Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developin... by Akihiko Kawahara, Tetsuro Sasada, Koichi Azuma, Hidenobu Ishii, Norikazu Matsuo, Takaaki Tokito, Tomoaki Hoshino, Yohei Miyagi, Huihui Xiang, Tomoyuki Tagami, Rika Kasajima, Yumiko Kato, Sachise Karakawa, Shinya Kikuchi, Akira Imaizumi, Kenta Murotani

“…Background Amino acid metabolism is essential for tumor cell proliferation and regulation of immune cell function. However, the clinical significance of free amino acids (plasma-free amino acids (PFAAs)) and tryptophan-related metabolites in plasma has not been fully understood in patients with non-small cell lung cancer (NSCLC) who receive immune checkpoint inhibitors.Methods We conducted a single cohort observational study. …”
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Modelling Geographically Weighted Truncated Spline Regression Using Maximum Likelihood Estimation for Human Development Disparities by Laode Muhammad Saris, Henny Pramoedyo, Adji Achmad Rinaldo Fernandes

“…Among these, the Bi-Square weighting function performed the best, achieving a coefficient of determination of 99.999%, demonstrating the model’s capability to explain nearly all data variability effectively. …”
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Research and development of thick plate shape prediction system based on industrial big data by Yufei MA, Changxin LIU, Wei KONG, Jinliang DING

“…Thick plate shape is one of the important indicators to measure the quality of thick plate products.The timely prediction of the final plate shape in production is of great significance for adjusting the operation and control of thick plate production.In actual industrial production, thick plate data has many characteristics, such as multiple coupling information, large amount of redundant information, and multi-source heterogeneity of data.Combining the needs of thick plate shape prediction, a thick plate shape prediction system was designed and developed.The data dump function was used to filter and preprocess the industrial big data to remove the coupling information and redundant variables in the data.LSTM neural network, convolutional neural network and 3D convolutional neural network were used to extract data features from data of different dimensions, and the features were fused based on the maximum mutual information coefficient to establish an integrated learning prediction model, which effectively solved the modeling difficulties caused by multi-source heterogeneous data.The actual industrial data of a domestic thick plate production line was used for verification, and the results showed the effectiveness of the developed system.…”
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On the approximation of sum of lognormal for correlated variates and implementation. by Asyraf Nadia Mohd Yunus, Nora Muda, Abdul Rahman Othman, Sonia Aïssa

“…In probabilistic modeling across engineering, finance, and telecommunications, sums of lognormal random variables frequently occur, yet no closed-form expression exists for their distribution. …”
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Neutral Mode Dominates the Forced Global and Regional Surface Temperature Response in the Past and Future by Fukai Liu, Jian Lu, L. Ruby Leung

“…Abstract Using a large suite of Green's function perturbation experiments, we construct the emergent dynamical operator for surface temperature and extract the most excitable mode. …”
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An Adiabatic-Expansion-Induced Perturbation Study on Gas–Aerosol Partitioning in Ambient Air—Formation of NH₄NO₃ and Microdroplet Nitrogen Fixation (2) by Yating Gao, Qinchu Fan, Yujiao Zhu, Hengqing Shen, Qi Yuan, Yang Gao, Huiwang Gao, Xiaohong Yao

“…Our results indicate the adiabatic-expansion-induced generation of NH₃ + HNO₃ at ultrafast formation rates, with campaign-dependent stable stoichiometric ratios of HNO₃ to NH₃, as well as highly variable occurrence frequencies and efficiencies. These findings suggest that microdroplet redox reactions are more likely responsible for the generation of NH₃ + HNO₃ than conventional atmospheric NH₃ chemistry. …”
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Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau by WANG Zhenliang, CHEN Manyu, ZHAO Jianlin, YUAN Ke, YANG Jie, ZHANG Chen

“…Then the correlations between rainfall factors and landslide shape variables were calculated to determine the rainfall days and effective rainfall attenuation coefficient in the early period. …”
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Degradation of Tetracycline in Wastewater by Persulfate Activated by Sulfidated Nanometer Zero-valent Iron by Qiuyue YE, Zhengchun HU, Ziyi WANG, Wen XU, Shiyi ZHAO, Xuying DENG, Minghao GUO, Na GUO, Bing LIAO

