Bayesian inference of structured latent spaces from neural population activity with the orthogonal stochastic linear mixing model. by Rui Meng, Kristofer E Bouchard

“…The brain produces diverse functions, from perceiving sounds to producing arm reaches, through the collective activity of populations of many neurons. …”
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Unraveling novel variants in the NF1 gene and investigating potential therapeutic strategies by Jianmei Huang, Ke Yang, Yaoping Wang, Xinrui Ma, Wenke Yang, Xiaodong Huo, Jie Bai, Hongjie Zhu, Jinming Wang, Yibing Lv, Shixiu Liao

“…A retrospective analysis of 49 clinical trials over the past 20 years revealed that NF1 therapies predominantly target neurofibromin’s GTPase function. Gene therapies aiming to restore neurofibromin by transducing the truncated NF1-GRD gene have been developed but faced pre-clinical challenges, including cloning capacity, transduction efficiency, and immunogenicity caused by gene delivery. …”
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SCIENTIFIC APPROACH TO A COMPLEX ASSESSMENT OF DETERMINANTS OF THE INSURANCE MARKET DEVELOPMENT OF UKRAINE by L. V. Popova, N. O. Kovalchuk, D. D. Polagnyn

“…The developed model contains a clear list and sequence of stages of the insurance market analysis and a specific methodology for assessing the impact of key factors, characteristic for changing conditions of management, on the efficiency of its functioning. Practical application allows to take into consideration the influence of individual determinants of the insurance market development on its condition, to increase the efficiency of managerial decisions in this area. …”
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Impacts of early postpartum behavioral patterns on the fertility and milk production of tropical dairy cows by Aqeel Raza, Kumail Abbas, Theerawat Swangchan-Uthai, Henk Hogeveen, Chaidate Inchaisri

“…Reproductive performance was analyzed using Cox proportional hazard models, while lactation dynamics were modeled using the Wood function to estimate peak yield, peak time, and persistency. …”
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Alleviative Effect of Exogenous Application of Fulvic Acid on Nitrate Stress in Spinach (<i>Spinacia oleracea</i> L.) by Kangning Han, Jing Zhang, Cheng Wang, Youlin Chang, Zeyu Zhang, Jianming Xie

“…FA application promoted the accumulation of biomass in spinach under nitrate stress and increased chlorophyll content, the net photosynthetic rate, the maximum photochemical quantum yield of PSII (Photosystem II) (Fv/Fm), the quantum efficiency of PSII photochemistry [Y(II)], the electron transport rate, and the overall functional activity index of the electron transport chain between the PSII and PSI systems (PItotal); moreover, FA decreased PSII excitation pressure (1 − qP), quantum yields of regulated energy dissipation of PSII [Y(NPQ)], and the relative variable initial slope of fluorescence. …”
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Environmental impacts of floating solar panels on freshwater systems and their techno-ecological synergies by Sofia M G Rocha, Alona Armstrong, Stephen J Thackeray, Rebecca R Hernandez, Andrew M Folkard

“…However, understanding of the ecological consequences for water bodies is very limited despite the variable and far-reaching range of potential impacts. …”
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Non-Similar Analysis of Boundary Layer Flow and Heat Transfer in Non-Newtonian Hybrid Nanofluid over a Cylinder with Viscous Dissipation Effects by Ahmed Zeeshan, Majeed Ahmad Yousif, Muhammad Imran Khan, Muhammad Amer Latif, Syed Shahzad Ali, Pshtiwan Othman Mohammed

“…Non-similar system of PDEs are obtained with efficient conversion variables. The dimensionless PDEs are truncated using a local non-similarity approach up to third level and numerical solution is evaluated using MATLAB built-in-function bvp4c. …”
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Design and Simulation of Ornithopter based on Four-bar Mechanism by Zhao Zhifang, Qi Mingsi, Feng Jingkai, Zhang Wei, Wang Junyuan, Zhang Jiping

“…The brushless motor driving two stage reducer,provides input for four-bar mechanism. The robot has a function of the periodic flapping motion,the frequency change and size of the attitude angle adjustment. …”
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Clinical Outcome Prediction Model in Tetralogy of Fallot Without Pulmonary Valve Replacement Using Contraction Fraction From the SCOUT‐TOF Registry by Mark A. Fogel, Jennifer A. Faerber, Abdullah Mahmood, Keerthi Reddy, Xuemei Zhang, Elizabeth Goldmuntz, Matthew A. Harris, David Biko, Sara Partington, Stephen Paridon, Michael Mcbride, Victor Ferrari, Kevin K. Whitehead, Laura Mercer‐Rosa

