Unraveling novel variants in the NF1 gene and investigating potential therapeutic strategies by Jianmei Huang, Ke Yang, Yaoping Wang, Xinrui Ma, Wenke Yang, Xiaodong Huo, Jie Bai, Hongjie Zhu, Jinming Wang, Yibing Lv, Shixiu Liao

“…A retrospective analysis of 49 clinical trials over the past 20 years revealed that NF1 therapies predominantly target neurofibromin’s GTPase function. Gene therapies aiming to restore neurofibromin by transducing the truncated NF1-GRD gene have been developed but faced pre-clinical challenges, including cloning capacity, transduction efficiency, and immunogenicity caused by gene delivery. …”
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Synergistic co-metabolism enhancing the crude oil degradation by Acinetobacter oleivorans DR1 and its metabolic potential by Lairenjam Paikhomba Singha, Renuka Kumari, Keisam Malabika Singha, Piyush Pandey, Pratyoosh Shukla

“…ABSTRACT Bacterial degradation of hydrocarbons during co-metabolism with glucose often resulted in variable degradation efficiency. This study explored the mechanistic understanding of the metabolic response during co-metabolism in Acinetobacter oleivorans DR1 using a metabolomics approach. …”
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An Investigation on Health Literacy and Its Impact on Health-Promoting Behaviors among the Residents of Mashhad by Mohammad Hasan Sharbatiyan

“…The beta regression findings indicate that the functional, relational, critical, and fundamental components significantly influence the dependent variable, with a percentage correlation value of 69% respectively. …”
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INVARIANTS OF GENERALIZED RAPOPORT-LEAS EQUATIONS by E. N. Kushner

“…For the generalized Rapoport-Leas equations, algebra of differential invariants is constructed with respect to point transformations, that is, transformations of independent and dependent variables. The finding of a general transformation of this type reduces to solving an extremely complicated functional equation. …”
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Adaptive Model Predictive Control for 4WD-4WS Mobile Robot: A Multivariate Gaussian Mixture Model-Ant Colony Optimization for Robust Trajectory Tracking and Obstacle Avoidance by Hayat Ait Dahmad, Hassan Ayad, Alfonso García Cerezo, Hajar Mousannif

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Physics-augmented deep learning models for improving evapotranspiration estimation in global land regions by Binrui Liu, Xinguang He, Wenkai Lyu, Lizhi Tao

“…A Physics-Data Learning (PDL) model is first formed by adding a complementary physical variable generated by Penman–Monteith (PM) equation to a deep learning (DL) model along with driving variables to regress latent heat flux. …”
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An Empirical Analysis of Herding Behavior in the Stock Market: Evidence from Various Economic and Social Conditions in Iran by Majid Aghaei

“…This approach models the response of the dependent variable to the independent variable at various quantiles, denoted as "τ," making it an effective tool for analyzing non-normal distributions. …”
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Ammonia Gas Adsorption in Fixed Bed and Fluidized Bed Using Bentonite Particles by Gabriela Muntianu, Ana-Maria Georgescu, Ana-Maria Rosu, Nicoleta Platon, Vasilica Alisa Arus, Cosmin Valeriu Jinescu, Ileana Denisa Nistor

“…Fluidized bed adsorption can be an efficient technique to accelerate mass transfer between ammonia from air and adsorbent particles.…”
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Neuro-fuzzy inference system and white shark optimization of coagulation-flocculation of aquaculture wastewater treatment by A.F. Mohamed, H. Rezk

“…During the optimization process, these controlling parameters are used as a design variable whereas the objective function required to me be a maximum is the summation of turbidity removal and salinity removal. …”
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Application of marine bacterial alginate lyases in wastewater treatment, biofilm removal and green technology by M.U.K. Anjung, H. Nursyam, A.A. Prihanto, E. Chasanah

“…Despite notable progress, challenges remain in achieving efficient large-scale production, enhancing enzyme robustness, and fine-tuning catalytic properties. …”
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Intelligent hybrid method to predict generated power of solar PV system by Prashant Singh, Navneet Kumar Singh, Asheesh Kumar Singh

