KNOT OPTIMIZATION FOR BI-RESPONSE SPLINE NONPARAMETRIC REGRESSION WITH GENERALIZED CROSS-VALIDATION (GCV) by Andre Fajry Al Barra, Dewi Retno Sari Saputro

“…Nonparametric regression is a statistical method used to model relationships between variables without making strong assumptions about the functional form of the relationship. …”
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The role of personalized precision medicine in enhancing diagnostic accuracy and clinical outcomes by Shamala Devi Sekaran, Rishya Manikam, Gaythri Thergerajan, Haymond Prasad, Munandy Alagar, Chung Keat Tan

“…Autologous or allogeneic stem cells such as mesenchymal stem cells and induced pluripotent stem cells can be used for direct tissue treatment in a rapid, personalized, and efficient manner. This approach of engineering cells and altering their functions before clinical use offers numerous benefits that are essential for personal health.…”
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The Brain Behind the Grid: A Comprehensive Review on Advanced Control Strategies for Smart Energy Management Systems by Gowthamraj Rajendran, Reiko Raute, Cedric Caruana

“…This paper presents a systematic review of key digital technologies—such as artificial intelligence, the Internet of Things, blockchain, and digital twins—employed in AES, providing a critical assessment of their individual functionalities, interdependencies, and collective contributions to the energy sector. …”
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Changes in white matter predict efficacy of repetitive transcranial magnetic stimulation in Parkinson's disease by Jinying Han, Lingling Lv, Xin Chen, Mengqi Wang, Lili Hu, Fengbo Xing, Pingping Liu, Liuzhenxiong Yu, Ziye Zhao, Jinmei Sun, Tingting Liu, Jingjing Cheng, Minhao Zhu, Manman Gao, Gongjun Ji, Rong Ye, Kai Wang, Panpan Hu

“…Conclusion: Baseline WM function may serve as a biomarker for predicting motor response to cTBS.…”
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Bioactive compounds from tropical fruit by-products: Extraction, characterization and therapeutic potential by Niza Otero-Guzman, Ricardo Andrade-Pizarro

“…However, there are several challenges associted with the efficient extraction and accurate characterization of these compounds, including the complexity of plant matrices, variability in compound polarity, and the need for scalable, eco-friendly methods that preserve their bioactivity. …”
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Reference Intervals for Echocardiography Parameters of Children Living in the Arkhangelsk Region and a Digital Application for Their Assessment by Aleksey A Karyakin, Igor’ S. Chub, Ol’ga E. Karyakina, Andrey M. Grjibovski, Aleksey V. Artemov, Ul’yana R. Zakharchenko

“…Reference intervals of echocardiography parameters were determined using body surface area as the dependent variable. The values were automatically calculated in our digital application that allows one to increase the accuracy and efficiency of interpretation of cardiac ultrasound parameters. …”
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Expanding a Health Technology Solution to Address Therapist Challenges in Implementing Homework With Adult Clients: Mixed Methods Study by Brian E Bunnell, Kaitlyn R Schuler, Julia Ivanova, Lea Flynn, Janelle F Barrera, Jasmine Niazi, Dylan Turner, Brandon M Welch

“… BackgroundHomework is implemented with variable effectiveness in real-world therapy settings, indicating a need for innovative solutions to homework challenges. …”
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Impact of IgG subclass on monoclonal antibody developability by Paul Cain, Lihua Huang, Yu Tang, Victor Anguiano, Yiqing Feng

“…We thus conducted a systematic study of 12 mAbs derived from three sets of unrelated variable regions, each cloned into IgG1, an IgG1 variant with diminished effector functions, IgG2, and a stabilized IgG4 variant with further reduced FcγR interaction, to evaluate the impact of IgG subclass on manufacturability and high concentration stability in a common formulation buffer matrix. …”
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Application of Post-Occupancy Evaluation in the Design of Collegiatae Educational Space: (Case study: Faculty of Arts and Architecture, Islamic Azad University-Tehran South Branch) by Reza Naghdbishi, Zeinab Gohari

“…This process led to the development of structural equations, path coefficient models, and factor loadings for the conceptual model.…”
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Assessment of upper limb motor control: establishing normative benchmarks for clinical applications by Pablo Martín-Sierra, Cristina Sanchez, Eloy Urendes, Rafael Raya

