-
41
Effects of antagonistic network-targeted tDCS on brain co-activation patterns depends on the networks’ electric field: a simultaneous tDCS-fMRI study
Published 2025-08-01“…Six recurring brain patterns (co-activation patterns, CAPs) were identified. …”
Get full text
Article -
42
Wearable peripheral nerve stimulator reduces essential tremor symptoms through targeted brain modulation
Published 2025-07-01“…Background: Essential tremor (ET), the most common movement disorder in adults, presents with involuntary shaking of the upper extremities during postural hold and kinetic tasks linked to dysfunction in the cerebello-thalamo-cortical network. …”
Get full text
Article -
43
-
44
Estudio comparativo de las funciones ejecutivas entre pacientes con enfermedad de Parkinson y pacientes con enfermedad degenerativa cerebelosa Comparison study of executive functio...
Published 2006-09-01“…On the other hand the PD group showed a selective increase of non perseverative errors, without reaching significant between group difference. CONCLUSION: The CD group appears to have greater deficits in EF with a pattern of prefrontal dysfunction.…”
Get full text
Article -
45
Clinical outcomes of the tunica albuginea plication for patients with Peyronie’s disease: a bicentric retrospective analysis
Published 2025-05-01“…Patients with complex curvature patterns had a higher risk of reoperation. Conclusions Plication surgery is an effective and safe option for treating penile curvature in Peyronie’s disease, particularly in patients with more severe deformities. …”
Get full text
Article -
46
Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats
Published 2025-05-01“…Our study not only provides a mechanistic basis for the clinical efficacy of acupuncture in treating ovarian disorders but also identifies ISF dynamics as a novel therapeutic target in age-related ovarian dysfunction.…”
Get full text
Article -
47
Agomelatine: A review for general practitioners
Published 2012-06-01“…Agomelatine is a melatonin 1 (MT1) and melatonin 2 (MT2) receptor agonist and serotonin (5-hydroxytryptamine) 2C (5-HT2C) receptor antagonist. It is effective in treating moderate-to-severe depression, alleviating the symptoms of anxiety, and restoring the disrupted sleep patterns that often result from this potentially devastating disease. …”
Get full text
Article -
48
Atrioventricular Conduction Abnormalities in Multisystem Inflammatory Syndrome in Children
Published 2021-01-01“…Cardiac manifestations in multisystem inflammatory syndrome in children (MIS-C) can include coronary artery aneurysms, left ventricular systolic dysfunction, and electrocardiographic disturbances. …”
Get full text
Article -
49
Transvertebral magnetic neuromodulation for the treatment of overactive bladder: 6 months follow-up
Published 2020-12-01“…The most common type of lower urinary tract dysfunction is an overactive bladder (OAB). Today there is a need to search for new effective methods of treating this disease.Purpose of the study. …”
Get full text
Article -
50
Disseminated intravascular coagulation
Published 2025-06-01“…Conversely, these pathogenic pathways and DIC synergistically contribute to organ dysfunction, leading to poor prognoses. Effective DIC management requires treating the underlying condition, along with substitution therapies and, in some cases, antifibrinolytics. …”
Get full text
Article -
51
Acupuncture treatment for functional gastrointestinal disorders: Identification of major acupoints using network analysis
Published 2023-09-01“…These findings could be applied in future acupuncture research on therapy for gastrointestinal system dysfunction. They may also help bridge the gap between the traditional meridian theory, which assumes that there is a link between diseases/symptoms and the specific body region being treated, and real-world clinical evidence.…”
Get full text
Article -
52
A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies
Published 2025-06-01“…Among individuals diagnosed with TAO, about 90% have Graves’ hyperthyroidism, while a smaller percentage may have primary hypothyroidism, Hashimoto’s thyroiditis, or normal thyroid function. These patterns emphasise the importance of recognising thyroid dysfunction in orbitopathy management which includes treating the underlying thyroid dysfunction, using corticosteroids to reduce inflammation, and applying artificial tears for symptomatic relief. …”
