Three-dimensional dynamics of mesothelin-targeted CAR.CIK lymphocytes against ovarian cancer peritoneal carcinomatosis by Federica Galvagno, Valeria Leuci, Annamaria Massa, Chiara Donini, Ramona Rotolo, Sonia Capellero, Alessia Proment, Letizia Vitali, Andrea Maria Lombardi, Valentina Tuninetti, Lorenzo D’Ambrosio, Alessandra Merlini, Elisa Vigna, Giorgio Valabrega, Luca Primo, Alberto Puliafito, Dario Sangiolo

“…MSLN-CAR.CIK effectively killed and were functionally efficient against OC targets. In a “floating-like” 3D context with floating OC spheroids, both tumor localization and killing by MSLN-CAR.CIK were significantly boosted by fluid flow. …”
Get full text

Investigation into the monitoring and control of mechanical dynamics in inclined mining equipment utilizing digital twin technology by Panshi XIE, Hang YANG, Yongping WU, Baofa HUANG, Weidian LIN, Leilei YI

“…Ultimately, the feasibility and efficacy of this system are corroborated through a multi-functional, variable-angle large-scale "support-surrounding rock" system physical simulation platform. …”
Get full text

An updated non-intrusive, multi-scale, and flexible coupling interface in WRF 4.6.0 by S. Masson, S. Jullien, E. Maisonnave, D. Gill, G. Samson, M. Le Corre, L. Renault

“…The present paper details the development and the functionalities of the coupling interface we implemented in WRF. …”
Get full text

Enhanced prediction of heating value of municipal solid waste using hybrid neuro-fuzzy model and decision tree-based feature importance assessment by Oluwatobi Adeleke, Obafemi O. Olatunji, Tien-Chien Jen, Iretioluwa Olawuyi

“…To this end, the feature importance analysis of MSW input variables was carried out using the decision tree regressor with the Gini importance (GI) metrics to identify the most influential variable. …”
Get full text

Vibration Analysis of Rotating Tapered Timoshenko Beams by a New Finite Element Model by Bulent Yardimoglu

“…A new finite element model is developed and subsequently used for transverse vibrations of tapered Timoshenko beams with rectangular cross-section. The displacement functions of the finite element are derived from the coupled displacement field (the polynomial coefficients of transverse displacement and cross-sectional rotation are coupled through consideration of the differential equations of equilibrium) approach by considering the tapering functions of breadth and depth of the beam. …”
Get full text

RNAtango: Analysing and comparing RNA 3D structures via torsional angles. by Marta Mackowiak, Bartosz Adamczyk, Marta Szachniuk, Tomasz Zok

“…RNA molecules, essential for viruses and living organisms, derive their pivotal functions from intricate 3D structures. To understand these structures, one can analyze torsion and pseudo-torsion angles, which describe rotations around bonds, whether real or virtual, thus capturing the RNA conformational flexibility. …”
Get full text

Complete sequencing of the mitochondrial genome of tea plant Camellia sinensis cv. ‘Baihaozao’: multichromosomal structure, phylogenetic relationships, and adaptive evolutionary an... by Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zhiyin Chen, Zixu Wang, Zixu Wang, Zixu Wang, Zixu Wang, Wei Zhou, Wei Zhou, Wei Zhou, Wei Zhou, Sijie Liu, Sijie Liu, Sijie Liu, Sijie Liu, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yuxin Xiao, Yihui Gong, Yihui Gong, Yihui Gong, Yihui Gong

“…Adaptive evolutionary analysis, based on Ka/Ks ratios, was performed to investigate gene selection pressures.ResultsThe mitochondrial genome consists of 11 linear chromosomes, with a total length of 909,843 bp and a GC content of 45.62%. A total of 73 functional genes were annotated, among which 14 variable genes (e.g., ribosomal protein coding genes) retain intact functions without pseudogenization, which is rare among Theaceae plants. …”
Get full text

Optimal power flow using recent red-tailed hawk optimization algorithm by Ahmed M Nassef, Mohammad Ali Abdelkareem, Mohamed Louzazni

“…Optimization can efficiently achieve various objective functions in power systems. …”
Get full text

Research on the Stability Prediction and Optimization of CNC Milling Based on Bagging–NSGAⅡ Under the Influence of Multiple Factors by Congying DENG, Qian YOU, Yang ZHAO, Lijun LIN, Guofu YIN

