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  1. 481

    Genetically surface-modified Escherichia coli outer membrane vesicles targeting MUC1 antigen in cancer cells by Sedthawut Laotee, Wanatchaporn Arunmanee

    Published 2024-12-01
    “…In conclusion, this rapid and efficient bio-ligation system facilitates the display of functional scFv on OMV surfaces, offering a promising approach for targeted delivery to MUC1-expressing cancer cells.…”
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  2. 482

    Exploring the potentials of mango-orange leaf extract as an inhibitor on carbon steel in an acidic medium: Optimization, kinetics, and thermodynamics by Elijah Emeteveke Aghogho, Prosper Eguono Ovuoraye, Innocent Oseribho Oboh, Oluwafemi Osarhiemen Olayebi

    Published 2025-07-01
    “…The effects of optimized variables on corrosion inhibition were examined. The result confirmed optimum inhibition efficiency of 96 % corresponding to MOEx concentration, temperature, and time of 450 ppm, 30 0C, and 3 h recorded at an optimum acid concentration of 1.3 M of H2SO4. …”
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  3. 483

    Novel active-feedback device improves sleep quality in insomnia disorder: a randomized placebo-controlled trial by Antonia Ypsilanti, Maan van de Werken, Anna Robson, Petra Examilioti, Lambros Lazuras, Lambros Lazuras

    Published 2025-05-01
    “…ObjectivesInsomnia disorder is a public health challenge associated with impaired cognitive functioning, reduced quality of life, and adverse mental health outcomes. …”
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  4. 484

    qBiCo: a method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements by Faidra Karkala, Roy B. Simons, Floor Claessens, Vivian Kalamara, Manfred Kayser, Athina Vidaki

    Published 2025-01-01
    “…Depending on the starting DNA quantity, bisulfite-converted DNA recoveries ranged from 8.5 to 100%, conversion efficiencies from 78 to 99.9%, while certain kits highly fragment DNA, demonstrating large variability in their performance. …”
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  5. 485

    Different whole body HIIT protocols do not promote different muscle thickness and functional adaptations among healthy physically active subjects by Alexandre L. Evangelista, Júlio B. B. de Camargo, Roberta L. Rica, Luiz Carlos Carnevali Júnior, Gregg S. Mallett, Valentina Bullo, Marco Bergamin, Stefano Gobbo, Danilo S. Bocalini

    Published 2025-01-01
    “…Morphological (ultrasound-derived muscle thickness of the vastus lateralis [MTVL]) and general fitness (muscle endurance and maximal oxygen consumption) assessments were performed at pre- and post-intervention moments.ResultsBoth training protocols elicited significant improvements in all dependent variables (p < 0.05), with no significant between-group differences.ConclusionRegardless of the training configuration, both WB-HIIT programs serve as time-efficient strategies to induce changes in muscle thickness of the vastus lateralis and functional adaptations in healthy, physically active young individuals.…”
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  6. 486

    MULTI-OBJECTIVE OPTIMIZATION DESIGN FOR CUTTING MECHANISM OF ROADHEADER BASED ON IMPROVED GENETIC ALGORITHM by MAO Jun, PAN DeWen, XIE Miao, ZHENG GuangHui

    Published 2016-01-01
    “…The comprehensive performance of cutting mechanism of roadheader is decided by cutting dust,quantity of pick consumption,specific density consumption,load fluctuation and production efficiency. This paper takes motion parameters and structure parameters of cutting mechanism for design variables and optimizes multi-objective function of comprehensive performance of cutting mechanism based on the improved genetic algorithm. …”
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  7. 487

    Nonsense-mediated mRNA decay and loss-of-function of the protein underlie the X-linked epilepsy associated with the W356× mutation in synapsin I. by Maila Giannandrea, Fabrizia C Guarnieri, Niels H Gehring, Elena Monzani, Fabio Benfenati, Andreas E Kulozik, Flavia Valtorta