“…An elastic net was used to identify significant variables to enter a best subsets logistic regression. …”
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Multiple mechanisms contribute to leakiness of a frameshift mutation in canine cone-rod dystrophy. by Keiko Miyadera, Ian Brierley, Jesús Aguirre-Hernández, Cathryn S Mellersh, David R Sargan

“…This is rapid and blinding in a colony of dogs in which the mutation was characterised but in dogs with the same mutation in the pet population there is very variable disease severity and rate of progression.<h4>Objective</h4>We hypothesized that this variability must be associated with leakiness of the RPGRIP1 mutation, allowing continued RPGRIP1 production. …”
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Fuzzy System for the Quality Assessment of Educational Multimedia Edition Design by Vsevolod Senkivskyy, Liubomyr Sikora, Nataliia Lysa, Alona Kudriashova, Iryna Pikh

“…A multilevel model of fuzzy logical inference is constructed, representing the dependency between quality factors. Membership functions for linguistic variables are formed and their weight coefficients are determined using pairwise comparison matrices. …”
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Vibration Analysis of Rotating Tapered Timoshenko Beams by a New Finite Element Model by Bulent Yardimoglu

“…A new finite element model is developed and subsequently used for transverse vibrations of tapered Timoshenko beams with rectangular cross-section. The displacement functions of the finite element are derived from the coupled displacement field (the polynomial coefficients of transverse displacement and cross-sectional rotation are coupled through consideration of the differential equations of equilibrium) approach by considering the tapering functions of breadth and depth of the beam. …”
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Clinical diagnostic and prognostic value of homocysteine combined with hemoglobin [f (Hcy-Hb)] in cardio-renal syndrome caused by primary acute myocardial infarction by Min-Juan Zeng, Yan-Quan Liu, Ping Pang, Xiao-Jun Chen, He Huang, Rui-Na Huang, Shi-Sen Li, He-Hui Zhang, Yue Yin, Chang-Sen Wang, Jin-Da Lin, Lin Lin, Shao-Peng Chen, Li Xu, Liang-Qing Zhang

“…Conclusion The newly constructed function [f (Hcy-Hb)], integrating Hcy and Hb levels, exhibits robust diagnostic and prognostic value in CRS. …”
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Optimization of the Fc-fusion protein refolding method produced from the bacterial expression system by P. S. Astrelina, S. A. Ishchuk, A. V. Kabanova, R. V. Drai

“…The production of Fc-fused proteins in prokaryotic systems often results in the formation of insoluble aggregates due to improper folding of polypeptide chains. To obtain functional proteins, a refolding step is required. However, developing refolding parameters can be time-consuming. …”
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The Hydrodynamic Performance of a Vertical-Axis Hydro Turbine with an Airfoil Designed Based on the Outline of a Sailfish by Aiping Wu, Shiming Wang, Chenglin Ding

“…Through Latin hypercube experimental design combined with optimization algorithms, four key geometric variables governing the airfoil’s hydrodynamic characteristics were systematically analyzed. …”
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p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system. by Virginia Andreotti, Yari Ciribilli, Paola Monti, Alessandra Bisio, Mattia Lion, Jennifer Jordan, Gilberto Fronza, Paola Menichini, Michael A Resnick, Alberto Inga

“…<h4>Methodology/principal findings</h4>Given the many factors that might influence p53 function, including expression levels, mutations, cofactor proteins and small molecules, we expanded our previously described yeast-based system to provide the opportunity for efficient investigation of their individual and combined impacts in a miniaturized format. …”
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Optimal power flow using recent red-tailed hawk optimization algorithm by Ahmed M Nassef, Mohammad Ali Abdelkareem, Mohamed Louzazni

“…The optimal power flow (OPF) solution determines the most efficient and secure operating point by considering certain objective functions and ensuring the system's operational restrictions are met. …”
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Hybrid data-driven and physics-informed regularized learning of cyclic plasticity with neural networks by Stefan Hildebrand, Sandra Klinge

“…The mean squared error is assumed as the loss function which stipulates several restrictions: deviatoric character of internal variables, compliance with the flow rule, the differentiation of elastic and plastic steps and the associativity of the flow rule. …”
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Polynomial Chaos Expansion Approach to Interest Rate Models by Luca Di Persio, Gregorio Pellegrini, Michele Bonollo

“…The Polynomial Chaos Expansion (PCE) technique allows us to recover a finite second-order random variable exploiting suitable linear combinations of orthogonal polynomials which are functions of a given stochastic quantity ξ, hence acting as a kind of random basis. …”
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Distributed generation plants multi-agent controlling system by YU. N. Bulatov, A. V. Kryukov

“…The framework of multi-agent controlling system (MACS) is proposed in the article in order to control the power of distributed generation plants, implemented on the basis of turbine-type alternatives. The major functions of the agents, forming an interactive network are described. …”
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