“…Sulfidated zero-valent iron (S–nZVI) has been extensively utilized in wastewater treatment in recent years due to its superior electron transfer efficiency and selectivity. Integrating S–nZVI with advanced oxidation technology enhances the catalytic performance of the material, leading to efficient pollutant degradation. …”
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The influence of fitness mobile apps on workout behavior intention among Chinese young adults. by Mengyu Li, Shujie Wang, Abdul Rahim Ahmed Soliman Darweesh

“…Three components of belief were examined: self-efficiency, perceived barriers, and perceived benefits. …”
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Double and integer multi-objective optimization of solar HDH desalination system with bubble column dehumidifier: An artificial neural network approach by Alireza Naeini, Alireza Jalali, Ehsan Houshfar

“…A neural network model is utilized to predict how the objective functions vary with six decision variables. The chosen optimization approach utilizes the genetic algorithm (GA) method. …”
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Adaptive neighbourhood for locally and globally tuned biogeography based optimization algorithm by Parimal Kumar Giri, Sagar S. De, Satchidananda Dehuri

“…BBO has demonstrated good performance on various unconstrained and constrained benchmark functions. It has also been applied to real world optimization problems of type linear or nonlinear, nominal or ordinal as well as mixed variables. …”
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Steady-State Dynamical Response of a Strongly Nonlinear System with Impact and Coulomb Friction Subjected to Gaussian White Noise Excitation by Guidong Yang, Dongmei Huang, Wei Li, Meng Su

“…The Zhuravlev nonsmooth transformation of the state variables combined with the Dirac delta function is utilized to simplify the original system to one without velocity jump. …”
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Application of a novel metaheuristic algorithm inspired by connected banking system in truss size and layout optimum design problems and optimization problems by Mehrdad Nemati, Yousef Zandi, Jamshid Sabouri

“…Abstract Optimum design of truss structures can be a challenging and difficult field of study specially if an optimum design problem is comprised of continuous and discrete decision variables such as in truss size and layout optimization problems. …”
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A New Modeling Method for Meteorological Information of Regional Distributed Photovoltaic Power Generation Based on Multi‐Source Information Fusion by Yuhang Wang, Dengxuan Li, Wenwen Ma, Xi Zhang, Honglu Zhu

“…Precise meteorological information is the foundation for achieving these functions. However, DPV sites are typically scattered with small installed capacities and generally lack dedicated weather stations. …”
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International Natural Uranium Price Prediction Based on TF-CNN-BiLSTM Model by YANG Jingzhe, XUE Xiaogang

“…The study meticulously constructed and trained the TF-CNN-BiLSTM model using TensorFlow with the Adam optimizer and mean squared error loss function. The training process was optimized with learning rate reduction and early stopping callbacks to prevent overfitting. …”

eDNAjoint: An R package for interpreting paired or semi‐paired environmental DNA and traditional survey data in a Bayesian framework by Abigail G. Keller, Ryan P. Kelly

“…Abstract Environmental DNA (eDNA) sampling is increasingly used in surveys of species distribution as a potentially sensitive and efficient monitoring method. Yet access to modelling tools designed specifically for interpreting this new data type lags behind its ubiquity. …”
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Automated Geographic Information System Multi-Criteria Decision Tool to Assess Urban Road Suitability for Active Mobility by Bertha Santos, Sandro Ferreira, Pollyanna Lucena

“…The Model Builder functionality available in ArcGIS^® was used to automate the various processes required to calculate walking, cycling, and e-biking travel times, as well as the mobility indices. …”
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Experimental Study and Damage Model Study of Rock Salt Subjected to Cyclic Loading and Cyclic Creep by Baoyun Zhao, Tianzhu Huang, Liu Dongyan, Dongsheng Liu, Yang Liu, Xiaoping Wang

“…The damage model is obtained by inverse functioning the s function, and then the correction coefficient is added to the model to obtain the modified damage model. …”
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Experimental Studies of Heat and Moisture Exchange in the Process of Convective Drying of Thin Wet Materials by A. I. Ol’shanskii, S. V. Zhernosek, A. M. Gusarov

“…New ways of experimental data processing by generalized complex variables that are characteristic of the drying process are presented. …”
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Sap flow simulation of Cunninghamia lanceolata in degraded red soil region based on back propagation neural network by Tu Jie, Liu Qijing, Wei Jun, Hu Liang

“…Therefore, quantitative research on tree water consumption characteristics by transpiration has become a hot issue in the field of tree physiological ecology in recent years.Taking the C. lanceolata plantation in degraded red soil of Jiangxi Province as the research object, the log-sigmoid type function (tansig) of MATLAB toolbox was selected as the transmission function for the role of neurons. …”
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