    Published 2013-01-01
    “…Given that the NMD efficiency is highly variable among individuals and cell types, we investigated also the effects of expression of the mutant protein and found that it is expressed at lower levels compared to wild-type synapsin I, forms perinuclear aggregates and is unable to reach presynaptic terminals in mature hippocampal neurons grown in culture. …”
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  8. 488

    Influence of heavy oil components and optimal magnetic nanocatalysts on the heavy oil upgrading by microwave-assisted by Parya Torkaman, Ramin Karimzadeh, Arezou Jafari

    Published 2025-09-01
    “…It indicates a slight loss in efficiency due to aggregation or degradation.…”
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  9. 489

    Statistical learning-driven parameter tuning in injection molding using modified simplex method by Pongchanun Luangpaiboon, Walailak Atthirawong, Anucha Hirunwat, Pasura Aungkulanon

    Published 2025-09-01
    “…The Taguchi design of experiments and desirability function analysis were employed to establish a baseline. …”
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  10. 490

    Transient decline and early recovery of noninvasive myocardial work after kidney transplantation: a prospective study by Yulin Huang, Lin Jin, Xinyan Qiu, Canying Yang, Luyi Ping, Zhengyao Jiang, Hua Zou, Zhihong Zhang, Jiwei Wang

    Published 2025-12-01
    “…NIMW parameters include global myocardial work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE).Results 1) Renal function indicators, including blood urea nitrogen, serum creatinine, and estimated glomerular filtration rate improved significantly at 10 days post-KT. …”
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  11. 491

    Eficiência técnica na suinocultura: efeitos dos gastos com meio ambiente e da renúncia fiscal Technical efficiency in swine breeding: effect of the expenses with the environment an... by Benedito D. Pereira, João C. de S. Maia, Rosalina Camilot

    Published 2008-04-01
    “…After estimating the technical efficiency indices with data of ten properties situated in Mato Grosso from production functions, whose dependent variable is represented by the production of swine and the independent ones are the consumption of water, electricity and the amount of workers directly tied with the productive process. …”
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  14. 494

    Pectin extraction from cocoa husk of different genotypes and stages of ripeness by Enrique Arévalo-Gardini, Cesar Oswaldo Arévalo-Hernández, Virupax Baligar, Dapeng Zhang

    Published 2025-07-01
    “…Results showed that genotype and ripeness significantly affect extraction efficiency and pectin functionality. The highest pectin yield was 77.7% for IMC-67 (ripe) and 72.6% for CCN51 (semi-ripe) at optimal conditions (pH 1.5–1.6, 80 °C, 75 minutes). …”
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  15. 495

    Optimal ANOVA-Based Emulators of Models With(out) Derivatives by Matieyendou Lamboni

    Published 2025-03-01
    “…Our emulators are also competitive in dealing with different distributions of the input variables and selecting inputs and interactions. Simulations show the efficiency of our approach.…”
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  18. 498

    Three-dimensional design, simulation and optimization of a centrifugal compressor impeller with double-splitter blades by Mohammadjavad Tasharrofi, Mojtaba Heidarian Shahri, Ali Madadi

    Published 2025-02-01
    “…Since the optimization process only using genetic algorithms is very time-consuming and has high computational costs, artificial neural networks were used to reduce costs. The objective function in this optimization process was to increase efficiency while maintaining the flow rate and pressure ratio at the design point. …”
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  19. 499

    Multifractal analysis of Bitcoin price dynamics by Cristian Bucur, Bogdan-George Tudorică, Adela Bâra, Simona-Vasilica Oprea

    Published 2025-02-01
    “… This research employs Multifractal Detrended Fluctuation Analysis (MFDFA) to investigate multifractal properties in financial variables, including Bitcoin prices and economic indicators. …”
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  20. 500

    Vehicle detection method based on multi-layer selective feature for UAV aerial images by Yinbao Ma, Yuyu Meng, Jiuyuan Huo

    Published 2025-07-01
    “…However, this task remains challenging due to variable high-altitude viewpoints, complex environmental interference, and limitations in algorithmic efficiency. …”
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