Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis. by Tomer Fekete, Neta Zach, Lilianne R Mujica-Parodi, Martin R Turner

“…Intra- as well as inter-motor functional networks in the 0.03-0.06 Hz frequency band were derived from 40 patients and 30 healthy controls of similar age, and used as features for pattern detection, employing multiple kernel learning. …”
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COVID-19-Associated Biventricular Takotsubo Syndrome Complicated with Cardiogenic Shock (Clinical Case) by E. M. Zeltyn-Аbramov, N. I. Belavina, N. N. Klochkova, R. T. Iskhakov, O. Yu. Evsyukov, L. Yu. Аrtyukhina, A. M. Svanadze, M. A. Lysenko

“…The presented case demonstrates a life-threatening TS pattern in patients with severe COVID-19. TPE procedure should be treated as a possible trigger of TS.…”
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Syntactic Analysis of Spatial Structure Characteristics of Traditional Villages Along the Yellow River in Western Shanxi Province by Chenge GAO, Fang WANG

“…This research explores the intrinsic connections between the spatial form and structure of traditional village settlements and between relevant cognitive and behavioral patterns, and explains the generation and evolution of landscape patterns, in an effort to enhance the understanding of the integration and centripetal degree of local and overall spatial functions within the village domain, the perceptibility of the spatial system, the consistency of behavioral experiences among residents and visitors, and the potential of local spaces to contribute to the overall spatial construction.MethodsThis research uses cluster sampling to select 33 national-level traditional villages in the four counties along the Yellow River in Lyuliang City, Shanxi Province, located on the eastern side of the Jin-Shaan Gorge in the middle reaches of the Yellow River. …”
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Chemogenetic tools for modulation of spatial learning in dopamine transporter deficient rats by Arina A. Gromova, Arina A. Gromova, Taisiia S. Shemiakova, Mikhail G. Khotin, Evgeniia N. Petrunina, Anastasia D. Belskaya, Raul R. Gainetdinov, Raul R. Gainetdinov, Natalia P. Kurzina, Anna B. Volnova, Anna B. Volnova

“…Variables such as the distance traveled, time taken to reach the goal box, number of errors and the perseverative patterns of activity were analyzed.ResultsNorepinephrine release from the LC to the PFC reduced hyperactive behavioral patterns in rats lacking the dopamine transporter (DAT-KO rats) with spontaneously elevated dopamine transmission. …”
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Identification of a metabolic brain network characterizing essential tremor by Solange Volnov, Hamzah Baagil, Oliver Winz, Hans-Juergen Kaiser, Sanne Katherina Meles, Joerg Bernhard Schulz, Kathrin Reetz, Felix Manuel Mottaghy, Florian Holtbernd

“…For network validation and to explore DBS effects, 8 additional ET patients (68.1 ± 8.2 years) treated with DBS were assessed in both the ON and OFF state, respectively. …”
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SURGICAL TECHNIQUE FOR COMPLEX SYNDACTYLY IN APERT SYNDROME: A SERIAL CASE by Williams Mesang, Agus Santoso Budi, Magda Rosalina Hutagalung

“…It is practically symmetrical causing significant dysfunction and infection if not treated properly. The goals in the treatment are the separation of independent digits without disturbing function and growth, the creation of a lined commissure, the provision of skin cover for the denuded nail edge and exposed bone, and to creation of aesthetically pleasing individual fingertips with proper nails, nail folds, and adequate pulp fullness. …”
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Hepatocyte necroptosis is associated with liver damage in dairy cows with ketosis by Menglin Liu, Jingmin Gu, Chenchen Zhao, Jinxia Li, Fanrong Kong, Xinyu Du, Dandan Qi, Enzhu Li, Jie Gao, Xiliang Du, Yuxiang Song, Guowen Liu, Wenwen Gao, Xinwei Li, Lin Lei

“…Necroptosis, a form of programmed cell death associated with cellular lysis, releases damage-associated molecular patterns (DAMP) into injured tissues, thereby amplifying inflammatory responses and tissue damage. …”
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A Case of Status Epilepticus in a Patient Experiencing an Acute Attack of Hereditary Angioedema by Danielle Weinberg, Steven Gayda, Kyle Hultz, Hanan Atia, Brian Kohen, Eric Boccio

“…Hereditary angioedema is inherited in an autosomal dominant pattern and results in a quantitative deficiency (HAE type I) or dysfunction (HAE type II) of the C1-esterase inhibitor (C1-INH) protein. …”
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Upper Crossed Syndrome and Scapulae Upper-Trapping: A Mesotherapy Protocol in Cervicoscapulobrachial Pain—The 8:1 Block by Luyddy Pires, Napoliane Santos, João Vitor Lana, Alex Pontes de Macedo, Fábio Ramos Costa, Gabriel Ohana Marques Azzini, Tomas Mosaner, Daniel de Moraes Ferreira Jorge, Gabriel Silva Santos, Arthur Medeiros, José Alexandre Reale Pereira, José Fábio Lana

“…Patients reported significant improvements in pain relief and functional outcomes, underscoring the clinical utility of the 8:1 block in treating cervicoscapulobrachialgia. This protocol offers a feasible, cost-effective intervention that enhances the efficacy of traditional therapeutic exercises by addressing underlying muscular and biomechanical dysfunctions. …”
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From hypertension to heart failure: The missed clues of transthyretin cardiac amyloidosis by Ambreen Gul, Kamran Dawood

