Supply chain management and optimization in transportation logistics by Saoussen Krichen

“…SCM can also be seen as the process of optimizing a set of decisions that generate cost-effective solutions which provide efficient plans for acting on numerous levels while considering all decision-making standpoints. …”
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Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Our findings provide the first demonstration that TXA efficiently inhibits MSC-driven plasmin generation by competitively blocking plasminogen binding to the uPA•uPAR complex at the cell plasma membrane.DiscussionWe propose that plasmin formation on MSCs may be involved in pathological processes such as endometrial hemorrhage (metrorrhagia and Post-Partum Hemorrhage), autoimmune and ischaemic diseases, as well as cancer. …”
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Stochastic demethylation and redundant epigenetic suppressive mechanisms generate highly heterogeneous responses to pharmacological DNA methyltransferase inhibition by Mie K. Jakobsen, Sofie Traynor, Aaraby Y. Nielsen, Christina Dahl, Mette Staehr, Simon T. Jakobsen, Maria S. Madsen, Rasmus Siersbaek, Mikkel G. Terp, Josefine B. Jensen, Christina B. Pedersen, Anup Shrestha, Jonathan R. Brewer, Pascal H. G. Duijf, Odd L. Gammelgaard, Henrik J. Ditzel, Alexei F. Kirkin, Per Guldberg, Morten F. Gjerstorff

“…Results We show that breast cancer tumors and cell cultures exhibit a highly heterogenous response to DNA methyltransferase inhibitors, persisting even under high drug concentrations and efficient DNA methyltransferase depletion. The observed variability in response to DNA methyltransferase inhibitors was independent of cancer-associated aberrations and clonal genetic diversity. …”
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Internet News Headlines: Ontological and Orthological Aspects by E. N. Shirokova

“…The author comes to the conclusion that the focus on the variability and efficiency of headings leads not only to the appearance of lexical and grammatical errors, but also to their replication and consolidation in the mind of the addressee as a result of changes in the structure of cognitive models.…”
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Random Fuzzy Power Flow Analysis for Power System considering the Uncertainties of Renewable Energy and Load Demands by J. H. Zheng, Wenting Xiao, Zhigang Li, Q. H. Wu

“…Simulation studies conducted on the IEEE-33 system verifies the accuracy of the RFPF and the efficiency of the 3PE.…”
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Numerical Evaluation of Sound Attenuation Provided by Periodic Structures by Mario MARTINS, Luis GODINHO, Luis PICADO-SANTOS

“…The use of periodic structures as noise abatement devices has already been the object of considerable research seeking to understand its efficiency and see to what extent they can provide a functional solu- tion in mitigating noise from different sources. …”
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Engineering students' perceptions and actual use of AI-based math tools for solving mathematical problems by Kimberly F. Garcia, Ardvin Kester S. Ong, Ma. Janice J. Gumasing, Cesar Romeo V. Delos Reyes

“…The outcome indicated that students are more inclined to utilize AI tools when they find them engaging and are convinced that they can employ them efficiently and incorporate the tools in their academic routines. …”
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Importance of ice algae versus phytoplankton in the diet of megabenthic organisms under contrasting sea ice conditions (Canadian Arctic): a dual biochemical approach (SIA and HBIs) by Thibaud Combaz, Thibaud Combaz, Ursula Witte, Thomas A. Brown, Philippe Archambault

“…Overall, organisms responded rapidly and efficiently to this pulse of fresh organic matter but trends in resource utilisation (quality and quantity) were observed based on feeding strategy. …”
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Optimizing the Construction Supply Chain Network Considering the Flow of Materials, Equipment, Manpower, Drawings and Technical Documents by Seyed Saeid Helli, Hadi Mokhtari, Saeed Dehnavi

“…All indices, parameters, decision variables, objective functions and constraints have been introduced and presented in the proposed model. …”
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Cooperative Control of Interconnected Air Suspension Based on Energy Consumption Optimization by Guoqing Geng, Shuai Zeng, Liqin Sun, Zhongxing Li, Wenhao Yu

“…The optimal interval for suspension force is obtained through solving cost functions while satisfying a set of constraints on controlled variables and thereby reducing the coupling complexity of a multivariable control system. …”
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Binary composite crossover genetic algorithm for locating critical slip surface by Wei Qin, Jiancheng Zhao

