TheraVision: Engineering platform technology for the development of oncolytic viruses based on herpes simplex virus type 1 by Christina Funk, Nadja Uhlig, Zsolt Ruzsics, Florentin Baur, Matthias Peindl, Sarah Nietzer, Karina Epting, Gabriele Vacun, Gudrun Dandekar, Catherine Botteron, Christian Werno, Thomas Grunwald, Susanne M. Bailer

“…Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. …”
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High-Resolution Core Gene-Associated Multiple Nucleotide Polymorphism (cgMNP) Markers for Strain Identification in the Wine Cap Mushroom <i>Stropharia rugosoannulata</i> by Fei Liu, Bin Cao, Hongmei Dai, Guojie Li, Shoumian Li, Wei Gao, Ruilin Zhao

“…Using core gene-associated multiple nucleotide polymorphism (cgMNP) markers, we developed an efficient and transferable framework for strain discrimination. …”
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A transient homotypic interaction model for the influenza A virus NS1 protein effector domain. by Philip S Kerry, Juan Ayllon, Margaret A Taylor, Claudia Hass, Andrew Lewis, Adolfo García-Sastre, Richard E Randall, Benjamin G Hale, Rupert J Russell

“…While RBD dimerization seems functionally conserved, two possible apo ED dimers have been proposed (helix-helix and strand-strand). …”
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A Fractional Time–Space Stochastic Advection–Diffusion Equation for Modeling Atmospheric Moisture Transport at Ocean–Atmosphere Interfaces by Behrouz Parsa Moghaddam, Mahmoud A. Zaky, António Mendes Lopes, Alexandra Galhano

“…The framework employs the Caputo fractional derivative to represent temporal persistence and the fractional Laplacian to model non-local turbulent diffusion, and incorporates a stochastic term with a <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><mn>1</mn><mo>/</mo><mi>f</mi></mrow></semantics></math></inline-formula> power spectral density to simulate environmental variability. An efficient numerical solution methodology is derived utilizing complementary Fourier and Laplace transforms, which elegantly converts spatial fractional operators into algebraic expressions and yields closed-form solutions via Mittag–Leffler functions. …”
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Optimal Design of Interior Permanent Magnet Synchronous Motor Considering Various Sources of Uncertainty by Giacomo Guidotti, Dario Barri, Federico Soresini, Massimiliano Gobbi

“…The method incorporates an innovative use of the neural network-based variance estimation (NNVE) technique to efficiently calculate the standard deviation of the objective functions. …”
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Building Credible VTOL Flight Models for Handling Quality Certification by Simulation by Lorenzo Favaro, Agata Rylko, Giuseppe Quaranta

“…Applied to a lift + cruise VTOL model performing a deceleration-to-hover manoeuvre, the study demonstrates that while longitudinal control dynamics largely remained within MUAD limits, indicating the model’s credibility for those aspects, vertical axis dynamics coupled with longitudinal inputs for some uncertain configurations exceeded these limits, correlating with observed flight test performance variability. Readers will find a structured, quantitative approach to model validation for HQ certification by simulation, leveraging MUAD to determine if a nominal model is sufficiently representative for certification, thereby supporting safer and more efficient VTOL development.…”
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The role of personalized precision medicine in enhancing diagnostic accuracy and clinical outcomes by Shamala Devi Sekaran, Rishya Manikam, Gaythri Thergerajan, Haymond Prasad, Munandy Alagar, Chung Keat Tan

“…Autologous or allogeneic stem cells such as mesenchymal stem cells and induced pluripotent stem cells can be used for direct tissue treatment in a rapid, personalized, and efficient manner. This approach of engineering cells and altering their functions before clinical use offers numerous benefits that are essential for personal health.…”
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A Brief Political Economy of Energy Subsidies in the Middle East and North Africa by Laura El-Katiri, Bassam Fattouh

“…While it is clear that energy subsidy reform will not be the only variable at play, its potential socio-economic dividends are important factors for enabling some common regional objectives—sustainable fiscal policies, fiscal space to invest in key areas, and a more efficient and equitable distribution of scarce resources—to be achieved, helping to promote a more stable political status quo in the long term. …”
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Classification of Biological Data using Deep Learning Technique by Azha Javed, Muhammad Javed Iqbal

“…Previous work failed to properly address issues related to the classification of biological sequences i.e. protein including efficient encoding of variable length biological sequence data and implementation of deep learning based neural network models to enhance the performance of classification/ recognition systems. …”
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Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. by Qi Chen, Luan Jiang, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du