“…A combination of clinical functional scales with the quantitative metrics presented here is expected to enable better evaluation of motor control. …”
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Organizational and Economic Factors of Health System Optimization by Oleksandr Telizhenko, Yuliia Halynska, Nataliia Baistriuchenko, Volodymyr Potseluiev, Kateryna Demchuk

“…To this aim, the factors that influence the efficiency of the organization and functioning of the medical system are identified. …”
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Evaluating Machine Learning Models for Predicting Hardness of AlCoCrCuFeNi High-Entropy Alloys by Uma Maheshwera Reddy Paturi, Muhammad Ishtiaq, Pasupuleti Lakshmi Narayana, Anoop Kumar Maurya, Seong-Woo Choi, Nagireddy Gari Subba Reddy

“…This study evaluates the predictive capabilities of various machine learning (ML) algorithms for estimating the hardness of AlCoCrCuFeNi high-entropy alloys (HEAs) based on their compositional variables. Among the ML methods explored, a backpropagation neural network (BPNN) model with a sigmoid activation function exhibited superior predictive accuracy compared to other algorithms. …”
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Meristic and morphometric comparison of an undescribed sucker of the Río Culiacán (Catostomus sp.) and Yaqui sucker (Catostomus bernardini) (Catostomidae, Teleostei) from the Sierr... by Gorgonio Ruiz-Campos, Sergio Sánchez-Gonzáles, Richard L. Mayden, Alejandro Varela-Romero

“…Likewise, the discrimination was associated with the lowest values for predorsal distance, soft posterior ocular margin to occiput, and number of anal rays. The standardized coefficients for canonical variables 1 and 2 accounted 82.6% of the total variation. …”
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Estimativa das temperaturas máximas e mínimas do ar para a região do Circuito das Frutas, SP Estimation of maximum and minimum air temperatures for the "Circuito das Frutas" region... by Ludmila Bardin, Mário J. Pedro Júnior, Jener F. L. de Moraes

“…The obtained correlation coefficients varied from 0.91 to 0.96 and 0.71 to 0.94 of the maximum and minimum air temperature, respectively. …”
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Sensitivity to Instruction Strategies in Motor Learning Is Predicted by Anterior–Posterior TMS Motor Thresholds by Michael L. Perrier, Kylee R. Graham, Jessica E. Vander Vaart, W. Richard Staines, Sean K. Meehan

“…Recent transcranial magnetic stimulation (TMS) studies suggest that variability in interneuron recruitment by anterior–posterior (AP) currents is linked to differences in functional connectivity between premotor and motor regions. …”
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Back-Analysis of Parameters of Jointed Surrounding Rock of Metro Station Based on Random Forest Algorithm Optimized by Cuckoo Search Algorithm by Xinping Guo, Annan Jiang, Xiang Liu

“…In this method, the mean square error between the measured displacement (stress) and the calculated displacement (stress) is taken as the objective function, and the joint parameters are taken as the decision variables. …”
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Parental acceptance of novel children's medical syringes and their influencing factors by Su Wen Luo, Peng Rui Yang

“…Furthermore, the product's function and price value significantly shape users' behavioral intentions. …”
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DeBo: Contrast enhancement for image registration using binary differential evolution and bat optimization. by Muhammad Adeel Akram, Tallha Akram, Umer Javed, Muhammad Rafiq, Mehvish Naz, Di He

“…In this study, we proposed a hybrid binary differential evolution and BAT optimization model to enhance contrast stretching by optimizing a decision variables in the transformation function. To validate its efficiency, the proposed approach is utilized as a preprocessor before feature extraction in image registration. …”
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PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival by Jeremiah L. Oyer, Tayler J. Croom-Perez, Md Faqrul Hasan, Javier A. Rivera-Huertas, Sarah B. Gitto, Joanna M. Mucha, Xiang Zhu, Deborah A. Altomare, Robert Y. Igarashi, Alicja J. Copik

“…This is typically done by ex vivo stimulation with cytokines to enhance functionality or expansion for 10-14 days to increase both their activity and quantity. …”
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Transcriptome profiling of Hyacinthus orientalis L. cultivars in floral pigmentation by Kwan-Ho Wong, Hoi-Yan Wu, Cheryl Wood-Yee Shum, Jerome Ho-Lam Hui, Pang-Chui Shaw, David Tai-Wai Lau

“…In addition, the usability of the dataset was demonstrated by the identification of differentially expressed genes, functional annotation and functional enrichment analysis. …”
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