Get full text
Article -
53
The Effect of Audible Joint Manipulation Sounds in the Upper Cervical Spine on Brain Wave and Autonomic Nervous System Activity
Published 2025-01-01“…Background: High-velocity, low-amplitude (HVLA) manipulation is a common manual therapy technique used for treating pain and musculoskeletal dysfunction. An audible manipulation sound is commonly experienced by patients who undergo HVLA manipulation; however, there is little known about the effects and clinical relevance of the audible manipulation sound on cortical output and the autonomic nervous system. …”
Get full text
Article -
54
Targeted discovery of gut microbiome-remodeling compounds for the treatment of systemic inflammatory response syndrome
Published 2024-10-01“…ABSTRACT Systemic inflammatory response syndrome (SIRS) is a severe inflammatory response that can lead to organ dysfunction and death. Modulating the gut microbiome is a promising therapeutic approach for managing SIRS. …”
Get full text
Article -
55
Health status and disability in persons with spinal cord injuries in South Africa and Kenya
Published 2024-09-01“…Results: In both countries, sexual dysfunction (55% – 57%), pain (48% – 49%), spasticity (41% – 42%) and bladder dysfunction (27% – 60%) emerged as the predominant secondary medical complications, with sexual dysfunction and pain showing overlap. …”
Get full text
Article -
56
Social-demographic factors and nursing diagnosis in patients with kidney transplant
Published 2009-02-01“…Ten diagnosis presented frequency above the 75th percentile: risk of Infection; disturbed sensory perception; visual; hearing; Sleep pattern disturbance; Imbalanced nutrition; fatigue; sexual dysfunction; disturbed sensory perception: acute pain, more than body requirements; The nursing diagnosis study contributes to increasing the knowledge of realty of these patients, which is a necessary step for the establishment of nursing assistance to the renal transplanted, as well as for the direction of outcomes to be reached aiming the improvement of life quality. …”
Get full text
Article -
57
Multiple kernel learning captures a systems-level functional connectivity biomarker signature in amyotrophic lateral sclerosis.
Published 2013-01-01“…Intra- as well as inter-motor functional networks in the 0.03-0.06 Hz frequency band were derived from 40 patients and 30 healthy controls of similar age, and used as features for pattern detection, employing multiple kernel learning. …”
Get full text
Article -
58
Investigating intra‐tumoural heterogeneity and microenvironment diversity in primary cardiac angiosarcoma through single‐cell RNA sequencing
Published 2024-12-01“…Key points Insights into the heterogeneity and transcriptional patterns of sarcoma cells may explain the challenges in treating primary cardiac angiosarcoma (PCAS) using the current therapeutic modalities. …”
Get full text
Article -
59
Impairment of neuronal activity in the dorsolateral prefrontal cortex occurs early in parkinsonism
Published 2025-01-01“…Little is known, however, regarding how neuronal activity in the executive control network of the brain changes in the parkinsonian condition.ObjectiveInvestigate the impact of parkinsonism on neuronal activity in the dorsolateral prefrontal cortex (DLPFC), a key region in executive control, during a go/nogo reaching task.MethodsUsing a within-subject design, single and multi-unit neuronal activity was recorded in the DLPFC of a nonhuman primate (n = 1) before and after the induction of mild parkinsonism using the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).ResultsCoincident with development of mild parkinsonian motor signs, there was a marked reduction in the percentage of DLPFC cells with significant task-related firing rate modulation during go and nogo conditions.ConclusionThese results suggest that DLPFC dysfunction may occur early in parkinsonism and contribute to cognitive impairments and disrupted executive function often observed in PD patients.…”
Get full text
Article -
60
Enhanced beta power emerges from simulated parkinsonian primary motor cortex
Published 2025-08-01“…Dysfunction in PT5B neurons, the final-common-pathway to brainstem and spinal cord, provides a new target to treat PD motor symptoms.…”
Get full text
Article