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901
Bayesian inference of structured latent spaces from neural population activity with the orthogonal stochastic linear mixing model.
Published 2024-04-01“…The brain produces diverse functions, from perceiving sounds to producing arm reaches, through the collective activity of populations of many neurons. …”
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902
Unraveling novel variants in the NF1 gene and investigating potential therapeutic strategies
Published 2025-07-01“…A retrospective analysis of 49 clinical trials over the past 20 years revealed that NF1 therapies predominantly target neurofibromin’s GTPase function. Gene therapies aiming to restore neurofibromin by transducing the truncated NF1-GRD gene have been developed but faced pre-clinical challenges, including cloning capacity, transduction efficiency, and immunogenicity caused by gene delivery. …”
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903
SCIENTIFIC APPROACH TO A COMPLEX ASSESSMENT OF DETERMINANTS OF THE INSURANCE MARKET DEVELOPMENT OF UKRAINE
Published 2019-03-01“…The developed model contains a clear list and sequence of stages of the insurance market analysis and a specific methodology for assessing the impact of key factors, characteristic for changing conditions of management, on the efficiency of its functioning. Practical application allows to take into consideration the influence of individual determinants of the insurance market development on its condition, to increase the efficiency of managerial decisions in this area. …”
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904
Impacts of early postpartum behavioral patterns on the fertility and milk production of tropical dairy cows
Published 2025-05-01“…Reproductive performance was analyzed using Cox proportional hazard models, while lactation dynamics were modeled using the Wood function to estimate peak yield, peak time, and persistency. …”
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905
Alleviative Effect of Exogenous Application of Fulvic Acid on Nitrate Stress in Spinach (<i>Spinacia oleracea</i> L.)
Published 2024-10-01“…FA application promoted the accumulation of biomass in spinach under nitrate stress and increased chlorophyll content, the net photosynthetic rate, the maximum photochemical quantum yield of PSII (Photosystem II) (Fv/Fm), the quantum efficiency of PSII photochemistry [Y(II)], the electron transport rate, and the overall functional activity index of the electron transport chain between the PSII and PSI systems (PItotal); moreover, FA decreased PSII excitation pressure (1 − qP), quantum yields of regulated energy dissipation of PSII [Y(NPQ)], and the relative variable initial slope of fluorescence. …”
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906
Environmental impacts of floating solar panels on freshwater systems and their techno-ecological synergies
Published 2024-01-01“…However, understanding of the ecological consequences for water bodies is very limited despite the variable and far-reaching range of potential impacts. …”
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907
Non-Similar Analysis of Boundary Layer Flow and Heat Transfer in Non-Newtonian Hybrid Nanofluid over a Cylinder with Viscous Dissipation Effects
Published 2025-03-01“…Non-similar system of PDEs are obtained with efficient conversion variables. The dimensionless PDEs are truncated using a local non-similarity approach up to third level and numerical solution is evaluated using MATLAB built-in-function bvp4c. …”
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908
Design and Simulation of Ornithopter based on Four-bar Mechanism
Published 2017-01-01“…The model is established by MATLAB/SimMechanics,and the four-bar mechanism of the robot is simulated and integrated into the iSIGHT software to optimize the parameters and obtain the design variable value similar to the expected trajectory. …”
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909
Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry
Published 2025-05-01“…An elastic net was used to identify significant variables to enter a best subsets logistic regression. …”
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910
Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy.
Published 2012-01-01“…This is rapid and blinding in a colony of dogs in which the mutation was characterised but in dogs with the same mutation in the pet population there is very variable disease severity and rate of progression.<h4>Objective</h4>We hypothesized that this variability must be associated with leakiness of the RPGRIP1 mutation, allowing continued RPGRIP1 production. …”
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911
Fuzzy System for the Quality Assessment of Educational Multimedia Edition Design
Published 2025-04-01“…A multilevel model of fuzzy logical inference is constructed, representing the dependency between quality factors. Membership functions for linguistic variables are formed and their weight coefficients are determined using pairwise comparison matrices. …”
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912
Vibration Analysis of Rotating Tapered Timoshenko Beams by a New Finite Element Model
Published 2006-01-01“…This procedure reduces the number of nodal variables. The new model can also be used for uniform beams. …”
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913
Clinical diagnostic and prognostic value of homocysteine combined with hemoglobin [f (Hcy-Hb)] in cardio-renal syndrome caused by primary acute myocardial infarction
Published 2025-07-01“…Conclusion The newly constructed function [f (Hcy-Hb)], integrating Hcy and Hb levels, exhibits robust diagnostic and prognostic value in CRS. …”
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914
Optimization of the Fc-fusion protein refolding method produced from the bacterial expression system
Published 2025-03-01“…Increasing the buffer pH led to improved refolding efficiency.…”
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915
The Hydrodynamic Performance of a Vertical-Axis Hydro Turbine with an Airfoil Designed Based on the Outline of a Sailfish
Published 2025-06-01“…Through Latin hypercube experimental design combined with optimization algorithms, four key geometric variables governing the airfoil’s hydrodynamic characteristics were systematically analyzed. …”
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916
p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system.
Published 2011-01-01“…<h4>Methodology/principal findings</h4>Given the many factors that might influence p53 function, including expression levels, mutations, cofactor proteins and small molecules, we expanded our previously described yeast-based system to provide the opportunity for efficient investigation of their individual and combined impacts in a miniaturized format. …”
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917
Optimal power flow using recent red-tailed hawk optimization algorithm
Published 2025-03-01“…Optimization can efficiently achieve various objective functions in power systems. …”
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918
Hybrid data-driven and physics-informed regularized learning of cyclic plasticity with neural networks
Published 2024-01-01“…The mean squared error is assumed as the loss function which stipulates several restrictions: deviatoric character of internal variables, compliance with the flow rule, the differentiation of elastic and plastic steps and the associativity of the flow rule. …”
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919
Polynomial Chaos Expansion Approach to Interest Rate Models
Published 2015-01-01“…The Polynomial Chaos Expansion (PCE) technique allows us to recover a finite second-order random variable exploiting suitable linear combinations of orthogonal polynomials which are functions of a given stochastic quantity ξ, hence acting as a kind of random basis. …”
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920
Distributed generation plants multi-agent controlling system
Published 2017-12-01“…The adaptability of the system against variable conditions and applicability of the multi-agent technologies during creation of electric power supply smart grids was demonstrated.…”
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