MiR-216a-3p inhibits the cytotoxicity of primary natural killer cells by Rowan Abdelbary, Rowan Abdelbary, Manon Ragheb, Manon Ragheb, Shereen A. El Sobky, Nagwa El-Badri, Nourhan Aboud, Ahmed Tawheed, Asmaa Gomaa, Mona Zidan, Ramy K. Aziz, Abd Elrahman Abouzid, Radwa Ayman Salah, Mohamed El-Kassas, Imam Waked, Ahmed Moustafa, Ahmed Moustafa, Injie Omar Fawzy, Nada El-Ekiaby, Ahmed Ihab Abdelaziz

“…IntroductionThe role of miRNAs in regulating variable molecular functions has been sought by scientists for its promising utility in regulating the immune response and, hence, in treating various diseases. …”
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Neural Network-Based Design of a Buck Zero-Voltage-Switching Quasi-Resonant DC–DC Converter by Nikolay Hinov, Bogdan Gilev

“…The converter is a piecewise linear system mathematically described by Kirchhoff’s laws and represented through switching functions. In this way, a mathematical model is used to generate data on the behavior of the state variables obtained under various design parameters. …”
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Coordination of technology of railway operation of the Republic of Tajikistan and organization of railways in international traffic by P. N. Pulatov

“…Proposed classification of technological restrictions and controlled variables in the performance of transport takes into account methods for changing external conditions for the functioning of the railway landfill and methods for increasing internal efficiency of its operation. …”
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Modeling the contribution of micronekton diel vertical migrations to carbon export in the mesopelagic zone by H. Thibault, F. Ménard, J. Abitbol-Spangaro, J.-C. Poggiale, S. Martini

“…Several metabolic parameters accounted for most of the variability in micronekton biomass, organic carbon production, and transport efficiency, mostly linked to respiration rates and capture efficiency. …”
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Weather Phenomena Monitoring: Optimizing Solar Irradiance Forecasting With Temporal Fusion Transformer by Xinyang Hu

“…The proposed model decomposes the raw solar irradiance sequence into intrinsic mode functions using VMD and optimizes the TFT using the variable screening network and GRU-based encoder-decoder. …”
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Optimizing Constrained Engineering Optimization Problems Using Improved Mountain Gazelle Optimizer by Vu Hong Son Pham, Nghiep Trinh Nguyen Dang, Van Nam Nguyen

“…A comprehensive analysis was conducted using 12 functions from the CEC 2022 benchmark suite, and the algorithm was applied to five engineering problems, including the design of an I-beam, pressure vessel, three-bar truss, cantilever beam, and tension spring. …”
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Sparse Learning of the Disease Severity Score for High-Dimensional Data by Ivan Stojkovic, Zoran Obradovic

“…This problem is solved by addressing a dual formulation which is smooth and allows an efficient optimization. The proposed approach might be used as an effective and reliable tool for both scoring function learning and biomarker discovery, as demonstrated by identifying a stable set of genes related to influenza symptoms’ severity, which are enriched in immune-related processes.…”
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Energy factors affecting environmental pollution for sustainable development goals: The case of India by Vu Ngoc Xuan

“…The study used data from the World Bank from 2000 to 2023; the methodology adopted includes vector autoregression modeling, Granger causality tests, cointegration analysis, impulse response functions, and variance decomposition. These econometric techniques were selected due to their ability to capture dynamic relationships, determine causality, and identify long-term equilibrium among the variables. …”
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Non-Iterative Estimation of Multiscale Geographically and Temporally Weighted Regression Model by Ya-Di Dai, Hui-Guo Zhang

“…Simulation experiments are conducted to evaluate the performance of the proposed non-iterative method compared to traditional methods and the backfitting-based approach in terms of coefficient estimation accuracy and computational efficiency. The results demonstrate that the non-iterative estimation method for MGTWR significantly enhances computational efficiency while effectively capturing the scale effects of spatiotemporal variation in the regression coefficient functions for each predictor.…”
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Optimization of Material Flow and Product Allocation in Inter-Unit Operations: A Case Study of a Refrigerator Manufacturing Facility by Selman Karagoz, Yasin Karagoz

