Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
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Assessment of Outcomes of the Modified Stoppa Approach in the Treatment of Acetabular Fractures: A Retrospective Cohort Study by Nurgeldi Manap, Nagmet Mursalov, Mukhtar Abilmazhinov

“…Exclusion criteria: other operative approaches to pelvic bones and patients under 18 years of age. 21 patients underwent surgery with the use of modified Stoppa approach (group A) and 10 surgeries were performed using the ilioinguinal approach (group B). Efficiency was evaluated by comparison of duration of surgical procedures, amount of blood lossbetween groups, size of skin incision, quality of reduction and functional outcomes. …”
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Development and evaluation of a predictive model of upper gastrointestinal bleeding in liver cirrhosis by Jin Peng, Huiru Jin, Ningxin Zhang, Shiqiu Zheng, Chengxiao Yu, Jianzhong Yu, Longfeng Jiang

“…Once bleeding occurs, the risk of recurrent episodes substantially increases, further compromising liver function and worsening patient outcomes. This study aims to identify risk factors for UGIB in cirrhotic patients using clinical examination data and to develop a non-invasive predictive model to improve diagnostic precision and efficiency. …”
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Potential Protective Effect of Orlistat: A Formulation of Nanocrystals Targeting Inflammation, Oxidative Stress, and Apoptosis in an Experimental Model of Doxorubicin-Induced Cardi... by Maha Alsunbul, Thanaa A. El-Masry, Enas I. El Zahaby, Mohamed M. S. Gaballa, Maysa M. F. El-Nagar

“…The study results indicated that DOX caused significant cardiotoxicity, as revealed by a remarkable rise in cardiac function biomarkers like LDH and CK-MB, which involve enzyme activities. …”
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The agricultural plastic paradox: Feeding more, harming more? by Kai Wang, Xuejun Liu, David R. Chadwick, Changrong Yan, Michaela Reay, Tida Ge, Fan Ding, Jingkuan Wang, Ruimin Qi, Mouliang Xiao, Rui Jiang, Yanling Chen, Ji Ma, Charlotte Lloyd, Richard P. Evershed, Yongming Luo, Yongguan Zhu, Fusuo Zhang, Davey L. Jones

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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…Using productivity as a standard is useful for calculating efficiency, and can guide efforts to allocate resources optimally. …”
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TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1 by Christina Funk, Nadja Uhlig, Zsolt Ruzsics, Florentin Baur, Matthias Peindl, Sarah Nietzer, Karina Epting, Gabriele Vacun, Gudrun Dandekar, Catherine Botteron, Christian Werno, Thomas Grunwald, Susanne M. Bailer

“…Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. …”
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Neutral Mode Dominates the Forced Global and Regional Surface Temperature Response in the Past and Future by Fukai Liu, Jian Lu, L. Ruby Leung

“…Abstract Using a large suite of Green's function perturbation experiments, we construct the emergent dynamical operator for surface temperature and extract the most excitable mode. …”
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Influence of structural surface roughness on the strength of layered fill bodies based on PFC2D by Jinxing WANG, Zongsheng HU, Huazhe JIAO, Xiaolin YANG, Qi ZHANG, Xiaohui LIU, Ping XU, Junqiang XU, Xun CHEN

“…The relationship between cemented surface roughness and backfill strength is examined by analyzing variables such as cemented surface roughness, mass fraction of slurry, cement-to-sand ratio, and filling interval time. …”
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Degradation of Tetracycline in Wastewater by Persulfate Activated by Sulfidated Nanometer Zero-valent Iron by Qiuyue YE, Zhengchun HU, Ziyi WANG, Wen XU, Shiyi ZHAO, Xuying DENG, Minghao GUO, Na GUO, Bing LIAO

“…Sulfidated zero-valent iron (S–nZVI) has been extensively utilized in wastewater treatment in recent years due to its superior electron transfer efficiency and selectivity. Integrating S–nZVI with advanced oxidation technology enhances the catalytic performance of the material, leading to efficient pollutant degradation. …”
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Exploring the nexus of many-body theories through neural network techniques: the tangent model by Senwei Liang, Karol Kowalski, Chao Yang, Nicholas P Bauman

