Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer by Xuezeng Sun, Haifeng Dong, Rishun Su, Jingyao Chen, Wenchao Li, Songcheng Yin, Changhua Zhang

“…The group with lower risk showed increased Tumor Immune Dysfunction and Exclusion (TIDE) score and greater responsiveness to immunotherapy. …”
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Appropriateness of Antiplatelet Therapy and Proton Pump Inhibitor Prescribing in End-Stage Kidney Disease: A Retrospective Quality Investigation Study by Michael Che, Sumaiya Ahmed, Ryan Chan, Ayub Akbari, Deborah Zimmerman

“…Overall, it appears that prescribing patterns of DAPT and PPI at our center are unlikely to be a major contributor to the known increased risk of gastrointestinal bleeding in patients treated with hemodialysis. …”
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Clinical features of non-compaction cardiomyopathy across age groups: a retrospective study of 415 patients by Ying Li, Jimei Chen, Min Qiu, Miao Tian, Ziqin Zhou, Ruyue Zhang, Jiazichao Tu, Linjiang Han, Shuheng Zhou, Xinming Li, Jian Zhuang, Shusheng Wen

“…A significant correlation was observed between both LVESD and LVEDD measurements and MR area in patients with NCM (p<0.05).Conclusion Patients with NCM with concomitant MR consistently exhibited left ventricular dilatation and systolic dysfunction across all age groups. Significant age-related variations were observed in clinical presentations, arrhythmia patterns and the prevalence of congenital and valvular heart disease. …”
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The impact of armed conflict on maternal morbidity and mortality at a teaching hospital in the Tigray region of Ethiopia: a pre-war and wartime comparative analysis by Hale Teka, Mohamedawel Mohamedniguss Ebrahim, Rahel Nardos, Awol Yemane Legesse, Yibrah Berhe, Haileselassie Berhe, Mulugeta Gebregziabher, Gebre-Egziabher Kiros

“…Key indicators of severe maternal outcomes and patterns of organ dysfunction and critical interventions were examined. …”
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Gradient changes in bioprosthetic valve thrombosis: duration of anticoagulation and strategies to improve detection by Vuyisile T Nkomo, Alexander C Egbe, Heidi M Connolly, Patricia A Pellikka, Sorin V Pislaru, Filip Ionescu, Hartzell V Schaff, Ioana Petrescu, Jwan A Naser, Cristina Pislaru

“…We set forth to (1) evaluate patterns of increase in gradients prior to BPVT diagnosis and (2) characterise time-course of response to anticoagulation.Methods Patients treated with warfarin for BPVT (1999–2019) with clinically significant reduction of mean gradients (≥25%) were identified retrospectively. …”
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Acute necrotizing calculous cholecystitis after treatment with ceftriaxone in an elderly patient: a case report by Tsunehiko Shigemori, Ichiro Imoto, Yasuhiro Inoue, Ryo Nishiwaki, Natsuko Sugimasa, Tetsuya Hamaguchi, Midori Noji, Kenji Takeuchi, Yoshiyuki Ito, Taro Yasuma, Esteban C. Gabazza, Toshio Kato

“…A comparative analysis of the infrared spectroscopic pattern of the composition of gallstones collected during surgery with that of the ceftriaxone powder revealed that both have very similar infrared spectroscopic patterns. …”
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Temporal changes of spinal microglia in murine models of neuropathic pain: a scoping review by Simran Dhir, Simran Dhir, Hannah Derue, Hannah Derue, Alfredo Ribeiro-da-Silva, Alfredo Ribeiro-da-Silva

“…Neuropathic pain (NP) is an ineffectively treated, debilitating chronic pain disorder that is associated with maladaptive changes in the central nervous system, particularly in the spinal cord. …”
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Reliability of Scapula Clinical Assessment and Effectiveness of Scapular-Focused Exercises in a Non-Athletic Population with Shoulder Pain – a Literature Review by Maciej Olszewski, Sara Gamrot, Joanna Golec, Elżbieta Szczygieł