“…The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists. …”
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Changes in AXL and/or MITF melanoma subpopulations in patients receiving immunotherapy by M. Willemsen, J. Bulgarelli, S.K. Chauhan, R.R. Lereim, D. Angeli, G. Grisendi, G. Krebbers, I. Davidson, J.A. Kyte, M. Guidoboni, R.M. Luiten, W.J. Bakker

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Advanced microfluidic strategies for core-shell nanoparticles: the next-generation of polymeric and lipid-based drug nanocarriers by Giuseppe Nunziata, Alessandro Borroni, Filippo Rossi

“…Microfluidic technology has transformed the synthesis of core-shell nanoparticles (CSNPs), providing an unprecedented level of control over their structural and functional properties. This review critically evaluates recent advancements, highlighting the superiority of microfluidic methods over conventional batch techniques, which often suffer from variability and scalability issues. …”
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La biodiversidad y los servicios ecosistémicos en sistemas agroecológicos. Una revisión by Wendy Mercedes Ramírez-Suárez, Jorge Carlos López-Chouza, María de los Ángeles Flores-Acosta, Saray Sánchez-Cárdenas, Pedro Lázaro Rodríguez-Morejón

“…There is a strong interrelationship between the functioning of biodiversity and the development of ecosystem processes that will subsequently form the basis of production, based on the richness and spatial and temporal variability of species, their performance in the complexity of ecosystems and the maintenance of ecosystem services at different scales.…”
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Symbolic Framework for Evaluation of NOMA Modulation Impairments Based on Irregular Constellation Diagrams by Nenad Stefanovic, Vladimir Mladenovic, Borisa Jovanovic, Ron Dabora, Asutosh Kar

“…This work presents a new symbolic framework approach for simulating signal processing functions in SDR transmit–receive paths in a dynamic NOMA downlink use case. …”
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Role of physical activity on the maintenance of cognition and activities of daily living in elderly with Alzheimer's disease Papel da atividade física na manutenção da cognição e a... by Cynthia Arcoverde, Andréa Deslandes, Aryce Rangel, Andreza Rangel, Robson Pavão, Fortunée Nigri, Eliasz Engelhardt, Jerson Laks

“…BACKGROUND: The practice of physical activities has proved to be an efficient strategy in the improvement of independency and cognitive functions in the elderly with Alzheimer's disease (AD). …”
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clonevdjseq: A workflow and bioinformatics management system for sequencing, archiving, and analysis of VDJ sequences from clonal libraries by Keith Mitchell, Samuel Hunter, Lutz Froenicke, Karl Murray, Matthew Settles, James S. Trimmer

“…The results of this effort has yielded sequences used to develop functional recombinant monoclonal antibodies and single chain variable fragments as a part of the NeuroMabSeq initiative where thousands of hybridoma samples were processed (Mitchell et al. in Sci Rep 13(1):16200, 2023) as well as provide additional modeling and extensibility to other modalities. …”
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Importance of ice algae versus phytoplankton in the diet of megabenthic organisms under contrasting sea ice conditions (Canadian Arctic): a dual biochemical approach (SIA and HBIs) by Thibaud Combaz, Thibaud Combaz, Ursula Witte, Thomas A. Brown, Philippe Archambault

“…Overall, organisms responded rapidly and efficiently to this pulse of fresh organic matter but trends in resource utilisation (quality and quantity) were observed based on feeding strategy. …”
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A Robust Multi-Objective Evolutionary Framework for Artificial Island Construction Scheduling Under Dynamic Constraints by Tianju Zheng, Liping Sun, Mingwei Li, Guangyao Yuan, Shuqi Li

“…MACEMGA combines cooperative coevolution, adaptive dynamic weighting, dynamic penalty functions, and advanced genetic operators to navigate the solution space efficiently and identify Pareto optimal schedules. …”
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Nitrogen deposition favors later leaf senescence in woody species by Jian Wang, Xiaoyue Wang, Josep Peñuelas, Hao Hua, Chaoyang Wu

“…Changes in climate conditions and nitrogen deposition levels jointly controlled the direction of date of foliar senescence trends (advance or delay). The spatial variability of nitrogen deposition effects can be related to plant traits (e.g., nitrogen resorption and use efficiencies), climatic conditions, and soil properties. …”
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Tumor-Associated Macrophages as Key Modulators of Disease Progression in Diffuse Large B-Cell Lymphoma by Corina Joldes, Laura Jimbu, Oana Mesaros, Mihnea Zdrenghea, Bogdan Fetica

“…Response to immunotherapy relies on the availability, functionality, and efficacy of the host’s immune effector mechanisms. …”
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