“…The NN representation not only allows us to evaluate the effective interactions efficiently for various geometrical configurations of chemical systems corresponding to various levels of complexity of the underlying wave functions, but also reveals that the bare and effective interactions are related by a tangent function of some latent variables. …”
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Impacts of early postpartum behavioral patterns on the fertility and milk production of tropical dairy cows by Aqeel Raza, Kumail Abbas, Theerawat Swangchan-Uthai, Henk Hogeveen, Chaidate Inchaisri

“…Reproductive performance was analyzed using Cox proportional hazard models, while lactation dynamics were modeled using the Wood function to estimate peak yield, peak time, and persistency. …”
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Adsorption of Cd (II) Using Chemically Modified Rice Husk: Characterization, Equilibrium, and Kinetic Studies by Javier Montalvo-Andía, Warren Reátegui-Romero, Alexis D. Peña-Contreras, Walter F. Zaldivar Alvarez, María E. King-Santos, Víctor Fernández-Guzmán, José Luis Guerrero-Guevara, Jhon E. Puris-Naupay

“…In optimal experimental conditions, the maximum adsorption efficiency was 92.65%. Fourier-transform infrared spectroscopy (FTIR) and scanning electron microscope (SEM) were used allowing the identification of the main functional groups and morphology of rice husk and treated rice husk, and the results showed an improvement of adsorption characteristics after rice husk treatment with NaOH. …”
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Effect of design and kinematic parameters on energy requirement in inclined screw mixer by V. F. Khlystunov, S. V. Braginets, A. S. Alferov, M. V. Chernutskiy

“…The establishment of functional dependences between parameters and modes enables to design power-efficient equipment for the on-farm feed production.Materials and Methods. …”
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The Analysis of the Effective Factors on Urban Blight in District 3, Region 12, Tehran City by Hossein Mansourian, Ahmad Pour Ahmad, Hasan Ashouri

“…Moreover, a factor analysis was employed to reduce the number of independent variables and identify the urban blight dimensions. …”
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Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry by Mark A. Fogel, Jennifer A. Faerber, Abdullah Mahmood, Keerthi Reddy, Xuemei Zhang, Elizabeth Goldmuntz, Matthew A. Harris, David Biko, Sara Partington, Stephen Paridon, Michael Mcbride, Victor Ferrari, Kevin K. Whitehead, Laura Mercer‐Rosa

“…An elastic net was used to identify significant variables to enter a best subsets logistic regression. …”
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Optimization of fermentation conditions for enhanced acetylcholine and biomass production of Lactiplantibacillus plantarum AM2 using the Taguchi approach by Walid A. Lotfy, Amira M. Ali, Heba M. Abdou, Khaled M. Ghanem

“…Abstract This study aimed to optimize the fermentation conditions and medium composition for maximum acetylcholine (ACh) and biomass production by Lactiplantibacillus plantarum AM2 using the Taguchi array design, which enables efficient identification of influential variables through minimal experimental runs. …”
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Unveiling Theranostics: Nanocomplex-Assisted Photodynamic Eradication of Aggressive Cancer Cells and Modulation of Tumor-Associated Macrophages by Butkute A, Kazlauske E, Mlynska A, Peciukaityte E, Karabanovas V, Rotomskis R, Steponkiene S

“…The nanocomplex accumulated efficiently and uniformly across all CRC cell lines, regardless of their aggressiveness or drug sensitivity. …”
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Optimized Blade Design of Counter-Rotating-Type Pump-Turbine Unit Operating in Pump and Turbine Modes by Jin-Woo Kim, Jun-Won Suh, Young-Seok Choi, Kyoung-Yong Lee, Toshiaki Kanemoto, Jin-Hyuk Kim

“…The pump and turbine mode efficiencies of the unit were selected as the objective functions and they combined into a single specific objective function with the weighting factors. …”
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Elucidating Genotypic Variation in Quinoa via Multidimensional Agronomic, Physiological, and Biochemical Assessments by Samreen Nazeer, Muhammad Zubair Akram

“…The results revealed that significant variation was observed across all measured parameters, highlighting the diverse adaptive strategies and functional capacities among the tested genotypes. More specifically, genotypes Q4, Q11, Q15, and Q126 demonstrated superior agronomic potential and canopy-level physiological efficiencies, including high biomass accumulation, low infrared canopy temperatures and sustained NDVI values. …”
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