Xiuying, LI Xinzhan, ZHU Jingjing, ZHU Jingjing

“…Methods‍　‍The second-generation CAR plasmid was constructed based on the single-chain variable fragment (scFv) sequence of Sacituzumab Govitecan targeting Trop2. …”
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Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential by Niza Otero-Guzman, Ricardo Andrade-Pizarro

“…However, there are several challenges associted with the efficient extraction and accurate characterization of these compounds, including the complexity of plant matrices, variability in compound polarity, and the need for scalable, eco-friendly methods that preserve their bioactivity. …”
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Analysis of MAXIM Application Service Quality on User Satisfaction using the E-Service Quality Method by Putri Wulandari, Nur Rachman Dzakiyullah, Asti Ratnasari, Dadang Heksaputra

“…Overall, the quality of Maxim's service towards user satisfaction is not good in terms of the variables of efficiency, system availability, responsiveness, and contact. …”
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Hemodynamic homeostasis disequilibrium in critical illness by Jie Wang, Xiaoting Wang, Dawei Liu, Hui Lian, Guangjian Wang, Zewen Tong, Qingyu Deng, Qirui Guo, Qian Zhang, Yangong Chao, Wanhong Yin

“…Such balance is essential for sustaining cellular metabolism and maintaining the function of vital organs throughout embryonic development and the human lifespan. …”
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Modeling and optimizing the atmospheric water harvesting System: Application of PAN-PDMS polymeric membrane by Sepehr Sanaye, Pouya Rezvani Gil Kalaee, Javad Mahmoudimehr

“…The water production rate and the total annual cost rate were considered as two objective functions. Also, five design variables are selected after considering their effects on the objective functions. …”
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Framework for extracting multi-objective operation rules for cascade reservoirs based on causal features and physical mechanisms by Donglin Gu, Baowei Yan, Jianbo Chang, Yixuan Zou, Dongxu Yang, Mingbo Sun, Xiaoyu Diao

“…To reduce high dimensionality, Convergent Cross Mapping (CCM) quantifies causal relationships between features and decision variables. Moreover, embedding physical constraints into the model’s loss function further enhances interpretability. …”
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PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival by Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik

“…This is typically done by ex vivo stimulation with cytokines to enhance functionality or expansion for 10-14 days to increase both their activity and quantity. …”
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Transcriptome profiling of Hyacinthus orientalis L. cultivars in floral pigmentation by Kwan-Ho Wong, Hoi-Yan Wu, Cheryl Wood-Yee Shum, Jerome Ho-Lam Hui, Pang-Chui Shaw, David Tai-Wai Lau

“…In addition, the usability of the dataset was demonstrated by the identification of differentially expressed genes, functional annotation and functional enrichment analysis. …”
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Advanced microfluidic strategies for core-shell nanoparticles: the next-generation of polymeric and lipid-based drug nanocarriers by Giuseppe Nunziata, Alessandro Borroni, Filippo Rossi

“…Microfluidic technology has transformed the synthesis of core-shell nanoparticles (CSNPs), providing an unprecedented level of control over their structural and functional properties. This review critically evaluates recent advancements, highlighting the superiority of microfluidic methods over conventional batch techniques, which often suffer from variability and scalability issues. …”
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