“…A reasonable combination of parameters for the binary composite crossover (BCC) operator in the RGA-BCC is determined through six benchmark function experiments. On this basis, the stability of five soil slopes from the literature was analysed using the RGA-BCC in combination with the Morgenstern and Price method, and the results obtained were compared with those in the published literature to demonstrate that the RGA-BCC is able to efficiently determine the CSSs of slopes and their minimum factors of safety. …”
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Estimation of Fuzzy Measures Using Covariance Matrices in Gaussian Mixtures by Nishchal K. Verma

“…The main contribution of this paper is the estimation of fuzzy measures efficiently and directly from covariance matrices found in GMM, avoiding the computational burden greatly while learning them iteratively and solving polynomial equations of order of the number of input-output variables.…”
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Parametric Study of Fuel Distribution Effects on a Kerosene-Based Scramjet Combustor by Jun Yang, Xian-yu Wu, Zhen-guo Wang

“…The fuel equivalence ratio for each injection port was taken as the design variables. And the combustion efficiency, the total pressure recovery coefficient, and the drag coefficient were chosen as the objective functions. …”
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Immunological Avalanches in Renal Immune Diseases by Davide Viggiano, Pietro Iulianiello, Antonio Mancini, Candida Iacuzzo, Luca Apicella, Renata Angela Di Pietro, Sarah Hamzeh, Giovanna Cacciola, Eugenio Lippiello, Andrea Gigliotti, Carmine Secondulfo, Giancarlo Bilancio, Giuseppe Gigliotti

“…Additionally, biological age calculations provide valuable prognostic information, while proteinuria measurements offer efficient sampling for system dynamics assessment. …”
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Machine learning-based model for acute asthma exacerbation detection using routine blood parameters by Youpeng Chen, Junquan Sun, Yabang Chen, Enzhong Li, Jiancai Lu, Huanhua Tang, Yifei Xie, Jiana Zhang, Lesi Peng, Haojie Wu, Zhangkai J. Cheng, Baoqing Sun

“…Background: Acute asthma exacerbations (AAEs) are a leading cause of asthma-related morbidity and mortality, especially in resource-limited settings where pulmonary function tests are unavailable or when patients are unable to cooperate with testing. …”
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Effects of two types of repetitive transcranial magnetic stimulation on brain network in Parkinson’s disease by Shuo Liu, Shuo Yang, Chen Wang, Jiarui Li, Lei Wang

“…The iTBS group showed post-treatment changes involving more brain regions in spatiotemporal variability. This study demonstrates that compared to 10Hz-rTMS, iTBS can reduce treatment time while providing superior improvement in functional brain connectivity for PD patients.…”
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Phenotypic screen of early-developing larvae of the blood fluke, schistosoma mansoni, using RNA interference. by M M Mourão, Nathalie Dinguirard, Glória R Franco, Timothy P Yoshino

“…Although RNAi holds great promise as a functional genomics tool for larval schistosomes, our finding of potential off-target or nonspecific effects of some dsRNA treatments and variable efficiencies in specific gene knockdown indicate a critical need for gene-specific testing and optimization as an essential part of experimental design, execution and data interpretation.…”
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Multiobjective Optimization of Stress-Release Boot of Solid Rocket Motor under Vertical Storage Based on RBF Model by Qiuwen Miao, Huihui Zhang, Zhibin Shen, Weiyong Zhou

“…Stress-release boot can effectively improve the structural integrity of SRM (solid rocket motor), but it will also influence the loading fraction and interior ballistic performance, so the purpose of this paper is to propose a multiobjective optimization method for stress-release boot. The design variables are the front and rear depth of the stress-release boot, and four optimization variables were determined according to the analysis of SRM performance. …”
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Comparative Study of the Impact of Corruption on the Human Development Index by T. M. Zharlygassinov, A. Zh. Panzabekova, M. S. Dosmanbetova

“…The reason for this is the significant negative impact of this phenomenon on the standard of living of citizens and the efficiency of the functioning of state bodies. However, the strength of such interaction may differ depending on the country and how conscientiously the employees of its state apparatus carry out their work. …”
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Statistical Identification of Parameters for Damaged FGM Structures with Material Uncertainties in Thermal Environment by Yalan Xu, Yu Qian, Kongming Guo

“…The numerical simulation results show the efficiency and effectiveness of the presented method for the identification of material parameter variability by using the measurable modal parameters of damaged FGM structures.…”
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