Lactylation-related gene signature accurately predicts prognosis and immunotherapy response in gastric cancer by Xuezeng Sun, Haifeng Dong, Rishun Su, Jingyao Chen, Wenchao Li, Songcheng Yin, Changhua Zhang

“…The group with lower risk showed increased Tumor Immune Dysfunction and Exclusion (TIDE) score and greater responsiveness to immunotherapy. …”
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Neck and mind: exploring emotion processing in cervical dystonia by Federico Carbone, Marina Peball, Philipp Ellmerer, Beatrice Heim, Wolfgang Nachbauer, Elisabetta Indelicato, Matthias Amprosi, Philipp Mahlknecht, Anna Hussl, Anna Hotter, Roberta Granata, Klaus Seppi, Klaus Seppi, Atbin Djamshidian, Sylvia Boesch

“…ObjectiveA wide range of non-motor symptoms such as pain, mood disorders, insomnia, and executive dysfunction may occur in focal dystonia. Little is known, however, about emotional processing. …”
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Long-term Patient-reported Functional Outcome after Pelvic Ring Injuries: Analysis using Two Different Types of Outcome Scores by Sameer Aggarwal, Lav Mehta, Sandeep Patel, Vishal Kumar, Prasoon Kumar

“…Patient’s demographic profile, mode and pattern of injury, associated injuries, management, and complications were recorded. …”
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Appropriateness of Antiplatelet Therapy and Proton Pump Inhibitor Prescribing in End-Stage Kidney Disease: A Retrospective Quality Investigation Study by Michael Che, Sumaiya Ahmed, Ryan Chan, Ayub Akbari, Deborah Zimmerman

“…Overall, it appears that prescribing patterns of DAPT and PPI at our center are unlikely to be a major contributor to the known increased risk of gastrointestinal bleeding in patients treated with hemodialysis. …”
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Clinical features of non-compaction cardiomyopathy across age groups: a retrospective study of 415 patients by Ying Li, Jimei Chen, Min Qiu, Miao Tian, Ziqin Zhou, Ruyue Zhang, Jiazichao Tu, Linjiang Han, Shuheng Zhou, Xinming Li, Jian Zhuang, Shusheng Wen

“…A significant correlation was observed between both LVESD and LVEDD measurements and MR area in patients with NCM (p<0.05).Conclusion Patients with NCM with concomitant MR consistently exhibited left ventricular dilatation and systolic dysfunction across all age groups. Significant age-related variations were observed in clinical presentations, arrhythmia patterns and the prevalence of congenital and valvular heart disease. …”
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Gradient changes in bioprosthetic valve thrombosis: duration of anticoagulation and strategies to improve detection by Vuyisile T Nkomo, Alexander C Egbe, Heidi M Connolly, Patricia A Pellikka, Sorin V Pislaru, Filip Ionescu, Hartzell V Schaff, Ioana Petrescu, Jwan A Naser, Cristina Pislaru

“…We set forth to (1) evaluate patterns of increase in gradients prior to BPVT diagnosis and (2) characterise time-course of response to anticoagulation.Methods Patients treated with warfarin for BPVT (1999–2019) with clinically significant reduction of mean gradients (≥25%) were identified retrospectively. …”
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Acute necrotizing calculous cholecystitis after treatment with ceftriaxone in an elderly patient: a case report by Tsunehiko Shigemori, Ichiro Imoto, Yasuhiro Inoue, Ryo Nishiwaki, Natsuko Sugimasa, Tetsuya Hamaguchi, Midori Noji, Kenji Takeuchi, Yoshiyuki Ito, Taro Yasuma, Esteban C. Gabazza, Toshio Kato

“…A comparative analysis of the infrared spectroscopic pattern of the composition of gallstones collected during surgery with that of the ceftriaxone powder revealed that both have very similar infrared spectroscopic patterns. …”
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Temporal changes of spinal microglia in murine models of neuropathic pain: a scoping review by Simran Dhir, Simran Dhir, Hannah Derue, Hannah Derue, Alfredo Ribeiro-da-Silva, Alfredo Ribeiro-da-Silva

“…Neuropathic pain (NP) is an ineffectively treated, debilitating chronic pain disorder that is associated with maladaptive changes in the central nervous system, particularly in the spinal cord. …”
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Reliability of Scapula Clinical Assessment and Effectiveness of Scapular-Focused Exercises in a Non-Athletic Population with Shoulder Pain – a Literature Review by Maciej Olszewski, Sara Gamrot, Joanna Golec, Elżbieta Szczygieł

“…Scapular movement abnormalities have been defined as scapular dyskinesis. It is treated as a dysfunction that increases the risk of shoulder pain. …”
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Case Report: A 55 kg retroperitoneal liposarcoma by Ren Yingzheng, An Junjie, Wang Guifei, Yang Yang, Dong Long, Jiang Linlin, Fang Zhiqiang, Bi Xiaogang, Dong Yonghong