“…<i>Conclusions</i>: The proposed mathematical model supports the decision-making process by enabling adjustments to the proportions of functional areas within the manufacturing logistics system, ensuring operational efficiency and flexibility in response to changing demands. …”
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Generating Electricity with Hydraulically Amplified Self-Healing Electrostatic (HASEL) Transducers by Isabel Hess, Stephen Chamot, Blake Boren, Patrick Musgrave

“…This study identifies hydraulically amplified self-healing electrostatic (HASEL) transducers as electricity generators, contrary to their conventional role as actuators. HASELs are soft, variable-capacitance transducers inspired by biological muscles which were developed to mimic the flexibility and functionality of natural muscle tissues. …”
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Impacts of early postpartum behavioral patterns on the fertility and milk production of tropical dairy cows by Aqeel Raza, Kumail Abbas, Theerawat Swangchan-Uthai, Henk Hogeveen, Chaidate Inchaisri

“…Reproductive performance was analyzed using Cox proportional hazard models, while lactation dynamics were modeled using the Wood function to estimate peak yield, peak time, and persistency. …”
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Non-Similar Analysis of Boundary Layer Flow and Heat Transfer in Non-Newtonian Hybrid Nanofluid over a Cylinder with Viscous Dissipation Effects by Ahmed Zeeshan, Majeed Ahmad Yousif, Muhammad Imran Khan, Muhammad Amer Latif, Syed Shahzad Ali, Pshtiwan Othman Mohammed

“…Non-similar system of PDEs are obtained with efficient conversion variables. The dimensionless PDEs are truncated using a local non-similarity approach up to third level and numerical solution is evaluated using MATLAB built-in-function bvp4c. …”
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Optimization Study of PVT Coupled Water Loop Heat Pump Energy Supply System by Lv Tiangang, Liu Bing, Wu Jun, Zhu Li, Hou Jingxuan

“…By employing the Hooke-Jeeves algorithm, the system's design and operation parameters were optimized with annual cost and system COP as objective functions. Design variables included PVT inclination, azimuth, area, heat pump capacity, and tank volume, while operational variables were PVT backplate temperature and tank temperature. …”
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Optimization of K-Shaped Metal Sealing Ring for Subsea Tubing Hanger Based on Response Surface Method by Huan Xie, Hongxia Zhang, Yiwei Fan, Liyuan Liu, Wei Zeng

“…To address the issue of low optimization efficiency due to the need for repeated finite element calculations during the optimization process, quadratic response surface models are established for the sealing performance indicators of the K-shaped seal ring, which were then used as the optimization objective functions to enhance the optimization efficiency. …”
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Application of Optimization Algorithms in Voter Service Module Allocation by Edgar Jardón, Marcelo Romero, José-Raymundo Marcial-Romero

“…Allocation models are essential tools for optimally distributing client requests across multiple services under defined restrictions and objective functions. This study evaluates several heuristics to address an allocation problem involving young individuals reaching voting age. …”
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rcprd: An R package to simplify the extraction and processing of Clinical Practice Research Datalink (CPRD) data, and create analysis-ready datasets. by Alexander Pate, Rosa Parisi, Evangelos Kontopantelis, Matthew Sperrin

“…Functions are available to extract common variable types (e.g., history of a condition, or time until an event occurs, relative to an index date), and more general functions for database queries, allowing users to define their own variables for extraction. …”
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A Brief Political Economy of Energy Subsidies in the Middle East and North Africa by Laura El-Katiri, Bassam Fattouh

“…While it is clear that energy subsidy reform will not be the only variable at play, its potential socio-economic dividends are important factors for enabling some common regional objectives—sustainable fiscal policies, fiscal space to invest in key areas, and a more efficient and equitable distribution of scarce resources—to be achieved, helping to promote a more stable political status quo in the long term. …”
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Classification of Biological Data using Deep Learning Technique by Azha Javed, Muhammad Javed Iqbal

“…Previous work failed to properly address issues related to the classification of biological sequences i.e. protein including efficient encoding of variable length biological sequence data and implementation of deep learning based neural network models to enhance the performance of classification/ recognition systems. …”
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Haemodynamics-driven developmental pruning of brain vasculature in zebrafish. by Qi Chen, Luan Jiang, Chun Li, Dan Hu, Ji-wen Bu, David Cai, Jiu-lin Du

“…The brain blood vasculature consists of a highly ramified vessel network that is tailored to meet its physiological functions. How the brain vasculature is formed has long been fascinating biologists. …”
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