Development of blood-brain barrier-penetrating antibodies for neutralizing tick-borne encephalitis virus in the brain by Mizuki Fukuta, Sayo Fukano, Naoya Maekawa, Shintaro Kobayashi, Shunsuke Okamoto, Minato Hirano, Junko Nio-Kobayashi, Hiroaki Kariwa, Shigeru Kawakami, Satoru Konnai, Kentaro Yoshii

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Antigen-independent activation is critical for the durable antitumor effect of GUCY2C-targeted CAR-T cells by Xiaofei Wei, Lin Shen, Chang Liu, Cheng Zhang, Min Tao, Jian Li, Xicheng Wang, Ting He, Fei Dai, Changsong Qi, Mingyang Ma, Yanping Ding, Xinan Lu, Dongqun Liu

“…An antigen-sensitive and long-lasting CAR-T cell targeting GUCY2C was investigated in this study.Methods Using constructed tumor cell lines with various GUCY2C expression densities, we screened out an antigen-sensitive single chain variable fragment (scFv) that enabled CAR-T cells to efficiently eradicate the GUCY2C lowly expressed tumor cells. …”
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RAMAS-Net: a module-optimized convolutional network model for aortic valve stenosis recognition in echocardiography by Yejia Gan, Wanzhong Huang, Yan Deng, Xiaoying Xie, Yuanyuan Gu, Yaozhuang Zhou, Qian Zhang, Maosheng Zhang, Yangchun Liu

“…IntroductionAortic stenosis (AS) is a valvular heart disease that obstructs normal blood flow from the left ventricle to the aorta due to pathological changes in the valve, leading to impaired cardiac function. Echocardiography is a key diagnostic tool for AS; however, its accuracy is influenced by inter-observer variability, operator experience, and image quality, which can result in misdiagnosis. …”
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Post-thaw dimethyl sulfoxide reduction in autologous peripheral blood progenitor cell suspensions by Miroslava Jandová, Pavel Měřička, Jiří Gregor, Miriam Lánská, Aleš Bezrouk, Dana Čížková, Jakub Radocha

“…Background and objectives: Dimethyl sulfoxide has become the most common cryoprotectant used for cryopreservation of hematopoietic progenitor cells because of its efficiency, regardless of its potentially toxic side effects. …”
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Multi-objective optimal scheduling of cascade reservoirs in complex basin systems: Case study of the Jinsha River-Yalong River confluence basin in China by Zhaocai Wang, Zhihua Zhu, Hualong Luan, Tunhua Wu

“…Benchmark function tests demonstrate that IMOSSA outperforms others in terms of optimization capability and stability. …”
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Shunt active power filter using model predictive control with stability guarantee by Jhon Pérez-Ramírez, Diego Montoya-Acevedo, Walter Gil-González, Oscar Danilo Montoya, Carlos Restrepo

“…The cost function exhibits convex characteristics, ensuring a unique control law. …”
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The MiBlend Randomized Trial: Investigating Genetic Polymorphisms in Personalized Responses to Fruit and Vegetable Interventions for Chronic Disease Prevention by Julia N. DeBenedictis, Na Xu, Theo M. de Kok, Simone G. van Breda

“…As with most dietary intervention studies, inter-individual variability was observed in the responses, which might be the consequence of genetic differences. …”
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Safety Assessment of Loop Closing in Active Distribution Networks Based on Probabilistic Power Flow by Wenchao Cai, Yuan Gao, Xiping Zhang, Qin Si, Jiaoxin Jia, Bingzhen Li

“…By modeling DGs and loads as random variables, their cumulants are efficiently obtained through LHS. …”
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Comparing the Effect of Beractant (Beraksurf™) with That of Poractant Alfa (Curosurf®) on the Need for Intermittent Positive Pressure Ventilation in Neonatal Respiratory Distress S... by Yosra Khazani, Sirous Fathi Manesh, Elnaz Shaseb, Parvin Sarbakhsh

“…Performing appropriate adjusted analysis leads to a more interpretable and efficient estimation of treatment effects. Semiparametric adjustment approach modifies the estimating equations solved by the marginal treatment effect estimator by adding an augmentation function, which makes use of the baseline covariates and estimate the unbiased marginal treatment effect with improved precision. …”
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Computational studies reveal structural characterization and novel families of Puccinia striiformis f. sp. tritici effectors. by Raheel Asghar, Nan Wu, Noman Ali, Yulei Wang, Mahinur Akkaya