“…The peak value of the abdominal circumference reached 165 cm. Abdominal and pelvic CT examination indicated that there was a huge mass with mixed density in the abdominal and pelvic cavity, which contained lipid, calcification, and soft tissue density shadows. …”
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Clinical and Laboratory Features, Treatment and Prognosis in Children with Guillian-Barre Syndrome by N. A. Suponeva, A. K. Shakaryan, A. V. Rakhteenko, M. A. Piradov, I. V. Mitrofanova, M. I. Prytkova, I. Ya. Leont’ieva, S. V. Shakhgildyan, N. S. Morozova

“…Cranial nerve dysfunction at nadir was observed in a greater percentage of patients (51%) compared to that of 23% cases at the onset, with the facial palsy increasing from 10 to 32% and the bulbar palsy from 12 to 19%. …”
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Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris by Agata Lesiak, Paulina Paprocka, Urszula Wnorowska, Angelika Mańkowska, Grzegorz Król, Katarzyna Głuszek, Ewelina Piktel, Jakub Spałek, Jakub Spałek, Sławomir Okła, Sławomir Okła, Krzysztof Fiedoruk, Bonita Durnaś, Bonita Durnaś, Robert Bucki

“…We hypothesized that the increased expression of AMPs and their patterns in AV act as a compensatory mechanism to protect the skin with an impaired permeability barrier. …”
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Resistant Hypertension and Obstructive Sleep Apnea by Akram Khan, Nimesh K. Patel, Daniel J. O’Hearn, Supriya Khan

“…The mechanism proposed is a pattern of intermittent hypoxia associated with hyperaldosteronism, increased sympathetic tone, endothelial dysfunction, and inflammation. …”
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Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis by Takuya Murao, Gaifeng Ma, Atsushi Murao, Alok Jha, Jingsong Li, Yongchan Lee, Mian Zhou, Ping Wang, Ping Wang, Monowar Aziz, Monowar Aziz

“…Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. …”
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Clinical characteristics and epilepsy in genomic imprinting disorders: Angelman syndrome and Prader–Willi syndrome by Tzong-Shi Wang, Wen-Hsin Tsai, Li-Ping Tsai, Shi-Bing Wong

“…For PWS patients, epilepsy is not common and easy to treat. Conversely, AS is a single-gene disorder induced by ubiquitin-protein ligase E3A dysfunction, which only expresses from a maternal allele. …”
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Social Media and Men’s Health: Separating Science from Speculation in Andrology by Michael George, Vaibhav Modgil, Ian Pearce, Theodora Stasinou

“…Key men’s health topics such as infertility, erectile dysfunction, testosterone supplementation and semen retention are popular amongst social media posts, amassing millions-to-billions of views depending on the platform. …”
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The dual GLP-1 and GIP receptor agonist tirzapetide provides an unintended interaction with the β-adrenoceptors and plays a role in glucose metabolism in hyperglycemic or senescent... by Dunya Aydos, Zeynep Busra Aksoy, Mehmet Altay Unal, Kamil Can Akcali, Ceylan Verda Bitirim, Belma Turan

“…Methods To establish the multifaceted cardioprotective function and underlying mechanisms of TZPD against hyperglycemia (HG)—or senescence (SC)-induced cardiac dysfunction, H9c2 cells were treated with and without TZPD. …”
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Voluntary Activity Wheel Running Improves Hyperammonaemia‐Induced Skeletal Muscle Molecular and Metabolic Perturbations in Mice by Annette Bellar, Avinash Kumar, Khaviyaa Chandramohan, Saurabh Mishra, Muaz Alsabbagh‐Alchirazi, Artem Astafev, Pugazhendhi Kannan, Amy Attaway, Roman Kondratov, Thomas Jaramillo, Lopa Mishra, Takhar Kasumov, Nicole Welch, Srinivasan Dasarathy

“…Wheel runs were measured, and weekly average rotations, distance, and circadian patterns were analysed. Indirect calorimetry was performed pre‐ and post‐intervention. …”
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NEUROPSYCHIATRIC DISORDERS IN JUVENILE-ONSET SYSTEMIC LUPUS ERYTHEMATOSUS: RESULTS FROM A RETROSPECTIVE STUDY by M. I. Kaleda, I. P. Nikishina, S. I. Glukhova, N. Yu. Stepanenko

“…The observational retrospective study included 218 patients (190 girls and 28 boys) with juvenileonset SLE who were treated at the Pediatric Department of the V.A. Nasonova Research Institute of Rheumatology in the period from 1992 to 2017. …”
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The Effects of Caffeine Toxicity on The Liver in WistarRats by Innih, S.O.*, Calmday-Ombo, D.

“…Groups B, C and D were the caffeine intoxicated groups treated with 200, 400, and 800mg/kg body weight of caffeine. …”
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