“…NT-proBNP increased to 1204 ng/L, and cardiac troponin was mildly elevated at 28 ng/L.Electrocardiography (ECG) demonstrated a pseudo-infarct pattern (Fig 1). Repeat echocardiography revealed severe LVH with a restrictive filling pattern, raising suspicion of an infiltrative cardiomyopathy, such as cardiac amyloidosis. …”
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Autoimmune Pulmonary Alveolar Proteinosis: A Rare Diagnosis in Pediatric Age by Inês Pais-Cunha, Augusta Gonçalves, Sara Paulino, José Fontoura Matias, Silva Sónia, Catarina Ferraz, Inês Azevedo

“…Spirometry indicated a mild restrictive pattern (forced vital capacity [FVC] = 77%) and diffusing capacity of the lungs for carbon monoxide (DLCO) showed a moderate decrease at 48.6%. …”
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Neck and mind: exploring emotion processing in cervical dystonia by Federico Carbone, Marina Peball, Philipp Ellmerer, Beatrice Heim, Wolfgang Nachbauer, Elisabetta Indelicato, Matthias Amprosi, Philipp Mahlknecht, Anna Hussl, Anna Hotter, Roberta Granata, Klaus Seppi, Klaus Seppi, Atbin Djamshidian, Sylvia Boesch

“…ObjectiveA wide range of non-motor symptoms such as pain, mood disorders, insomnia, and executive dysfunction may occur in focal dystonia. Little is known, however, about emotional processing. …”
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Differential influence of 1,8-Cineol on distinct hypoxia-related immune alterations in human monocytes by Nele Jagodzinski, Anke Leichtle, Reinhard Depping, Kirstin Plötze-Martin, Samer G. Hakim, Karl-Ludwig Bruchhage, Ralph Pries

“…Furthermore, the secretion patterns of a variety of chemokines and cytokines were evaluated. …”
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Long-term Patient-reported Functional Outcome after Pelvic Ring Injuries: Analysis using Two Different Types of Outcome Scores by Sameer Aggarwal, Lav Mehta, Sandeep Patel, Vishal Kumar, Prasoon Kumar

“…Patient’s demographic profile, mode and pattern of injury, associated injuries, management, and complications were recorded. …”
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Case Report: A 55 kg retroperitoneal liposarcoma by Ren Yingzheng, An Junjie, Wang Guifei, Yang Yang, Dong Long, Jiang Linlin, Fang Zhiqiang, Bi Xiaogang, Dong Yonghong

“…The peak value of the abdominal circumference reached 165 cm. Abdominal and pelvic CT examination indicated that there was a huge mass with mixed density in the abdominal and pelvic cavity, which contained lipid, calcification, and soft tissue density shadows. …”
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Clinical and Laboratory Features, Treatment and Prognosis in Children with Guillian-Barre Syndrome by N. A. Suponeva, A. K. Shakaryan, A. V. Rakhteenko, M. A. Piradov, I. V. Mitrofanova, M. I. Prytkova, I. Ya. Leont’ieva, S. V. Shakhgildyan, N. S. Morozova

“…Cranial nerve dysfunction at nadir was observed in a greater percentage of patients (51%) compared to that of 23% cases at the onset, with the facial palsy increasing from 10 to 32% and the bulbar palsy from 12 to 19%. …”
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Clinical Features of Liver Injury Induced by Immune Checkpoint Inhibitors in Japanese Patients by Koji Imoto, Motoyuki Kohjima, Tomonobu Hioki, Tomoyuki Kurashige, Miho Kurokawa, Shigeki Tashiro, Hideo Suzuki, Akifumi Kuwano, Masatake Tanaka, Seiji Okada, Masaki Kato, Yoshihiro Ogawa

“…Methods. Among 387 patients treated with ICIs, those who developed drug-induced liver injury were investigated. …”
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Comparative effect of dietary fortification of raw and roasted seeds of pumpkin (Cucurbita pepo L) on fertility biomolecules in cisplatin-induced spermatotoxic rats by Seun Funmilola Akomolafe, Mary Aderonke Bola Ogundare, Ibikunle Akinlua, Oluwadamilare Oluwaseun Ajayi, Elijah Olalekan Odesanmi, Olusola Bolaji Adewale

“…However, studies have shown that dietary pattern plays a pivotal role in the protection of chemotherapy-induced testicular damage, and till date no report on the comparative effect of raw and roasted pumpkin seeds against chemotherapy-induced male infertility and reproductive dysfunction. …”
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Effectiveness in routine care: trauma-focused treatment for PTSD by Antje Krüger-Gottschalk, Sascha T. Kuck, Anne Dyer, Georg W. Alpers, Andre Pittig, Nexhmedin Morina, Thomas Ehring

“…This trial demonstrates its broad applicability among individuals with diverse patterns of clinical characteristics and comorbidities.…”
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Impact of Extracorporeal Detoxification on the Serum Levels of Microbial Aromatic Acid Metabolites in Sepsis by S. E. Khoroshilov, N. V. Beloborodova, A. V. Nikulin, A. Yu. Bedova

“…Ten patients with acute or chronic (end stage) renal failure that had developed in the presence of severe sepsis, infective and toxic shock, long term extracorporeal circulation, postresuscitation disease, etc. were prospectively examined and treated. All the patients underwent extracorporeal detoxification; the choice of its technique was determined from their past medical history and intoxication patterns. …”
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