High expression of SOX10 is correlated with poor prognosis and immune infiltrates in skin cutaneous melanoma by Xu Sun, Yi-ming Cheng, Meng-wei Sun, Xu-dong Zhang, Xiao-yu Yu, Hai-bo Wang, Yi-fei Wang, Ning Li

“…Screening was performed by LASSO coefficients to select non-zero variables that satisfied the coefficients of lambda, and 8 genes were screened out. …”
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Mandibular reconstruction outcomes for in-house patient-specific solutions by Matthew D. Marquardt, Erin Cowen, Rachel Fenberg, Natalia von Windheim, Margaret Lashutka, Abigail E. Reid, Amit Agarwal, Enver K. Ozer, Ricardo L. Carrau, James W. Rocco, Catherine T. Haring, Stephen Y. Kang, Nolan B. Seim, Matthew O. Old, Kyle K. VanKoevering

“…Inter-rater reliability was assessed via intraclass correlation coefficient. Demographic, clinical, surgical, and radiographic variables were also collected to profile cohort characteristics and outcomes. …”
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Crisis Communication About the Maui Wildfires on TikTok: Content Analysis of Engagement With Maui Wildfire–Related Posts Over 1 Year by Jim P Stimpson, Aditi Srivastava, Ketan Tamirisa, Joseph Keaweʻaimoku Kaholokula, Alexander N Ortega

“…Using TikTok’s search functionality, we identified and reviewed public posts that contained relevant hashtags. …”
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Optimal Design of Interior Permanent Magnet Synchronous Motor Considering Various Sources of Uncertainty by Giacomo Guidotti, Dario Barri, Federico Soresini, Massimiliano Gobbi

“…The method incorporates an innovative use of the neural network-based variance estimation (NNVE) technique to efficiently calculate the standard deviation of the objective functions. …”
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Building Credible VTOL Flight Models for Handling Quality Certification by Simulation by Lorenzo Favaro, Agata Rylko, Giuseppe Quaranta

“…Applied to a lift + cruise VTOL model performing a deceleration-to-hover manoeuvre, the study demonstrates that while longitudinal control dynamics largely remained within MUAD limits, indicating the model’s credibility for those aspects, vertical axis dynamics coupled with longitudinal inputs for some uncertain configurations exceeded these limits, correlating with observed flight test performance variability. Readers will find a structured, quantitative approach to model validation for HQ certification by simulation, leveraging MUAD to determine if a nominal model is sufficiently representative for certification, thereby supporting safer and more efficient VTOL development.…”
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The role of personalized precision medicine in enhancing diagnostic accuracy and clinical outcomes by Shamala Devi Sekaran, Rishya Manikam, Gaythri Thergerajan, Haymond Prasad, Munandy Alagar, Chung Keat Tan

“…Autologous or allogeneic stem cells such as mesenchymal stem cells and induced pluripotent stem cells can be used for direct tissue treatment in a rapid, personalized, and efficient manner. This approach of engineering cells and altering their functions before clinical use offers numerous benefits that are essential for personal health.…”
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A Brief Political Economy of Energy Subsidies in the Middle East and North Africa by Laura El-Katiri, Bassam Fattouh

“…While it is clear that energy subsidy reform will not be the only variable at play, its potential socio-economic dividends are important factors for enabling some common regional objectives—sustainable fiscal policies, fiscal space to invest in key areas, and a more efficient and equitable distribution of scarce resources—to be achieved, helping to promote a more stable political status quo in the long term. …”
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Classification of Biological Data using Deep Learning Technique by Azha Javed, Muhammad Javed Iqbal

“…Previous work failed to properly address issues related to the classification of biological sequences i.e. protein including efficient encoding of variable length biological sequence data and implementation of deep learning based neural network models to enhance the performance of classification/ recognition systems. …”
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Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. by Qi Chen, Luan Jiang, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du

“…The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists. …”
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Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy by M. Willemsen, J. Bulgarelli, S.K. Chauhan, R.R. Lereim, D. Angeli, G. Grisendi, G. Krebbers, I. Davidson, J.A. Kyte, M. Guidoboni, R.M. Luiten, W.J. Bakker

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The potential habitat of Phlomoides rotata in Tibet was based on an optimized MaxEnt model by Jun-Wei Wang, Jun-Wei Wang, Min Xu, Norbu Ngawang, Yonghao Chen, Ngawang Bonjor, Xiaoyan Jia, Zhefei Zeng, Zhefei Zeng, La Qiong, La Qiong