“…Taking these process parameters (<italic>x</italic>, <italic>y</italic>, <italic>z</italic>, <italic>d</italic>, <italic>h</italic>, <italic>n</italic>, <italic>a</italic>_p, <italic>a</italic>_e, <italic>f</italic>_z) as design variables, a multi-objective optimization model is constructed to balance machining efficiency and tool life. …”
Get full text

Principal networks. by Jonathan D Clayden, Michael Dayan, Chris A Clark

“…This is an important problem because most cognitive functions would be expected to involve some but not all brain regions. …”
Get full text

Removal of caffeine from aqueous solution by green approach using Ficus Benjamina zero-valent iron/copper nanoparticles by Hossam Mohammed Abdel-Aziz, Rabie Saad Farag, Soha Ali Abdel-Gawad

“…Overall, FB-Fe/Cu is a committed green substance for removal Caffeine from aqueous solutions. Functional parameters affect investigated using the Linear regression analysis, we found them to account for over 98% of the variables affecting the removal procedure.…”
Get full text

Beyond Collaboration: The Impact of Partner Knowledge, Relational Skills, and Internal Communication on SME’s Performance by Marsiana Setiarini

“…Meanwhile, Internal Communication functions as a routine interaction mechanism that improves collaborative competence and accelerates organizational performance. …”
Get full text

Assessment of RBFs Based Meshfree Method for the Vibration Response of FGM Rectangular Plate Using HSDT Model by Manish Srivastava, Jeeoot Singh

“…Radial basis functions (RBFs) with modified radial distance are proposed for vibration analysis of functionally graded materials (FGM) rectangular plates. …”
Get full text

The modern concept of cognitive reserve by N. N. Koberskaya, G. R. Tabeeva

“…The main forms of cognitive impairment (CI) are characterized by a significant variability in the relationship between morphological changes and clinical manifestations. …”
Get full text

Fast Möbius transform: An algebraic approach to information decomposition by Abel Jansma, Pedro A. M. Mediano, Fernando E. Rosas

“…Our approach is based on a formula for estimating the Möbius function that circumvents important computational bottlenecks and can in some cases offer a double-exponential speedup. …”
Get full text

Underactuated Spatial Mechanism of Vehicle Door Latch with Force Constraint by Sulong Li, Lubin Hang, Mingyuan Wang, Xiaojie Huang

“…Aiming at less space occupation，efficient driving and high-end multi-function of the door latch release branch chain，the type synthesis of single loop spatial mechanism is carried out，and the RRRSR mechanism which could realize power release is obtained. …”
Get full text

Tranexamic acid impairs plasmin generation on human mesenchymal stem cells and derived membrane microvesicles, halting pericellular proteolysis by Ramy Abou Rjeily, Christina Mrad, Fatiha Z. El-Ghazouani, Florence Toti, Audrey Cras, Audrey Cras, Eduardo Angles-Cano

“…Cells thus obtained were seeded in multi-well plates and treated with different concentrations of plasminogen and pro-urokinase in the presence or absence of variable amounts of tranexamic acid. We measured MVs formation and phenotypical changes occurring on MSCs. …”
Get full text

Numerical solutions for fractional optimal control problems using Mü‎‎‎‎‎‎‎ntz-Legendre polynomials by Mohammad Sahabi, Allahbakhsh Yazdani Cherati

“…To achieve this, stable and efficient methods for calculating the fractional integral and derivative operators of Müntz-Legendre functions based on three-term recurrence formulas and Jacobi-Gauss quadrature rules are presented. …”
Get full text

Spatiotemporal changes of ecosystem health and the impact of its driving factors on the Loess Plateau in China by Xuepeng Zhang, Taixia Wu, Qiqi Du, Ninglei Ouyang, Wei Nie, Yang Liu, Peng Gou, Guangchao Li

“…Based on this idea, a new framework for assessing EH is proposed. The efficient machine learning model (light gradient boosting machine model) and the variable explanation model (SHapley Additive exPlanation model) are combined to quantify the functional relationships between various driving factors and EH, thereby exploring the impacts of climatic factors, socioeconomic development (SED), and ecological restoration projects (ERP) on EH. …”
Get full text

Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters by E. B. Myakoshina, I. G. Kulikova, N. V. Balatskaya, L. A. Katargina, S. V. Saakyan

“…A formula was calculated where P (z) is the value of the logistic function; Z, linear combination of symptoms; bo , intercept (free term), bi – regression coefficients for parameters Zi.P (z) = 1 : 1 + e – b0– b1z1– b2z2– b3z3– b4z4The logistic function increases monotonically and takes the values from 0 to 1 for any b and Z values [P∈ (0;1)]. …”
Get full text