“…The input solar PV power data are broken down into intrinsic mode functions (IMFs) using EMD technique is fed into the PSO-ANFIS, along with important meteorological variables. …”
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Reverse Active Modification Method of Tooth Profile for RV Reducer Cycloidal Gear by Xiaotao An, Tianxing Li, Chunrong Xing, Guofeng Wang, Meng Tian

“…></graphic></alternatives></inline-formula> of the parabolic modification method are taken as the modification variables of the tooth profile, and the mathematical model of the reverse modification of the tooth profile is established with the minimum transmission error as the objective function. …”
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Words of Mouth on Destination Images and Intentions to Revisit

“…These results highlight the critical function of EWOM in reinforcing positive destination perceptions and encouraging repeat visits. …”
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Engineering safe anti-CD19-CD28ζ CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy by Muthuganesh Muthuvel, Muthuganesh Muthuvel, Thamizhselvi Ganapathy, Trent Spencer, Sunil S. Raikar, Saravanabhavan Thangavel, Alok Srivastava, Alok Srivastava, Alok Srivastava, Sunil Martin

“…CARs are modular synthetic antigen receptors integrating the single-chain variable fragment (scFv) of an immunoglobulin molecule to the TCR signaling. …”
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A Fusion Method Based on Physical Modes and Satellite Remote Sensing for 3D Ocean State Reconstruction by Yingxiang Hong, Xuan Wang, Bin Wang, Wei Li, Guijun Han

“…This study developed an operational-oriented lightweight framework for three-dimensional ocean state reconstruction by integrating multi-source observations through a computationally efficient multivariate empirical orthogonal function (MEOF) method. …”
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On the Nonlinear Forced Vibration of the Magnetostrictive Laminated Beam in a Complex Environment by Nicolae Herisanu, Bogdan Marinca, Vasile Marinca

“…The nonlinear differential equations were studied using an original, explicit, and very efficient technique, namely the optimal auxiliary functions method (OAFM). …”
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Associations between patient characteristics and five-year trajectories of anticholinergic drug burden in older adults in German primary care: a prospective observational cohort st... by Hans-Helmut König, Claudia Langebrake, Steffi G Riedel-Heller, Martin Scherer, Gerhard Schön, Ingmar Schäfer, Dagmar Lühmann, Birgitt Wiese, Jochen Gensichen, Caroline Krüger, Horst Bickel, Angela Fuchs, Wolfgang Maier, Karola Mergenthal, Siegfried Weyerer, Daniel Tajdar, Juliane Westphal

“…Independent variables included age, sex, education (according to CASMIN), depressiveness (GDS), cognitive function (LDST), quality of life (EQ5D-3L) and the number of diseases weighted by severity. …”
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Cost-effective process design for methanol synthesis from carbon dioxide hydrogenation by Sheng-Zhong Huang, Chih-Yao Lin, Chianghui Wang, Akhmat Fauzan Saputra, Henggar Yudha Hananto, Nicolas Justin Sutanto, Anggit Raksajati, Vincentius Surya Kurnia Adi

“…Accordingly, this research introduces an optimization framework capable of handling diverse process configurations, operating variables, and their interactions. This approach enables effective optimization using total annual cost (TAC) as the objective function and significantly enhances process design efficiency. …”
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Multi-Objective Optimal Design of 200 kW Permanent Magnet Synchronous Motor Based on NSGA-II by Chengxu Sun, Qi Li, Tao Fan, Xuhui Wen, Ye Li, Hongyang Li

“…Interior permanent magnet synchronous motors (IPMSMs) are widely applied as drive motors in electric vehicles because they have the advantages of high power density, high efficiency, and excellent dynamic performance. This paper introduces a framework for multi-objective optimization, tailored for the demands of V-Shaped IPMSMs, which involves high-dimensional variables. …”
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COVID-19 recovery: benefits of multidisciplinary respiratory rehabilitation by Wim Janssens, Greet Hermans, Rik Gosselink, Daniel Langer, Thierry Troosters, Hilde Beyens, Stephanie Everaerts, Arne Heyns, Natalie Lorent

“…Impressive results on physical recovery were determined after 6 weeks and 3 months, with significant improvement of lung function, muscle force and exercise capacity variables. …”
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