“…Scapular movement abnormalities have been defined as scapular dyskinesis. It is treated as a dysfunction that increases the risk of shoulder pain. …”
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Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris by Agata Lesiak, Paulina Paprocka, Urszula Wnorowska, Angelika Mańkowska, Grzegorz Król, Katarzyna Głuszek, Ewelina Piktel, Jakub Spałek, Jakub Spałek, Sławomir Okła, Sławomir Okła, Krzysztof Fiedoruk, Bonita Durnaś, Bonita Durnaś, Robert Bucki

“…We hypothesized that the increased expression of AMPs and their patterns in AV act as a compensatory mechanism to protect the skin with an impaired permeability barrier. …”
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Resistant Hypertension and Obstructive Sleep Apnea by Akram Khan, Nimesh K. Patel, Daniel J. O’Hearn, Supriya Khan

“…The mechanism proposed is a pattern of intermittent hypoxia associated with hyperaldosteronism, increased sympathetic tone, endothelial dysfunction, and inflammation. …”
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Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis by Takuya Murao, Gaifeng Ma, Atsushi Murao, Alok Jha, Jingsong Li, Yongchan Lee, Mian Zhou, Ping Wang, Ping Wang, Monowar Aziz, Monowar Aziz

“…Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. …”
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Clinical characteristics and epilepsy in genomic imprinting disorders: Angelman syndrome and Prader–Willi syndrome by Tzong-Shi Wang, Wen-Hsin Tsai, Li-Ping Tsai, Shi-Bing Wong

“…For PWS patients, epilepsy is not common and easy to treat. Conversely, AS is a single-gene disorder induced by ubiquitin-protein ligase E3A dysfunction, which only expresses from a maternal allele. …”
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Social-demographic factors and nursing diagnosis in patients with kidney transplant by Ana Luisa Brandão de Carvalho Lira, Marcos Venícios de Oliveira Lopes, Lúcia de Fátima da Silva, Thelma Leite de Araujo

“…Ten diagnosis presented frequency above the 75th percentile: risk of Infection; disturbed sensory perception; visual; hearing; Sleep pattern disturbance; Imbalanced nutrition; fatigue; sexual dysfunction; disturbed sensory perception: acute pain, more than body requirements; The nursing diagnosis study contributes to increasing the knowledge of realty of these patients, which is a necessary step for the establishment of nursing assistance to the renal transplanted, as well as for the direction of outcomes to be reached aiming the improvement of life quality.  …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

“…Methods To establish the multifaceted cardioprotective function and underlying mechanisms of TZPD against hyperglycemia (HG)—or senescence (SC)-induced cardiac dysfunction, H9c2 cells were treated with and without TZPD. …”
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Family Life Experiences of Children After Divorce: A Qualitative Research Parental Alienation by Sümeyra Ceylan Dolanbay, Aslıhan Aykara

“…The findings indicate that dysfunctional interaction patterns within the family witnessed prior to the before divorce period are related to the grounding of alienation experiences. …”
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Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Wheel runs were measured, and weekly average rotations, distance, and circadian patterns were analysed. Indirect calorimetry was performed pre‐ and post‐intervention. …”
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NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY by M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko

“…The observational retrospective study included 218 patients (190 girls and 28 boys) with juvenileonset SLE who were treated at the Pediatric Department of the V.A. Nasonova Research Institute of Rheumatology in the period from 1992 to 2017. …”
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The Effects of Caffeine Toxicity on The Liver in WistarRats by Innih, S.O.*, Calmday-Ombo, D.

“…Groups B, C and D were the caffeine intoxicated groups treated with 200, 400, and 800mg/kg body weight of caffeine. …”
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A Case Report of IgG4-related Disease With Common Clinical Manifestation in an Atypical Gender by Seyed Reza Najafizadeh, Maryam Yaseri

“…Biopsy of mass revealed infiltrates with IgG4 plasma cells, consistent with the diagnosis of IgG4-RD. The patients were treated with steroids and rituximab, and the results showed significant improvement.  …”
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Fever as a Catalyst for Life‐Threatening Arrhythmias in Brugada Syndrome: A Rare Case of Brugada Syndrome Unmasked in a Young Male by Ibrahim Khalil, Md. Imran Hossain

“…His temperature was recorded at 39°C, and a 12‐lead ECG revealed a Type 1 Brugada pattern, confirming a fever‐triggered BrS diagnosis. …”
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