“…However, due to the lack of an efficient genetic transformation system in Pst, progress in effector function studies has been slow. …”
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Numerical Investigation and Optimization of Transpiration Cooling Plate Structures with Combined Particle Diameter by Dan Wang, Yaxin Liu, Xiang Zhang, Mingliang Kong, Hanchao Liu

“…An optimization analysis of CPD−PS is conducted using response surface methodology (RSM), and the influence of design variables on the objective function (<i>η</i>_ave and <i>p</i>) is analyzed. …”
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Sustainable PV-hydrogen-storage microgrid energy management using a hierarchical economic model predictive control framework by Xinyu Guo, Faying Gu, Hongxu Liu, Yongcheng Yu, Runjie Li, Juan Wang

“…First, a precise nonlinear model of the PHS microgrid is established and the logic variables are introduced to capture the hydrogen devices’ short-term properties, i.e., the start-up/shut-down of electrolyzers and fuel cells. …”
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Grid-connected PV inverter system control optimization using Grey Wolf optimized PID controller by Monika Gupta, P. M. Tiwari, R. K. Viral, Ashish Shrivastava, Basem Abu Zneid, Iryna Hunko

“…Conventional controllers such as P and PI are widely used in PV applications due to their simplicity, but they exhibit notable limitations in dynamic environments, including increased Total Harmonic Distortion (THD), slower transient response, and poor voltage regulation—particularly under variable irradiance conditions. The proposed GWO-PID method overcomes these limitations by leveraging the GWO algorithm’s global search capability to dynamically optimize the PID gains (Kp, Ki, Kd) based on a composite fitness function that minimizes Mean Squared Error (MSE) and THD. …”
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Research on Geometric Mappings in Complex Systems Analysis by Yanyan Cui, Chaojun Wang, Sifeng Zhu

“…We mainly discuss the properties of a new subclass of starlike functions, namely, almost starlike functions of complex order λ, in one and several complex variables. …”
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Predicting the Cetane Number of Biodiesel using two AI-Models: the Gradient-based ANN and ANN Optimized by Genetic Algorithm by Hadis Tanha, Fatemeh Bashipour

“…The learning function, transfer function, number of hidden layers, and number of neurons in the hidden layers are some of the optimized parameters in the current AI-models. …”
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Predictor Importance for Hydrological Fluxes of Global Hydrological and Land Surface Models by João Paulo L. F. Brêda, Lieke A. Melsen, Ioannis Athanasiadis, Albert VanDijk, Vinícius A. Siqueira, Anne Verhoef, Yijian Zeng, Martine van derPloeg

“…We analyzed the JULES, ORCHIDEE, HTESSEL, SURFEX, and PCR‐GLOBWB models for the relative importance of precipitation, climate, soil, land cover and topographic slope as predictors of simulated average evaporation, runoff, and surface and subsurface runoff. RF models functioned as a metamodel and could reproduce GHM/LSMs outputs with a coefficient of determination (R2) over 0.85 in all cases and often considerably better. …”
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A MODEL OF AGE–STRUCTURED POPULATION UNDER STOCHASTIC PERTURBATION OF DEATH AND BIRTH RATES by Maxim A. Alshanskiy

“…Under consideration is construction of a model of age-structured population reflecting random oscillations of the death and birth rate functions. We arrive at an Itô-type difference equation in a Hilbert space of functions which can not be transformed into a proper Itô equation via passing to the limit procedure due to the properties of the operator coefficients. …”
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THE BONITATION METHOD FOR ASSESSING THE FERTILITY OF THE CHERNOZEM by Mariana BURCEA, Nicoleta OLTENACU

“…Statistical indicators have been determined using the functions from Excel Program, such as: average, standard deviation, coefficient of variability, annual growth rate. …”
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Analytical methods for assessing the quality of sugarcane bagasse compost and improving the physicomechanical properties toward densification by Ehsan Sarlaki, Mohammad Hossein Kianmehr, Marzieh Ghorbani

“…For both responses of specific energy consumption and bulk density of SBCs, a two-factor interaction (2FI) model with the highest correlation coefficient and the lowest standard deviation was proposed. …”
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Inversion of Leaf Chlorophyll Content in Different Growth Periods of Maize Based on Multi-Source Data from “Sky–Space–Ground” by Wu Nile, Su Rina, Na Mula, Cha Ersi, Yulong Bao, Jiquan Zhang, Zhijun Tong, Xingpeng Liu, Chunli Zhao

“…Then, using grey relational analysis (GRA) and the maximum information coefficient (MIC) algorithm, we explored the complex relationship between the vegetation indices (VIs) and LCC, and further selected feature variables. …”
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