“…IntroductionPhlomoides rotata, an important Tibetan medicinal plant, has garnered significant attention due to its remarkable medicinal value and ecological functions. However, overharvesting and climate change have progressively reduced its distribution range, threatening its survival.MethodsThis study employed an optimized MaxEnt model, integrating field survey data and multiple environmental variables, to predict and analyze the potential suitable distribution of P. rotata in Tibet.ResultsThe model achieved high predictive accuracy, with Ture skill statistic (TSS) = 0.87 and Cohen’s Kappa Coefficient (Kappa) = 0.81. …”
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Concurrent Validity of Wearable Nanocomposite Strain Sensor With Two-Dimensional Goniometer and Its Reliability for Monitoring Knee Active Range of Motion in Multiple Participants by Han-Byeol Choi, Yongjun Kim, Ji Young Lim, Seonghee Kim, Sang Yul Yang, Kihyeon Kim, Hyouk Ryeol Choi, Seunghyun Baik, Ji Hye Hwang

“…The range of motion (ROM) of joints in the human body is essential for movement and functional performance. Real-time monitoring of joint angles is crucial for confirming pathologic biomechanics, providing feedback during rehabilitation, and evaluating the treatment efficacy. …”
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Advanced microfluidic strategies for core-shell nanoparticles: the next-generation of polymeric and lipid-based drug nanocarriers by Giuseppe Nunziata, Alessandro Borroni, Filippo Rossi

“…Microfluidic technology has transformed the synthesis of core-shell nanoparticles (CSNPs), providing an unprecedented level of control over their structural and functional properties. This review critically evaluates recent advancements, highlighting the superiority of microfluidic methods over conventional batch techniques, which often suffer from variability and scalability issues. …”
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La biodiversidad y los servicios ecosistémicos en sistemas agroecológicos. Una revisión by Wendy Mercedes Ramírez-Suárez, Jorge Carlos López-Chouza, María de los Ángeles Flores-Acosta, Saray Sánchez-Cárdenas, Pedro Lázaro Rodríguez-Morejón

“…There is a strong interrelationship between the functioning of biodiversity and the development of ecosystem processes that will subsequently form the basis of production, based on the richness and spatial and temporal variability of species, their performance in the complexity of ecosystems and the maintenance of ecosystem services at different scales.…”
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Symbolic Framework for Evaluation of NOMA Modulation Impairments Based on Irregular Constellation Diagrams by Nenad Stefanovic, Vladimir Mladenovic, Borisa Jovanovic, Ron Dabora, Asutosh Kar

“…This work presents a new symbolic framework approach for simulating signal processing functions in SDR transmit–receive paths in a dynamic NOMA downlink use case. …”
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Role of physical activity on the maintenance of cognition and activities of daily living in elderly with Alzheimer's disease Papel da atividade física na manutenção da cognição e a... by Cynthia Arcoverde, Andréa Deslandes, Aryce Rangel, Andreza Rangel, Robson Pavão, Fortunée Nigri, Eliasz Engelhardt, Jerson Laks

“…BACKGROUND: The practice of physical activities has proved to be an efficient strategy in the improvement of independency and cognitive functions in the elderly with Alzheimer's disease (AD). …”
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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries by Keith Mitchell, Samuel Hunter, Lutz Froenicke, Karl Murray, Matthew Settles, James S. Trimmer

“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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Importance of ice algae versus phytoplankton in the diet of megabenthic organisms under contrasting sea ice conditions (Canadian Arctic): a dual biochemical approach (SIA and HBIs) by Thibaud Combaz, Thibaud Combaz, Ursula Witte, Thomas A. Brown, Philippe Archambault

“…Overall, organisms responded rapidly and efficiently to this pulse of fresh organic matter but trends in resource utilisation (quality and quantity) were observed based on feeding strategy. …”
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Monitoring and benchmarking Earth system model simulations with ESMValTool v2.12.0 by A. Lauer, L. Bock, B. Hassler, P. Jöckel, L. Ruhe, M. Schlund

“…While the examples shown here focus on atmospheric variables, the new functionality can be applied to any other ESM component such as land, ocean, sea ice, or land ice. …”
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Spatio-Temporal Heterogeneity of Vegetation Coverage and Its Driving Mechanisms in the Agro-Pastoral Ecotone of Gansu Province: Insights from Multi-Source Remote Sensing and Geodet... by Macao Zhuo, Jianyu Yuan, Jie Li, Guang Li, Lijuan Yan

“…The multi-scale analytical framework developed here provides methodological and empirical support for precision ecological governance in climate-sensitive transitional zones, particularly for optimizing ecological barrier functions in arid and semi-arid regions.…”
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